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1SDN
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CRYSTAL STRUCTURE OF A DEACYLATION-DEFECTIVE MUTANT OF PENICILLIN-BINDING PROTEIN 5 MODIFIED BY MERCURY
Descriptor:Penicillin-binding protein 5, MERCURY (II) ION
Authors:Nicola, G., Nicholas, R.A., Davies, C.
Deposit date:2004-02-13
Release date:2005-02-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A large displacement of the SXN motif of Cys115-modified penicillin-binding protein 5 from Escherichia coli.
Biochem.J., 392, 2005
1NZU
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WILD-TYPE PENICILLIN-BINDING PROTEIN 5 FROM E. COLI MODIFIED BY BETA-MERCAPTOETHANOL
Descriptor:Penicillin-binding protein 5, BETA-MERCAPTOETHANOL
Authors:Nicola, G., Nicholas, R.A., Davies, C.
Deposit date:2003-02-19
Release date:2004-03-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:A large displacement of the SXN motif of Cys115-modified penicillin-binding protein 5 from Escherichia coli.
Biochem.J., 392, 2005
1Z6F
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CRYSTAL STRUCTURE OF PENICILLIN-BINDING PROTEIN 5 FROM E. COLI IN COMPLEX WITH A BORONIC ACID INHIBITOR
Descriptor:Penicillin-binding protein 5, N1-[(1R)-1-(DIHYDROXYBORYL)ETHYL]-N2-[(TERT-BUTOXYCARBONYL)-D-GAMMA-GLUTAMYL]-N6-[(BENZYLOXY)CARBONYL-L-LYSINAMIDE, GLYCEROL
Authors:Nicola, G., Peddi, S., Stefanova, M., Nicholas, R.A., Gutheil, W.G., Davies, C.
Deposit date:2005-03-22
Release date:2005-06-21
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal Structure of Escherichia coli Penicillin-Binding Protein 5 Bound to a Tripeptide Boronic Acid Inhibitor: A Role for Ser-110 in Deacylation.
Biochemistry, 44, 2005
3MZD
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STRUCTURE OF PENICILLIN-BINDING PROTEIN 5 FROM E. COLI: CLOXACILLIN ACYL-ENZYME COMPLEX
Descriptor:D-alanyl-D-alanine carboxypeptidase dacA, (2R,4S)-2-[(1S)-1-({[3-(2-chlorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, GLYCEROL
Authors:Nicola, G., Tomberg, J., Pratt, R.F., Nicholas, R.A., Davies, C.
Deposit date:2010-05-12
Release date:2011-03-16
Last modified:2011-08-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of covalent complexes of beta-lactam antibiotics with Escherichia coli penicillin-binding protein 5: toward an understanding of antibiotic specificity
Biochemistry, 49, 2010
3MZE
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STRUCTURE OF PENICILLIN-BINDING PROTEIN 5 FROM E.COLI: CEFOXITIN ACYL-ENZYME COMPLEX
Descriptor:D-alanyl-D-alanine carboxypeptidase dacA, (2R)-5-[(carbamoyloxy)methyl]-2-{(1S)-1-methoxy-2-oxo-1-[(thiophen-2-ylacetyl)amino]ethyl}-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, GLYCEROL
Authors:Nicola, G., Tomberg, J., Pratt, R.F., Nicholas, R.A., Davies, C.
Deposit date:2010-05-12
Release date:2011-03-16
Last modified:2018-09-12
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of covalent complexes of beta-lactam antibiotics with Escherichia coli penicillin-binding protein 5: toward an understanding of antibiotic specificity
Biochemistry, 49, 2010
3MZF
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STRUCTURE OF PENICILLIN-BINDING PROTEIN 5 FROM E. COLI: IMIPENEM ACYL-ENZYME COMPLEX
Descriptor:D-alanyl-D-alanine carboxypeptidase dacA, (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carboxylic acid, GLYCEROL
Authors:Nicola, G., Tomberg, J., Pratt, R.F., Nicholas, R.A., Davies, C.
Deposit date:2010-05-12
Release date:2011-03-16
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structures of covalent complexes of beta-lactam antibiotics with Escherichia coli penicillin-binding protein 5: toward an understanding of antibiotic specificity
Biochemistry, 49, 2010
1NJ4
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CRYSTAL STRUCTURE OF A DEACYLATION-DEFECTIVE MUTANT OF PENICILLIN-BINDING PROTEIN 5 AT 1.9 A RESOLUTION
Descriptor:Penicillin-binding protein 5
Authors:Nicola, G., Nicholas, R.A., Davies, C.
Deposit date:2002-12-30
Release date:2003-01-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of wild-type penicillin-binding protein 5 from Escherichia coli: implications for deacylation of the acyl-enzyme complex.
J.Biol.Chem., 278, 2003
1NZO
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THE CRYSTAL STRUCTURE OF WILD TYPE PENICILLIN-BINDING PROTEIN 5 FROM E. COLI
Descriptor:Penicillin-binding protein 5, BETA-MERCAPTOETHANOL
Authors:Nicholas, R.A., Krings, S., Tomberg, J., Nicola, G., Davies, C.
Deposit date:2003-02-19
Release date:2004-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of wild-type penicillin-binding protein 5 from Escherichia coli: implications for deacylation of the acyl-enzyme complex.
J.Biol.Chem., 278, 2003
2QBX
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EPHB2/SNEW ANTAGONISTIC PEPTIDE COMPLEX
Descriptor:Ephrin type-B receptor 2, antagonistic peptide, SULFATE ION
Authors:Chrencik, J.E., Brooun, A., Recht, M.I., Nicola, G., Pasquale, E.B., Kuhn, P., Accelerated Technologies Center for Gene to 3D Structure (ATCG3D)
Deposit date:2007-06-18
Release date:2007-11-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Three-dimensional structure of the EphB2 receptor in complex with an antagonistic peptide reveals a novel mode of inhibition.
J.Biol.Chem., 282, 2007
2JNF
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SOLUTION STRUCTURE OF FLY TROPONIN C, ISOFORM F1
Descriptor:Troponin C
Authors:De Nicola, G.F., Bullard, B., Pastore, A.
Deposit date:2007-01-18
Release date:2007-08-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The structure of lethocerus troponin C: insights into the mechanism of stretch activation in muscles
Structure, 15, 2007