Author results

1FV9
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CRYSTAL STRUCTURE OF HUMAN MICROUROKINASE IN COMPLEX WITH 2-AMINO-5-HYDROXY-BENZIMIDAZOLE
分子名称:UROKINASE, SULFATE ION, 2-AMINO-5-HYDROXY-BENZIMIDAZOLE
著者Nienaber, V.
登録日2000-09-19
公開日2000-10-18
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Identification of novel inhibitors of urokinase via NMR-based screening.
J.Med.Chem., 43, 2000
5BJT
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CRYSTAL STRUCTURE OF HUMAN FCRN WITH A PEPTIDE INHIBITOR AT MULTIPLE SITES
分子名称:IgG receptor FcRn large subunit p51, Beta-2-microglobulin, peptide inhibitor
著者Nienaber, V., Badger, J.
登録日2016-10-23
公開日2017-03-22
最終更新日2017-04-19
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Hepatic FcRn regulates albumin homeostasis and susceptibility to liver injury.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1SQA
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SUBSTITUTED 2-NAPHTHAMIDINE INHIBITORS OF UROKINASE
分子名称:Urokinase-type plasminogen activator, SULFATE ION, 6-[(Z)-AMINO(IMINO)METHYL]-N-[4-(AMINOMETHYL)PHENYL]-4-(PYRIMIDIN-2-YLAMINO)-2-NAPHTHAMIDE
著者Wendt, M.D., Geyer, A., McClellan, W.J., Rockway, T.W., Weitzberg, M., Zhao, X., Stewart, K., Nienaber, V., Klinghofer, V., Giranda, V.L.
登録日2004-03-18
公開日2004-04-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Interaction with the S1beta-pocket of urokinase: 8-heterocycle substituted and 6,8-disubstituted 2-naphthamidine urokinase inhibitors.
Bioorg.Med.Chem.Lett., 14, 2004
1SQO
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SUBSTITUTED 2-NAPHTHAMIDINE INHIBITORS OF UROKINASE
分子名称:Urokinase-type plasminogen activator, SULFATE ION, 8-(PYRIMIDIN-2-YLAMINO)NAPHTHALENE-2-CARBOXIMIDAMIDE
著者Wendt, M.D., Geyer, A., McClellan, W.J., Rockway, T.W., Weitzberg, M., Zhao, X., Mantei, R., Stewart, K., Nienaber, V., Klinghofer, V., Giranda, V.L.
登録日2004-03-19
公開日2004-04-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Interaction with the S1beta-pocket of urokinase: 8-heterocycle substituted and 6,8-disubstituted 2-naphthamidine urokinase inhibitors.
Bioorg.Med.Chem.Lett., 14, 2004
1SQT
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SUBSTITUTED 2-NAPHTHAMIDINE INHIBITORS OF UROKINASE
分子名称:Urokinase-type plasminogen activator, 7-METHOXY-8-[1-(METHYLSULFONYL)-1H-PYRAZOL-4-YL]NAPHTHALENE-2-CARBOXIMIDAMIDE
著者Wendt, M.D., Geyer, A., McClellan, W.J., Rockway, T.W., Weitzberg, M., Zhang, X., Mantei, R., Stewart, K., Nienaber, V., Klinghofer, V., Giranda, V.L.
登録日2004-03-19
公開日2004-04-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Interaction with the S1beta-pocket of urokinase: 8-heterocycle substituted and 6,8-disubstituted 2-naphthamidine urokinase inhibitors.
Bioorg.Med.Chem.Lett., 14, 2004
3M17
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CRYSTAL STRUCTURE OF HUMAN FCRN WITH A MONOMERIC PEPTIDE INHIBITOR
分子名称:IgG receptor FcRn large subunit p51, Beta-2-microglobulin, monomeric peptide inhibitor
著者Mezo, A.R., Sridhar, V., Badger, J., Sakorafas, P., Nienaber, V.
登録日2010-03-04
公開日2010-06-16
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献X-ray crystal structures of monomeric and dimeric peptide inhibitors in complex with the human neonatal Fc receptor, FcRn.
J.Biol.Chem., 285, 2010
3M1B
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CRYSTAL STRUCTURE OF HUMAN FCRN WITH A DIMERIC PEPTIDE INHIBITOR
分子名称:IgG receptor FcRn large subunit p51, Beta-2-microglobulin, DIMERIC PEPTIDE INHIBITOR
著者Mezo, A.R., Sridhar, V., Badger, J., Sakorafas, P., Nienaber, V.
