Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
2TMP
DownloadVisualize
BU of 2tmp by Molmil
N-TERMINAL DOMAIN OF TISSUE INHIBITOR OF METALLOPROTEINASE-2 (N-TIMP-2), NMR, 49 STRUCTURES
Descriptor: TISSUE INHIBITOR OF METALLOPROTEINASES-2
Authors:Muskett, F.W, Frenkiel, T.A, Feeney, J, Freedman, R.B, Carr, M.D, Williamson, R.A.
Deposit date:1998-05-26
Release date:1998-12-09
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:High resolution structure of the N-terminal domain of tissue inhibitor of metalloproteinases-2 and characterization of its interaction site with matrix metalloproteinase-3.
J.Biol.Chem., 273, 1998
1PE3
DownloadVisualize
BU of 1pe3 by Molmil
Solution structure of the disulphide-linked dimer of human intestinal trefoil factor (TFF3)
Descriptor: Trefoil factor 3
Authors:Muskett, F.W, May, F.E, Westley, B.R, Feeney, J.
Deposit date:2003-05-21
Release date:2004-03-09
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of the disulfide-linked dimer of human intestinal trefoil factor (TFF3): the intermolecular orientation and interactions are markedly different from those of other dimeric trefoil proteins.
Biochemistry, 42, 2003
1HKO
DownloadVisualize
BU of 1hko by Molmil
NMR structure of bovine cytochrome b5
Descriptor: CYTOCHROME B5, PROTOPORPHYRIN IX CONTAINING FE
Authors:Muskett, F.W, Whitford, D.
Deposit date:2003-03-10
Release date:2003-03-18
Method:SOLUTION NMR
Cite:The Solution Structure of Bovine Ferricytochrome B5 Determined Using Heteronuclear NMR Methods.
J.Mol.Biol., 258, 1996
2L1M
DownloadVisualize
BU of 2l1m by Molmil
Solution structure of the eag domain of the hERG (Kv11.1) K+ channel
Descriptor: Potassium voltage-gated channel subfamily H member 2
Authors:Muskett, F.W, Mitcheson, J.S.
Deposit date:2010-07-29
Release date:2011-01-19
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Mechanistic insight into human ether-a-go-go-related gene (hERG) K+ channel deactivation gating from the solution structure of the EAG domain.
J.Biol.Chem., 286, 2011
2G0K
DownloadVisualize
BU of 2g0k by Molmil
Solution Structure of Neocarzinostatin Apo-Protein
Descriptor: Neocarzinostatin
Authors:Muskett, F.W, Stoneman, R.G, Caddick, S, Woolfson, D.N.
Deposit date:2006-02-13
Release date:2006-03-28
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Synthetic Ligands for Apo-Neocarzinostatin
J.Am.Chem.Soc., 128, 2006
2G0L
DownloadVisualize
BU of 2g0l by Molmil
Solution Structure of Neocarzinostatin Apo-Protein with bound Flavone
Descriptor: 2-PHENYL-4H-CHROMEN-4-ONE, NEOCARZINOSTATIN
Authors:Muskett, F.W, Stoneman, R.G, Caddick, S, Woolfson, D.N.
Deposit date:2006-02-13
Release date:2006-03-28
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Synthetic Ligands for Apo-Neocarzinostatin
J.Am.Chem.Soc., 128, 2006
5O57
DownloadVisualize
BU of 5o57 by Molmil
Solution Structure of the N-terminal Region of Dkk4
Descriptor: Dickkopf-related protein 4
Authors:Waters, L.C, Patel, S, Barkell, A.M, Muskett, F.W, Robinson, M.K, Holdsworth, G, Carr, M.D.
Deposit date:2017-06-01
Release date:2018-06-13
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural and functional analysis of Dickkopf 4 (Dkk4): New insights into Dkk evolution and regulation of Wnt signaling by Dkk and Kremen proteins.
