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3S2R
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BU of 3s2r by Molmil
ATChloroNEET (H87C mutant)
Descriptor: AT5g51720/MIO24_14, FE2/S2 (INORGANIC) CLUSTER
Authors:livnah, O, Eisenberg-Domovich, Y, nechushtai, R.
Deposit date:2011-05-17
Release date:2012-05-23
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.14 Å)
Cite:Arabidopsis thaliana ChloroNEET, a Member of the New NEET Family of Human Proteins, is Involved in Development, Senescence and Iron Metabolism.
To be Published
3S2Q
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BU of 3s2q by Molmil
The crystal structure of AT5g51720 (AT-NEET)
Descriptor: AT5g51720/MIO24_14, FE2/S2 (INORGANIC) CLUSTER, ZINC ION
Authors:Livnah, O, Eisenberg-Domovich, Y, Nechushtai, R.
Deposit date:2011-05-17
Release date:2012-05-23
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Arabidopsis thaliana ChloroNEET, a Member of the New NEET Family of Human Proteins, is Involved in Development, Senescence and Iron Metabolism.
To be Published
3P63
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BU of 3p63 by Molmil
Structure of M. laminosus Ferredoxin with a shorter L1,2 loop
Descriptor: FE2/S2 (INORGANIC) CLUSTER, Ferredoxin
Authors:Livnah, O, Nechushtai, R, Eisenberg-Domovich, Y, Michaeli, D.
Deposit date:2010-10-11
Release date:2011-02-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Allostery in the ferredoxin protein motif does not involve a conformational switch.
Proc.Natl.Acad.Sci.USA, 108, 2011
6AVJ
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BU of 6avj by Molmil
Crystal structure of human Mitochondrial inner NEET protein (MiNT)/CISD3
Descriptor: CDGSH iron-sulfur domain-containing protein 3, mitochondrial, FE2/S2 (INORGANIC) CLUSTER
Authors:Lipper, C.H, Karmi, O, Sohn, Y.S, Darash-Yahana, M, Lammert, H, Song, L, Liu, A, Mittler, R, Nechushtai, R, Onuchic, J.N, Jennings, P.A.
Deposit date:2017-09-02
Release date:2017-12-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the human monomeric NEET protein MiNT and its role in regulating iron and reactive oxygen species in cancer cells.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
1RFK
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BU of 1rfk by Molmil
Crystal Structure of 2Fe2S Ferredoxin from Thermophilic Cyanobacterium Mastigocladus Laminosus
Descriptor: FE2/S2 (INORGANIC) CLUSTER, Ferredoxin
Authors:Fish, A, Nechushtai, R, Livnah, O.
Deposit date:2003-11-10
Release date:2005-04-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Structural basis for the thermostability of ferredoxin from the cyanobacterium Mastigocladus laminosus.
J.Mol.Biol., 350, 2005
7P0P
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BU of 7p0p by Molmil
NAF-1 bound to M1 molecule
Descriptor: 2-benzamido-4-[(2~{R})-1,2,3,4-tetrahydronaphthalen-2-yl]thiophene-3-carboxylic acid, CDGSH iron-sulfur domain-containing protein 2, FE2/S2 (INORGANIC) CLUSTER
Authors:Livnah, O, Eisenberg-Domovich, Y, Marjault, H.B, Nechushtai, R.
Deposit date:2021-06-30
Release date:2022-05-25
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:An anti-diabetic drug targets NEET (CISD) proteins through destabilization of their [2Fe-2S] clusters.
Commun Biol, 5, 2022
7P0O
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BU of 7p0o by Molmil
mitoNEET bound to M1 molecule
Descriptor: 2-benzamido-4-[(2~{R})-1,2,3,4-tetrahydronaphthalen-2-yl]thiophene-3-carboxylic acid, 2-benzamido-4-[(2~{S})-1,2,3,4-tetrahydronaphthalen-2-yl]thiophene-3-carboxylic acid, CDGSH iron-sulfur domain-containing protein 1, ...
Authors:Livnah, O, Eisenberg-Domovich, Y, Marjault, H.B, Nechushtai, R.
Deposit date:2021-06-30
Release date:2022-05-25
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:An anti-diabetic drug targets NEET (CISD) proteins through destabilization of their [2Fe-2S] clusters.
Commun Biol, 5, 2022
4OOA
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BU of 4ooa by Molmil
CRYSTAL STRUCTURE of NAF1 (MINER1): H114C THE REDOX-ACTIVE 2FE-2S PROTEIN
Descriptor: CDGSH iron-sulfur domain-containing protein 2, FE2/S2 (INORGANIC) CLUSTER
Authors:Tamir, S, Eisenberg-Domovich, Y, Conlan, A.R, Stofleth, J.T, Lipper, C.H, Paddock, M.L, Mittler, R, Jennings, P.A, Livnah, O, Nechushtai, R.
