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6U5S
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BU of 6u5s by Molmil
NTD of GluA2 in complex with CNIH3 - with antagonist ZK200775 - in pseudo-symmetric global conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Nakagawa, T.
Deposit date:2019-08-28
Release date:2019-12-04
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.07 Å)
Cite:Structures of the AMPA receptor in complex with its auxiliary subunit cornichon.
Science, 366, 2019
6PEQ
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BU of 6peq by Molmil
GluA2 in complex with its auxiliary subunit CNIH3 - map LBD-TMD-C3 - with antagonist ZK200775 -without NTD
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHOLESTEROL, Glutamate receptor 2, ...
Authors:Nakagawa, T.
Deposit date:2019-06-20
Release date:2019-12-04
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:Structures of the AMPA receptor in complex with its auxiliary subunit cornichon.
Science, 366, 2019
6UCB
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BU of 6ucb by Molmil
GluA2 in complex with its auxiliary subunit CNIH3 - with antagonist ZK200775, LBD, TMD, CNIH3, and lipids
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHOLESTEROL, Glutamate receptor 2, ...
Authors:Nakagawa, T.
Deposit date:2019-09-15
Release date:2019-12-04
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Structures of the AMPA receptor in complex with its auxiliary subunit cornichon.
Science, 366, 2019
6UD8
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BU of 6ud8 by Molmil
GluA2 in complex with its auxiliary subunit CNIH3 - with antagonist ZK200775
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHOLESTEROL, Glutamate receptor 2, ...
Authors:Nakagawa, T.
Deposit date:2019-09-18
Release date:2019-12-04
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structures of the AMPA receptor in complex with its auxiliary subunit cornichon.
Science, 366, 2019
6U6I
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BU of 6u6i by Molmil
NTD of GluA2 in complex with CNIH3 - with antagonist ZK200775 - in asymmetric global conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2, ...
Authors:Nakagawa, T.
Deposit date:2019-08-29
Release date:2019-12-04
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Structures of the AMPA receptor in complex with its auxiliary subunit cornichon.
Science, 366, 2019
6UD4
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BU of 6ud4 by Molmil
GluA2 in complex with its auxiliary subunit CNIH3 in AS map II - (LBD-TMD-C3(AS) II)- with antagonist ZK200775, without NTD
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHOLESTEROL, Glutamate receptor 2, ...
Authors:Nakagawa, T.
Deposit date:2019-09-18
Release date:2019-12-04
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structures of the AMPA receptor in complex with its auxiliary subunit cornichon.
Science, 366, 2019
8FQ5
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BU of 8fq5 by Molmil
GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 140mM NMDG, 330uM CTZ, and 100mM L-glutamate (Open-Na110)
Descriptor: CHLORIDE ION, Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
Authors:Nakagawa, T.
Deposit date:2023-01-05
Release date:2024-02-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.34 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 2024
8FQ6
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BU of 8fq6 by Molmil
LBD of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 150mM CaCl2, 330uM CTZ, and 100mM L-glutamate (Open-Ca150)
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2
Authors:Nakagawa, T.
Deposit date:2023-01-05
Release date:2024-02-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.14 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 2024
8FQ1
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BU of 8fq1 by Molmil
GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 150mM CaCl2, 330uM CTZ, and 100mM L-glutamate (Open-Ca150)
Descriptor: CALCIUM ION, Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
Authors:Nakagawa, T.
Deposit date:2023-01-05
Release date:2024-02-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (5.59 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 2024
8FP4
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BU of 8fp4 by Molmil
GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 500mM NaCl, 330uM CTZ, and 100mM glutamate (Open-Na610)
Descriptor: CHLORIDE ION, Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
Authors:Nakagawa, T.
Deposit date:2023-01-04
Release date:2024-02-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 2024
8FQ8
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BU of 8fq8 by Molmil
LBD conformation 1 (LBDconf1) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 140mM NMDG, 330uM CTZ, and 100mM L-glutamate (Open-Na110)
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2
Authors:Nakagawa, T.
Deposit date:2023-01-05
Release date:2024-02-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.11 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 2024
8FR0
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BU of 8fr0 by Molmil
LBD conformation 3 (LBDconf3) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 150mM NaCl, 330uM CTZ, and 100mM glutamate (Open-Na260)
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2
Authors:Nakagawa, T.
