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1F2R
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BU of 1f2r by Molmil
NMR STRUCTURE OF THE HETERODIMERIC COMPLEX BETWEEN CAD DOMAINS OF CAD AND ICAD
Descriptor: CASPASE-ACTIVATED DNASE, INHIBITOR OF CASPASE-ACTIVATED DNASE
Authors:Otomo, T, Sakahira, H, Uegaki, K, Nagata, S, Yamazaki, T.
Deposit date:2000-05-29
Release date:2000-06-08
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Structure of the heterodimeric complex between CAD domains of CAD and ICAD.
Nat.Struct.Biol., 7, 2000
8HLB
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BU of 8hlb by Molmil
Cryo-EM structure of biparatopic antibody Bp109-92 in complex with TNFR2
Descriptor: TR109 heavy chain, TR109 light chain, TR92 heavy chain, ...
Authors:Akiba, H, Fujita, J, Ise, T, Nishiyama, K, Miyata, T, Kato, T, Namba, K, Ohno, H, Kamada, H, Nagata, S, Tsumoto, K.
Deposit date:2022-11-29
Release date:2023-10-04
Method:ELECTRON MICROSCOPY (3.63 Å)
Cite:Development of a 1:1-binding biparatopic anti-TNFR2 antagonist by reducing signaling activity through epitope selection.
Commun Biol, 6, 2023
7DCE
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BU of 7dce by Molmil
Cryo-EM structure of human XKR8-basigin complex bound to Fab fragment
Descriptor: 1,2-DILINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Heavy chain of Fab fragment, Isoform 2 of Basigin, ...
Authors:Sakuragi, T, Kanai, R, Tsutsumi, A, Narita, H, Onishi, E, Miyazaki, T, Baba, T, Nakagawa, A, Kikkawa, M, Toyoshima, C, Nagata, S.
Deposit date:2020-10-26
Release date:2021-10-20
Last modified:2024-01-24
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:The tertiary structure of the human Xkr8-Basigin complex that scrambles phospholipids at plasma membranes.
Nat.Struct.Mol.Biol., 28, 2021
7DAA
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BU of 7daa by Molmil
Crystal structure of basigin complexed with anti-basigin Fab fragment
Descriptor: CADMIUM ION, Heavy chain of antibody Fab fragment, Isoform 2 of Basigin, ...
Authors:Sakuragi, T, Kanai, R, Narita, H, Onishi, E, Miyazaki, T, Baba, T, Nakagawa, A, Toyoshima, C, Nagata, S.
Deposit date:2020-10-16
Release date:2021-10-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:The tertiary structure of the human Xkr8-Basigin complex that scrambles phospholipids at plasma membranes.
Nat.Struct.Mol.Biol., 28, 2021
7D9Z
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BU of 7d9z by Molmil
Crystal structure of anti-basigin Fab fragment
Descriptor: 1,2-ETHANEDIOL, CITRATE ANION, Heavy chain of antibody Fab fragment, ...
Authors:Sakuragi, T, Kanai, R, Narita, H, Onishi, E, Miyazaki, T, Baba, T, Nakagawa, A, Toyoshima, C, Nagata, S.
Deposit date:2020-10-14
Release date:2021-10-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.123 Å)
Cite:The tertiary structure of the human Xkr8-Basigin complex that scrambles phospholipids at plasma membranes.
Nat.Struct.Mol.Biol., 28, 2021
1C9F
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BU of 1c9f by Molmil
NMR STRUCTURE OF THE CAD DOMAIN OF CASPASE-ACTIVATED DNASE
Descriptor: CASPASE-ACTIVATED DNASE
Authors:Yamazaki, T, Uegaki, K.
Deposit date:1999-08-02
Release date:2000-02-16
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Structure of the CAD domain of caspase-activated DNase and interaction with the CAD domain of its inhibitor.
J.Mol.Biol., 297, 2000
8XEJ
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BU of 8xej by Molmil
Cryo-EM structure of human XKR8-basigin complex in lipid nanodisc
Descriptor: 1,2-DILINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Fab heavy chain, Fab light chain, ...
Authors:Sakuragi, T.S, Kanai, R.K, Kikkawa, M.K, Toyoshima, C.T, Nagata, S.N.
