Author results

1HKO
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NMR STRUCTURE OF BOVINE CYTOCHROME B5
分子名称:CYTOCHROME B5, PROTOPORPHYRIN IX CONTAINING FE
著者Muskett, F.W., Whitford, D.
登録日2003-03-10
公開日2003-03-18
実験手法SOLUTION NMR
主引用文献The Solution Structure of Bovine Ferricytochrome B5 Determined Using Heteronuclear NMR Methods.
J.Mol.Biol., 258, 1996
1PE3
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SOLUTION STRUCTURE OF THE DISULPHIDE-LINKED DIMER OF HUMAN INTESTINAL TREFOIL FACTOR (TFF3)
分子名称:Trefoil factor 3
著者Muskett, F.W., May, F.E., Westley, B.R., Feeney, J.
登録日2003-05-21
公開日2004-03-09
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure of the disulfide-linked dimer of human intestinal trefoil factor (TFF3): the intermolecular orientation and interactions are markedly different from those of other dimeric trefoil proteins.
Biochemistry, 42, 2003
2L1M
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SOLUTION STRUCTURE OF THE EAG DOMAIN OF THE HERG (KV11.1) K+ CHANNEL
分子名称:Potassium voltage-gated channel subfamily H member 2
著者Muskett, F.W., Mitcheson, J.S.
登録日2010-07-29
公開日2011-01-19
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Mechanistic insight into human ether-a-go-go-related gene (hERG) K+ channel deactivation gating from the solution structure of the EAG domain.
J.Biol.Chem., 286, 2011
2TMP
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N-TERMINAL DOMAIN OF TISSUE INHIBITOR OF METALLOPROTEINASE-2 (N-TIMP-2), NMR, 49 STRUCTURES
分子名称:TISSUE INHIBITOR OF METALLOPROTEINASES-2
著者Muskett, F.W., Frenkiel, T.A., Feeney, J., Freedman, R.B., Carr, M.D., Williamson, R.A.
登録日1998-05-26
公開日1998-12-09
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献High resolution structure of the N-terminal domain of tissue inhibitor of metalloproteinases-2 and characterization of its interaction site with matrix metalloproteinase-3.
J.Biol.Chem., 273, 1998
2G0K
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SOLUTION STRUCTURE OF NEOCARZINOSTATIN APO-PROTEIN
分子名称:Neocarzinostatin
著者Muskett, F.W., Stoneman, R.G., Caddick, S., Woolfson, D.N.
登録日2006-02-13
公開日2006-03-28
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Synthetic Ligands for Apo-Neocarzinostatin
J.Am.Chem.Soc., 128, 2006
2G0L
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SOLUTION STRUCTURE OF NEOCARZINOSTATIN APO-PROTEIN WITH BOUND FLAVONE
分子名称:NEOCARZINOSTATIN, 2-PHENYL-4H-CHROMEN-4-ONE
著者Muskett, F.W., Stoneman, R.G., Caddick, S., Woolfson, D.N.
登録日2006-02-13
公開日2006-03-28
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Synthetic Ligands for Apo-Neocarzinostatin
J.Am.Chem.Soc., 128, 2006
1H8B
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EF-HANDS 3,4 FROM ALPHA-ACTININ / Z-REPEAT 7 FROM TITIN
分子名称:ALPHA-ACTININ 2, SKELETAL MUSCLE ISOFORM, TITIN
著者Atkinson, R.A., Joseph, C., Kelly, G., Muskett, F.W., Frenkiel, T.A., Nietlispach, D., Pastore, A.
登録日2001-02-01
公開日2001-08-30
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Ca2+-Independent Binding of an EF-Hand Domain to a Novel Motif in the Alpha-Actinin-Titin Complex
Nat.Struct.Biol., 8, 2001
1J5H
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SOLUTION STRUCTURE OF APO-NEOCARZINOSTATIN
分子名称:Apo-Neocarzinostatin
著者Urbaniak, M.D., Muskett, F.W., Finucane, M.D., Caddick, S., Woolfson, D.N.