Deposit date:2014-01-31
Release date:2014-07-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:A point mutation in the [2Fe-2S] cluster binding region of the NAF-1 protein (H114C) dramatically hinders the cluster donor properties.
Acta Crystallogr.,Sect.D, 70, 2014
2QH7
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BU of 2qh7 by Molmil
MitoNEET is a uniquely folded 2Fe-2S outer mitochondrial membrane protein stabilized by pioglitazone
Descriptor: FE2/S2 (INORGANIC) CLUSTER, Zinc finger CDGSH-type domain 1
Authors:Paddock, M.L, Wiley, S.E, Axelrod, H.L, Cohen, A.E, Roy, M, Abresch, E.C, Capraro, D, Murphy, A.N, Nechushtai, R, Dixon, J.E, Jennings, P.A.
Deposit date:2007-06-30
Release date:2007-08-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:MitoNEET is a uniquely folded 2Fe 2S outer mitochondrial membrane protein stabilized by pioglitazone.
Proc.Natl.Acad.Sci.Usa, 104, 2007
4OO7
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BU of 4oo7 by Molmil
THE 1.55A CRYSTAL STRUCTURE of NAF1 (MINER1): THE REDOX-ACTIVE 2FE-2S PROTEIN
Descriptor: CDGSH iron-sulfur domain-containing protein 2, FE2/S2 (INORGANIC) CLUSTER
Authors:Tamir, S, Eisenberg-Domovich, Y, Colman, A.R, Stofleth, J.T, Lipper, C.H, Paddock, M.L, Jenning, P.A, Livnah, O, Nechushtai, R.
Deposit date:2014-01-31
Release date:2014-07-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:A point mutation in the [2Fe-2S] cluster binding region of the NAF-1 protein (H114C) dramatically hinders the cluster donor properties.
Acta Crystallogr.,Sect.D, 70, 2014
3LPQ
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BU of 3lpq by Molmil
Human MitoNEET with 2Fe-2S Coordinating Ligand His 87 Replaced With Cys
Descriptor: CDGSH iron sulfur domain-containing protein 1, FE2/S2 (INORGANIC) CLUSTER
Authors:Conlan, A.R, Homer, C, Axelrod, H.L, Cohen, A.E, Abresch, E.C, Zuris, J, Nechushtai, R, Paddock, M.L, Jennings, P.A.
Deposit date:2010-02-05
Release date:2011-06-01
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Mutation of the His ligand in mitoNEET stabilizes the 2Fe-2S cluster despite conformational heterogeneity in the ligand environment.
Acta Crystallogr.,Sect.D, 67, 2011
7A4P
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BU of 7a4p by Molmil
Structure of small high-light grown Chlorella ohadii photosystem I
Descriptor: (1~{S})-3,5,5-trimethyl-4-[(1~{E},3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-[(4~{S})-2,6,6-trimethyl-4-oxidanyl-cyclohexen-1-yl]octadeca-1,3,5,7,9,11,13,15,17-nonaenyl]cyclohex-3-en-1-ol, (2S)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-hydroxypropyl hexadecanoate, (3R)-beta,beta-caroten-3-ol, ...
Authors:Caspy, I, Nelson, N, Nechushtai, R, Shkolnisky, Y, Neumann, E.
Deposit date:2020-08-20
Release date:2021-07-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Cryo-EM photosystem I structure reveals adaptation mechanisms to extreme high light in Chlorella ohadii.
Nat.Plants, 7, 2021
6ZZX
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BU of 6zzx by Molmil
Structure of low-light grown Chlorella ohadii Photosystem I
Descriptor: (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (2S)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-hydroxypropyl hexadecanoate, (3R)-beta,beta-caroten-3-ol, ...
Authors:Caspy, I, Nelson, N, Nechushtai, R, Neumann, E, Shkolnisky, Y.
Deposit date:2020-08-05
Release date:2021-07-28
Last modified:2021-09-29
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Cryo-EM photosystem I structure reveals adaptation mechanisms to extreme high light in Chlorella ohadii.
Nat.Plants, 7, 2021
6ZZY
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BU of 6zzy by Molmil
Structure of high-light grown Chlorella ohadii photosystem I
Descriptor: (1~{S})-3,5,5-trimethyl-4-[(1~{E},3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-[(4~{S})-2,6,6-trimethyl-4-oxidanyl-cyclohexen-1-yl]octadeca-1,3,5,7,9,11,13,15,17-nonaenyl]cyclohex-3-en-1-ol, (2S)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-hydroxypropyl hexadecanoate, (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, ...
