Author results

1E5Y
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AZURIN FROM PSEUDOMONAS AERUGINOSA, REDUCED FORM, PH 5.5
Descriptor:AZURIN, COPPER (II) ION, NITRATE ION
Authors:Nar, H., Messerschmidt, A.
Deposit date:2000-08-04
Release date:2000-08-19
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (2 Å)
Cite:Rontgenkristallographische Strukturaufklarung Von Azurin Aus Pseudomonas Aeruginosa
Ph.D. Thesis, 1992
1E5Z
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AZURIN FROM PSEUDOMONAS AERUGINOSA, REDUCED FORM, PH 9.0
Descriptor:AZURIN, COPPER (II) ION, NITRATE ION
Authors:Nar, H., Messerschmidt, A.
Deposit date:2000-08-04
Release date:2000-08-19
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:Rontgenkristallographische Strukturaufklarung Von Azurin Aus Pseudomonas Aeruginosa
Ph.D. Thesis, 1992
1E65
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AZURIN FROM PSEUDOMONAS AERUGINOSA, APO FORM
Descriptor:AZURIN
Authors:Nar, H., Messerschmidt, A.
Deposit date:2000-08-08
Release date:2000-08-16
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal Structure of Pseudomonas Aeruginosa Apo-Azurin at 1.85 A Resolution.
FEBS Lett., 306, 1992
1E67
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ZN-AZURIN FROM PSEUDOMONAS AERUGINOSA
Descriptor:AZURIN, ZINC ION, NITRATE ION
Authors:Nar, H., Messerschmidt, A.
Deposit date:2000-08-09
Release date:2000-08-16
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Characterization and Crystal Structure of Zinc Azurin, a by-Product of Heterologous Expression in Escherichia Coli of Pseudomonas Aeruginosa Copper Azurin
Eur.J.Biochem., 205, 1992
4AZU
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CRYSTAL STRUCTURE ANALYSIS OF OXIDIZED PSEUDOMONAS AERUGINOSA AZURIN AT PH 5.5 AND PH 9.0. A PH-INDUCED CONFORMATIONAL TRANSITION INVOLVES A PEPTIDE BOND FLIP
Descriptor:AZURIN, COPPER (II) ION, NITRATE ION
Authors:Nar, H., Messerschmidt, A., Huber, R.
Deposit date:1993-06-23
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure analysis of oxidized Pseudomonas aeruginosa azurin at pH 5.5 and pH 9.0. A pH-induced conformational transition involves a peptide bond flip.
J.Mol.Biol., 221, 1991
5AZU
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CRYSTAL STRUCTURE ANALYSIS OF OXIDIZED PSEUDOMONAS AERUGINOSA AZURIN AT PH 5.5 AND PH 9.0. A PH-INDUCED CONFORMATIONAL TRANSITION INVOLVES A PEPTIDE BOND FLIP
Descriptor:AZURIN, COPPER (II) ION, NITRATE ION
Authors:Nar, H., Messerschmidt, A., Huber, R.
Deposit date:1993-06-23
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure analysis of oxidized Pseudomonas aeruginosa azurin at pH 5.5 and pH 9.0. A pH-induced conformational transition involves a peptide bond flip.
J.Mol.Biol., 221, 1991
1JIZ
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CRYSTAL STRUCTURE ANALYSIS OF HUMAN MACROPHAGE ELASTASE MMP-12
Descriptor:macrophage elastase MMP-12, ZINC ION, CALCIUM ION, ...
Authors:Nar, H., Werle, K., Bauer, M.M.T., Dollinger, H., Jung, B.
Deposit date:2001-07-03
Release date:2002-07-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of human macrophage elastase (MMP-12) in complex with a hydroxamic acid inhibitor.
J.Mol.Biol., 312, 2001
1DB2
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CRYSTAL STRUCTURE OF NATIVE PLASMINOGEN ACTIVATOR INHIBITOR-1
Descriptor:PLASMINOGEN ACTIVATOR INHIBITOR-1
Authors:Nar, H., Bauer, M., Stassen, J.M., Lang, D., Gils, A., Declerck, P.
Deposit date:1999-11-02
Release date:1999-11-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Plasminogen activator inhibitor 1. Structure of the native serpin, comparison to its other conformers and implications for serpin inactivation.
J.Mol.Biol., 297, 2000
1G2L
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FACTOR XA INHIBITOR COMPLEX
Descriptor:COAGULATION FACTOR X, CALCIUM ION, [(1-{2[(4-CARBAMIMIDOYL-PHENYLAMINO)-METHYL]-1-METHYL-1H-BENZOIMIDAZOL-5-YL}-CYCLOPROPYL)-PYRIDIN-2-YL-METHYLENEAMINOOXY]-ACETIC ACID ETHYL ESTER
Authors:Nar, H.