登録日2002-05-02
公開日2002-09-11
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution Structure of a Novel Chromoprotein Derived from Apo-Neocarzinostatin and a Synthetic Chromophore
Biochemistry, 41, 2002
1J5I
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SOLUTION STRUCTURE OF A NOVEL CHROMOPROTEIN DERIVED FROM APO-NEOCARZINOSTATIN AND A SYNTHETIC CHROMOPHORE
分子名称:PROTEIN (Apo-Neocarzinostatin), 2-HYDROXY-7-METHOXY-5-METHYL-NAPHTHALENE-1-CARBOXYLIC ACID MESO-2,5-DIHYDROXY-CYCLOPENT-3-ENYL ESTER
著者Urbaniak, M.D., Muskett, F.W., Finucane, M.D., Caddick, S., Woolfson, D.N.
登録日2002-05-02
公開日2002-09-11
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution Structure of a Novel Chromoprotein Derived from Apo-Neocarzinostatin and a Synthetic Chromophore
Biochemistry, 41, 2002
1RGW
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SOLUTION STRUCTURE OF ZASP'S PDZ DOMAIN
分子名称:ZASP protein
著者Au, Y., Atkinson, R.A., Pallavicini, A., Joseph, C., Martin, S.R., Muskett, F.W., Guerrini, R., Faulkner, G., Pastore, A.
登録日2003-11-13
公開日2004-04-13
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution Structure of ZASP PDZ Domain; Implications for Sarcomere Ultrastructure and Enigma Family Redundancy.
Structure, 12, 2004
1WA8
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SOLUTION STRUCTURE OF THE CFP-10.ESAT-6 COMPLEX. MAJOR VIRULENCE DETERMINANTS OF PATHOGENIC MYCOBACTERIA
分子名称:ESAT-6 LIKE PROTEIN ESXB, 6 KDA EARLY SECRETORY ANTIGENIC TARGET (ESAT-6)
著者Renshaw, P.S., Lightbody, K.L., Veverka, V., Muskett, F.W., Kelly, G., Frenkiel, T.A., Gordon, S.V., Hewinson, R.G., Burke, B., Norman, J., Williamson, R.A., Carr, M.D., TB Structural Genomics Consortium (TBSGC)
登録日2004-10-25
公開日2005-06-27
最終更新日2019-08-21
実験手法SOLUTION NMR
主引用文献Structure and Function of the Complex Formed by the Tuberculosis Virulence Factors Cfp-10 and Esat-6
Embo J., 24, 2005
2BQZ
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CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF THE HUMAN HISTONE METHYLTRANSFERASE PR-SET7 (ALSO KNOWN AS SET8)
分子名称:SET8 PROTEIN, HISTONE H4, S-ADENOSYL-L-HOMOCYSTEINE
著者Xiao, B., Jing, C., Kelly, G., Walker, P.A., Muskett, F.W., Frenkiel, T.A., Martin, S.R., Sarma, K., Reinberg, D., Gamblin, S.J., Wilson, J.R.
登録日2005-04-28
公開日2005-06-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Specificity and Mechanism of the Histone Methyltransferase Pr-Set7
Genes Dev., 19, 2005
2HM8
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SOLUTION STRUCTURE OF THE C-TERMINAL MA-3 DOMAIN OF PDCD4
分子名称:Pdcd4 C-terminal MA-3 domain
著者Waters, L.C., Veverka, V., Bohm, M., Muskett, F.W., Choong, P.T., Klempnauer, K.H., Carr, M.D.
