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4F1N
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BU of 4f1n by Molmil
Crystal structure of Kluyveromyces polysporus Argonaute with a guide RNA
Descriptor: KpAGO, RNA 5'-R(P*UP*AP*AP*AP*AP*AP*AP*AP*A)-3'
Authors:Nakanishi, K, Weinberg, D.E, Bartel, D.P, Patel, D.J.
Deposit date:2012-05-07
Release date:2012-06-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.187 Å)
Cite:Structure of yeast Argonaute with guide RNA.
Nature, 486, 2012
3HJ7
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BU of 3hj7 by Molmil
Crystal structure of TILS C-terminal domain
Descriptor: CHLORIDE ION, tRNA(Ile)-lysidine synthase
Authors:Nakanishi, K, Bonnefond, L, Kimura, S, Suzuki, T, Ishitani, R, Nureki, O.
Deposit date:2009-05-21
Release date:2009-10-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for translational fidelity ensured by transfer RNA lysidine synthetase.
Nature, 461, 2009
4KXT
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BU of 4kxt by Molmil
Structure of human ARGONAUTE1 in complex with guide RNA
Descriptor: Protein argonaute-1, RNA
Authors:Nakanishi, K, Patel, D.J.
Deposit date:2013-05-28
Release date:2013-07-31
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.294 Å)
Cite:Eukaryote-Specific Insertion Elements Control Human ARGONAUTE Slicer Activity.
Cell Rep, 3, 2013
3A2K
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BU of 3a2k by Molmil
Crystal structure of TilS complexed with tRNA
Descriptor: bacterial tRNA, tRNA(Ile)-lysidine synthase
Authors:Nakanishi, K, Bonnefond, L, Ishitani, R, Nureki, O.
Deposit date:2009-05-23
Release date:2009-10-20
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:Structural basis for translational fidelity ensured by transfer RNA lysidine synthetase.
Nature, 461, 2009
2CSX
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BU of 2csx by Molmil
Crystal structure of Aquifex aeolicus methionyl-tRNA synthetase complexed with tRNA(Met)
Descriptor: Methionyl-tRNA synthetase, RNA (75-MER)
Authors:Nakanishi, K, Ogiso, Y, Nakama, T, Fukai, S, Nureki, O, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-23
Release date:2005-09-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for anticodon recognition by methionyl-tRNA synthetase.
Nat.Struct.Mol.Biol., 12, 2005
2CT8
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BU of 2ct8 by Molmil
Crystal structure of Aquifex aeolicus methionyl-tRNA synthetase complexed with tRNA(Met) and methionyl-adenylate anologue
Descriptor: 5'-O-[(L-METHIONYL)-SULPHAMOYL]ADENOSINE, Methionyl-tRNA synthetase, RNA (74-MER)
Authors:Nakanishi, K, Ogiso, Y, Nakama, T, Fukai, S, Nureki, O, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-23
Release date:2005-09-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for anticodon recognition by methionyl-tRNA synthetase.
Nat.Struct.Mol.Biol., 12, 2005
1WY5
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BU of 1wy5 by Molmil
Crystal structure of isoluecyl-tRNA lysidine synthetase
Descriptor: Hypothetical UPF0072 protein AQ_1887
Authors:Nakanishi, K, Fukai, S, Ikeuchi, Y, Soma, A, Sekine, Y, Suzuki, T, Nureki, O, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-02-06
Release date:2005-05-03
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structural basis for lysidine formation by ATP pyrophosphatase accompanied by a lysine-specific loop and a tRNA-recognition domain.
Proc.Natl.Acad.Sci.Usa, 102, 2005
3RV1
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BU of 3rv1 by Molmil
Crystal structure of the N-terminal and RNase III domains of K. polysporus Dcr1 E224Q mutant
Descriptor: K. polysporus Dcr1
Authors:Nakanishi, K, Weinberg, D.E, Bartel, D.P, Patel, D.J.
Deposit date:2011-05-05
Release date:2011-08-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.975 Å)
Cite:The inside-out mechanism of dicers from budding yeasts.
Cell(Cambridge,Mass.), 146, 2011
3RV0
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BU of 3rv0 by Molmil
Crystal structure of K. polysporus Dcr1 without the C-terminal dsRBD
Descriptor: K. polysporus Dcr1, MAGNESIUM ION
Authors:Nakanishi, K, Weinberg, D.E, Bartel, D.P, Patel, D.J.
Deposit date:2011-05-05
Release date:2011-08-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:The inside-out mechanism of dicers from budding yeasts.
