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1NST
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THE SULFOTRANSFERASE DOMAIN OF HUMAN HAPARIN SULFATE N-DEACETYLASE/N-SULFOTRANSFERASE
Descriptor:HEPARAN SULFATE N-DEACETYLASE/N-SULFOTRANSFERASE, ADENOSINE-3'-5'-DIPHOSPHATE
Authors:Kakuta, Y., Pedersen, L.C., Negishi, M.
Deposit date:1998-09-07
Release date:1999-09-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the sulfotransferase domain of human heparan sulfate N-deacetylase/ N-sulfotransferase 1.
J.Biol.Chem., 274, 1999
1QXM
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CRYSTAL STRUCTURE OF A HEMAGGLUTININ COMPONENT (HA1) FROM TYPE C CLOSTRIDIUM BOTULINUM
Descriptor:HA1, 1,2-ETHANEDIOL
Authors:Inoue, K., Sobhany, M., Transue, T.R., Oguma, K., Pedersen, L.C., Negishi, M.
Deposit date:2003-09-08
Release date:2004-01-20
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural analysis by X-ray crystallography and calorimetry of a haemagglutinin component (HA1) of the progenitor toxin from Clostridium botulinum.
Microbiology, 149, 2003
1AQU
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ESTROGEN SULFOTRANSFERASE WITH BOUND INACTIVE COFACTOR PAP AND 17-BETA ESTRADIOL
Descriptor:ESTROGEN SULFOTRANSFERASE, ADENOSINE-3'-5'-DIPHOSPHATE, ESTRADIOL
Authors:Kakuta, Y., Negishi, M., Pedersen, L.C.
Deposit date:1997-08-01
Release date:1998-10-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of estrogen sulphotransferase.
Nat.Struct.Biol., 4, 1997
1AQY
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ESTROGEN SULFOTRANSFERASE WITH PAP
Descriptor:ESTROGEN SULFOTRANSFERASE, ADENOSINE-3'-5'-DIPHOSPHATE
Authors:Kakuta, Y., Pedersen, L.G., Carter, C.W., Negishi, M., Pedersen, L.C.
Deposit date:1997-08-04
Release date:1998-10-28
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of estrogen sulphotransferase.
Nat.Struct.Biol., 4, 1997
1BO6
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ESTROGEN SULFOTRANSFERASE WITH INACTIVE COFACTOR PAP AND VANADATE
Descriptor:ESTROGEN SULFOTRANSFERASE, VANADATE ION, ADENOSINE-3'-5'-DIPHOSPHATE
Authors:Kakuta, Y., Negishi, M., Pedersen, L.C.
Deposit date:1998-08-10
Release date:1999-08-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The sulfuryl transfer mechanism. Crystal structure of a vanadate complex of estrogen sulfotransferase and mutational analysis.
J.Biol.Chem., 273, 1998
1CJM
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HUMAN SULT1A3 WITH SULFATE BOUND
Descriptor:PROTEIN (ARYL SULFOTRANSFERASE), SULFATE ION
Authors:Bidwell, L.M., Mcmanus, M.E., Gaedigk, A., Kakuta, Y., Negishi, M., Pedersen, L., Martin, J.L.
Deposit date:1999-04-18
Release date:1999-11-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of human catecholamine sulfotransferase.
J.Mol.Biol., 293, 1999
1EFH
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CRYSTAL STRUCTURE OF THE HUMAN HYDROXYSTEROID SULFOTRANSFERASE IN THE PRESENCE OF PAP
Descriptor:HYDROXYSTEROID SULFOTRANSFERASE, ADENOSINE-3'-5'-DIPHOSPHATE
Authors:Pedersen, L.C., Petrotchenko, E.V., Negishi, M.
Deposit date:2000-02-08
Release date:2000-09-06
Last modified:2018-06-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of SULT2A3, human hydroxysteroid sulfotransferase.
FEBS Lett., 475, 2000
1G3M
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CRYSTAL STRUCTURE OF HUMAN ESTROGEN SULFOTRANSFERASE IN COMPLEX WITH IN-ACTIVE COFACTOR PAP AND 3,5,3',5'-TETRACHLORO-BIPHENYL-4,4'-DIOL
Descriptor:ESTROGEN SULFOTRANSFERASE, ADENOSINE-3'-5'-DIPHOSPHATE, 3,5,3',5'-TETRACHLORO-BIPHENYL-4,4'-DIOL, ...
