Author results

1X6M
  • Download 1x6m
  • View 1x6m
Molmil generated image of 1x6m
CRYSTAL STRUCTURE OF THE GLUTATHIONE-DEPENDENT FORMALDEHYDE-ACTIVATING ENZYME (GFA)
分子名称:Glutathione-dependent formaldehyde-activating enzyme, ZINC ION, SULFATE ION, ...
著者Neculai, A.M., Neculai, D., Vorholt, J.A., Becker, S.
登録日2004-08-11
公開日2004-11-23
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献A dynamic zinc redox switch
J.Biol.Chem., 280, 2005
1XA8
  • Download 1xa8
  • View 1xa8
Molmil generated image of 1xa8
CRYSTAL STRUCTURE ANALYSIS OF GLUTATHIONE-DEPENDENT FORMALDEHYDE-ACTIVATING ENZYME (GFA)
分子名称:Glutathione-dependent formaldehyde-activating enzyme, ZINC ION, SULFATE ION, ...
著者Neculai, A.M., Neculai, D., Griesinger, C., Vorholt, J.A., Becker, S.
登録日2004-08-25
公開日2004-11-23
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A dynamic zinc redox switch
J.Biol.Chem., 280, 2005
3CQT
  • Download 3cqt
  • View 3cqt
Molmil generated image of 3cqt
N53I V55L MUTANT OF FYN SH3 DOMAIN
分子名称:Proto-oncogene tyrosine-protein kinase Fyn
著者Neculai, A.M., Zarrine-Afsar, A., Howell, P.L., Davidson, A., Chan, H.S.
登録日2008-04-03
公開日2008-07-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Theoretical and experimental demonstration of the importance of specific nonnative interactions in protein folding.
Proc.Natl.Acad.Sci.Usa, 105, 2008
1Y1U
  • Download 1y1u
  • View 1y1u
Molmil generated image of 1y1u
STRUCTURE OF UNPHOSPHORYLATED STAT5A
分子名称:Signal transducer and activator of transcription 5A
著者Neculai, D., Neculai, A.M., Verrier, S., Straub, K., Klumpp, K., Pfitzner, E., Becker, S.
登録日2004-11-19
公開日2005-10-04
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (3.21 Å)
主引用文献Structure of the unphosphorylated STAT5a dimer
J.Biol.Chem., 280, 2005
3MSE
  • Download 3mse
  • View 3mse
Molmil generated image of 3mse
CRYSTAL STRUCTURE OF C-TERMINAL DOMAIN OF PF110239.
分子名称:Calcium-dependent protein kinase, putative, CALCIUM ION, ...
著者Wernimont, A.K., Artz, J.D., Hutchinson, A., Sullivan, H., Weadge, J., Tempel, W., Bochkarev, A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Hui, R., Lin, Y.H., Neculai, A.M., Amani, M., Structural Genomics Consortium (SGC)
登録日2010-04-29
公開日2010-06-23
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of C-terminal domain of PF110239
To be Published
3OZ6
  • Download 3oz6
  • View 3oz6
Molmil generated image of 3oz6
CRYSTAL STRUCTURE OF MAPK FROM CRYPTOSPORIDIUM PARVUM, CGD2_1960
分子名称:Mitogen-activated protein kinase 1, serine/threonine protein kinase, GLYCEROL
著者Wernimont, A.K., Lew, J., Lin, Y.H., Sullivan, H., Hassanali, A., Kozieradzki, I., Cossar, D., Arrowsmith, C.H., Bochkarev, A., Bountra, C., Edwards, A.M., Weigelt, J., Hui, R., Neculai, A.M., Hutchinson, A., Structural Genomics Consortium (SGC)
登録日2010-09-24
公開日2010-12-08
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Crystal structure of MapK from Cryptosporidium Parvum, cgd2_1960
To be Published
3P1W
  • Download 3p1w
  • View 3p1w
Molmil generated image of 3p1w
CRYSTAL STRUCTURE OF RAB GDI FROM PLASMODIUM FALCIPARUM, PFL2060C
分子名称:RabGDI protein
著者Wernimont, A.K., Neculai, A.M., Weadge, J., MacKenzie, F., Cossar, D., Tempel, W., Bochkarev, A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Langsley, G., Bosch, J., Hui, R., Pizzaro, J.C., Hutchinson, A., Structural Genomics Consortium (SGC)
登録日2010-09-30
公開日2010-12-15
