Author results

5ABT
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S.ENTERICA HISA MUTANT D7N, G102A, V106M, D176A
Descriptor:1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO) METHYLIDENE AMINO] IMIDAZOLE-4-CARBOXAMIDE ISOMERASE, [(2R,3S,4R,5R)-5-[4-aminocarbonyl-5-[(E)-[[(2R,3R,4S,5R)-3,4-bis(oxidanyl)-5-(phosphonooxymethyl)oxolan-2-yl]amino]methylideneamino]imidazol-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate
Authors:Guo, X., Soderholm, A., Newton, M., Nasvall, J., Andersson, D., Patrick, W., Selmer, M.
Deposit date:2015-08-08
Release date:2016-09-28
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The Protein Structures, Functions and Dynamics of Adaptive Evolution
To be Published
5AC6
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S.ENTERICA HISA MUTANT D10G, DUP13-15, Q24L, G102A
Descriptor:SULFATE ION
Authors:Guo, X., Soderholm, A., Newton, M., Nasvall, J., Andersson, D., Patrick, W., Selmer, M.
Deposit date:2015-08-12
Release date:2016-09-28
Method:X-RAY DIFFRACTION (1.993 Å)
Cite:The Protein Structures, Functions and Dynamics of Adaptive Evolution
To be Published
1GN3
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H145Q MUTANT OF MYCOBACTERIUM TUBERCULOSIS IRON-SUPEROXIDE DISMUTASE.
Descriptor:SUPEROXIDE DISMUTASE, FE (III) ION
Authors:Bunting, K.A., Cooper, J.B., Badasso, M.O., Tickle, I.J., Newton, M., Wood, S.P., Zhang, Y., Young, D.B.
Deposit date:2001-10-02
Release date:2001-10-05
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (4 Å)
Cite:Engineering a Change in the Metal-Ion Specificity of the Iron-Depedent Superoxide Dismutase from Mycobacterium Tuberculosis. X-Ray Structure Analysis of Site-Directed Mutants.
Eur.J.Biochem., 251, 1998
1GN4
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H145E MUTANT OF MYCOBACTERIUM TUBERCULOSIS IRON-SUPEROXIDE DISMUTASE.
Descriptor:SUPEROXIDE DISMUTASE, MANGANESE (II) ION
Authors:Bunting, K.A., Cooper, J.B., Badasso, M.O., Tickle, I.J., Newton, M., Wood, S.P., Zhang, Y., Young, D.B.
Deposit date:2001-10-02
Release date:2001-10-05
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Engineering a Change in the Metal-Ion Specificity of the Iron-Depedent Superoxide Dismutase from Mycobacterium Tuberculosis. X-Ray Structure Analysis of Site-Directed Mutants
Eur.J.Biochem., 251, 1998
5AC7
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S. ENTERICA HISA WITH MUTATIONS D7N, D10G, DUP13-15
Descriptor:GLYCEROL, SODIUM ION, SULFATE ION
Authors:Newton, M., Guo, X., Soderholm, A., Nasvall, J., Andersson, D., Patrick, W., Selmer, M.
Deposit date:2015-08-12
Release date:2016-09-28
Last modified:2017-05-10
Method:X-RAY DIFFRACTION (1.904 Å)
Cite:Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5AC8
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S. ENTERICA HISA WITH MUTATIONS D10G, DUP13-15, G102A
Descriptor:SULFATE ION
Authors:Newton, M., Guo, X., Soderholm, A., Nasvall, J., Andersson, D., Patrick, W., Selmer, M.
Deposit date:2015-08-12
Release date:2016-09-28
Last modified:2017-05-10
Method:X-RAY DIFFRACTION (1.699 Å)
Cite:Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5G2H
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S. ENTERICA HISA WITH MUTATION L169R
Descriptor:SULFATE ION, GLYCEROL, SODIUM ION
Authors:Newton, M., Guo, X., Soderholm, A., Nasvall, J., Duarte, F., Andersson, D., Patrick, W., Selmer, M.
Deposit date:2016-04-08
Release date:2017-04-19
Last modified:2017-05-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5AB3
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S.ENTERICA HISA MUTANT D7N, D10G, DUP13-15, Q24L, G102A
Descriptor:1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, [(2R,3S,4R,5R)-5-[4-AMINOCARBONYL-5-[[(Z)-[(3R,4R)-3,4-DIHYDROXY-2-OXO-5-PHOSPHONOOXY-PENTYL]IMINOMETHYL]AMINO]IMIDAZOL-1-YL]-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL DIHYDROGEN PHOSPHATE, SODIUM ION
Authors:Guo, X., Soderholm, A., Newton, M., Nasvall, J., Andersson, D., Patrick, W., Selmer, M.
