Author results

3BUM
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CRYSTAL STRUCTURE OF C-CBL-TKB DOMAIN COMPLEXED WITH ITS BINDING MOTIF IN SPROUTY2
分子名称:Portein sprouty homolog 2, E3 ubiquitin-protein ligase CBL
著者Ng, C., Jackson, A.R., Buschdorf, P.J., Sun, Q., Guy, R.G., Sivaraman, J.
登録日2008-01-03
公開日2008-02-26
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates
Embo J., 27, 2008
3BUN
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CRYSTAL STRUCTURE OF C-CBL-TKB DOMAIN COMPLEXED WITH ITS BINDING MOTIF IN SPROUTY4
分子名称:13-meric peptide from Portein sprouty homolog 4, E3 ubiquitin-protein ligase CBL
著者Ng, C., Jackson, R.A., Buschdorf, J.P., Sun, Q., Guy, G.R., Sivaraman, J.
登録日2008-01-03
公開日2008-02-26
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates
Embo J., 27, 2008
3BUO
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CRYSTAL STRUCTURE OF C-CBL-TKB DOMAIN COMPLEXED WITH ITS BINDING MOTIF IN EGF RECEPTOR'
分子名称:13-meric peptide from Epidermal growth factor receptor, E3 ubiquitin-protein ligase CBL
著者Ng, C., Jackson, R.A., Buschdorf, J.P., Sun, Q., Guy, G.R., Sivaraman, J.
登録日2008-01-03
公開日2008-02-26
最終更新日2018-09-19
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates
Embo J., 27, 2008
3BUW
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CRYSTAL STRUCTURE OF C-CBL-TKB DOMAIN COMPLEXED WITH ITS BINDING MOTIF IN SYK
分子名称:13-meric peptide from Tyrosine-protein kinase SYK, E3 ubiquitin-protein ligase CBL
著者Ng, C., Jackson, R.A., Buschdorf, J.P., Sun, Q., Guy, G.R., Sivaraman, J.
登録日2008-01-03
公開日2008-02-26
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates
Embo J., 27, 2008
3BUX
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CRYSTAL STRUCTURE OF C-CBL-TKB DOMAIN COMPLEXED WITH ITS BINDING MOTIF IN C-MET
分子名称:13-meric peptide from Hepatocyte growth factor receptor, E3 ubiquitin-protein ligase CBL
著者Ng, C., Jackson, R.A., Buschdorf, J.P., Sun, Q., Guy, G.R., Sivaraman, J.
登録日2008-01-03
公開日2008-02-26
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates
Embo J., 27, 2008
3HJ6
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STRUCTURE OF HALOTHERMOTHRIX ORENII FRUCTOKINASE (FRK)
分子名称:Fructokinase
著者Chua, T.K., Seetharaman, J., Kasprzak, J.M., Ng, C., Patel, B.K., Love, C., Bujnicki, J.M., Sivaraman, J.
登録日2009-05-21
公開日2010-06-09
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of a fructokinase homolog from Halothermothrix orenii
J.Struct.Biol., 171, 2010
3EM6
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CRYSTAL STRUCTURE OF I50L/A71V MUTANT OF HIV-1 PROTEASE IN COMPLEX WITH INHIBITOR DARUNAVIR
分子名称:Protease, (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, PHOSPHATE ION, ...
著者Royer, C.J., King, N.M., Prabu-Jeyabalan, M., Ng, C., Nalivaika, E.A., Schiffer, C.A.
登録日2008-09-23
公開日2009-09-01
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Kinetic and structural studies on atazanavir specific I50L drug-resistant HIV-1 protease mutant.
To be Published
1A1W
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FADD DEATH EFFECTOR DOMAIN, F25Y MUTANT, NMR MINIMIZED AVERAGE STRUCTURE
分子名称:FADD PROTEIN
著者Eberstadt, M., Huang, B., Chen, Z., Meadows, R.P., Ng, C., Fesik, S.W.
登録日1997-12-18
公開日1998-12-30
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献NMR structure and mutagenesis of the FADD (Mort1) death-effector domain.
Nature, 392, 1998
1A1Z
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FADD DEATH EFFECTOR DOMAIN, F25G MUTANT, NMR MINIMIZED AVERAGE STRUCTURE
分子名称:FADD PROTEIN
著者Eberstadt, M., Huang, B., Chen, Z., Meadows, R.P., Ng, C., Fesik, S.W.
登録日1997-12-18
公開日1998-12-30
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献NMR structure and mutagenesis of the FADD (Mort1) death-effector domain.
Nature, 392, 1998
4K7P
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GENERATION AND CHARACTERIZATION OF A UNIQUE REAGENT THAT RECOGNIZES A PANEL OF RECOMBINANT HUMAN MONOCLONAL ANTIBODY THERAPEUTICS IN THE PRESENCE OF ENDOGENOUS HUMAN IGG
分子名称:antibody rhumAb6 Fab fragment light chain, antibody rhumAb6 Fab fragment heavy chain, antibody 10C4 Fab fragment heavy chain, ...
著者Eigenbrot, C., Shia, S.
登録日2013-04-17
公開日2013-08-07
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Generation and characterization of a unique reagent that recognizes a panel of recombinant human monoclonal antibody therapeutics in the presence of endogenous human IgG.
MAbs, 5, 2013
3OB1
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CRYSTAL STRUCTURE OF C-CBL TKB DOMAIN IN COMPLEX WITH DOUBLE PHOSPHORYLATED SPRY2 PEPTIDE
分子名称:12-meric peptide from Protein sprouty homolog 2, E3 ubiquitin-protein ligase CBL
著者Sun, Q., Sivaraman, J.
登録日2010-08-06
公開日2010-08-18
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Additional serine/threonine phosphorylation reduces binding affinity but preserves interface topography of substrate proteins to the c-Cbl TKB domain
Plos One, 5, 2010
3OB2
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CRYSTAL STRUCTURE OF C-CBL TKB DOMAIN IN COMPLEX WITH DOUBLE PHOSPHORYLATED EGFR PEPTIDE
分子名称:12-meric peptide from Epidermal growth factor receptor, E3 ubiquitin-protein ligase CBL
著者Sun, Q., Sivaraman, J.
登録日2010-08-06
公開日2010-08-18
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Additional serine/threonine phosphorylation reduces binding affinity but preserves interface topography of substrate proteins to the c-Cbl TKB domain
Plos One, 5, 2010
3PLF
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REVERSE BINDING MODE OF METRD PEPTIDE COMPLEXED WITH C-CBL TKB DOMAIN
分子名称:MetRD peptide, E3 ubiquitin-protein ligase CBL, CALCIUM ION, ...
著者Sun, Q., Sivaraman, J.
登録日2010-11-15
公開日2010-12-01
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献An adjacent arginine, and the phosphorylated tyrosine in the c-Met receptor target sequence, dictates the orientation of c-Cbl binding
Febs Lett., 585, 2011
3VK6
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CRYSTAL STRUCTURE OF A PHOSPHOTYROSINE BINDING DOMAIN
分子名称:E3 ubiquitin-protein ligase Hakai, ZINC ION
著者Sivaraman, J., Mukherjee, M.
登録日2011-11-09
公開日2012-01-25
最終更新日2013-07-24
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of a novel phosphotyrosine-binding domain in Hakai that targets E-cadherin
Embo J., 31, 2012