Author results

5YNX
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STRUCTURE OF HOUSE DUST MITE ALLERGEN DER F 21 IN PEG400
Descriptor:Allergen Der f 21, PENTAETHYLENE GLYCOL, GLYCEROL, ...
Authors:Ng, C.L., Chew, F.T., Pang, S.L., Ho, K.L., Teh, A.H., Waterman, J., Rambo, R., Mathavan, I., Beis, K., Say, Y.H.
Deposit date:2017-10-25
Release date:2019-03-13
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Structure of house dust mite allergen Der f 21 in PEG400
To Be Published
5YNY
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STRUCTURE OF HOUSE DUST MITE ALLERGEN DER F 21 IN PEG2KMME
Descriptor:Allergen Der f 21
Authors:Ng, C.L., Chew, F.T., Pang, S.L., Ho, K.L., Teh, A.H., Waterman, J., Rambo, R., Mathavan, I.
Deposit date:2017-10-25
Release date:2019-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of house dust mite allergen Der F 21 in PEG2KMME
To Be Published
1W94
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CRYSTAL STRUCTURE OF MIL (MTH680), AN ARCHAEAL IMP4-LIKE PROTEIN
Descriptor:PROBABLE BRIX-DOMAIN RIBOSOMAL BIOGENESIS PROTEIN
Authors:Ng, C.L., Antson, A.A., Ortiz-Lombardia, M.
Deposit date:2004-10-06
Release date:2005-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Mil (Mth680): Internal Duplication and Similarity between the Imp4/Brix Domain and the Anticodon-Binding Domain of Class Iia Aminoacyl-tRNA Synthetases
Embo Rep., 6, 2005
2WBM
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CRYSTAL STRUCTURE OF MTHSBDS, THE HOMOLOGUE OF THE SHWACHMAN-BODIAN- DIAMOND SYNDROME PROTEIN IN THE EURIARCHAEON METHANOTHERMOBACTER THERMAUTOTROPHICUS
Descriptor:RIBOSOME MATURATION PROTEIN SDO1 HOMOLOG, GLYCEROL, SULFATE ION, ...
Authors:Ng, C.L., Isupov, M.N., Lebedev, A.A., Ortiz-Lombardia, M., Antson, A.A.
Deposit date:2009-03-02
Release date:2009-06-02
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Conformational Flexibility and Molecular Interactions of an Archaeal Homologue of the Shwachman-Bodian-Diamond Syndrome Protein.
Bmc Struct.Biol., 9, 2009
2WNR
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THE STRUCTURE OF METHANOTHERMOBACTER THERMAUTOTROPHICUS EXOSOME CORE ASSEMBLY
Descriptor:PROBABLE EXOSOME COMPLEX EXONUCLEASE 2, PROBABLE EXOSOME COMPLEX EXONUCLEASE 1, PHOSPHATE ION
Authors:Ng, C.L., Waterman, D.G., Antson, A.A., Ortiz-Lombardia, M.
Deposit date:2009-07-19
Release date:2010-04-28
Last modified:2012-05-30
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure of the Methanothermobacter Thermautotrophicus Exosome Rnase Ph Ring
Acta Crystallogr.,Sect.D, 66, 2010
2WNY
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STRUCTURE OF MTH689, A DUF54 PROTEIN FROM METHANOTHERMOBACTER THERMAUTOTROPHICUS
Descriptor:CONSERVED PROTEIN MTH689, NICKEL (II) ION, CHLORIDE ION
Authors:Ng, C.L., Waterman, D.G., Lebedev, A.A., Smits, C., Ortiz-Lombardia, M., Antson, A.A.
Deposit date:2009-07-21
Release date:2010-09-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure of Mth689, a Duf54 Protein from Methanothermobacter Thermautotrophicus
To be Published
4V5K
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STRUCTURE OF CYTOTOXIC DOMAIN OF COLICIN E3 BOUND TO THE 70S RIBOSOME
Descriptor:16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Ng, C.L., Lang, K., Meenan, N.A.G., Sharma, A., Kelley, A.C., Kleanthous, C., Ramakrishnan, V.