Deposit date:2000-10-20
Release date:2001-10-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for inhibition promiscuity of dual specific thrombin and factor Xa blood coagulation inhibitors.
Structure, 9, 2001
1G2M
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FACTOR XA INHIBITOR COMPLEX
Descriptor:COAGULATION FACTOR X, CALCIUM ION, 4-{[1-METHYL-5-(2-METHYL-BENZOIMIDAZOL-1-YLMETHYL)-1H-BENZOIMIDAZOL-2-YLMETHYL]-AMINO}-BENZAMIDINE
Authors:Nar, H.
Deposit date:2000-10-20
Release date:2001-10-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.02 Å)
Cite:Structural basis for inhibition promiscuity of dual specific thrombin and factor Xa blood coagulation inhibitors.
Structure, 9, 2001
1G30
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THROMBIN INHIBITOR COMPLEX
Descriptor:PROTHROMBIN, HIRUDIN IIB, [(1-{2[(4-CARBAMIMIDOYL-PHENYLAMINO)-METHYL]-1-METHYL-1H-BENZOIMIDAZOL-5-YL}-CYCLOPROPYL)-PYRIDIN-2-YL-METHYLENEAMINOOXY]-ACETIC ACID ETHYL ESTER
Authors:Nar, H.
Deposit date:2000-10-23
Release date:2001-10-23
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for inhibition promiscuity of dual specific thrombin and factor Xa blood coagulation inhibitors.
Structure, 9, 2001
1G32
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THROMBIN INHIBITOR COMPLEX
Descriptor:PROTHROMBIN, HIRUDIN IIB, 4-{[1-METHYL-5-(2-METHYL-BENZOIMIDAZOL-1-YLMETHYL)-1H-BENZOIMIDAZOL-2-YLMETHYL]-AMINO}-BENZAMIDINE
Authors:Nar, H.
Deposit date:2000-10-23
Release date:2001-10-23
Last modified:2013-03-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for inhibition promiscuity of dual specific thrombin and factor Xa blood coagulation inhibitors.
Structure, 9, 2001
1G36
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TRYPSIN INHIBITOR COMPLEX
Descriptor:TRYPSINOGEN, CATIONIC, CALCIUM ION, ...
Authors:Nar, H.
Deposit date:2000-10-23
Release date:2001-10-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for inhibition promiscuity of dual specific thrombin and factor Xa blood coagulation inhibitors.
Structure, 9, 2001
1GTP
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GTP CYCLOHYDROLASE I
Descriptor:GTP CYCLOHYDROLASE I, SULFATE ION
Authors:Nar, H., Huber, R., Meining, W., Bacher, A.
Deposit date:1995-09-16
Release date:1996-11-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Atomic structure of GTP cyclohydrolase I.
Structure, 3, 1995
1GTQ
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6-PYRUVOYL TETRAHYDROPTERIN SYNTHASE
Descriptor:6-PYRUVOYL TETRAHYDROPTERIN SYNTHASE, ZINC ION
Authors:Nar, H., Huber, R., Heizmann, C.W., Thoeny, B., Buergisser, D.
Deposit date:1995-09-16
Release date:1996-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Three-dimensional structure of 6-pyruvoyl tetrahydropterin synthase, an enzyme involved in tetrahydrobiopterin biosynthesis.
EMBO J., 13, 1994
1OYQ
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TRYPSIN INHIBITOR COMPLEX
Descriptor:Trypsin, cationic, CALCIUM ION, ...
Authors:Nar, H.
Deposit date:2003-04-07
Release date:2003-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis for Inhibition Promiscuity of Dual Specific Thrombin and Factor Xa Blood Coagulation Inhibitors
Structure, 9, 2001
2AZU
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X-RAY CRYSTAL STRUCTURE OF THE TWO SITE-SPECIFIC MUTANTS HIS35*GLN AND HIS35*LEU OF AZURIN FROM PSEUDOMONAS AERUGINOSA
Descriptor:AZURIN, COPPER (II) ION, NITRATE ION
Authors:Nar, H., Messerschmidt, A., Huber, R.
Deposit date:1991-01-11
Release date:1993-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:X-ray crystal structure of the two site-specific mutants His35Gln and His35Leu of azurin from Pseudomonas aeruginosa.
