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1C1Y
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BU of 1c1y by Molmil
CRYSTAL STRUCTURE OF RAP.GMPPNP IN COMPLEX WITH THE RAS-BINDING-DOMAIN OF C-RAF1 KINASE (RAFRBD).
Descriptor: CALCIUM ION, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Nassar, N.
Deposit date:1999-07-22
Release date:1999-08-02
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue.
Nature, 375, 1995
1GUA
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BU of 1gua by Molmil
HUMAN RAP1A, RESIDUES 1-167, DOUBLE MUTANT (E30D,K31E) COMPLEXED WITH GPPNHP AND THE RAS-BINDING-DOMAIN OF HUMAN C-RAF1, RESIDUES 51-131
Descriptor: C-RAF1, CALCIUM ION, MAGNESIUM ION, ...
Authors:Nassar, N, Wittinghofer, A.
Deposit date:1996-06-18
Release date:1997-01-11
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Ras/Rap effector specificity determined by charge reversal.
Nat.Struct.Biol., 3, 1996
2NGR
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BU of 2ngr by Molmil
TRANSITION STATE COMPLEX FOR GTP HYDROLYSIS BY CDC42: COMPARISONS OF THE HIGH RESOLUTION STRUCTURES FOR CDC42 BOUND TO THE ACTIVE AND CATALYTICALLY COMPROMISED FORMS OF THE CDC42-GAP.
Descriptor: ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Nassar, N, Hoffman, G, Clardy, J, Cerione, R.
Deposit date:1998-07-31
Release date:1999-01-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of Cdc42 bound to the active and catalytically compromised forms of Cdc42GAP.
Nat.Struct.Biol., 5, 1998
1GRN
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BU of 1grn by Molmil
CRYSTAL STRUCTURE OF THE CDC42/CDC42GAP/ALF3 COMPLEX.
Descriptor: ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Nassar, N, Hoffman, G.R, Clardy, J.C, Cerione, R.A.
Deposit date:1998-07-30
Release date:1999-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of Cdc42 bound to the active and catalytically compromised forms of Cdc42GAP.
Nat.Struct.Biol., 5, 1998
1XJ0
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BU of 1xj0 by Molmil
Crystal Structure of the GDP-bound form of the RasG60A mutant
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Transforming protein p21/H-Ras-1
Authors:Nassar, N, Skowronek, K.
Deposit date:2004-09-22
Release date:2005-05-10
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of an intermediate for nucleotide exchange by Ras
To be Published
3LO5
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BU of 3lo5 by Molmil
Crystal Structure of the dominant negative S17N mutant of Ras
Descriptor: CALCIUM ION, GTPase HRas, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Nassar, N, Singh, K, Garcia-Diaz, M.
Deposit date:2010-02-03
Release date:2010-03-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.568 Å)
Cite:Structure of the Dominant Negative S17N Mutant of Ras
Biochemistry, 49, 2010
2H0Q
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BU of 2h0q by Molmil
Crystal Structure of the PGM domain of the Suppressor of T-Cell receptor (Sts-1)
Descriptor: Suppressor of T-cell receptor signaling 1
Authors:Nassar, N, Ford, B, Carpino, N.
Deposit date:2006-05-15
Release date:2007-11-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:A phosphatase activity of Sts-1 contributes to the suppression of TCR signaling.
Mol.Cell, 27, 2007
3MBK
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BU of 3mbk by Molmil
The 1.35 A Structure of the Phosphatase Domain of the Suppressor of T Cell Receptor Signalling Protein in Complex with Sulphate
Descriptor: SULFATE ION, Ubiquitin-associated and SH3 domain-containing protein B
Authors:Nassar, N, Jakoncic, J.
Deposit date:2010-03-25
Release date:2010-06-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:The 1.35 A resolution structure of the phosphatase domain of the suppressor of T-cell receptor signaling protein in complex with sulfate.
Acta Crystallogr.,Sect.F, 66, 2010
3DB1
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BU of 3db1 by Molmil
Crystal structure of the 2H-phosphatase domain of Sts-2 in complex with phosphate
Descriptor: PHOSPHATE ION, STS-2 protein
Authors:Nassar, N, Chen, Y, Carpino, N.