Deposit date:2010-05-29
Release date:2014-07-09
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural Basis for 16S Ribosomal RNA Cleavage by the Cytotoxic Domain of Colicin E3.
Nat.Struct.Mol.Biol., 17, 2010
5A2A
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CRYSTAL STRUCTURE OF ANOXYBACILLUS ALPHA-AMYLASE PROVIDES INSIGHTS INTO A NEW GLYCOSYL HYDROLASE SUBCLASS
Descriptor:APO FORM OF ANOXYBACILLUS ALPHA-AMYLASES, ACETATE ION, CALCIUM ION
Authors:Ng, C.L., Chai, K.P., Othman, N.F., Teh, A.H., Ho, K.L., Chan, K.G., Goh, K.M.
Deposit date:2015-05-16
Release date:2016-03-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of Anoxybacillus Alpha-Amylase Provides Insights Into Maltose Binding of a New Glycosyl Hydrolase Subclass.
Sci.Rep., 6, 2016
5A2B
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CRYSTAL STRUCTURE OF ANOXYBACILLUS ALPHA-AMYLASE PROVIDES INSIGHTS INTO A NEW GLYCOSYL HYDROLASE SUBCLASS
Descriptor:ANOXYBACILLUS ALPHA-AMYLASE, MALTOSE, CALCIUM ION
Authors:Ng, C.L., Chai, K.P., Othman, N.F., Teh, A.H., Ho, K.L., Chan, K.G., Goh, K.M.
Deposit date:2015-05-17
Release date:2016-03-30
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal Structure of Anoxybacillus Alpha-Amylase Provides Insights Into Maltose Binding of a New Glycosyl Hydrolase Subclass.
Sci.Rep., 6, 2016
5A2C
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CRYSTAL STRUCTURE OF ANOXYBACILLUS ALPHA-AMYLASE PROVIDES INSIGHTS INTO A NEW GLYCOSYL HYDROLASE SUBCLASS
Descriptor:ALPHA-AMYLASE, MALTOSE, CALCIUM ION
Authors:Ng, C.L., Chai, K.P., Othman, N.F., Teh, A.H., Ho, K.L., Chan, K.G., Goh, K.M.
Deposit date:2015-05-17
Release date:2016-03-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of Anoxybacillus Alpha-Amylase Provides Insights Into Maltose Binding of a New Glycosyl Hydrolase Subclass.
Sci.Rep., 6, 2016
5ZRT
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CRYSTAL STRUCTURE OF HUMAN C1ORF123 PROTEIN
Descriptor:UPF0587 protein C1orf123, GLYCEROL, CHLORIDE ION, ...
Authors:Rahaman, S.N.A., Yusop, J.M., Mohamed-Hussein, Z.Z., Wan Mohd, A., Ho, K.L., Teh, A.H., Waterman, J., Ng, C.L.
Deposit date:2018-04-25
Release date:2018-08-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The crystal structure of human C1ORF123 reveals internal symmetry and a zinc-binding domain of the eukaryotic conserved DUF866 family protein
Peerj, 2018
2YCB
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STRUCTURE OF THE ARCHAEAL BETA-CASP PROTEIN WITH N-TERMINAL KH DOMAINS FROM METHANOTHERMOBACTER THERMAUTOTROPHICUS
Descriptor:CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR, ZINC ION, PHOSPHATE ION, ...
Authors:Silva, A.P.G., Chechik, M., Byrne, R.T., Waterman, D.G., Ng, C.L., Dodson, E.J., Koonin, E.V., Antson, A.A., Smits, C.
Deposit date:2011-03-13
Release date:2011-05-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure and Activity of a Novel Archaeal Beta-Casp Protein with N-Terminal Kh Domains.