Authors:Shevtsov, S., Petrochenko, E.V., Negishi, M., Pedersen, L.C.
Deposit date:2000-10-24
Release date:2003-07-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystallographic analysis of a hydroxylated polychlorinated biphenyl (OH-PCB) bound to the catalytic estrogen binding site of human estrogen sulfotransferase.
Environ.Health Perspect., 111, 2003
1HY3
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CRYSTAL STRUCTURE OF HUMAN ESTROGEN SULFOTRANSFERASE V269E MUTANT IN THE PRESENCE OF PAPS
Descriptor:ESTROGEN SULFOTRANSFERASE, 3'-PHOSPHATE-ADENOSINE-5'-PHOSPHATE SULFATE
Authors:Pedersen, L.C., Petrochenko, E.V., Shevtsov, S., Negishi, M.
Deposit date:2001-01-17
Release date:2002-06-19
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the human estrogen sulfotransferase-PAPS complex: evidence for catalytic role of Ser137 in the sulfuryl transfer reaction.
J.Biol.Chem., 277, 2002
1KWS
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CRYSTAL STRUCTURE OF BETA1,3-GLUCURONYLTRANSFERASE I IN COMPLEX WITH THE ACTIVE UDP-GLCUA DONOR
Descriptor:BETA-1,3-GLUCURONYLTRANSFERASE 3, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE-GLUCURONIC ACID
Authors:Pedersen, L.C., Darden, T.A., Negishi, M.
Deposit date:2002-01-30
Release date:2002-06-19
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of beta 1,3-glucuronyltransferase I in complex with active donor substrate UDP-GlcUA.
J.Biol.Chem., 277, 2002
1OMX
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CRYSTAL STRUCTURE OF MOUSE ALPHA-1,4-N-ACETYLHEXOSAMINYLTRANSFERASE (EXTL2)
Descriptor:Alpha-1,4-N-acetylhexosaminyltransferase EXTL2, 1,2-ETHANEDIOL
Authors:Pedersen, L.C., Dong, J., Taniguchi, F., Kitagawa, H., Krahn, J.M., Pedersen, L.G., Sugahara, K., Negishi, M.
Deposit date:2003-02-26
Release date:2003-04-22
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of an alpha-1,4-N-acetylhexosaminyltransferase (EXTL2), a member of the exostosin gene family involved in heparan sulfate biosynthesis
J.Biol.Chem., 278, 2003
1OMZ
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CRYSTAL STRUCTURE OF MOUSE ALPHA-1,4-N-ACETYLHEXOSAMINYLTRANSFERASE (EXTL2) IN COMPLEX WITH UDPGALNAC
Descriptor:Alpha-1,4-N-acetylhexosaminyltransferase EXTL2, MANGANESE (II) ION, URIDINE-DIPHOSPHATE-N-ACETYLGALACTOSAMINE, ...
Authors:Pedersen, L.C., Dong, J., Taniguchi, F., Kitagawa, H., Krahn, J.M., Pedersen, L.G., Sugahara, K., Negishi, M.
Deposit date:2003-02-26
Release date:2003-04-22
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of an alpha-1,4-N-acetylhexosaminyltransferase (EXTL2), a member of the exostosin gene family involved in heparan sulfate biosynthesis
J.Biol.Chem., 278, 2003
1ON6
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CRYSTAL STRUCTURE OF MOUSE ALPHA-1,4-N-ACETYLHEXOSAMINOTRANSFERASE (EXTL2) IN COMPLEX WITH UDPGLCNAC
Descriptor:Alpha-1,4-N-acetylhexosaminyltransferase EXTL2, MANGANESE (II) ION, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE, ...
Authors:Pedersen, L.C., Dong, J., Taniguchi, F., Kitagawa, H., Krahn, J.M., Pedersen, L.G., Sugahara, K., Negishi, M.