Deposit date:2008-05-30
Release date:2009-03-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Structural and functional characterization of the 2H-phosphatase domain of Sts-2 reveals an acid-dependent phosphatase activity.
Biochemistry, 48, 2009
1A12
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BU of 1a12 by Molmil
REGULATOR OF CHROMOSOME CONDENSATION (RCC1) OF HUMAN
Descriptor: REGULATOR OF CHROMOSOME CONDENSATION 1
Authors:Renault, L, Nassar, N, Vetter, I, Becker, J, Roth, M, Wittinghofer, A.
Deposit date:1997-12-19
Release date:1999-01-13
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The 1.7 A crystal structure of the regulator of chromosome condensation (RCC1) reveals a seven-bladed propeller.
Nature, 392, 1998
2IKQ
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BU of 2ikq by Molmil
Crystal structure of mouse Sts-1 PGM domain in complex with phosphate
Descriptor: PHOSPHATE ION, Suppressor of T-cell receptor signaling 1
Authors:Chen, Y, Nassar, N.
Deposit date:2006-10-02
Release date:2007-08-14
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.609 Å)
Cite:A Phosphatase Activity of Sts-1 Contributes to the Suppression of TCR Signaling
Mol.Cell, 27, 2007
1DOA
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BU of 1doa by Molmil
Structure of the rho family gtp-binding protein cdc42 in complex with the multifunctional regulator rhogdi
Descriptor: GERAN-8-YL GERAN, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Hoffman, G.R, Nassar, N, Cerione, R.C.
Deposit date:1999-12-20
Release date:2000-02-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the Rho family GTP-binding protein Cdc42 in complex with the multifunctional regulator RhoGDI.
Cell(Cambridge,Mass.), 100, 2000
1LF5
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BU of 1lf5 by Molmil
Crystal Structure of RasA59G in the GDP-bound Form
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Transforming protein P21/H-RAS-1
Authors:Hall, B.E, Bar-Sagi, D, Nassar, N.
Deposit date:2002-04-10
Release date:2002-11-06
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Structural Basis for the Transition from Ras-GTP to Ras-GDP
Proc.Natl.Acad.Sci.USA, 99, 2002
1LF0
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BU of 1lf0 by Molmil
Crystal Structure of RasA59G in the GTP-bound form
Descriptor: CALCIUM ION, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Hall, B.E, Bar-Sagi, D, Nassar, N.
Deposit date:2002-04-10
Release date:2002-11-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Structural Basis for the Transition from Ras-GTP to Ras-GDP
Proc.Natl.Acad.Sci.USA, 99, 2002
1ZW6
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BU of 1zw6 by Molmil
Crystal Structure of the GTP-bound form of RasQ61G
Descriptor: CALCIUM ION, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Ford, B, Hornak, V, Kleinman, H, Nassar, N.
Deposit date:2005-06-03
Release date:2006-03-14
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of a transient intermediate for GTP hydrolysis by ras.
Structure, 14, 2006
1ZVQ
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BU of 1zvq by Molmil
Structure of the Q61G mutant of Ras in the GDP-bound form
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Transforming protein p21/H-Ras-1
Authors:Ford, B, Nassar, N.
Deposit date:2005-06-02
Release date:2006-03-14
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of a transient intermediate for GTP hydrolysis by ras.
Structure, 14, 2006
1NI2
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BU of 1ni2 by Molmil
Structure of the active FERM domain of Ezrin
Descriptor: Ezrin
Authors:Smith, W.J, Nassar, N, Bretscher, A.P, Cerione, R.A, Karplus, P.A.
Deposit date:2002-12-20
Release date:2003-02-25
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the Active N-terminal Domain of Ezrin. CONFORMATIONAL AND MOBILITY CHANGES IDENTIFY KEYSTONE INTERACTIONS.
J.Biol.Chem., 278, 2003
1NTY
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BU of 1nty by Molmil
Crystal structure of the first DH/PH domain of Trio to 1.7 A
Descriptor: Triple functional domain protein
Authors:Skowronek, K.R, Zheng, Y, Nassar, N.