Authors:Caspy, I, Nelson, N, Nechushtai, R, Shkolnisky, Y, Neumann, E.
Deposit date:2020-08-05
Release date:2021-07-28
Last modified:2021-09-29
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:Cryo-EM photosystem I structure reveals adaptation mechanisms to extreme high light in Chlorella ohadii.
Nat.Plants, 7, 2021
3EW0
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BU of 3ew0 by Molmil
The novel 2Fe-2S outer mitochondrial protein mitoNEET displays conformational flexibility in its N-terminal cytoplasmic tethering domain
Descriptor: CDGSH iron sulfur domain-containing protein 1, FE2/S2 (INORGANIC) CLUSTER
Authors:Conlan, A.R, Paddock, M.L, Wiley, S, Axelrod, H.L, Cohen, A.E, Abresch, E.C, Roy, M, Nechushtai, R, Jennings, P.A.
Deposit date:2008-10-13
Release date:2009-07-07
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The novel 2Fe-2S outer mitochondrial protein mitoNEET displays conformational flexibility in its N-terminal cytoplasmic tethering domain.
Acta Crystallogr.,Sect.F, 65, 2009
3FNV
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BU of 3fnv by Molmil
Crystal Structure of Miner1: The Redox-active 2Fe-2S Protein Causative in Wolfram Syndrome 2
Descriptor: CDGSH iron sulfur domain-containing protein 2, FE2/S2 (INORGANIC) CLUSTER
Authors:Conlan, A.R, Axelrod, H.L, Cohen, A.E, Abresch, E.C, Yee, D, Zuris, J, Nechushtai, R, Jennings, P.A, Paddock, M.L.
Deposit date:2008-12-26
Release date:2009-08-18
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of Miner1: The redox-active 2Fe-2S protein causative in Wolfram Syndrome 2.
J.Mol.Biol., 392, 2009
4F2C
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BU of 4f2c by Molmil
The Crystal Structure of a Human MitoNEET double mutant in which Gly 66 are Asp 67 are both Replaced with Ala Residues
Descriptor: CDGSH iron-sulfur domain-containing protein 1, FE2/S2 (INORGANIC) CLUSTER
Authors:Baxter, E.L, Zuris, J.A, Wang, C, Axelrod, H.L, Cohen, A.E, Paddock, M.L, Nechushtai, R, Onuchic, J.N, Jennings, P.A.
Deposit date:2012-05-07
Release date:2012-12-26
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Allosteric control in a metalloprotein dramatically alters function.
Proc.Natl.Acad.Sci.USA, 110, 2013
4EZF
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BU of 4ezf by Molmil
The Crystal Structure of a Human MitoNEET mutant with an Ala inserted between Asp 67 and Lys 68
Descriptor: CDGSH iron-sulfur domain-containing protein 1, FE2/S2 (INORGANIC) CLUSTER
Authors:Baxter, E.L, Zuris, J.A, Wang, C, Axelrod, H.L, Cohen, A.E, Paddock, M.L, Nechushtai, R, Onuchic, J.N, Jennings, P.A.
Deposit date:2012-05-02
Release date:2012-12-26
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.19 Å)
Cite:Allosteric control in a metalloprotein dramatically alters function.
Proc.Natl.Acad.Sci.USA, 110, 2013
4F1E
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BU of 4f1e by Molmil
The Crystal Structure of a Human MitoNEET mutant with Asp 67 replaced by a Gly
Descriptor: CDGSH iron-sulfur domain-containing protein 1, FE2/S2 (INORGANIC) CLUSTER
Authors:Baxter, E.I, Zuris, J.A, Wang, C, Axelrod, H.L, Cohen, A.E, Paddock, M.L, Nechushtai, R, Onuchic, J.N, Jennings, P.A.
Deposit date:2012-05-06
Release date:2012-12-26
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Allosteric control in a metalloprotein dramatically alters function.
Proc.Natl.Acad.Sci.USA, 110, 2013
4F28
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BU of 4f28 by Molmil
The Crystal Structure of a Human MitoNEET mutant with Met 62 Replaced by a Gly
Descriptor: CDGSH iron-sulfur domain-containing protein 1, FE2/S2 (INORGANIC) CLUSTER
Authors:Baxter, E.L, Zuris, J.A, Wang, C, Axelrod, H.L, Cohen, A.E, Paddock, M.L, Nechushtai, R, Onuchic, J.N, Jennings, P.A.
Deposit date:2012-05-07
Release date:2012-12-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Allosteric control in a metalloprotein dramatically alters function.
Proc.Natl.Acad.Sci.USA, 110, 2013

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