J. Biol. Chem., 293, 2018
4F8A
DownloadVisualize
BU of 4f8a by Molmil
Cyclic nucleotide binding-homology domain from mouse EAG1 potassium channel
Descriptor: Potassium voltage-gated channel subfamily H member 1
Authors:Marques-Carvalho, M.J, Sahoo, N, Muskett, F.W, Vieira-Pires, R.S, Gabant, G, Cadene, M, Schonherr, R, Morais-Cabral, J.H.
Deposit date:2012-05-17
Release date:2012-07-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural, Biochemical, and Functional Characterization of the Cyclic Nucleotide Binding Homology Domain from the Mouse EAG1 Potassium Channel.
J.Mol.Biol., 423, 2012
1RGW
DownloadVisualize
BU of 1rgw by Molmil
Solution Structure of ZASP's PDZ domain
Descriptor: ZASP protein
Authors:Au, Y, Atkinson, R.A, Pallavicini, A, Joseph, C, Martin, S.R, Muskett, F.W, Guerrini, R, Faulkner, G, Pastore, A.
Deposit date:2003-11-13
Release date:2004-04-13
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:Solution Structure of ZASP PDZ Domain; Implications for Sarcomere Ultrastructure and Enigma Family Redundancy.
Structure, 12, 2004
1WA8
DownloadVisualize
BU of 1wa8 by Molmil
Solution Structure of the CFP-10.ESAT-6 Complex. Major Virulence Determinants of Pathogenic Mycobacteria
Descriptor: 6 KDA EARLY SECRETORY ANTIGENIC TARGET (ESAT-6), ESAT-6 LIKE PROTEIN ESXB
Authors:Renshaw, P.S, Lightbody, K.L, Veverka, V, Muskett, F.W, Kelly, G, Frenkiel, T.A, Gordon, S.V, Hewinson, R.G, Burke, B, Norman, J, Williamson, R.A, Carr, M.D, TB Structural Genomics Consortium (TBSGC)
Deposit date:2004-10-25
Release date:2005-06-27
Last modified:2019-08-21
Method:SOLUTION NMR
Cite:Structure and Function of the Complex Formed by the Tuberculosis Virulence Factors Cfp-10 and Esat-6
Embo J., 24, 2005
2BQZ
DownloadVisualize
BU of 2bqz by Molmil
Crystal structure of a ternary complex of the human histone methyltransferase Pr-SET7 (also known as SET8)
Descriptor: HISTONE H4, S-ADENOSYL-L-HOMOCYSTEINE, SET8 PROTEIN
Authors:Xiao, B, Jing, C, Kelly, G, Walker, P.A, Muskett, F.W, Frenkiel, T.A, Martin, S.R, Sarma, K, Reinberg, D, Gamblin, S.J, Wilson, J.R.
Deposit date:2005-04-28
Release date:2005-06-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Specificity and Mechanism of the Histone Methyltransferase Pr-Set7
Genes Dev., 19, 2005
1H8B
DownloadVisualize
BU of 1h8b by Molmil
EF-hands 3,4 from alpha-actinin / Z-repeat 7 from titin
Descriptor: ALPHA-ACTININ 2, SKELETAL MUSCLE ISOFORM, TITIN
Authors:Atkinson, R.A, Joseph, C, Kelly, G, Muskett, F.W, Frenkiel, T.A, Nietlispach, D, Pastore, A.
Deposit date:2001-02-01
Release date:2001-08-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Ca2+-Independent Binding of an EF-Hand Domain to a Novel Motif in the Alpha-Actinin-Titin Complex
Nat.Struct.Biol., 8, 2001
1J5H
DownloadVisualize
BU of 1j5h by Molmil
Solution Structure of Apo-Neocarzinostatin
Descriptor: Apo-Neocarzinostatin
Authors:Urbaniak, M.D, Muskett, F.W, Finucane, M.D, Caddick, S, Woolfson, D.N.