Deposit date:2015-07-31
Release date:2016-09-28
Last modified:2018-06-06
Method:X-RAY DIFFRACTION (1.803 Å)
Cite:Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5G1T
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S. ENTERICA HISA MUTANT DUP13-15, D10G
Descriptor:PHOSPHATE ION, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
Authors:Guo, X., Soderholm, A., Newton, M., Nasvall, J., Andersson, D., Patrick, W., Selmer, M.
Deposit date:2016-03-30
Release date:2017-04-19
Last modified:2017-05-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5G1Y
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S. ENTERICA HISA MUTANT D10G, DUP13-15,V14:2M, Q24L, G102
Descriptor:SULFATE ION, GLYCEROL
Authors:Guo, X., Soderholm, A., Newton, M., Nasvall, J., Andersson, D., Patrick, W., Selmer, M.
Deposit date:2016-04-01
Release date:2017-04-12
Last modified:2017-05-10
Method:X-RAY DIFFRACTION (1.798 Å)
Cite:Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5G2I
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S. ENTERICA HISA MUTANT DUP13-15(VVR)
Descriptor:PHOSPHATE ION, SODIUM ION
Authors:Guo, X., Soderholm, A., Newton, M., Nasvall, J., Duarte, F., Andersson, D., Patrick, W., Selmer, M.
Deposit date:2016-04-08
Release date:2017-04-19
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.601 Å)
Cite:Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5G2W
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S. ENTERICA HISA MUTANT D10G, G102A
Descriptor:SULFATE ION
Authors:Guo, X., Soderholm, A., Newton, M., Nasvall, J., Andersson, D., Patrick, W., Selmer, M.
Deposit date:2016-04-14
Release date:2017-04-19
Last modified:2017-05-10
Method:X-RAY DIFFRACTION (2.099 Å)
Cite:Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5G4E
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S. ENTERICA HISA MUTANT D10G, DUP13-15, Q24L, G102A, V106L
Descriptor:SULFATE ION, SODIUM ION, ACETIC ACID, ...
Authors:Soderholm, A., Guo, X., Newton, M., Nasvall, J., Duarte, F., Andersson, D., Patrick, W., Selmer, M.
Deposit date:2016-05-12
Release date:2017-04-19
Last modified:2017-05-10
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5G4W
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S. ENTERICA HISA MUTANT D7N, D10G, DUP13-15 (VVR) WITH SUBSTRATE PROFAR
Descriptor:HISA, [(2R,3S,4R,5R)-5-[4-aminocarbonyl-5-[(E)-[[(2R,3R,4S,5R)-3,4-bis(oxidanyl)-5-(phosphonooxymethyl)oxolan-2-yl]amino]methylideneamino]imidazol-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate, GLYCEROL
Authors:Guo, X., Soderholm, A., Newton, M., Nasvall, J., Duarte, F., Andersson, D., Patrick, W., Selmer, M.
Deposit date:2016-05-17
Release date:2017-04-19
Last modified:2017-05-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5G5I
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S. ENTERICA HISA MUTANT D10G
Descriptor:PHOSPHATE ION, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
Authors:Guo, X., Soderholm, A., Newton, M., Nasvall, J., Andersson, D., Patrick, W., Selmer, M.
Deposit date:2016-05-25
Release date:2017-04-19
Last modified:2017-05-10
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1EA5
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NATIVE ACETYLCHOLINESTERASE (E.C. 3.1.1.7) FROM TORPEDO CALIFORNICA AT 1.8A RESOLUTION
Descriptor:ACETYLCHOLINESTERASE, N-ACETYL-D-GLUCOSAMINE
Authors:Harel, M., Weik, M., Silman, I., Sussman, J.L.
Deposit date:2000-11-06
Release date:2000-11-08
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-Ray Structures of Torpedo Californica Acetylcholinesterase Complexed with (+)-Huperzine a and (-)-Huperzine B: Structural Evidence for an Active Site Rearrangement
Biochemistry, 41, 2002
2ACE
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NATIVE ACETYLCHOLINESTERASE (E.C. 3.1.1.7) FROM TORPEDO CALIFORNICA
Descriptor:ACETYLCHOLINESTERASE, ACETYLCHOLINE
Authors:Harel, M., Raves, M.L., Silman, I., Sussman, J.L.
Deposit date:1996-06-23
Release date:1996-11-08
Last modified:2016-06-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of acetylcholinesterase complexed with the nootropic alkaloid, (-)-huperzine A.
Nat.Struct.Biol., 4, 1997
1GN2
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S123C MUTANT OF THE IRON-SUPEROXIDE DISMUTASE FROM MYCOBACTERIUM TUBERCULOSIS.
Descriptor:SUPEROXIDE DISMUTASE, FE (III) ION
Authors:Bunting, K.A., Cooper, J.B., Tickle, I.J., Young, D.B.
Deposit date:2001-10-02
Release date:2001-10-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Engineering of an Intersubunit Disulfide Bridge in the Iron-Superoxide Dismutase of Mycobacterium Tuberculosis.
Arch.Biochem.Biophys., 397, 2002