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5ZYG
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CRYSTAL STRUCTURE OF CERT START DOMAIN IN COMPLEX WITH COMPOUND B5
Descriptor:LIPID-TRANSFER PROTEIN CERT, 2-[4-[3-~{tert}-butyl-5-(2-pyridin-2-ylethyl)phenyl]phenyl]sulfonylethanol
Authors:Suzuki, M., Nakao, N., Ueno, M., Sakai, S., Egawa, D., Hanzawa, H., Kawasaki, S., Kumagai, K., Kobayashi, S., Hanada, K.
Deposit date:2018-05-25
Release date:2019-02-27
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT
Commun Chem, 2019
5ZYH
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CRYSTAL STRUCTURE OF CERT START DOMAIN IN COMPLEX WITH COMPOUND E5
Descriptor:LIPID-TRANSFER PROTEIN CERT, 2-[4-[3-~{tert}-butyl-5-[(1~{R},2~{S})-2-pyridin-2-ylcyclopropyl]phenyl]phenyl]sulfonylethanol
Authors:Suzuki, M., Nakao, N., Ueno, M., Sakai, S., Egawa, D., Hanzawa, H., Kawasaki, S., Kumagai, K., Kobayashi, S., Hanada, K.
Deposit date:2018-05-25
Release date:2019-02-27
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT
Commun Chem, 2019
5ZYI
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CRYSTAL STRUCTURE OF CERT START DOMAIN IN COMPLEX WITH COMPOUND E16
Descriptor:LIPID-TRANSFER PROTEIN CERT, 2-[4-[4-pentyl-3-[(1~{S},2~{R})-2-pyridin-2-ylcyclopropyl]phenyl]phenyl]sulfonylethanol
Authors:Suzuki, M., Nakao, N., Ueno, M., Sakai, S., Egawa, D., Hanzawa, H., Kawasaki, S., Kumagai, K., Kobayashi, S., Hanada, K.
Deposit date:2018-05-25
Release date:2019-02-27
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT
Commun Chem, 2019
5ZYJ
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CRYSTAL STRUCTURE OF CERT START DOMAIN IN COMPLEX WITH COMPOUND E16A
Descriptor:LIPID-TRANSFER PROTEIN CERT, 2-[4-[4-pentyl-3-[(1~{S},2~{R})-2-pyridin-2-ylcyclopropyl]phenyl]phenyl]sulfonylethanol, GLYCEROL
Authors:Suzuki, M., Nakao, N., Ueno, M., Sakai, S., Egawa, D., Hanzawa, H., Kawasaki, S., Kumagai, K., Kobayashi, S., Hanada, K.
Deposit date:2018-05-25
Release date:2019-02-27
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT
Commun Chem, 2019
5ZYK
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CRYSTAL STRUCTURE OF CERT START DOMAIN IN COMPLEX WITH COMPOUND E25
Descriptor:LIPID-TRANSFER PROTEIN CERT, 2-[4-[4-cyclopentyl-3-[(1~{S},2~{R})-2-pyridin-2-ylcyclopropyl]phenyl]phenyl]sulfonylethanol
Authors:Suzuki, M., Nakao, N., Ueno, M., Sakai, S., Egawa, D., Hanzawa, H., Kawasaki, S., Kumagai, K., Kobayashi, S., Hanada, K.
Deposit date:2018-05-25
Release date:2019-02-27
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT
Commun Chem, 2019
5ZYL
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CRYSTAL STRUCTURE OF CERT START DOMAIN IN COMPLEX WITH COMPOUND E25A
Descriptor:LIPID-TRANSFER PROTEIN CERT, 2-[4-[4-cyclopentyl-3-[(1~{S},2~{R})-2-pyridin-2-ylcyclopropyl]phenyl]phenyl]sulfonylethanol, GLYCEROL
Authors:Suzuki, M., Nakao, N., Ueno, M., Sakai, S., Egawa, D., Hanzawa, H., Kawasaki, S., Kumagai, K., Kobayashi, S., Hanada, K.
Deposit date:2018-05-25
Release date:2019-02-27
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT
Commun Chem, 2019
5ZYM
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CRYSTAL STRUCTURE OF CERT START DOMAIN IN COMPLEX WITH COMPOUND E25B
Descriptor:LIPID-TRANSFER PROTEIN CERT, 2-[4-[4-cyclopentyl-3-[(1~{R},2~{S})-2-pyridin-2-ylcyclopropyl]phenyl]phenyl]sulfonylethanol, GLYCEROL
Authors:Suzuki, M., Nakao, N., Ueno, M., Sakai, S., Egawa, D., Hanzawa, H., Kawasaki, S., Kumagai, K., Kobayashi, S., Hanada, K.