Structure, 19, 2011
4AQY
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STRUCTURE OF RIBOSOME-APRAMYCIN COMPLEXES
Descriptor:16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Matt, T., Ng, C.L., Lang, K., Sha, S.H., Akbergenov, R., Shcherbakov, D., Meyer, M., Duscha, S., Xie, J., Dubbaka, S.R., Perez-Fernandez, D., Vasella, A., Ramakrishnan, V., Schacht, J., Bottger, E.C.
Deposit date:2012-04-20
Release date:2012-07-18
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Dissociation of Antibacterial Activity and Aminoglycoside Ototoxicity in the 4-Monosubstituted 2-Deoxystreptamine Apramycin.
Proc.Natl.Acad.Sci.USA, 109, 2012
4JV5
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CRYSTAL STRUCTURES OF PSEUDOURIDINILATED STOP CODONS WITH ASLS
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Fernandez, I.S., Ng, C.L., Kelley, A.C., Guowei, W., Yu, Y.T., Ramakrishnan, V.
Deposit date:2013-03-25
Release date:2013-06-26
Last modified:2013-08-21
Method:X-RAY DIFFRACTION (3.162 Å)
Cite:Unusual base pairing during the decoding of a stop codon by the ribosome.
Nature, 500, 2013
4JYA
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CRYSTAL STRUCTURES OF PSEUDOURIDINILATED STOP CODONS WITH ASLS
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Fernandez, I.S., Ng, C.L., Kelley, A.C., Guowei, W., Yu, Y.T., Ramakrishnan, V.
Deposit date:2013-03-29
Release date:2013-06-26
Last modified:2013-08-21
Method:X-RAY DIFFRACTION (3.098 Å)
Cite:Unusual base pairing during the decoding of a stop codon by the ribosome.
Nature, 500, 2013
4K0K
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CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT COMPLEXED WITH A SERINE-ASL AND MRNA CONTAINING A STOP CODON
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Fernandez, I.S., Ng, C.L., Kelley, A.C., Guowei, W., Yu, Y.T., Ramakrishnan, V.
Deposit date:2013-04-04
Release date:2013-06-26
Last modified:2013-08-21
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Unusual base pairing during the decoding of a stop codon by the ribosome.
Nature, 500, 2013
4V9I
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CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS 70S IN COMPLEX WITH TRNAS AND MRNA CONTAINING A PSEUDOURIDINE IN A STOP CODON
Descriptor:16S ribosomal RNA, 30S Ribosomal protein S2, 30S Ribosomal protein S3, ...
Authors:Fernandez, I.S., Ng, C.L., Kelley, A.C., Guowei, W., Yu, Y.T., Ramakrishnan, V.
Deposit date:2013-04-04
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Unusual base pairing during the decoding of a stop codon by the ribosome.
Nature, 500, 2013
5BT2
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MECP2 MBD DOMAIN (A140V) IN COMPLEX WITH METHYLATED DNA
Descriptor:Methyl-CpG-binding protein 2, DNA (5'-D(*TP*CP*TP*GP*GP*AP*AP*(5CM)P*GP*GP*AP*AP*TP*TP*CP*TP*TP*CP*TP*A)-3'), DNA (5'-D(*AP*TP*AP*GP*AP*AP*GP*AP*AP*TP*TP*CP*(5CM)P*GP*TP*TP*CP*CP*AP*G)-3')
Authors:Ho, K.L., Chia, J.Y., Tan, W.S., Ng, C.L., Hu, N.J., Foo, H.L.
Deposit date:2015-06-02
Release date:2016-08-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A/T Run Geometry of B-form DNA Is Independent of Bound Methyl-CpG Binding Domain, Cytosine Methylation and Flanking Sequence
Sci Rep, 6, 2016
5Z0C
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NEROL DEHYDROGENASE FROM PERSICARIA MINOR
Descriptor:Nerol dehydrogenase, ZINC ION, GLYCEROL, ...
Authors:Tan, C.S., Ng, C.L., Zainal, Z.
Deposit date:2017-12-19
Release date:2018-01-17
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Structural and kinetic studies of a novel nerol dehydrogenase from Persicaria minor, a nerol-specific enzyme for citral biosynthesis.