Deposit date:2002-05-02
Release date:2002-09-11
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution Structure of a Novel Chromoprotein Derived from Apo-Neocarzinostatin and a Synthetic Chromophore
Biochemistry, 41, 2002
1J5I
DownloadVisualize
BU of 1j5i by Molmil
Solution Structure of a Novel Chromoprotein Derived from Apo-Neocarzinostatin and a Synthetic Chromophore
Descriptor: 2-HYDROXY-7-METHOXY-5-METHYL-NAPHTHALENE-1-CARBOXYLIC ACID MESO-2,5-DIHYDROXY-CYCLOPENT-3-ENYL ESTER, PROTEIN (Apo-Neocarzinostatin)
Authors:Urbaniak, M.D, Muskett, F.W, Finucane, M.D, Caddick, S, Woolfson, D.N.
Deposit date:2002-05-02
Release date:2002-09-11
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution Structure of a Novel Chromoprotein Derived from Apo-Neocarzinostatin and a Synthetic Chromophore
Biochemistry, 41, 2002
2HM8
DownloadVisualize
BU of 2hm8 by Molmil
Solution Structure of the C-terminal MA-3 domain of Pdcd4
Descriptor: Pdcd4 C-terminal MA-3 domain
Authors:Waters, L.C, Veverka, V, Bohm, M, Muskett, F.W, Choong, P.T, Klempnauer, K.H, Carr, M.D.
Deposit date:2006-07-11
Release date:2007-02-20
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Structure of the C-terminal MA-3 domain of the tumour suppressor protein Pdcd4 and characterization of its interaction with eIF4A
Oncogene, 26, 2007
2KH2
DownloadVisualize
BU of 2kh2 by Molmil
Solution structure of a scFv-IL-1B complex
Descriptor: Interleukin-1 beta, scFv
Authors:Wilkinson, I.C, Hall, C.J, Veverka, V, Muskett, F.W, Stephens, P.E, Taylor, R.J, Henry, A.J, Carr, M.D.
Deposit date:2009-03-23
Release date:2009-09-08
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:High resolution NMR-based model for the structure of a scFv-IL-1beta complex: potential for NMR as a key tool in therapeutic antibody design and development.
J.Biol.Chem., 284, 2009
2K8P
DownloadVisualize
BU of 2k8p by Molmil
Characterisation of the structural features and interactions of sclerostin: molecular insight into a key regulator of Wnt-mediated bone formation
Descriptor: Sclerostin
Authors:Veverka, V, Henry, A.J, Slocombe, P.M, Ventom, A, Mulloy, B, Muskett, F.W, Muzylak, M, Greenslade, K, Moore, A, Zhang, L, Gong, J, Qian, X, Paszty, C, Taylor, R.J, Robinson, M.K, Carr, M.D.
Deposit date:2008-09-18
Release date:2009-02-17
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Characterization of the Structural Features and Interactions of Sclerostin: Molecular insight into a key regulator of Wnt-mediated bone formation
J.Biol.Chem., 284, 2009
2L3Y
DownloadVisualize
BU of 2l3y by Molmil
Solution structure of mouse IL-6
Descriptor: Interleukin-6
Authors:Veverka, V, Redpath, N.T, Carrington, B, Muskett, F.W, Taylor, R.J, Henry, A.J, Carr, M.D.
Deposit date:2010-09-25
Release date:2011-09-28
Last modified:2013-01-02
Method:SOLUTION NMR
Cite:Conservation of functional sites on interleukin-6 and implications for evolution of signaling complex assembly and therapeutic intervention.
J.Biol.Chem., 287, 2012
2KZT
DownloadVisualize
BU of 2kzt by Molmil
Structure of the Tandem MA-3 Region of Pdcd4
Descriptor: Programmed cell death protein 4
Authors:Waters, L.C, Strong, S.L, Oka, O, Muskett, F.W, Veverka, V, Banerjee, S, Schmedt, T, Henry, A.J, Klempnauer, K.H, Carr, M.D.
