Author results

1UEA
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MMP-3/TIMP-1 COMPLEX
Descriptor:MATRIX METALLOPROTEINASE-3, TISSUE INHIBITOR OF METALLOPROTEINASE-1, ZINC ION, ...
Authors:Bode, W., Maskos, K., Gomis-Rueth, F.-X., Nagase, H.
Deposit date:1997-06-06
Release date:1998-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mechanism of inhibition of the human matrix metalloproteinase stromelysin-1 by TIMP-1.
Nature, 389, 1997
1IRI
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CRYSTAL STRUCTURE OF HUMAN AUTOCRINE MOTILITY FACTOR COMPLEXED WITH AN INHIBITOR
Descriptor:autocrine motility factor, ERYTHOSE-4-PHOSPHATE
Authors:Tanaka, N., Haga, A., Uemura, H., Akiyama, H., Funasaka, T., Nagase, H., Raz, A., Nakamura, K.T.
Deposit date:2001-10-08
Release date:2002-06-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Inhibition mechanism of cytokine activity of human autocrine motility factor examined by crystal structure analyses and site-directed mutagenesis studies.
J.Mol.Biol., 318, 2002
1JIQ
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CRYSTAL STRUCTURE OF HUMAN AUTOCRINE MOTILITY FACTOR
Descriptor:autocrine motility factor
Authors:Tanaka, N., Haga, A., Uemura, H., Akiyama, H., Funasaka, T., Nagase, H., Raz, A., Nakamura, K.T.
Deposit date:2001-07-02
Release date:2002-06-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Inhibition mechanism of cytokine activity of human autocrine motility factor examined by crystal structure analyses and site-directed mutagenesis studies.
J.Mol.Biol., 318, 2002
1SU3
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X-RAY STRUCTURE OF HUMAN PROMMP-1: NEW INSIGHTS INTO COLLAGENASE ACTION
Descriptor:Interstitial collagenase, CALCIUM ION, CHLORIDE ION, ...
Authors:Jozic, D., Bourenkov, G., Lim, N.H., Nagase, H., Bode, W., Maskos, K., Structural Proteomics in Europe (SPINE)
Deposit date:2004-03-26
Release date:2004-12-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:X-ray structure of human proMMP-1: new insights into procollagenase activation and collagen binding.
J.Biol.Chem., 280, 2005
2CLT
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CRYSTAL STRUCTURE OF THE ACTIVE FORM (FULL-LENGTH) OF HUMAN FIBROBLAST COLLAGENASE.
Descriptor:INTERSTITIAL COLLAGENASE, CALCIUM ION, ZINC ION
Authors:Iyer, S., Visse, R., Nagase, H., Acharya, K.R.
Deposit date:2006-04-29
Release date:2006-08-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Crystal Structure of an Active Form of Human Mmp-1.
J.Mol.Biol., 362, 2006
2CVP
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CRYSTAL STRUCTURE OF MOUSE AMF
Descriptor:Glucose-6-phosphate isomerase, ACETATE ION, GLYCEROL
Authors:Tanaka, N., Haga, A., Naba, N., Shiraiwa, K., Kusakabe, Y., Hashimoto, K., Funasaka, T., Nagase, H., Raz, A., Nakamura, K.T.
Deposit date:2005-06-10
Release date:2006-05-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structures of mouse autocrine motility factor in complex with carbohydrate phosphate inhibitors provide insight into structure-activity relationship of the inhibitors
J.Mol.Biol., 356, 2006
2CXN
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CRYSTAL STRUCTURE OF MOUSE AMF / PHOSPHATE COMPLEX
Descriptor:Glucose-6-phosphate isomerase, PHOSPHATE ION, GLYCEROL
Authors:Tanaka, N., Haga, A., Naba, N., Shiraiwa, K., Kusakabe, Y., Hashimoto, K., Funasaka, T., Nagase, H., Raz, A., Nakamura, K.T.
Deposit date:2005-06-30
Release date:2006-05-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structures of mouse autocrine motility factor in complex with carbohydrate phosphate inhibitors provide insight into structure-activity relationship of the inhibitors
J.Mol.Biol., 356, 2006
2CXO
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CRYSTAL STRUCTURE OF MOUSE AMF / E4P COMPLEX
Descriptor:Glucose-6-phosphate isomerase, D-4-PHOSPHOERYTHRONIC ACID, GLYCEROL
Authors:Tanaka, N., Haga, A., Naba, N., Shiraiwa, K., Kusakabe, Y., Hashimoto, K., Funasaka, T., Nagase, H., Raz, A., Nakamura, K.T.