Deposit date:2003-02-27
Release date:2003-04-22
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of an alpha-1,4-N-acetylhexosaminyltransferase (EXTL2), a member of the exostosin gene family involved in heparan sulfate biosynthesis
J.Biol.Chem., 278, 2003
1ON8
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CRYSTAL STRUCTURE OF MOUSE ALPHA-1,4-N-ACETYLHEXOSAMINYLTRANSFERASE (EXTL2) WITH UDP AND GLCUAB(1-3)GALB(1-O)-NAPHTHALENELMETHANOL AN ACCEPTOR SUBSTRATE ANALOG
Descriptor:Alpha-1,4-N-acetylhexosaminyltransferase EXTL2, BETA-D-GLUCOPYRANURONIC ACID, BETA-D-GALACTOSE, ...
Authors:Pedersen, L.C., Dong, J., Taniguchi, F., Kitagawa, H., Krahn, J.M., Pedersen, L.G., Sugahara, K., Negishi, M.
Deposit date:2003-02-27
Release date:2003-04-22
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of an alpha-1,4-N-acetylhexosaminyltransferase (EXTL2), a member of the exostosin gene family involved in heparan sulfate biosynthesis
J.Biol.Chem., 278, 2003
1Q1Q
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CRYSTAL STRUCTURE OF HUMAN PREGNENOLONE SULFOTRANSFERASE (SULT2B1A) IN THE PRESENCE OF PAP
Descriptor:sulfotransferase family, cytosolic, 2B, ...
Authors:Lee, K.A., Fuda, H., Lee, Y.C., Negishi, M., Strott, C.A., Pedersen, L.C.
Deposit date:2003-07-22
Release date:2003-11-11
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Crystal structure of human cholesterol sulfotransferase (SULT2B1b) in the presence of pregnenolone and 3'-phosphoadenosine 5'-phosphate. Rationale for specificity differences between prototypical SULT2A1 and the SULT2BG1 isoforms.
J.Biol.Chem., 278, 2003
1Q1Z
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CRYSTAL STRUCTURE OF HUMAN CHOLESTEROL SULFOTRANSFERASE (SULT2B1B) IN THE PRESENCE OF PAP
Descriptor:sulfotransferase family, cytosolic, 2B, ...
Authors:Lee, K.A., Fuda, H., Lee, Y.C., Negishi, M., Strott, C.A., Pedersen, L.C.
Deposit date:2003-07-23
Release date:2003-11-11
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of human cholesterol sulfotransferase (SULT2B1b) in the presence of pregnenolone and 3'-phosphoadenosine 5'-phosphate. Rationale for specificity differences between prototypical SULT2A1 and the SULT2BG1 isoforms.
J.Biol.Chem., 278, 2003
1Q20
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CRYSTAL STRUCTURE OF HUMAN CHOLESTEROL SULFOTRANSFERASE (SULT2B1B) IN THE PRESENCE OF PAP AND PREGNENOLONE
Descriptor:sulfotransferase family, cytosolic, 2B, ...
Authors:Lee, K.A., Fuda, H., Lee, Y.C., Negishi, M., Strott, C.A., Pedersen, L.C.
Deposit date:2003-07-23
Release date:2003-11-11
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of human cholesterol sulfotransferase (SULT2B1b) in the presence of pregnenolone and 3'-phosphoadenosine 5'-phosphate. Rationale for specificity differences between prototypical SULT2A1 and the SULT2BG1 isoforms.
J.Biol.Chem., 278, 2003
1Q22
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CRYSTAL STRUCTURE OF HUMAN CHOLESTEROL SULFOTRANSFERASE (SULT2B1B) IN THE PRESENCE OF DHEA AND PAP
Descriptor:sulfotransferase family, cytosolic, 2B, ...
Authors:Lee, K.A., Fuda, H., Lee, Y.C., Negishi, M., Strott, C.A., Pedersen, L.C.
Deposit date:2003-07-23
Release date:2003-11-11
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of human cholesterol sulfotransferase (SULT2B1b) in the presence of pregnenolone and 3'-phosphoadenosine 5'-phosphate. Rationale for specificity differences between prototypical SULT2A1 and the SULT2BG1 isoforms.
J.Biol.Chem., 278, 2003
1T8T
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CRYSTAL STRUCTURE OF HUMAN 3-O-SULFOTRANSFERASE-3 WITH BOUND PAP
Descriptor:heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1, ADENOSINE-3'-5'-DIPHOSPHATE, CITRIC ACID
Authors:Moon, A.F., Edavettal, S.C., Krahn, J.M., Munoz, E.M., Negishi, M., Linhardt, R.J., Liu, J., Pedersen, L.C.