Deposit date:2023-01-06
Release date:2024-02-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 2024
8FPG
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BU of 8fpg by Molmil
GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100uM CNQX (Closed-CaNaMg)
Descriptor: CHLORIDE ION, Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
Authors:Nakagawa, T.
Deposit date:2023-01-04
Release date:2024-02-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.32 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 2024
8FPH
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BU of 8fph by Molmil
Conformation 2 of the ligand binding domain (LBDconf2) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100mM glutamate (Open-CaNaMg)
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2
Authors:Nakagawa, T.
Deposit date:2023-01-04
Release date:2024-02-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.14 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 2024
8FPK
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BU of 8fpk by Molmil
LBD conformation 1 of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100uM CNQX (Closed-CaNaMg)
Descriptor: 6-(aminomethyl)-7-nitro-1,4-dihydroquinoxaline-2,3-dione, CYCLOTHIAZIDE, Glutamate receptor 2
Authors:Nakagawa, T.
Deposit date:2023-01-04
Release date:2024-02-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 2024
8FPS
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BU of 8fps by Molmil
GluA2 flip Q isoform N619K mutant of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100mM glutamate (Open-CaNaMg/N619K)
Descriptor: CHLORIDE ION, Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
Authors:Nakagawa, T.
Deposit date:2023-01-05
Release date:2024-02-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.38 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 2024
8FQB
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BU of 8fqb by Molmil
GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 10mM CaCl2, 140mM NMDG, 330uM CTZ, and 100mM L-glutamate (Open-Ca10)
Descriptor: CALCIUM ION, CHLORIDE ION, Glutamate receptor 2, ...
Authors:Nakagawa, T.
Deposit date:2023-01-05
Release date:2024-02-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.36 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 2024
8FQE
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BU of 8fqe by Molmil
LBD conformation 2 (LBDconf2) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 10mM CaCl2, 140mM NMDG, 330uM CTZ, and 100mM L-glutamate (Open-Ca10)
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2
Authors:Nakagawa, T.
Deposit date:2023-01-06
Release date:2024-02-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.14 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 2024
8FP9
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BU of 8fp9 by Molmil
GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100mM glutamate (Open-CaNaMg)
Descriptor: CALCIUM ION, CHLORIDE ION, Glutamate receptor 2, ...
Authors:Nakagawa, T.
Deposit date:2023-01-04
Release date:2024-02-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.44 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 2024
8FPL
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BU of 8fpl by Molmil
LBD conformation 2 (LBDconf2) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100uM CNQX (Closed-CaNaMg)
Descriptor: 6-(aminomethyl)-7-nitro-1,4-dihydroquinoxaline-2,3-dione, CYCLOTHIAZIDE, Glutamate receptor 2
Authors:Nakagawa, T.
Deposit date:2023-01-04
Release date:2024-02-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.81 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 2024
8FQ3
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BU of 8fq3 by Molmil
LBD conformation 2 (LBDconf2) of GluA2 flip Q isoform N619K mutant of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100mM glutamate (Open-CaNaMg/N619K)
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2
Authors:Nakagawa, T.
Deposit date:2023-01-05
Release date:2024-02-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 2024
8FQF
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BU of 8fqf by Molmil
GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 150mM NaCl, 330uM CTZ, and 100mM glutamate (Open-Na260)
Descriptor: CHLORIDE ION, Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
Authors:Nakagawa, T.
Deposit date:2023-01-06
Release date:2024-02-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.29 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 2024
8FQG
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BU of 8fqg by Molmil
LBD conformation 1 (LBDconf1) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 150mM NaCl, 330uM CTZ, and 100mM glutamate (Open-Na260)
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2
Authors:Nakagawa, T.
Deposit date:2023-01-06
Release date:2024-02-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.01 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 2024
8FPC
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BU of 8fpc by Molmil
Conformation 1 of the ligand binding domain (LBDconf1) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100mM glutamate (Open-CaNaMg)
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2
Authors:Nakagawa, T.
Deposit date:2023-01-04
Release date:2024-02-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.78 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 2024
8FQD
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BU of 8fqd by Molmil
LBD conformation 1 (LBDconf1) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 10mM CaCl2, 140mM NMDG, 330uM CTZ, and 100mM L-glutamate (Open-Ca10)
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2
Authors:Nakagawa, T.
Deposit date:2023-01-06
Release date:2024-02-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.01 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 2024

 

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