Author results

1ZCA
  • Download 1zca
  • View 1zca
Molmil generated image of 1zca
CRYSTAL STRUCTURE OF G ALPHA 12 IN COMPLEX WITH GDP, MG2+ AND ALF4-
Descriptor:G alpha i/12, MAGNESIUM ION, TETRAFLUOROALUMINATE ION, ...
Authors:Nance, M.R., Tesmer, J.J.G.
Deposit date:2005-04-11
Release date:2005-11-15
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A new approach to producing functional G alpha subunits yields the activated and deactivated structures of G alpha(12/13) proteins.
Biochemistry, 45, 2006
1ZCB
  • Download 1zcb
  • View 1zcb
Molmil generated image of 1zcb
CRYSTAL STRUCTURE OF G ALPHA 13 IN COMPLEX WITH GDP
Descriptor:G alpha i/13, GUANOSINE-5'-DIPHOSPHATE
Authors:Nance, M.R., Tesmer, J.J.G.
Deposit date:2005-04-11
Release date:2005-11-15
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:A new approach to producing functional G alpha subunits yields the activated and deactivated structures of G alpha(12/13) proteins.
Biochemistry, 45, 2006
2I1K
  • Download 2i1k
  • View 2i1k
Molmil generated image of 2i1k
MOESIN FROM SPODOPTERA FRUGIPERDA REVEALS THE COILED-COIL DOMAIN AT 3.0 ANGSTROM RESOLUTION
Descriptor:Moesin, CHLORIDE ION, UREA, ...
Authors:Nance, M.R., Tesmer, J.J.G.
Deposit date:2006-08-14
Release date:2006-12-19
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:Self-masking in an Intact ERM-merlin Protein: An Active Role for the Central alpha-Helical Domain.
J.Mol.Biol., 365, 2007
3PUH
  • Download 3puh
  • View 3puh
Molmil generated image of 3puh
COCAINE ESTERASE, WILD-TYPE BIOLOGICALLY ACTIVE DIMER
Descriptor:Cocaine esterase, GLYCEROL, SULFATE ION
Authors:Nance, M.R., Tesmer, J.J.G.
Deposit date:2010-12-04
Release date:2011-09-21
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Subunit stabilization and polyethylene glycolation of cocaine esterase improves in vivo residence time.
Mol.Pharmacol., 80, 2011
3PUI
  • Download 3pui
  • View 3pui
Molmil generated image of 3pui
COCAINE ESTERASE WITH MUTATIONS G4C, S10C
Descriptor:Cocaine esterase, CHLORIDE ION, SODIUM ION
Authors:Nance, M.R., Tesmer, J.J.G.
Deposit date:2010-12-04
Release date:2011-09-21
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Subunit stabilization and polyethylene glycolation of cocaine esterase improves in vivo residence time.
Mol.Pharmacol., 80, 2011
4EKC
  • Download 4ekc
  • View 4ekc
Molmil generated image of 4ekc
STRUCTURE OF HUMAN REGULATOR OF G PROTEIN SIGNALING 2 (RGS2) IN COMPLEX WITH MURINE GALPHA-Q(R183C)
Descriptor:Guanine nucleotide-binding protein G(q) subunit alpha, Regulator of G-protein signaling 2, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Tesmer, J.J.G., Nance, M.R.
Deposit date:2012-04-09
Release date:2013-01-30
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (7.4 Å)
Cite:Structural and functional analysis of the regulator of G protein signaling 2-g alpha q complex.
Structure, 21, 2013
4EKD
  • Download 4ekd
  • View 4ekd
Molmil generated image of 4ekd
STRUCTURE OF HUMAN REGULATOR OF G PROTEIN SIGNALING 2 (RGS2) IN COMPLEX WITH MURINE GALPHA-Q(R183C)
Descriptor:Guanine nucleotide-binding protein G(q) subunit alpha, Regulator of G-protein signaling 2, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Tesmer, J.J.G., Nance, M.R.
Deposit date:2012-04-09
Release date:2013-01-30
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Structural and functional analysis of the regulator of G protein signaling 2-g alpha q complex.
Structure, 21, 2013
2I1J
  • Download 2i1j
  • View 2i1j
Molmil generated image of 2i1j
MOESIN FROM SPODOPTERA FRUGIPERDA AT 2.1 ANGSTROMS RESOLUTION
Descriptor:Moesin, CHLORIDE ION, UREA, ...
Authors:Li, Q., Nance, M.R., Tesmer, J.J.G.
Deposit date:2006-08-14
Release date:2006-12-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Self-masking in an Intact ERM-merlin Protein: An Active Role for the Central alpha-Helical Domain.
J.Mol.Biol., 365, 2007
2RGN
  • Download 2rgn
  • View 2rgn
Molmil generated image of 2rgn
CRYSTAL STRUCTURE OF P63RHOGEF COMPLEX WITH GALPHA-Q AND RHOA
Descriptor:Guanine nucleotide-binding protein G(i) subunit alpha-1,Guanine nucleotide-binding protein G(q) subunit alpha, Rho guanine nucleotide exchange factor 25, Transforming protein RhoA, ...