登録日2010-03-04
公開日2010-06-16
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献X-ray crystal structures of monomeric and dimeric peptide inhibitors in complex with the human neonatal Fc receptor, FcRn.
J.Biol.Chem., 285, 2010
3PMO
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THE STRUCTURE OF LPXD FROM PSEUDOMONAS AERUGINOSA AT 1.3 A RESOLUTION
分子名称:UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, 1,2-ETHANEDIOL, CHLORIDE ION
著者Badger, J., Chie-Leon, B., Logan, C., Sridhar, V., Sankaran, B., Zwart, P.H., Nienaber, V.
登録日2010-11-17
公開日2011-07-27
最終更新日2012-03-28
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献The structure of LpxD from Pseudomonas aeruginosa at 1.3 A resolution.
Acta Crystallogr.,Sect.F, 67, 2011
4E6T
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STRUCTURE OF LPXA FROM ACINETOBACTER BAUMANNII AT 1.8A RESOLUTION (P212121 FORM)
分子名称:Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, CITRATE ANION
著者Badger, J., Chie-Leon, B., Logan, C., Sridhar, V., Sankaran, B., Zwart, P.H., Nienaber, V.
登録日2012-03-15
公開日2012-12-12
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure determination of LpxA from the lipopolysaccharide-synthesis pathway of Acinetobacter baumannii.
Acta Crystallogr.,Sect.F, 68, 2012
4E6U
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STRUCTURE OF LPXA FROM ACINETOBACTER BAUMANNII AT 1.4A RESOLUTION (P63 FORM)
分子名称:Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, SULFATE ION, 1,2-ETHANEDIOL
著者Badger, J., Chie-Leon, B., Logan, C., Sridhar, V., Sankaran, B., Zwart, P.H., Nienaber, V.
登録日2012-03-16
公開日2012-12-12
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献Structure determination of LpxA from the lipopolysaccharide-synthesis pathway of Acinetobacter baumannii.
Acta Crystallogr.,Sect.F, 68, 2012
4E75
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STRUCTURE OF LPXD FROM ACINETOBACTER BAUMANNII AT 2.85A RESOLUTION (P21 FORM)
分子名称:UDP-3-O-acylglucosamine N-acyltransferase
著者Badger, J., Chie-Leon, B., Logan, C., Sridhar, V., Sankaran, B., Zwart, P.H., Nienaber, V.
登録日2012-03-16
公開日2013-01-16
最終更新日2013-02-20
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structure determination of LpxD from the lipopolysaccharide-synthesis pathway of Acinetobacter baumannii.
Acta Crystallogr.,Sect.F, 69, 2013
4E79
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STRUCTURE OF LPXD FROM ACINETOBACTER BAUMANNII AT 2.66A RESOLUTION (P4322 FORM)
分子名称:UDP-3-O-acylglucosamine N-acyltransferase
著者Badger, J., Chie-Leon, B., Logan, C., Sridhar, V., Sankaran, B., Zwart, P.H., Nienaber, V.
登録日2012-03-16
公開日2013-01-16
最終更新日2013-02-20
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Structure determination of LpxD from the lipopolysaccharide-synthesis pathway of Acinetobacter baumannii.
Acta Crystallogr.,Sect.F, 69, 2013
4FU7
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CRYSTAL STRUCTURE OF THE UROKINASE
分子名称:Urokinase-type plasminogen activator, SULFATE ION, ACETATE ION, ...
著者Kang, Y.N., Stuckey, J.A., Nienaber, V., Giranda, V.
登録日2012-06-28
公開日2012-08-22
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of the Urokinase
to be published
4FU8
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CRYSTAL STRUCTURE OF THE UROKINASE
分子名称:Urokinase-type plasminogen activator, naphthalene-2-carboximidamide, ACETATE ION, ...
著者Kang, Y.N., Stuckey, J.A., Nienaber, V., Giranda, V.
登録日2012-06-28
公開日2012-08-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of the Urokinase
to be published
4FU9
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CRYSTAL STRUCTURE OF THE UROKINASE
分子名称:Urokinase-type plasminogen activator, SULFATE ION, SUCCINIC ACID, ...
著者Kang, Y.N., Stuckey, J.A., Nienaber, V., Giranda, V.
登録日2012-06-28
公開日2012-08-22
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal Structure of the Urokinase
To be Published
4FUB
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CRYSTAL STRUCTURE OF THE UROKINASE
分子名称:Urokinase-type plasminogen activator, 6-[(2S,3S)-3-phenyloxiran-2-yl]naphthalene-2-carboximidamide, SULFATE ION, ...