登録日2006-07-11
公開日2007-02-20
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structure of the C-terminal MA-3 domain of the tumour suppressor protein Pdcd4 and characterization of its interaction with eIF4A
Oncogene, 26, 2007
2K8P
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CHARACTERISATION OF THE STRUCTURAL FEATURES AND INTERACTIONS OF SCLEROSTIN: MOLECULAR INSIGHT INTO A KEY REGULATOR OF WNT-MEDIATED BONE FORMATION
分子名称:Sclerostin
著者Veverka, V., Henry, A.J., Slocombe, P.M., Ventom, A., Mulloy, B., Muskett, F.W., Muzylak, M., Greenslade, K., Moore, A., Zhang, L., Gong, J., Qian, X., Paszty, C., Taylor, R.J., Robinson, M.K., Carr, M.D.
登録日2008-09-18
公開日2009-02-17
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Characterization of the Structural Features and Interactions of Sclerostin: Molecular insight into a key regulator of Wnt-mediated bone formation
J.Biol.Chem., 284, 2009
2KH2
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SOLUTION STRUCTURE OF A SCFV-IL-1B COMPLEX
分子名称:Interleukin-1 beta, scFv
著者Wilkinson, I.C., Hall, C.J., Veverka, V., Muskett, F.W., Stephens, P.E., Taylor, R.J., Henry, A.J., Carr, M.D.
登録日2009-03-23
公開日2009-09-08
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献High resolution NMR-based model for the structure of a scFv-IL-1beta complex: potential for NMR as a key tool in therapeutic antibody design and development.
J.Biol.Chem., 284, 2009
2KZT
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STRUCTURE OF THE TANDEM MA-3 REGION OF PDCD4
分子名称:Programmed cell death protein 4
著者Waters, L.C., Strong, S.L., Oka, O., Muskett, F.W., Veverka, V., Banerjee, S., Schmedt, T., Henry, A.J., Klempnauer, K.H., Carr, M.D.
登録日2010-06-24
公開日2011-03-16
最終更新日2011-11-23
実験手法SOLUTION NMR
主引用文献Structure of the tandem MA-3 region of Pdcd4 protein and characterization of its interactions with eIF4A and eIF4G: molecular mechanisms of a tumor suppressor
J.Biol.Chem., 286, 2011
2L3Y
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SOLUTION STRUCTURE OF MOUSE IL-6
分子名称:Interleukin-6
著者Veverka, V., Redpath, N.T., Carrington, B., Muskett, F.W., Taylor, R.J., Henry, A.J., Carr, M.D.
登録日2010-09-25
公開日2011-09-28
最終更新日2013-01-02
実験手法SOLUTION NMR
主引用文献Conservation of functional sites on interleukin-6 and implications for evolution of signaling complex assembly and therapeutic intervention.
J.Biol.Chem., 287, 2012
2M2D
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HUMAN PROGRAMMED CELL DEATH 1 RECEPTOR
分子名称:Programmed cell death protein 1
著者Veverka, V., Cheng, X., Waters, L.C., Muskett, F.W., Morgan, S., Lesley, A., Griffiths, M., Stubberfield, C., Griffin, R., Henry, A.J., Robinson, M.K., Jansson, A., Ladbury, J.E., Ikemizu, S., Davis, S.J., Carr, M.D.
登録日2012-12-18
公開日2013-02-27
最終更新日2013-05-15
実験手法SOLUTION NMR
主引用文献Structure and interactions of the human programmed cell death 1 receptor.
J.Biol.Chem., 288, 2013
2M4V
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MYCOBACTERIUM TUBERCULOSIS RNA POLYMERASE BINDING PROTEIN A (RBPA) AND ITS INTERACTIONS WITH SIGMA FACTORS
分子名称:Putative uncharacterized protein
著者Bortoluzzi, A., Muskett, F.W., Waters, L.C., Addis, P.W., Rieck, B., Munder, T., Schleier, S., Forti, F., Ghisotti, D., Carr, M.D., O'Hare, H.M.
登録日2013-02-11
公開日2013-04-17
最終更新日2013-08-07
実験手法SOLUTION NMR
主引用文献Mycobacterium tuberculosis RNA polymerase-binding protein A (RbpA) and its interactions with sigma factors.