Authors:Shankaranarayanan, A., Nance, M.R., Tesmer, J.J.G.
Deposit date:2007-10-04
Release date:2008-01-15
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of Galphaq-p63RhoGEF-RhoA complex reveals a pathway for the activation of RhoA by GPCRs.
Science, 318, 2007
3I2F
  • Download 3i2f
  • View 3i2f
Molmil generated image of 3i2f
COCAINE ESTERASE WITH MUTATIONS T172R / G173Q, BOUND TO DTT ADDUCT
Descriptor:Cocaine esterase, CHLORIDE ION, (4S,5S)-4,5-BIS(MERCAPTOMETHYL)-1,3-DIOXOLAN-2-OL, ...
Authors:Tesmer, J.J.G., Nance, M.R.
Deposit date:2009-06-29
Release date:2010-06-16
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural analysis of thermostabilizing mutations of cocaine esterase.
Protein Eng.Des.Sel., 23, 2010
3I2G
  • Download 3i2g
  • View 3i2g
Molmil generated image of 3i2g
COCAINE ESTERASE WITH MUTATION G173Q, BOUND TO DTT ADDUCT
Descriptor:Cocaine esterase, CHLORIDE ION, (4S,5S)-4,5-BIS(MERCAPTOMETHYL)-1,3-DIOXOLAN-2-OL, ...
Authors:Tesmer, J.J.G., Nance, M.R.
Deposit date:2009-06-29
Release date:2010-06-16
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural analysis of thermostabilizing mutations of cocaine esterase.
Protein Eng.Des.Sel., 23, 2010
3I2H
  • Download 3i2h
  • View 3i2h
Molmil generated image of 3i2h
COCAINE ESTERASE WITH MUTATION L169K, BOUND TO DTT ADDUCT
Descriptor:Cocaine esterase, CHLORIDE ION, (4S,5S)-4,5-BIS(MERCAPTOMETHYL)-1,3-DIOXOLAN-2-OL, ...
Authors:Tesmer, J.J.G., Nance, M.R.
Deposit date:2009-06-29
Release date:2010-06-16
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural analysis of thermostabilizing mutations of cocaine esterase.
Protein Eng.Des.Sel., 23, 2010
3I2I
  • Download 3i2i
  • View 3i2i
Molmil generated image of 3i2i
COCAINE ESTERASE WITH MUTATION T172R, BOUND TO DTT ADDUCT
Descriptor:Cocaine esterase, CHLORIDE ION, (4S,5S)-4,5-BIS(MERCAPTOMETHYL)-1,3-DIOXOLAN-2-OL, ...
Authors:Tesmer, J.J.G., Nance, M.R.
Deposit date:2009-06-29
Release date:2010-06-16
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Structural analysis of thermostabilizing mutations of cocaine esterase.
Protein Eng.Des.Sel., 23, 2010
3I2J
  • Download 3i2j
  • View 3i2j
Molmil generated image of 3i2j
COCAINE ESTERASE, WILD TYPE, WITHOUT A LIGAND
Descriptor:Cocaine esterase, CHLORIDE ION, GLYCEROL, ...
Authors:Tesmer, J.J.G., Nance, M.R.
Deposit date:2009-06-29
Release date:2010-06-16
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Structural analysis of thermostabilizing mutations of cocaine esterase.
Protein Eng.Des.Sel., 23, 2010
3I2K
  • Download 3i2k
  • View 3i2k
Molmil generated image of 3i2k
COCAINE ESTERASE, WILD TYPE, BOUND TO A DTT ADDUCT
Descriptor:Cocaine esterase, CHLORIDE ION, (4S,5S)-4,5-BIS(MERCAPTOMETHYL)-1,3-DIOXOLAN-2-OL, ...
Authors:Tesmer, J.J.G., Nance, M.R.
Deposit date:2009-06-29
Release date:2010-06-16
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Structural analysis of thermostabilizing mutations of cocaine esterase.
Protein Eng.Des.Sel., 23, 2010
3IDA
  • Download 3ida
  • View 3ida
Molmil generated image of 3ida
THERMOSTABLE COCAINE ESTERASE WITH MUTATIONS L169K AND G173Q, BOUND TO DTT ADDUCT
Descriptor:Cocaine esterase, CHLORIDE ION, (4S,5S)-4,5-BIS(MERCAPTOMETHYL)-1,3-DIOXOLAN-2-OL, ...
Authors:Tesmer, J.J.G., Nance, M.R.
Deposit date:2009-07-20
Release date:2010-03-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A thermally stable form of bacterial cocaine esterase: a potential therapeutic agent for treatment of cocaine abuse.
Mol.Pharmacol., 77, 2010
3T8O
  • Download 3t8o
  • View 3t8o
Molmil generated image of 3t8o
RHODOPSIN KINASE (GRK1) L166K MUTANT AT 2.5A RESOLUTION
Descriptor:Rhodopsin kinase, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Tesmer, J.J.G., Singh, P., Nance, M.R.
Deposit date:2011-08-01
Release date:2012-06-06
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of a monomeric variant of rhodopsin kinase at 2.5 A resolution.
Acta Crystallogr.,Sect.F, 68, 2012