Deposit date:2005-06-30
Release date:2006-05-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structures of mouse autocrine motility factor in complex with carbohydrate phosphate inhibitors provide insight into structure-activity relationship of the inhibitors
J.Mol.Biol., 356, 2006
2CXP
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CRYSTAL STRUCTURE OF MOUSE AMF / A5P COMPLEX
Descriptor:Glucose-6-phosphate isomerase, ARABINOSE-5-PHOSPHATE, GLYCEROL
Authors:Tanaka, N., Haga, A., Naba, N., Shiraiwa, K., Kusakabe, Y., Hashimoto, K., Funasaka, T., Nagase, H., Raz, A., Nakamura, K.T.
Deposit date:2005-06-30
Release date:2006-05-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of mouse autocrine motility factor in complex with carbohydrate phosphate inhibitors provide insight into structure-activity relationship of the inhibitors
J.Mol.Biol., 356, 2006
2CXQ
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CRYSTAL STRUCTURE OF MOUSE AMF / S6P COMPLEX
Descriptor:Glucose-6-phosphate isomerase, D-SORBITOL-6-PHOSPHATE, GLYCEROL
Authors:Tanaka, N., Haga, A., Naba, N., Shiraiwa, K., Kusakabe, Y., Hashimoto, K., Funasaka, T., Nagase, H., Raz, A., Nakamura, K.T.
Deposit date:2005-06-30
Release date:2006-05-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structures of mouse autocrine motility factor in complex with carbohydrate phosphate inhibitors provide insight into structure-activity relationship of the inhibitors
J.Mol.Biol., 356, 2006
2CXR
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CRYSTAL STRUCTURE OF MOUSE AMF / 6PG COMPLEX
Descriptor:Glucose-6-phosphate isomerase, 6-PHOSPHOGLUCONIC ACID, GLYCEROL
Authors:Tanaka, N., Haga, A., Naba, N., Shiraiwa, K., Kusakabe, Y., Hashimoto, K., Funasaka, T., Nagase, H., Raz, A., Nakamura, K.T.
Deposit date:2005-06-30
Release date:2006-05-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of mouse autocrine motility factor in complex with carbohydrate phosphate inhibitors provide insight into structure-activity relationship of the inhibitors
J.Mol.Biol., 356, 2006
2CXS
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CRYSTAL STRUCTURE OF MOUSE AMF / F6P COMPLEX
Descriptor:Glucose-6-phosphate isomerase, FRUCTOSE-6-PHOSPHATE, GLYCEROL
Authors:Tanaka, N., Haga, A., Naba, N., Shiraiwa, K., Kusakabe, Y., Hashimoto, K., Funasaka, T., Nagase, H., Raz, A., Nakamura, K.T.
Deposit date:2005-06-30
Release date:2006-05-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structures of mouse autocrine motility factor in complex with carbohydrate phosphate inhibitors provide insight into structure-activity relationship of the inhibitors
J.Mol.Biol., 356, 2006
2CXT
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CRYSTAL STRUCTURE OF MOUSE AMF / F6P COMPLEX
Descriptor:Glucose-6-phosphate isomerase, FRUCTOSE-6-PHOSPHATE, GLYCEROL
Authors:Tanaka, N., Haga, A., Naba, N., Shiraiwa, K., Kusakabe, Y., Hashimoto, K., Funasaka, T., Nagase, H., Raz, A., Nakamura, K.T.
Deposit date:2005-06-30
Release date:2006-05-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structures of mouse autocrine motility factor in complex with carbohydrate phosphate inhibitors provide insight into structure-activity relationship of the inhibitors
J.Mol.Biol., 356, 2006
2CXU
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CRYSTAL STRUCTURE OF MOUSE AMF / M6P COMPLEX
Descriptor:Glucose-6-phosphate isomerase, PHOSPHATE ION, GLYCEROL
Authors:Tanaka, N., Haga, A., Naba, N., Shiraiwa, K., Kusakabe, Y., Hashimoto, K., Funasaka, T., Nagase, H., Raz, A., Nakamura, K.T.
Deposit date:2005-06-30
Release date:2006-05-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structures of mouse autocrine motility factor in complex with carbohydrate phosphate inhibitors provide insight into structure-activity relationship of the inhibitors
J.Mol.Biol., 356, 2006
3WJ4
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CRYSTAL STRUCTURE OF PPARGAMMA LIGAND BINDING DOMAIN IN COMPLEX WITH TRIBUTYLTIN
Descriptor:Peroxisome proliferator-activated receptor gamma, tributylstannanyl
Authors:Harada, S., Hiromori, Y., Fukakusa, S., Kawahara, K., Nakamura, S., Noda, M., Uchiyama, S., Fukui, K., Nishikawa, J., Nagase, H., Kobayashi, Y., Ohkubo, T., Yoshida, T., Nakanishi, T.