著者Kang, Y.N., Stuckey, J.A., Nienaber, V., Giranda, V.
登録日2012-06-28
公開日2012-08-22
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of the Urokinase
to be published
4FUC
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CRYSTAL STRUCTURE OF THE UROKINASE
分子名称:Urokinase-type plasminogen activator, 6-[(Z)-AMINO(IMINO)METHYL]-N-[4-(AMINOMETHYL)PHENYL]-2-NAPHTHAMIDE, SUCCINIC ACID, ...
著者Kang, Y.N., Stuckey, J.A., Nienaber, V., Giranda, V.
登録日2012-06-28
公開日2012-08-22
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Crystal Structure of the Urokinase
to be published
4FUD
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CRYSTAL STRUCTURE OF THE UROKINASE
分子名称:Urokinase-type plasminogen activator, 8-aminonaphthalene-2-carboximidamide, SUCCINIC ACID, ...
著者Kang, Y.N., Stuckey, J.A., Nienaber, V., Giranda, V.
登録日2012-06-28
公開日2012-08-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of the Urokinase
to be published
4FUE
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CRYSTAL STRUCTURE OF THE UROKINASE
分子名称:Urokinase-type plasminogen activator, 6-(1,2,3,4-tetrahydroisoquinolin-6-ylethynyl)naphthalene-2-carboximidamide, SUCCINIC ACID, ...
著者Kang, Y.N., Stuckey, J.A., Nienaber, V., Giranda, V.
登録日2012-06-28
公開日2012-08-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of the Urokinase
to be published
4FUF
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CRYSTAL STRUCTURE OF THE UROKINASE
分子名称:Urokinase-type plasminogen activator, 8-(3-bromopropoxy)-7-methoxynaphthalene-2-carboximidamide, SUCCINIC ACID, ...
著者Kang, Y.N., Stuckey, J.A., Nienaber, V., Giranda, V.
登録日2012-06-28
公開日2012-08-22
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of the Urokinase
to be published
4FUG
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CRYSTAL STRUCTURE OF THE UROKINASE
分子名称:Urokinase-type plasminogen activator, methyl (7-carbamimidoylnaphthalen-1-yl)carbamate, SULFATE ION, ...
著者Kang, Y.N., Stuckey, J.A., Nienaber, V., Giranda, V.
登録日2012-06-28
公開日2012-08-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of the Urokinase
to be published
4FUH
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CRYSTAL STRUCTURE OF THE UROKINASE
分子名称:Urokinase-type plasminogen activator, 6-[(phenylcarbamoyl)amino]naphthalene-2-carboximidamide, SULFATE ION, ...
著者Kang, Y.N., Stuckey, J.A., Nienaber, V., Giranda, V.
登録日2012-06-28
公開日2012-08-22
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal Structure of the Urokinase
to be published
4FUI
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CRYSTAL STRUCTURE OF THE UROKINASE
分子名称:Urokinase-type plasminogen activator, 7-METHOXY-8-[1-(METHYLSULFONYL)-1H-PYRAZOL-4-YL]NAPHTHALENE-2-CARBOXIMIDAMIDE, SULFATE ION, ...
著者Kang, Y.N., Stuckey, J.A., Nienaber, V., Giranda, V.
登録日2012-06-28
公開日2012-08-22
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of the Urokinase
to be published
4FUJ
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CRYSTAL STRUCTURE OF THE UROKINASE
分子名称:Urokinase-type plasminogen activator, 6-{(E)-2-[3-(2-hydroxyethyl)phenyl]ethenyl}naphthalene-2-carboximidamide, SUCCINIC ACID, ...
著者Kang, Y.N., Stuckey, J.A., Nienaber, V., Giranda, V.
登録日2012-06-28
公開日2012-08-22
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal Structure of the Urokinase
TO BE PUBLISHED
4LKQ
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CRYSTAL STRUCTURE OF PDE10A2 WITH FRAGMENT ZT017
分子名称:cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, 4-amino-1,7-dihydro-6H-pyrazolo[3,4-d]pyrimidine-6-thione, NICKEL (II) ION
著者Sridhar, V., Badger, J., Logan, C., Chie-Leon, B., Nienaber, V.
登録日2013-07-08
公開日2014-02-26
最終更新日2014-03-26
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Identification and Optimization of PDE10A Inhibitors Using Fragment-Based Screening by Nanocalorimetry and X-ray Crystallography.
J Biomol Screen, 19, 2014
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