Cell(Cambridge,Mass.), 146, 2011
7KPW
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BU of 7kpw by Molmil
Structure of the H-lobe of yeast CKM
Descriptor: Mediator of RNA polymerase II transcription subunit 12
Authors:Li, Y.C, Chao, T.C, Kim, H.J, Cholko, T, Chen, S.F, Nakanishi, K, Chang, C.E, Murakami, K, Garcia, B.A, Boyer, T.G, Tsai, K.L.
Deposit date:2020-11-12
Release date:2021-01-27
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Structure and noncanonical Cdk8 activation mechanism within an Argonaute-containing Mediator kinase module.
Sci Adv, 7, 2021
7KPV
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BU of 7kpv by Molmil
Structure of kinase and Central lobes of yeast CKM
Descriptor: Mediator of RNA polymerase II transcription subunit 12, Mediator of RNA polymerase II transcription subunit 13, Meiotic mRNA stability protein kinase SSN3, ...
Authors:Li, Y.C, Chao, T.C, Kim, H.J, Cholko, T, Chen, S.F, Nakanishi, K, Chang, C.E, Murakami, K, Garcia, B.A, Boyer, T.G, Tsai, K.L.
Deposit date:2020-11-12
Release date:2021-01-27
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure and noncanonical Cdk8 activation mechanism within an Argonaute-containing Mediator kinase module.
Sci Adv, 7, 2021
7KPX
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BU of 7kpx by Molmil
Structure of the yeast CKM
Descriptor: Mediator of RNA polymerase II transcription subunit 12, Mediator of RNA polymerase II transcription subunit 13, Meiotic mRNA stability protein kinase SSN3, ...
Authors:Li, Y.C, Chao, T.C, Kim, H.J, Cholko, T, Chen, S.F, Nakanishi, K, Chang, C.E, Murakami, K, Garcia, B.A, Boyer, T.G, Tsai, K.L.
Deposit date:2020-11-12
Release date:2021-01-27
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structure and noncanonical Cdk8 activation mechanism within an Argonaute-containing Mediator kinase module.
Sci Adv, 7, 2021
5VXB
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BU of 5vxb by Molmil
Crystal structure of Caulobacter crescentus ProXp-ala at 1.69 Angstrom
Descriptor: ProXp-ala
Authors:Foster, M.P, Musier-Forsyth, K, Nakanishi, K, Ma, X.
Deposit date:2017-05-23
Release date:2017-08-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Conformational and chemical selection by a trans-acting editing domain.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5THE
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BU of 5the by Molmil
Crystal structure of the C-terminal lobe of a budding yeast Argonaute
Descriptor: RNA (5'-R(P*UP*AP*AP*AP*AP*AP*AP*A)-3'), Uncharacterized protein
Authors:Dayeh, D.M, Nakanishi, K.
Deposit date:2016-09-29
Release date:2018-03-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.097 Å)
Cite:Structural and functional analyses reveal the contributions of the C- and N-lobes of Argonaute protein to selectivity of RNA target cleavage.
J. Biol. Chem., 293, 2018
5VM9
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BU of 5vm9 by Molmil
Human Argonaute3 bound to guide RNA
Descriptor: Protein argonaute-3, RNA (5'-R(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*UP*U)-3'), RNA (5'-R(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*UP*U)-3')
Authors:Park, M.S, Nakanishi, K.
Deposit date:2017-04-26
Release date:2017-10-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.28 Å)
Cite:Human Argonaute3 has slicer activity.
Nucleic Acids Res., 45, 2017
1TFO
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BU of 1tfo by Molmil
Ribonuclease from Escherichia coli complexed with its inhibitor protein
Descriptor: Colicin D, Colicin D immunity protein
Authors:Yajima, S, Nakanishi, K, Takahashi, K, Ogawa, T, Kezuka, Y, Hidaka, M, Nonaka, T, Ohsawa, K, Masaki, H.
Deposit date:2004-05-27
Release date:2005-03-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Relation between tRNase activity and the structure of colicin D according to X-ray crystallography
Biochem.Biophys.Res.Commun., 322, 2004
1TFK
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BU of 1tfk by Molmil
Ribonuclease from Escherichia coli complexed with its inhibtor protein
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Colicin D, Colicin D immunity protein
Authors:Yajima, S, Nakanishi, K, Takahashi, K, Ogawa, T, Kezuka, Y, Hidaka, M, Nonaka, T, Ohsawa, K, Masaki, H.
Deposit date:2004-05-27
Release date:2005-03-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Relation between tRNase activity and the structure of colicin D according to X-ray crystallography
Biochem.Biophys.Res.Commun., 322, 2004
6OON
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BU of 6oon by Molmil
Human Argonaute4 bound to guide RNA
Descriptor: Protein argonaute-4, RNA (5'-R(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*UP*U)-3')
Authors:Park, M.S, Brackbill, J.A, Nakanishi, K.