Deposit date:2018-05-25
Release date:2019-02-27
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT
Commun Chem, 2019
6IEZ
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CRYSTAL STRUCTURE OF CERT START DOMAIN IN COMPLEX WITH COMPOUND B16
Descriptor:LIPID-TRANSFER PROTEIN CERT, 2-({4'-pentyl-3'-[2-(pyridin-2-yl)ethyl][1,1'-biphenyl]-4-yl}sulfonyl)ethan-1-ol
Authors:Suzuki, M., Nakao, N., Ueno, M., Sakai, S., Egawa, D., Hanzawa, H., Kawasaki, S., Kumagai, K., Kobayashi, S., Hanada, K.
Deposit date:2018-09-18
Release date:2019-02-27
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT
Commun Chem, 2019
6IF0
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CRYSTAL STRUCTURE OF CERT START DOMAIN IN COMPLEX WITH COMPOUND D16
Descriptor:LIPID-TRANSFER PROTEIN CERT, 2-({4'-pentyl-3'-[(Z)-2-(pyridin-2-yl)ethenyl][1,1'-biphenyl]-4-yl}sulfonyl)ethan-1-ol
Authors:Suzuki, M., Nakao, N., Ueno, M., Sakai, S., Egawa, D., Hanzawa, H., Kawasaki, S., Kumagai, K., Kobayashi, S., Hanada, K.
Deposit date:2018-09-18
Release date:2019-02-27
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT
Commun Chem, 2019
6J0O
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CRYSTAL STRUCTURE OF CERT START DOMAIN IN COMPLEX WITH COMPOUND SC1
Descriptor:LIPID-TRANSFER PROTEIN CERT, 2-[4-[2-fluoranyl-5-[3-(6-methylpyridin-2-yl)-1~{H}-pyrazol-4-yl]phenyl]phenyl]sulfonylethanol, UNKNOWN ATOM OR ION
Authors:Suzuki, M., Nakao, N., Ueno, M., Sakai, S., Egawa, D., Hanzawa, H., Kawasaki, S., Kumagai, K., Kobayashi, S., Hanada, K.
Deposit date:2018-12-25
Release date:2019-02-27
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT
Commun Chem, 2019
6J81
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CRYSTAL STRUCTURE OF CERT START DOMAIN IN COMPLEX WITH COMPOUND E14
Descriptor:LIPID-TRANSFER PROTEIN CERT, 2-[4-[4-propyl-3-[(1~{S},2~{R})-2-pyridin-2-ylcyclopropyl]phenyl]phenyl]sulfonylethanol
Authors:Suzuki, M., Nakao, N., Ueno, M., Sakai, S., Egawa, D., Hanzawa, H., Kawasaki, S., Kumagai, K., Kobayashi, S., Hanada, K.
Deposit date:2019-01-18
Release date:2019-02-27
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT
Commun Chem, 2019
3W5E
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CRYSTAL STRUCTURE OF PHOSPHODIESTERASE 4B IN COMPLEX WITH COMPOUND 31E
Descriptor:cAMP-specific 3',5'-cyclic phosphodiesterase 4B, N-tert-butyl-2-{4-[(5,5-dioxido-2-phenyl-7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidin-4-yl)amino]phenyl}acetamide, ZINC ION, ...
Authors:Takahashi, M., Hanzawa, H.
Deposit date:2013-01-28
Release date:2013-05-29
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Identification of the fused bicyclic 4-amino-2-phenylpyrimidine derivatives as novel and potent PDE4 inhibitors
Bioorg.Med.Chem.Lett., 23, 2013
3WD9
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CRYSTAL STRUCTURE OF PHOSPHODIESTERASE 4B IN COMPLEX WITH COMPOUND 10F
Descriptor:cAMP-specific 3',5'-cyclic phosphodiesterase 4B, 4-[(4-{2-[(2,2-dimethylpropyl)amino]-2-oxoethyl}phenyl)amino]-2-phenylpyrimidine-5-carboxamide, ZINC ION, ...
Authors:Takahashi, M., Hanzawa, H.
Deposit date:2013-06-11
Release date:2013-10-23
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Synthesis and biological evaluation of 5-carbamoyl-2-phenylpyrimidine derivatives as novel and potent PDE4 inhibitors
Bioorg.Med.Chem., 21, 2013