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1BXL
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STRUCTURE OF BCL-XL/BAK PEPTIDE COMPLEX, NMR, MINIMIZED AVERAGE STRUCTURE
分子名称:BCL-XL, BAK PEPTIDE
著者Sattler, M., Liang, H., Nettesheim, D., Meadows, R.P., Harlan, J.E., Eberstadt, M., Yoon, H., Shuker, S.B., Chang, B.S., Minn, A.J., Thompson, C.B., Fesik, S.W.
登録日1996-10-16
公開日1997-10-29
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis.
Science, 275, 1997
1LXL
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NMR STRUCTURE OF BCL-XL, AN INHIBITOR OF PROGRAMMED CELL DEATH, MINIMIZED AVERAGE STRUCTURE
分子名称:BCL-XL
著者Muchmore, S.W., Sattler, M., Liang, H., Meadows, R.P., Harlan, J.E., Yoon, H.S., Nettesheim, D., Chang, B.S., Thompson, C.B., Wong, S.L., Ng, S.C., Fesik, S.W.
登録日1996-04-04
公開日1997-04-21
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death.
Nature, 381, 1996
1MAZ
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X-RAY STRUCTURE OF BCL-XL, AN INHIBITOR OF PROGRAMMED CELL DEATH
分子名称:Bcl-2-like protein 1
著者Muchmore, S.W., Sattler, M., Liang, H., Meadows, R.P., Harlan, J.E., Yoon, H.S., Nettesheim, D., Chang, B.S., Thompson, C.B., Wong, S.L., Ng, S.C., Fesik, S.W.
登録日1996-04-09
公開日1997-04-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death.
Nature, 381, 1996
1XOX
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SOLUTION STRUCTURE OF HUMAN SURVIVIN
分子名称:Apoptosis inhibitor survivin, ZINC ION
著者Sun, C., Nettesheim, D., Liu, Z., Olejniczak, E.T.
登録日2004-10-07
公開日2005-01-18
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure of human survivin and its binding interface with smac/diablo
Biochemistry, 44, 2005
2ABO
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NMR STRUCTURE OF GAMMA HERPESVIRUS 68 A VIRAL BCL-2 HOMOLOG
分子名称:bcl-2 homolog
著者Loh, J., Huang, Q., Petros, A.M., Nettesheim, D., van Dyk, L.F., Labrada, L., Speck, S.H., Levine, B., Olejniczak, E.T., Virgin, H.W.
登録日2005-07-15
公開日2006-05-16
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献A surface groove essential for viral Bcl-2 function during chronic infection in vivo.
Plos Pathog., 1, 2005
1FV9
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CRYSTAL STRUCTURE OF HUMAN MICROUROKINASE IN COMPLEX WITH 2-AMINO-5-HYDROXY-BENZIMIDAZOLE
分子名称:UROKINASE, SULFATE ION, 2-AMINO-5-HYDROXY-BENZIMIDAZOLE
著者Nienaber, V.
登録日2000-09-19
公開日2000-10-18
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Identification of novel inhibitors of urokinase via NMR-based screening.
J.Med.Chem., 43, 2000
1YW7
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H-METAP2 COMPLEXED WITH A444148
分子名称:Methionine aminopeptidase 2, MANGANESE (II) ION, 5-METHYL-2-[(PHENYLSULFONYL)AMINO]BENZOIC ACID
著者Park, C.H.
登録日2005-02-17
公開日2006-02-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Discovery and optimization of anthranilic acid sulfonamides as inhibitors of methionine aminopeptidase-2: a structural basis for the reduction of albumin binding.
J.Med.Chem., 49, 2006
1YW8
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H-METAP2 COMPLEXED WITH A751277
分子名称:Methionine aminopeptidase 2, MANGANESE (II) ION, 2-[(PHENYLSULFONYL)AMINO]-5,6,7,8-TETRAHYDRONAPHTHALENE-1-CARBOXYLIC ACID
著者Park, C.H.
登録日2005-02-17
公開日2006-02-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Discovery and optimization of anthranilic acid sulfonamides as inhibitors of methionine aminopeptidase-2: a structural basis for the reduction of albumin binding.
J.Med.Chem., 49, 2006
1YW9
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H-METAP2 COMPLEXED WITH A849519
分子名称:Methionine aminopeptidase 2, MANGANESE (II) ION, 2-[({2-[(1Z)-3-(DIMETHYLAMINO)PROP-1-ENYL]-4-FLUOROPHENYL}SULFONYL)AMINO]-5,6,7,8-TETRAHYDRONAPHTHALENE-1-CARBOXYLIC ACID
著者Park, C.H.
登録日2005-02-17
公開日2006-02-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Discovery and optimization of anthranilic acid sulfonamides as inhibitors of methionine aminopeptidase-2: a structural basis for the reduction of albumin binding.
J.Med.Chem., 49, 2006
1CYA
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NMR STUDIES OF (U-13C)CYCLOSPORIN A BOUND TO CYCLOPHILIN: BOUND CONFORMATION AND PORTIONS OF CYCLOSPORIN INVOLVED IN BINDING
分子名称:CYCLOSPORIN A
著者Fesik, S.W.
登録日1992-02-24
公開日1994-01-31
最終更新日2012-12-12
実験手法SOLUTION NMR
主引用文献NMR Studies of [U-13C]Cyclosporin a Bound to Cyclophilin: Bound Conformation and Portions of Cyclosporin Involved in Binding.
Biochemistry, 30, 1991
1CYB
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NMR STUDIES OF (U-13C)CYCLOSPORIN A BOUND TO CYCLOPHILIN: BOUND CONFORMATION AND PORTIONS OF CYCLOSPORIN INVOLVED IN BINDING
分子名称:CYCLOSPORIN A
著者Fesik, S.W.
登録日1992-02-24
公開日1994-01-31
最終更新日2012-12-12
実験手法SOLUTION NMR
主引用文献NMR Studies of [U-13C]Cyclosporin a Bound to Cyclophilin: Bound Conformation and Portions of Cyclosporin Involved in Binding.
Biochemistry, 30, 1991