Deposit date:2019-04-23
Release date:2019-07-31
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Multidomain Convergence of Argonaute during RISC Assembly Correlates with the Formation of Internal Water Clusters.
Mol.Cell, 75, 2019
3W4K
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BU of 3w4k by Molmil
Crystal Structure of human DAAO in complex with coumpound 13
Descriptor: 3-hydroxy-6-(2-phenylethyl)pyridazin-4(1H)-one, D-amino-acid oxidase, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Hondo, T, Warizaya, M, Niimi, T, Namatame, I, Yamaguchi, T, Nakanishi, K, Hamajima, T, Harada, K, Sakashita, H, Matsumoto, Y, Orita, M, Watanabe, T, Takeuchi, M.
Deposit date:2013-01-09
Release date:2013-05-29
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:4-Hydroxypyridazin-3(2H)-one Derivatives as Novel d-Amino Acid Oxidase Inhibitors.
J.Med.Chem., 56, 2013
3W4J
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BU of 3w4j by Molmil
Crystal Structure of human DAAO in complex with coumpound 12
Descriptor: 3-hydroxy-5-(2-phenylethyl)pyridin-2(1H)-one, D-amino-acid oxidase, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Hondo, T, Warizaya, M, Niimi, T, Namatame, I, Yamaguchi, T, Nakanishi, K, Hamajima, T, Harada, K, Sakashita, H, Matsumoto, Y, Orita, M, Watanabe, T, Takeuchi, M.
Deposit date:2013-01-09
Release date:2013-05-29
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:4-Hydroxypyridazin-3(2H)-one Derivatives as Novel d-Amino Acid Oxidase Inhibitors.
J.Med.Chem., 56, 2013
3W4I
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BU of 3w4i by Molmil
Crystal Structure of human DAAO in complex with coumpound 8
Descriptor: D-amino-acid oxidase, FLAVIN-ADENINE DINUCLEOTIDE, pyridine-2,3-diol
Authors:Hondo, T, Warizaya, M, Niimi, T, Namatame, I, Yamaguchi, T, Nakanishi, K, Hamajima, T, Harada, K, Sakashita, H, Matsumoto, Y, Orita, M, Watanabe, T, Takeuchi, M.
Deposit date:2013-01-09
Release date:2013-05-29
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:4-Hydroxypyridazin-3(2H)-one Derivatives as Novel d-Amino Acid Oxidase Inhibitors.
J.Med.Chem., 56, 2013
8SQU
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BU of 8squ by Molmil
Monomeric MapSPARTA bound with guide RNA and target DNA hybrid
Descriptor: MAGNESIUM ION, TIR-APAZ, guide RNA, ...
Authors:Shen, Z.F, Yang, X.Y, Fu, T.M.
Deposit date:2023-05-04
Release date:2023-08-23
Last modified:2023-09-20
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Oligomerization-mediated activation of a short prokaryotic Argonaute.
Nature, 621, 2023
8SP3
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BU of 8sp3 by Molmil
Asymmetric dimer of MapSPARTA bound with gRNA/tDNA hybrid
Descriptor: MAGNESIUM ION, TIR-APAZ, guide RNA, ...
Authors:Shen, Z.F, Yang, X.Y, Fu, T.M.
Deposit date:2023-05-01
Release date:2023-08-23
Last modified:2023-09-20
Method:ELECTRON MICROSCOPY (3.52 Å)
Cite:Oligomerization-mediated activation of a short prokaryotic Argonaute.
Nature, 621, 2023
8SP0
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BU of 8sp0 by Molmil
Symmetric dimer of MapSPARTA bound with gRNA/tDNA hybrid
Descriptor: MAGNESIUM ION, TIR-APAZ, guide RNA, ...
Authors:Shen, Z.F, Yang, X.Y, Fu, T.M.
Deposit date:2023-05-01
Release date:2023-08-23
Last modified:2023-09-20
Method:ELECTRON MICROSCOPY (3.33 Å)
Cite:Oligomerization-mediated activation of a short prokaryotic Argonaute.
Nature, 621, 2023
8SPO
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BU of 8spo by Molmil
Tetramerized activation of MapSPARTA bound with NAD+
Descriptor: MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Piwi domain-containing protein, ...
Authors:Shen, Z.F, Yang, X.Y, Fu, T.M.
Deposit date:2023-05-03
Release date:2023-08-23
Last modified:2023-09-20
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:Oligomerization-mediated activation of a short prokaryotic Argonaute.
Nature, 621, 2023

 

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