Deposit date:2023-12-12
Release date:2024-02-28
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.66 Å)
Cite:The role of the C-terminal tail region as a plug to regulate XKR8 lipid scramblase.
J.Biol.Chem., 300, 2024
7BSS
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BU of 7bss by Molmil
Cryo-EM structure of a human ATP11C-CDC50A flippase in E1AlF state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ATP11C, CDC50A, ...
Authors:Abe, K, Nishizawa, T, Nakanishi, H.
Deposit date:2020-03-31
Release date:2020-09-30
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Transport Cycle of Plasma Membrane Flippase ATP11C by Cryo-EM.
Cell Rep, 32, 2020
7BSQ
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BU of 7bsq by Molmil
Cryo-EM structure of a human ATP11C-CDC50A flippase in E1AlF-ADP state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, ATP11C, ...
Authors:Abe, K, Nishizawa, T, Nakanishi, H.
Deposit date:2020-03-31
Release date:2020-09-30
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Transport Cycle of Plasma Membrane Flippase ATP11C by Cryo-EM.
Cell Rep, 32, 2020
7BSU
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BU of 7bsu by Molmil
Cryo-EM structure of a human ATP11C-CDC50A flippase in PtdSer-bound E2BeF state
Descriptor: 1-deoxy-alpha-D-mannopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ATP11C, ...
Authors:Abe, K, Nishizawa, T, Nakanishi, H.
Deposit date:2020-03-31
Release date:2020-09-30
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Transport Cycle of Plasma Membrane Flippase ATP11C by Cryo-EM.
Cell Rep, 32, 2020
7BSP
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BU of 7bsp by Molmil
Cryo-EM structure of a human ATP11C-CDC50A flippase in E1-AMPPCP state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, ATP11C, ...
Authors:Abe, K, Nishizawa, T, Nakanishi, H.
Deposit date:2020-03-31
Release date:2020-09-30
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Transport Cycle of Plasma Membrane Flippase ATP11C by Cryo-EM.
Cell Rep, 32, 2020
7BSV
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BU of 7bsv by Molmil
Cryo-EM structure of a human ATP11C-CDC50A flippase in PtdSer-occluded E2-AlF state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ATP11C, CDC50A, ...
Authors:Abe, K, Nishizawa, T, Nakanishi, H.
Deposit date:2020-03-31
Release date:2020-09-30
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Transport Cycle of Plasma Membrane Flippase ATP11C by Cryo-EM.
Cell Rep, 32, 2020
7BSW
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BU of 7bsw by Molmil
Cryo-EM structure of a human ATP11C-CDC50A flippase in PtdEtn-occluded E2-AlF state
Descriptor: 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ATP11C, ...
Authors:Abe, K, Nishizawa, T, Nakanishi, H.
Deposit date:2020-03-31
Release date:2020-09-30
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Transport Cycle of Plasma Membrane Flippase ATP11C by Cryo-EM.
Cell Rep, 32, 2020
6LKN
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BU of 6lkn by Molmil
Crystal structure of ATP11C-CDC50A in PtdSer-bound E2P state
Descriptor: 1-deoxy-alpha-D-mannopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Cell cycle control protein 50A, ...
Authors:Abe, K, Irie, K, Nakanishi, H, Hasegawa, K.
Deposit date:2019-12-19
Release date:2020-06-10
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Crystal structure of a human plasma membrane phospholipid flippase.
J.Biol.Chem., 295, 2020
1HMK
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BU of 1hmk by Molmil
RECOMBINANT GOAT ALPHA-LACTALBUMIN
Descriptor: CALCIUM ION, PROTEIN (ALPHA-LACTALBUMIN)
Authors:Horii, K, Matsushima, M, Tsumoto, K, Kumagai, I.
Deposit date:1998-11-26
Release date:1999-11-26
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Effect of the extra n-terminal methionine residue on the stability and folding of recombinant alpha-lactalbumin expressed in Escherichia coli.
J.Mol.Biol., 285, 1999
2TYS
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BU of 2tys by Molmil
CRYSTAL STRUCTURES OF MUTANT (BETAK87T) TRYPTOPHAN SYNTHASE ALPHA2 BETA2 COMPLEX WITH LIGANDS BOUND TO THE ACTIVE SITES OF THE ALPHA AND BETA SUBUNITS REVEAL LIGAND-INDUCED CONFORMATIONAL CHANGES
Descriptor: SODIUM ION, TRYPTOPHAN SYNTHASE, [3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-L-TRYPTOPHANE
Authors:Rhee, S, Parris, K.D, Hyde, C.C, Ahmed, S.A, Miles, E.W, Davies, D.R.