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal Structure of RAB GDI from Plasmodium Falciparum, PFL2060c
To be published
3Q5I
  • Download 3q5i
  • View 3q5i
Molmil generated image of 3q5i
CRYSTAL STRUCTURE OF PBANKA_031420
分子名称:Protein kinase, CALCIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Wernimont, A.K., Hutchinson, A., Sullivan, H., Panico, E., Crombet, L., Cossar, D., Hassani, A., Vedadi, M., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Hui, R., Neculai, A.M., Amani, M., Structural Genomics Consortium (SGC)
登録日2010-12-28
公開日2011-06-01
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of CDPK1 from Plasmodium Bergheii, PBANKA_031420
To be Published
5FET
  • Download 5fet
  • View 5fet
Molmil generated image of 5fet
CRYSTAL STRUCTURE OF PVX_084705 IN PRESENCE OF COMPOUND 2
分子名称:cGMP-dependent protein kinase, putative, 4-[7-[(dimethylamino)methyl]-2-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-amine
著者Wernimont, A.K., Tempel, W., Walker, J.R., He, H., Seitova, A., Hills, T., Neculai, A.M., Baker, D.A., Flueck, C., Kettleborough, C.A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Hui, R., Hutchinson, A., El Bakkouri, M., Structural Genomics Consortium (SGC)
登録日2015-12-17
公開日2016-01-13
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (3.07 Å)
主引用文献Crystal Structure of PVX_084705 in presence of Compound 2
To be published
3E4B
  • Download 3e4b
  • View 3e4b
Molmil generated image of 3e4b
CRYSTAL STRUCTURE OF ALGK FROM PSEUDOMONAS FLUORESCENS WCS374R
分子名称:AlgK, CHLORIDE ION, GLYCEROL
著者Keiski, C.-L., Harwich, M., Jain, S., Neculai, A.M., Yip, P., Robinson, H., Whitney, J.C., Burrows, L.L., Ohman, D.E., Howell, P.L.
登録日2008-08-11
公開日2009-08-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献AlgK is a TPR-containing protein and the periplasmic component of a novel exopolysaccharide secretin.
Structure, 18, 2010
3I3T
  • Download 3i3t
  • View 3i3t
Molmil generated image of 3i3t
CRYSTAL STRUCTURE OF COVALENT UBIQUITIN-USP21 COMPLEX
分子名称:Ubiquitin carboxyl-terminal hydrolase 21, Ubiquitin, ZINC ION, ...
著者Neculai, D., Avvakumov, G.V., Walker, J.R., Xue, S., Butler-Cole, C., Weigelt, J., Bountra, C., Edwards, A.M., Arrowsmith, C.H., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
登録日2009-06-30
公開日2009-07-21
最終更新日2013-02-27
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献A strategy for modulation of enzymes in the ubiquitin system.
Science, 339, 2013
3V6E
  • Download 3v6e
  • View 3v6e
Molmil generated image of 3v6e
CRYSTAL STRUCTURE OF USP2 AND A MUTANT FORM OF UBIQUITIN
分子名称:Ubiquitin carboxyl-terminal hydrolase 2, Ubiquitin, ZINC ION, ...
著者Neculai, M., Ernst, A., Sidhu, S., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
登録日2011-12-19
公開日2012-12-19
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A strategy for modulation of enzymes in the ubiquitin system.
Science, 339, 2013
3MTN
  • Download 3mtn
  • View 3mtn
Molmil generated image of 3mtn
USP21 IN COMPLEX WITH A UBIQUITIN-BASED, USP21-SPECIFIC INHIBITOR
分子名称:Ubiquitin carboxyl-terminal hydrolase 21, UBIQUITIN VARIANT UBV.21.4, ZINC ION, ...
著者Walker, J.R., Avvakumov, G.V., Xue, S., Li, Y., Ernst, A., Sidhu, S., Weigelt, J., Bountra, C., Edwards, A.M., Arrowsmith, C.H., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
登録日2010-04-30
公開日2010-06-09
最終更新日2013-02-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A strategy for modulation of enzymes in the ubiquitin system.