Deposit date:2010-06-24
Release date:2011-03-16
Last modified:2011-11-23
Method:SOLUTION NMR
Cite:Structure of the tandem MA-3 region of Pdcd4 protein and characterization of its interactions with eIF4A and eIF4G: molecular mechanisms of a tumor suppressor
J.Biol.Chem., 286, 2011
2M4V
DownloadVisualize
BU of 2m4v by Molmil
Mycobacterium tuberculosis RNA polymerase binding protein A (RbpA) and its interactions with sigma factors
Descriptor: Putative uncharacterized protein
Authors:Bortoluzzi, A, Muskett, F.W, Waters, L.C, Addis, P.W, Rieck, B, Munder, T, Schleier, S, Forti, F, Ghisotti, D, Carr, M.D, O'Hare, H.M.
Deposit date:2013-02-11
Release date:2013-04-17
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Mycobacterium tuberculosis RNA polymerase-binding protein A (RbpA) and its interactions with sigma factors.
J.Biol.Chem., 288, 2013
2M2D
DownloadVisualize
BU of 2m2d by Molmil
Human programmed cell death 1 receptor
Descriptor: Programmed cell death protein 1
Authors:Veverka, V, Cheng, X, Waters, L.C, Muskett, F.W, Morgan, S, Lesley, A, Griffiths, M, Stubberfield, C, Griffin, R, Henry, A.J, Robinson, M.K, Jansson, A, Ladbury, J.E, Ikemizu, S, Davis, S.J, Carr, M.D.
Deposit date:2012-12-18
Release date:2013-02-27
Last modified:2013-05-15
Method:SOLUTION NMR
Cite:Structure and interactions of the human programmed cell death 1 receptor.
J.Biol.Chem., 288, 2013
2MWI
DownloadVisualize
BU of 2mwi by Molmil
The structure of the carboxy-terminal domain of DNTTIP1
Descriptor: Deoxynucleotidyltransferase terminal-interacting protein 1
Authors:Schwabe, J.W.R, Muskett, F.W, Itoh, T.
Deposit date:2014-11-11
Release date:2015-02-18
Last modified:2015-03-18
Method:SOLUTION NMR
Cite:Structural and functional characterization of a cell cycle associated HDAC1/2 complex reveals the structural basis for complex assembly and nucleosome targeting.
Nucleic Acids Res., 43, 2015
2NPU
DownloadVisualize
BU of 2npu by Molmil
The solution structure of the rapamycin-binding domain of mTOR (FRB)
Descriptor: FKBP12-rapamycin complex-associated protein
Authors:Veverka, V, Crabbe, T, Bird, I, Lennie, G, Muskett, F.W, Taylor, R.J, Carr, M.D.
Deposit date:2006-10-30
Release date:2007-09-18
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural characterization of the interaction of mTOR with phosphatidic acid and a novel class of inhibitor: compelling evidence for a central role of the FRB domain in small molecule-mediated regulation of mTOR.
Oncogene, 27, 2008
8P0D
DownloadVisualize
BU of 8p0d by Molmil
Human 14-3-3 sigma in complex with human MDM2 peptide
Descriptor: 14-3-3 protein sigma, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Roversi, P, Ward, J, Doveston, R, Kwon, H, Romartinez Alonso, B.
Deposit date:2023-05-10
Release date:2024-02-21
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:Characterizing the protein-protein interaction between MDM2 and 14-3-3 sigma ; proof of concept for small molecule stabilization.
J.Biol.Chem., 300, 2024
5FB8
DownloadVisualize
BU of 5fb8 by Molmil
Structure of Interleukin-16 bound to the 14.1 antibody
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Anti-IL-16 antibody 14.1 Fab domain Heavy Chain, ...
Authors:Hall, G, Cowan, R, Bayliss, R, Carr, M.
Deposit date:2015-12-14
Release date:2016-06-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structure of a Potential Therapeutic Antibody Bound to Interleukin-16 (IL-16): MECHANISTIC INSIGHTS AND NEW THERAPEUTIC OPPORTUNITIES.
J.Biol.Chem., 291, 2016

 

12>

217157

PDB entries from 2024-03-13

PDB statisticsPDBj update infoContact PDBjnumon