Deposit date:1997-01-08
Release date:1997-04-01
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of a mutant (betaK87T) tryptophan synthase alpha2beta2 complex with ligands bound to the active sites of the alpha- and beta-subunits reveal ligand-induced conformational changes.
Biochemistry, 36, 1997
2TSY
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BU of 2tsy by Molmil
CRYSTAL STRUCTURES OF MUTANT (BETAK87T) TRYPTOPHAN SYNTHASE ALPHA2 BETA2 COMPLEX WITH LIGANDS BOUND TO THE ACTIVE SITES OF THE ALPHA AND BETA SUBUNITS REVEAL LIGAND-INDUCED CONFORMATIONAL CHANGES
Descriptor: SN-GLYCEROL-3-PHOSPHATE, SODIUM ION, TRYPTOPHAN SYNTHASE, ...
Authors:Rhee, S, Parris, K.D, Hyde, C.C, Ahmed, S.A, Miles, E.W, Davies, D.R.
Deposit date:1997-01-03
Release date:1997-04-01
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of a mutant (betaK87T) tryptophan synthase alpha2beta2 complex with ligands bound to the active sites of the alpha- and beta-subunits reveal ligand-induced conformational changes.
Biochemistry, 36, 1997
2TRS
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BU of 2trs by Molmil
CRYSTAL STRUCTURES OF MUTANT (BETAK87T) TRYPTOPHAN SYNTHASE ALPHA2 BETA2 COMPLEX WITH LIGANDS BOUND TO THE ACTIVE SITES OF THE ALPHA AND BETA SUBUNITS REVEAL LIGAND-INDUCED CONFORMATIONAL CHANGES
Descriptor: INDOLE-3-PROPANOL PHOSPHATE, SODIUM ION, TRYPTOPHAN SYNTHASE, ...
Authors:Rhee, S, Parris, K.D, Hyde, C.C, Ahmed, S.A, Miles, E.W, Davies, D.R.
Deposit date:1997-01-07
Release date:1997-04-01
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Crystal structures of a mutant (betaK87T) tryptophan synthase alpha2beta2 complex with ligands bound to the active sites of the alpha- and beta-subunits reveal ligand-induced conformational changes.
Biochemistry, 36, 1997
1UBS
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BU of 1ubs by Molmil
TRYPTOPHAN SYNTHASE (E.C.4.2.1.20) WITH A MUTATION OF LYS 87->THR IN THE B SUBUNIT AND IN THE PRESENCE OF LIGAND L-SERINE
Descriptor: PYRIDOXAL-5'-PHOSPHATE, SERINE, SODIUM ION, ...
Authors:Rhee, S, Parris, K, Ahmed, S.A, Miles, E.W, Davies, D.R.
Deposit date:1995-12-14
Release date:1996-03-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of a mutant (betaK87T) tryptophan synthase alpha2beta2 complex with ligands bound to the active sites of the alpha- and beta-subunits reveal ligand-induced conformational changes.
Biochemistry, 36, 1997
1FKQ
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BU of 1fkq by Molmil
RECOMBINANT GOAT ALPHA-LACTALBUMIN T29V
Descriptor: ALPHA-LACTALBUMIN, CALCIUM ION
Authors:Horii, K, Matsushima, M, Tsumoto, K, Kumagai, I.
Deposit date:2000-08-10
Release date:2001-02-14
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Contribution of Thr29 to the thermodynamic stability of goat alpha-lactalbumin as determined by experimental and theoretical approaches.
Proteins, 45, 2001
1FKV
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BU of 1fkv by Molmil
RECOMBINANT GOAT ALPHA-LACTALBUMIN T29I
Descriptor: ALPHA-LACTALBUMIN, CALCIUM ION
Authors:Horii, K, Matsushima, M, Tsumoto, K, Kumagai, I.
Deposit date:2000-08-10
Release date:2001-02-14
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Contribution of Thr29 to the thermodynamic stability of goat alpha-lactalbumin as determined by experimental and theoretical approaches.
Proteins, 45, 2001

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