J.Mol.Biol., 218, 1991
3NJW
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FIRST HIGH RESOLUTION CRYSTAL STRUCTURE OF A LASSO PEPTIDE
Descriptor:Bicyclic peptide BI-32169
Authors:Nar, H., Schmid, A., Puder, C., Potterat, O.
Deposit date:2010-06-18
Release date:2010-09-01
Last modified:2011-08-10
Method:X-RAY DIFFRACTION (0.86 Å)
Cite:High-resolution crystal structure of a lasso Peptide.
Chemmedchem, 5, 2010
1KTS
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THROMBIN INHIBITOR COMPLEX
Descriptor:thrombin, hirudin IIB, 3-({2-[(4-CARBAMIMIDOYL-PHENYLAMINO)-METHYL]-3-METHYL-3H-BENZOIMIDAZOLE-5-CARBONYL}-PYRIDIN-2-YL-AMINO)-PROPIONIC ACID ETHYL ESTER
Authors:Nar, H.
Deposit date:2002-01-17
Release date:2002-02-06
Last modified:2013-03-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure-based design of novel potent nonpeptide thrombin inhibitors.
J.Med.Chem., 45, 2002
1KTT
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THROMBIN INHIBITOR COMPLEX
Descriptor:thrombin, hirudin IIB, 4-(5-BENZENESULFONYLAMINO-1-METHYL-1H-BENZOIMIDAZOL-2-YLMETHYL)-BENZAMIDINE
Authors:Nar, H.
Deposit date:2002-01-17
Release date:2002-02-06
Last modified:2013-03-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure-based design of novel potent nonpeptide thrombin inhibitors.
J.Med.Chem., 45, 2002
2RGU
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CRYSTAL STRUCTURE OF COMPLEX OF HUMAN DPP4 AND INHIBITOR
Descriptor:Dipeptidyl peptidase 4, N-ACETYL-D-GLUCOSAMINE, 8-[(3R)-3-Aminopiperidin-1-yl]-7-but-2-yn-1-yl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-3,7-dihydro-1H-purine-2,6-dione
Authors:Nar, H., Himmelsbach, F., Eckhardt, M.
Deposit date:2007-10-05
Release date:2007-11-06
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:8-(3-(R)-Aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydropurine-2,6-dione (BI 1356), a Highly Potent, Selective, Long-Acting, and Orally Bioavailable DPP-4 Inhibitor for the Treatment of Type 2 Diabetes.
J.Med.Chem., 50, 2007
1ZUX
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EOSFP FLUORESCENT PROTEIN- GREEN FORM
Descriptor:green to red photoconvertible GPF-like protein EosFP
Authors:Nar, H., Nienhaus, K., Wiedenmann, J., Nienhaus, G.U.
Deposit date:2005-06-01
Release date:2005-06-28
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural basis for photo-induced protein cleavage and green-to-red conversion of fluorescent protein EosFP.
Proc.Natl.Acad.Sci.Usa, 102, 2005
2BTJ
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FLUORESCENT PROTEIN EOSFP - RED FORM
Descriptor:GREEN TO RED PHOTOCONVERTIBLE GPF-LIKE PROTEIN EOSFP
Authors:Nar, H., Nienhaus, K., Wiedenmann, J., Nienhaus, G.U.
Deposit date:2005-06-01
Release date:2005-06-23
Last modified:2013-07-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for Photo-Induced Protein Cleavage and Green-to-Red Conversion of Fluorescent Protein Eosfp.
Proc.Natl.Acad.Sci.USA, 102, 2005
3AZU
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X-RAY CRYSTAL STRUCTURE OF THE TWO SITE-SPECIFIC MUTANTS HIS35GLN AND HIS35LEU OF AZURIN FROM PSEUDOMONAS AERUGINOSA
Descriptor:AZURIN, COPPER (II) ION
Authors:Messerschmidt, A., Nar, H., Huber, R.
Deposit date:1991-01-11
Release date:1993-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:X-ray crystal structure of the two site-specific mutants His35Gln and His35Leu of azurin from Pseudomonas aeruginosa.
J.Mol.Biol., 218, 1991
3E5T
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CRYSTAL STRUCTURE ANALYSIS OF FP611
Descriptor:Red fluorescent protein eqFP611
Authors:Nar, H., Nienhaus, K., Nienhaus, U., Wiedenmann, J.
Deposit date:2008-08-14
Release date:2008-09-23
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Trans-cis isomerization is responsible for the red-shifted fluorescence in variants of the red fluorescent protein eqFP611.
J.Am.Chem.Soc., 130, 2008