Science, 339, 2013
3N3K
  • Download 3n3k
  • View 3n3k
Molmil generated image of 3n3k
THE CATALYTIC DOMAIN OF USP8 IN COMPLEX WITH A USP8 SPECIFIC INHIBITOR
分子名称:Ubiquitin carboxyl-terminal hydrolase 8, Ubiquitin, ZINC ION
著者Walker, J.R., Avvakumov, G.V., Xue, S., Li, Y., Allali-Hassani, A., Lam, R., Ernst, A., Sidhu, S., Weigelt, J., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium, Structural Genomics Consortium (SGC)
登録日2010-05-20
公開日2010-06-23
最終更新日2018-03-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A strategy for modulation of enzymes in the ubiquitin system.
Science, 339, 2013
4I6L
  • Download 4i6l
  • View 4i6l
Molmil generated image of 4i6l
CRYSTAL STRUCTURE OF OTUB1 IN COMPLEX WITH UBIQUITIN VARIANT
分子名称:Ubiquitin thioesterase OTUB1, Ubiquitin
著者Juang, Y.C., Sicheri, F.
登録日2012-11-29
公開日2013-01-16
最終更新日2013-02-20
実験手法X-RAY DIFFRACTION (2.488 Å)
主引用文献A strategy for modulation of enzymes in the ubiquitin system.
Science, 339, 2013
5DYK
  • Download 5dyk
  • View 5dyk
Molmil generated image of 5dyk
CRYSTAL STRUCTURE OF THE CGMP-DEPENDENT PROTEIN KINASE PKG FROM PLASMODIUM FALCIPARUM - APO FORM
分子名称:CGMP-dependent protein kinase, 1,2-ETHANEDIOL, SULFATE ION, ...
著者Wernimont, A.K., Tempel, W., He, H., Seitova, A., Hills, T., Neculai, A.M., Baker, D.A., Flueck, C., Kettleborough, C.A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Hui, R., Hutchinson, A., El Bakkouri, M., Structural Genomics Consortium (SGC)
登録日2015-09-24
公開日2015-11-04
最終更新日2019-07-03
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structures of the cGMP-dependent protein kinase in malaria parasites reveal a unique structural relay mechanism for activation
Proc.Natl.Acad.Sci.USA, 2019
5DYL
  • Download 5dyl
  • View 5dyl
Molmil generated image of 5dyl
CRYSTAL STRUCTURE OF THE CGMP-DEPENDENT PROTEIN KINASE PKG FROM PLASMODIUM VIVAX - APO FORM
分子名称:cGMP-dependent protein kinase, putative
著者Wernimont, A.K., Tempel, W., He, H., Seitova, A., Hills, T., Neculai, A.M., Baker, D.A., Flueck, C., Kettleborough, C.A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Hui, R., Hutchinson, A., El Bakkouri, M., Structural Genomics Consortium (SGC)
登録日2015-09-24
公開日2015-11-04
最終更新日2019-07-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structures of the cGMP-dependent protein kinase in malaria parasites reveal a unique structural relay mechanism for activation
Proc.Natl.Acad.Sci.USA, 2019
4RT0
  • Download 4rt0
  • View 4rt0
Molmil generated image of 4rt0
STRUCTURE OF THE ALG44 PILZ DOMAIN FROM PSEUDOMONAS AERUGINOSA PAO1 IN COMPLEX WITH C-DI-GMP
分子名称:Alginate biosynthesis protein Alg44, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), 1,2-ETHANEDIOL
著者Whitfield, G.B., Whitney, J.C.
登録日2014-11-12
公開日2015-04-08
最終更新日2015-06-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Dimeric c-di-GMP Is Required for Post-translational Regulation of Alginate Production in Pseudomonas aeruginosa.
J.Biol.Chem., 290, 2015
4RT1
  • Download 4rt1
  • View 4rt1
Molmil generated image of 4rt1
STRUCTURE OF THE ALG44 PILZ DOMAIN (R95A MUTANT) FROM PSEUDOMONAS AERUGINOSA PAO1 IN COMPLEX WITH C-DI-GMP
分子名称:Alginate biosynthesis protein Alg44, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CHLORIDE ION, ...
著者Whitfield, G.B., Whitney, J.C.
登録日2014-11-12
公開日2015-04-08
最終更新日2015-06-03
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Dimeric c-di-GMP Is Required for Post-translational Regulation of Alginate Production in Pseudomonas aeruginosa.
J.Biol.Chem., 290, 2015