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4NTF
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BU of 4ntf by Molmil
Mus Musculus LTC4 synthase in S-hexyl-GSH complex form
Descriptor: Leukotriene C4 synthase, NICKEL (II) ION, PALMITIC ACID, ...
Authors:Niegowski, D, Rinaldo-Matthis, A, Haeggstrom, J.Z.
Deposit date:2013-12-02
Release date:2015-01-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:To be published
To be Published
4NTA
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BU of 4nta by Molmil
Mus Musculus LTC4 synthase in apo form
Descriptor: Leukotriene C4 synthase, PALMITIC ACID, SULFATE ION
Authors:Niegowski, D, Rinaldo-Matthis, A, Haeggstrom, J.Z.
Deposit date:2013-12-02
Release date:2015-01-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Mus Musculus LTC4 synthase in apo form
To be Published
4NTB
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BU of 4ntb by Molmil
Mus Musculus LTC4 synthase in GSH complex form
Descriptor: GLUTATHIONE, Leukotriene C4 synthase, NICKEL (II) ION, ...
Authors:Niegowski, D, Rinaldo-Matthis, A, Haeggstrom, J.Z.
Deposit date:2013-12-02
Release date:2015-01-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Mus Musculus LTC4 synthase in GSH complex form
To be Published
4JC7
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BU of 4jc7 by Molmil
Human LTC4 synthase in complex with product analogs - implications for enzyme catalysis
Descriptor: Leukotriene C4 synthase, NICKEL (II) ION, PALMITIC ACID, ...
Authors:Niegowski, D, Rinaldo-Matthis, A, Haeggstrom, J.Z.
Deposit date:2013-02-21
Release date:2014-01-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structures of Leukotriene C4 Synthase in Complex with Product Analogs: IMPLICATIONS FOR THE ENZYME MECHANISM.
J.Biol.Chem., 289, 2014
4JRZ
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BU of 4jrz by Molmil
Human LTC4 synthase in complex with product analogs - implications for enzyme catalysis
Descriptor: Leukotriene C4 synthase, NICKEL (II) ION, PALMITIC ACID, ...
Authors:Niegowski, D, Rinaldo-Matthis, A, Haeggstrom, J.Z.
Deposit date:2013-03-22
Release date:2014-01-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structures of Leukotriene C4 Synthase in Complex with Product Analogs: IMPLICATIONS FOR THE ENZYME MECHANISM.
J.Biol.Chem., 289, 2014
4JCZ
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BU of 4jcz by Molmil
Human LTC4 synthase in complex with product analogs - implications for enzyme catalysis
Descriptor: Leukotriene C4 synthase, NICKEL (II) ION, PALMITIC ACID, ...
Authors:Niegowski, D, Rinaldo-Matthis, A, Haeggstrom, J.Z.
Deposit date:2013-02-22
Release date:2014-01-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal Structures of Leukotriene C4 Synthase in Complex with Product Analogs: IMPLICATIONS FOR THE ENZYME MECHANISM.
J.Biol.Chem., 289, 2014
4J7T
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BU of 4j7t by Molmil
Human LTC4 synthase in complex with product analogs - implications for enzyme catalysis
Descriptor: D-gamma-glutamyl-S-(4-phenylbutyl)-L-cysteinylglycine, Leukotriene C4 synthase, NICKEL (II) ION, ...
Authors:Niegowski, D, Rinaldo-Matthis, A, Haeggstrom, J.Z.
Deposit date:2013-02-14
Release date:2014-01-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.203 Å)
Cite:Crystal Structures of Leukotriene C4 Synthase in Complex with Product Analogs: IMPLICATIONS FOR THE ENZYME MECHANISM.
J.Biol.Chem., 289, 2014
4J7Y
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BU of 4j7y by Molmil
Human LTC4 synthase in complex with product analogs - implications for enzyme catalysis
Descriptor: D-gamma-glutamyl-(Z)-N-(carboxymethylidene)-S-[(2R)-2-hydroxy-4-phenylbutyl]-L-cysteinamide, Leukotriene C4 synthase, NICKEL (II) ION, ...