Deposit date:2003-01-30
Release date:2004-06-29
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The C-terminal basic tail of RhoG assists the guanine nucleotide exchange factor trio in binding to phospholipids.
J.Biol.Chem., 279, 2004
3C7T
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BU of 3c7t by Molmil
Crystal structure of the ecdysone phosphate phosphatase, EPPase, from Bombix mori in complex with tungstate
Descriptor: CHLORIDE ION, Ecdysteroid-phosphate phosphatase, IODIDE ION, ...
Authors:Chen, Y, Carpino, N, Nassar, N.
Deposit date:2008-02-08
Release date:2009-03-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structural and functional characterization of the c-terminal domain of the ecdysteroid phosphate phosphatase from Bombyx mori reveals a new enzymatic activity.
Biochemistry, 47, 2008
3D4I
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BU of 3d4i by Molmil
Crystal structure of the 2H-phosphatase domain of Sts-2
Descriptor: CHLORIDE ION, Sts-2 protein
Authors:Chen, Y, Carpino, N, Nassar, N.
Deposit date:2008-05-14
Release date:2009-03-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural and functional characterization of the 2H-phosphatase domain of Sts-2 reveals an acid-dependent phosphatase activity.
Biochemistry, 48, 2009
3D6A
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BU of 3d6a by Molmil
Crystal structure of the 2H-phosphatase domain of Sts-2 in complex with tungstate.
Descriptor: MAGNESIUM ION, SODIUM ION, Sts-2 protein, ...
Authors:Chen, Y, Carpino, N, Nassar, N.
Deposit date:2008-05-19
Release date:2009-03-03
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural and functional characterization of the 2H-phosphatase domain of Sts-2 reveals an acid-dependent phosphatase activity.
Biochemistry, 48, 2009
1XCM
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BU of 1xcm by Molmil
Crystal structure of the GppNHp-bound H-Ras G60A mutant
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Transforming protein p21/H-Ras-1
Authors:Ford, B, Nassar, N.
Deposit date:2004-09-02
Release date:2005-05-10
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Crystal structure of the GppNHp-bound form of the RasG60A mutant
To be Published
2DFK
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BU of 2dfk by Molmil
Crystal structure of the CDC42-Collybistin II complex
Descriptor: GLYCEROL, SULFATE ION, cell division cycle 42 isoform 1, ...
Authors:Xiang, S, Kim, E.Y, Connelly, J.J, Nassar, N, Kirsch, J, Winking, J, Schwarz, G, Schindelin, H.
Deposit date:2006-03-02
Release date:2006-05-02
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The Crystal Structure of Cdc42 in Complex with Collybistin II, a Gephyrin-interacting Guanine Nucleotide Exchange Factor.
J.Mol.Biol., 359, 2006
1SET
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BU of 1set by Molmil
CRYSTAL STRUCTURES AT 2.5 ANGSTROMS RESOLUTION OF SERYL-TRNA SYNTHETASE COMPLEXED WITH TWO DIFFERENT ANALOGUES OF SERYL-ADENYLATE
Descriptor: 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, SERYL-tRNA SYNTHETASE
Authors:Cusack, S, Belrhali, H.
Deposit date:1994-02-21
Release date:1994-07-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal structures at 2.5 angstrom resolution of seryl-tRNA synthetase complexed with two analogs of seryl adenylate.
Science, 263, 1994
1SER
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BU of 1ser by Molmil
THE 2.9 ANGSTROMS CRYSTAL STRUCTURE OF T. THERMOPHILUS SERYL-TRNA SYNTHETASE COMPLEXED WITH TRNA SER
Descriptor: PROTEIN (SERYL-TRNA SYNTHETASE (E.C.6.1.1.11)), TRNASER
Authors:Biou, S, Cusack, V, Yaremchuk, A, Tukalo, M.
Deposit date:1994-02-21
Release date:1994-04-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The 2.9 A crystal structure of T. thermophilus seryl-tRNA synthetase complexed with tRNA(Ser).
Science, 263, 1994

 

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