Plant Physiol. Biochem., 123, 2017
4B3M
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CRYSTAL STRUCTURE OF THE 30S RIBOSOME IN COMPLEX WITH COMPOUND 1
Descriptor:16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Ng, C.L., Lang, K., Shcherbakov, D., Matt, T., Perez-Fernandez, D., Patak, R., Meyer, M., Duscha, S., Akbergenov, R., Boukari, H., Freihofer, P., Kudyba, I., Reddy, M.S.K., Nandurikar, R.S., Ramakrishnan, V., Vasella, A., Bottger, E.C.
Deposit date:2012-07-25
Release date:2013-08-07
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:4'-O-Substitutions Determine Selectivity of Aminoglycoside Antibiotics
Nat.Commun., 5, 2014
4B3R
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CRYSTAL STRUCTURE OF THE 30S RIBOSOME IN COMPLEX WITH COMPOUND 30
Descriptor:16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Ng, C.L., Lang, K., Shcherbakov, D., Matt, T., Perez-Fernandez, D., Patak, R., Meyer, M., Duscha, S., Akbergenov, R., Boukari, H., Freihofer, P., Kudyba, I., Reddy, M.S.K., Nandurikar, R.S., Ramakrishnan, V., Vasella, A., Bottger, E.C.
Deposit date:2012-07-26
Release date:2013-08-07
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:4'-O-Substitutions Determine Selectivity of Aminoglycoside Antibiotics
Nat.Commun., 5, 2014
4B3S
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CRYSTAL STRUCTURE OF THE 30S RIBOSOME IN COMPLEX WITH COMPOUND 37
Descriptor:16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Ng, C.L., Lang, K., Shcherbakov, D., Matt, T., Perez-Fernandez, D., Patak, R., Meyer, M., Duscha, S., Akbergenov, R., Boukari, H., Freihofer, P., Kudyba, I., Reddy, M.S.K., Nandurikar, R.S., Ramakrishnan, V., Vasella, A., Bottger, E.C.
Deposit date:2012-07-26
Release date:2013-08-07
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:4'-O-Substitutions Determine Selectivity of Aminoglycoside Antibiotics
Nat.Commun., 5, 2014
4B3T
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CRYSTAL STRUCTURE OF THE 30S RIBOSOME IN COMPLEX WITH COMPOUND 39
Descriptor:16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Ng, C.L., Lang, K., Shcherbakov, D., Matt, T., Perez-Fernandez, D., Patak, R., Meyer, M., Duscha, S., Akbergenov, R., Boukari, H., Freihofer, P., Kudyba, I., Reddy, M.S.K., Nandurikar, R.S., Ramakrishnan, V., Vasella, A., Bottger, E.C.
Deposit date:2012-07-26
Release date:2013-08-07
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:4'-O-Substitutions Determine Selectivity of Aminoglycoside Antibiotics
Nat.Commun., 5, 2014
4RX0
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CRYSTAL STRUCTURE OF PLASMODIUM FALCIPARUM DIHYDROOROTATE DEHYDROGENASE BOUND WITH INHIBITOR DSM265
Descriptor:Dihydroorotate dehydrogenase (quinone), mitochondrial, 2-(1,1-difluoroethyl)-5-methyl-N-[4-(pentafluoro-lambda~6~-sulfanyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine, ...
Authors:Deng, X., Phillips, M., Tomchick, D.
Deposit date:2014-12-08
Release date:2015-07-29
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria.
Sci Transl Med, 7, 2015
5BOO
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CRYSTAL STRUCTURE OF PLASMODIUM FALCIPARUM DIHYDROOROTATE DEHYDROGENASE BOUND WITH INHIBITOR DSM265
Descriptor:Dihydroorotate dehydrogenase (quinone), mitochondrial, 2-(1,1-difluoroethyl)-5-methyl-N-[4-(pentafluoro-lambda~6~-sulfanyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine, ...
Authors:Phillips, M., Deng, X., Tomchick, D.
Deposit date:2015-05-27
Release date:2015-07-29
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria.
Sci Transl Med, 7, 2015
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