Deposit date:2004-05-13
Release date:2004-08-31
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural analysis of the sulfotransferase (3-o-sulfotransferase isoform 3) involved in the biosynthesis of an entry receptor for herpes simplex virus 1
J.Biol.Chem., 279, 2004
1T8U
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CRYSTAL STRUCTURE OF HUMAN 3-O-SULFOTRANSFERASE-3 WITH BOUND PAP AND TETRASACCHARIDE SUBSTRATE
Descriptor:heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1, SULFATE ION, SODIUM ION, ...
Authors:Moon, A.F., Edavettal, S.C., Krahn, J.M., Munoz, E.M., Negishi, M., Linhardt, R.J., Liu, J., Pedersen, L.C.
Deposit date:2004-05-13
Release date:2004-08-31
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural analysis of the sulfotransferase (3-o-sulfotransferase isoform 3) involved in the biosynthesis of an entry receptor for herpes simplex virus 1
J.Biol.Chem., 279, 2004
1VKJ
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CRYSTAL STRUCTURE OF HEPARAN SULFATE 3-O-SULFOTRANSFERASE ISOFORM 1 IN THE PRESENCE OF PAP
Descriptor:heparan sulfate (glucosamine) 3-O-sulfotransferase 1, SULFATE ION, ADENOSINE-3'-5'-DIPHOSPHATE
Authors:Thorp, S., Lee, K.A., Negishi, M., Linhardt, R.J., Liu, J., Pedersen, L.C.
Deposit date:2004-05-25
Release date:2004-06-01
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure and mutational analysis of heparan sulfate 3-O-sulfotransferase isoform 1
J.Biol.Chem., 279, 2004
3CU0
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HUMAN BETA 1,3-GLUCURONYLTRANSFERASE I (GLCAT-I) IN COMPLEX WITH UDP AND GAL-GAL(6-SO4)-XYL(2-PO4)-O-SER
Descriptor:Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3, BETA-D-GALACTOSE, MANGANESE (II) ION, ...
Authors:Tone, Y., Pedersen, L.C., Yamamoto, T., Kitagawa, H., Nishihara-Shimizu, J., Tamura, J., Negishi, M., Sugahara, K.
Deposit date:2008-04-15
Release date:2008-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:2-o-phosphorylation of xylose and 6-o-sulfation of galactose in the protein linkage region of glycosaminoglycans influence the glucuronyltransferase-I activity involved in the linkage region synthesis.
J.Biol.Chem., 283, 2008
1FGG
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CRYSTAL STRUCTURE OF 1,3-GLUCURONYLTRANSFERASE I (GLCAT-I) COMPLEXED WITH GAL-GAL-XYL, UDP, AND MN2+
Descriptor:GLUCURONYLTRANSFERASE I, BETA-D-GALACTOSE, MANGANESE (II) ION, ...
Authors:Pedersen, L.C., Tsuchida, K., Kitagawa, H., Sugahara, K., Darden, T.A.
Deposit date:2000-07-28
Release date:2001-01-31
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Heparan/chondroitin sulfate biosynthesis. Structure and mechanism of human glucuronyltransferase I.
J.Biol.Chem., 275, 2000
2JPH
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NMR SOLUTION STRUCTURE OF THE RHO GTPASE BINDING DOMAIN OF HUMAN PLEXIN-B1
Descriptor:Plexin-B1
Authors:Tong, Y., Buck, M.
Deposit date:2007-05-11
Release date:2008-03-18
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Insights into Oncogenic Mutations of Plexin-B1 Based on the Solution Structure of the Rho GTPase Binding Domain
Structure, 16, 2008
2H8K
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HUMAN SULFOTRANFERASE SULT1C3 IN COMPLEX WITH PAP
Descriptor:SULT1C3 splice variant d, ADENOSINE-3'-5'-DIPHOSPHATE
Authors:Tempel, W., Dombrovski, L., Loppnau, P., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Plotnikov, A.N., Structural Genomics Consortium (SGC)
Deposit date:2006-06-07
Release date:2006-06-20
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural and chemical profiling of the human cytosolic sulfotransferases.
Plos Biol., 5, 2007
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