J.Biol.Chem., 288, 2013
2MWI
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THE STRUCTURE OF THE CARBOXY-TERMINAL DOMAIN OF DNTTIP1
分子名称:Deoxynucleotidyltransferase terminal-interacting protein 1
著者Schwabe, J.W.R., Muskett, F.W., Itoh, T.
登録日2014-11-11
公開日2015-02-18
最終更新日2015-03-18
実験手法SOLUTION NMR
主引用文献Structural and functional characterization of a cell cycle associated HDAC1/2 complex reveals the structural basis for complex assembly and nucleosome targeting.
Nucleic Acids Res., 43, 2015
2NPU
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THE SOLUTION STRUCTURE OF THE RAPAMYCIN-BINDING DOMAIN OF MTOR (FRB)
分子名称:FKBP12-rapamycin complex-associated protein
著者Veverka, V., Crabbe, T., Bird, I., Lennie, G., Muskett, F.W., Taylor, R.J., Carr, M.D.
登録日2006-10-30
公開日2007-09-18
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structural characterization of the interaction of mTOR with phosphatidic acid and a novel class of inhibitor: compelling evidence for a central role of the FRB domain in small molecule-mediated regulation of mTOR.
Oncogene, 27, 2008
4F8A
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CYCLIC NUCLEOTIDE BINDING-HOMOLOGY DOMAIN FROM MOUSE EAG1 POTASSIUM CHANNEL
分子名称:Potassium voltage-gated channel subfamily H member 1
著者Marques-Carvalho, M.J., Sahoo, N., Muskett, F.W., Vieira-Pires, R.S., Gabant, G., Cadene, M., Schonherr, R., Morais-Cabral, J.H.
登録日2012-05-17
公開日2012-07-11
最終更新日2012-10-17
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural, Biochemical, and Functional Characterization of the Cyclic Nucleotide Binding Homology Domain from the Mouse EAG1 Potassium Channel.
J.Mol.Biol., 423, 2012
5O57
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SOLUTION STRUCTURE OF THE N-TERMINAL REGION OF DKK4
分子名称:Dickkopf-related protein 4
著者Waters, L.C., Patel, S., Barkell, A.M., Muskett, F.W., Robinson, M.K., Holdsworth, G., Carr, M.D.
登録日2017-06-01
公開日2018-06-13
最終更新日2019-05-08
実験手法SOLUTION NMR
主引用文献Structural and functional analysis of Dickkopf 4 (Dkk4): New insights into Dkk evolution and regulation of Wnt signaling by Dkk and Kremen proteins.
J. Biol. Chem., 293, 2018
1E9T
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HIGH RESOLUTION SOLUTION STRUCTURE OF HUMAN INTESTINAL TREFOIL FACTOR
分子名称:INTESTINAL TREFOIL FACTOR
著者Lemercinier, X., Muskett, F., Cheeseman, B., McIntosh, P., Carr, M.
登録日2000-10-26
公開日2000-12-08
最終更新日2017-04-19
実験手法SOLUTION NMR
主引用文献High-Resolution Solution Structure of Human Intestinal Trefoil Factor and Functional Insights from Detailed Structural Comparisons with the Other Members of the Trefoil Family of Mammalian Cell Motility Factors
Biochemistry, 40, 2001
2C52
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STRUCTURAL DIVERSITY IN CBP P160 COMPLEXES
分子名称:CREB-BINDING PROTEIN, NUCLEAR RECEPTOR COACTIVATOR 1
著者Waters, L.C., Yue, B., Veverka, V., Renshaw, P.S., Bramham, J., Matsuda, S., Frenkiel, T., Kelly, G., Muskett, F.W., Carr, M.D., Heery, D.M.
登録日2005-10-25
公開日2006-03-15
最終更新日2018-05-02
実験手法SOLUTION NMR
主引用文献Structural diversity in p160/CREB-binding protein coactivator complexes.
J. Biol. Chem., 281, 2006
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