Authors:Niegowski, D, Rinaldo-Matthis, A, Haeggstrom, J.Z.
Deposit date:2013-02-14
Release date:2014-01-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.901 Å)
Cite:Crystal Structures of Leukotriene C4 Synthase in Complex with Product Analogs: IMPLICATIONS FOR THE ENZYME MECHANISM.
J.Biol.Chem., 289, 2014
3LEO
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BU of 3leo by Molmil
Structure of human Leukotriene C4 synthase mutant R31Q in complex with glutathione
Descriptor: DODECYL-BETA-D-MALTOSIDE, GLUTATHIONE, GLYCEROL, ...
Authors:Niegowski, D, Martinez-Molina, D, Rinaldo-Matthis, A, Nordlund, P, Haeggstrom, J.
Deposit date:2010-01-15
Release date:2010-10-27
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Arginine 104 is a key catalytic residue in leukotriene C4 synthase.
J.Biol.Chem., 285, 2010
3U9W
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BU of 3u9w by Molmil
Structure of human Leukotriene A4 hydrolase in complex with inhibitor sc57461A
Descriptor: ACETATE ION, CHLORIDE ION, GLYCEROL, ...
Authors:Niegowski, D, Thunnissen, M, Tholander, F, Rinaldo-Matthis, A, Muroya, A, Haeggstrom, J.Z.
Deposit date:2011-10-20
Release date:2012-10-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Structure of human Leukotriene A4 hydrolase in complex with inhibitor sc57461A
To be Published
2IUB
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BU of 2iub by Molmil
Crystal structure of a divalent metal ion transporter CorA at 2.9 A resolution.
Descriptor: CHLORIDE ION, DIVALENT CATION TRANSPORT-RELATED PROTEIN, MAGNESIUM ION
Authors:Eshaghi, S, Niegowski, D, Kohl, A, Martinez Molina, D, Lesley, S.A, Nordlund, P.
Deposit date:2006-06-01
Release date:2006-08-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structure of a Divalent Metal Ion Transporter Cora at 2.9 Angstrom Resolution.
Science, 313, 2006
2UUH
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BU of 2uuh by Molmil
Crystal structure of Human Leukotriene C4 Synthase in complex with substrate glutathione
Descriptor: DODECYL-ALPHA-D-MALTOSIDE, GLUTATHIONE, LEUKOTRIENE C4 SYNTHASE, ...
Authors:Martinez Molina, D, Wetterholm, A, Kohl, A, McCarthy, A.A, Niegowski, D, Ohlson, E, Hammarberg, T, Eshaghi, S, Haeggstrom, J.Z, Nordlund, P.
Deposit date:2007-03-02
Release date:2007-07-17
Last modified:2011-12-07
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural Basis for Synthesis of Inflammatory Mediators by Human Leukotriene C4 Synthase.
Nature, 448, 2007
2UUI
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BU of 2uui by Molmil
Crystal structure of Human Leukotriene C4 Synthase
Descriptor: DODECYL-BETA-D-MALTOSIDE, LEUKOTRIENE C4 SYNTHASE, NICKEL (II) ION, ...
Authors:Martinez Molina, D, Wetterholm, A, Kohl, A, McCarthy, A.A, Niegowski, D, Ohlson, E, Hammarberg, T, Eshaghi, S, Haeggstrom, J.Z, Nordlund, P.
Deposit date:2007-03-02
Release date:2007-07-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for Synthesis of Inflammatory Mediators by Human Leukotriene C4 Synthase.
Nature, 448, 2007
4GAA
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BU of 4gaa by Molmil
Structure of Leukotriene A4 hydrolase from Xenopus laevis complexed with inhibitor bestatin
Descriptor: 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, MGC78867 protein, ZINC ION
Authors:Stsiapanava, A, Kumar, R.B, Haeggstrom, J.Z, Rinaldo-Matthis, A.
Deposit date:2012-07-25
Release date:2013-06-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Product formation controlled by substrate dynamics in leukotriene A4 hydrolase.
Biochim.Biophys.Acta, 1844, 2014

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