Deposit date:2013-10-04
Release date:2014-10-15
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural basis for PPARgamma transactivation by endocrine disrupting organotin compounds
To be Published
3WJ5
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CRYSTAL STRUCTURE OF PPARGAMMA LIGAND BINDING DOMAIN IN COMPLEX WITH TRIPHENYLTIN
Descriptor:Peroxisome proliferator-activated receptor gamma, triphenylstannanyl
Authors:Harada, S., Hiromori, Y., Fukakusa, S., Kawahara, K., Nakamura, S., Noda, M., Uchiyama, S., Fukui, K., Nishikawa, J., Nagase, H., Kobayashi, Y., Ohkubo, T., Yoshida, T., Nakanishi, T.
Deposit date:2013-10-04
Release date:2014-10-15
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structural basis for PPARgamma transactivation by endocrine disrupting organotin compounds
To be Published
4AUO
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CRYSTAL STRUCTURE OF MMP-1(E200A) IN COMPLEX WITH A TRIPLE-HELICAL COLLAGEN PEPTIDE
Descriptor:INTERSTITIAL COLLAGENASE, TRIPLE-HELICAL COLLAGEN PEPTIDE, CALCIUM ION, ...
Authors:Manka, S.W., Carafoli, F., Visse, R., Bihan, D., Raynal, N., Farndale, R.W., Murphy, G., Enghild, J.J., Hohenester, E., Nagase, H.
Deposit date:2012-05-18
Release date:2012-07-11
Last modified:2012-08-15
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Insights Into Triple-Helical Collagen Cleavage by Matrix Metalloproteinase 1
Proc.Natl.Acad.Sci.USA, 109, 2012
4FU4
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HUMAN COLLAGENASE 3 (MMP-13) WITH PEPTIDE FROM PRO-DOMAIN
Descriptor:Collagenase 3, pro-domain peptide, ZINC ION, ...
Authors:Stura, E.A., Vera, L., Visse, R., Nagase, H., Dive, V.
Deposit date:2012-06-28
Release date:2013-08-21
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (2.849 Å)
Cite:Crystal structure of full-length human collagenase 3 (MMP-13) with peptides in the active site defines exosites in the catalytic domain.
Faseb J., 27, 2013
4FVL
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HUMAN COLLAGENASE 3 (MMP-13) FULL FORM WITH PEPTIDES FROM PRO-DOMAIN
Descriptor:Collagenase 3, pro-domain peptide, ZINC ION, ...
Authors:Stura, E.A., Vera, L., Visse, R., Nagase, H., Dive, V.
Deposit date:2012-06-29
Release date:2013-08-21
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (2.436 Å)
Cite:Crystal structure of full-length human collagenase 3 (MMP-13) with peptides in the active site defines exosites in the catalytic domain.
Faseb J., 27, 2013
4G0D
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HUMAN COLLAGENASE 3 (MMP-13) FULL FORM WITH PEPTIDES FROM PRO-DOMAIN
Descriptor:Collagenase 3, pro-domain peptide, ZINC ION, ...
Authors:Stura, E.A., Vera, L., Visse, R., Nagase, H., Dive, V.
Deposit date:2012-07-09
Release date:2013-08-21
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Crystal structure of full-length human collagenase 3 (MMP-13) with peptides in the active site defines exosites in the catalytic domain.
Faseb J., 27, 2013
3C7X
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HEMOPEXIN-LIKE DOMAIN OF MATRIX METALLOPROTEINASE 14
Descriptor:Matrix metalloproteinase-14, SODIUM ION, CHLORIDE ION
Authors:Tochowicz, A., Itoh, Y., Maskos, K., Bode, W., Goettig, P.
Deposit date:2008-02-08
Release date:2009-02-10
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The dimer interface of the membrane type 1 matrix metalloproteinase hemopexin domain: crystal structure and biological functions
J.Biol.Chem., 286, 2011
3BA0
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CRYSTAL STRUCTURE OF FULL-LENGTH HUMAN MMP-12
Descriptor:Macrophage metalloelastase, ZINC ION, CALCIUM ION, ...
Authors:Bertini, I., Calderone, V., Fragai, M., Jaiswal, R., Luchinat, C., Melikian, M., Myonas, E., Svergun, D.I.
Deposit date:2007-11-07
Release date:2008-07-29
Last modified:2018-07-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:Evidence of reciprocal reorientation of the catalytic and hemopexin-like domains of full-length MMP-12.
J.Am.Chem.Soc., 130, 2008