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5FEH
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CRYSTAL STRUCTURE OF PCT64_35B, A BROADLY NEUTRALIZING ANTI-HIV ANTIBODY
Descriptor:PCT64_26 Fab light chain, PCT64_26 Fab heavy chain, SULFATE ION, ...
Authors:Murrell, S., Wilson, I.A.
Deposit date:2015-12-17
Release date:2017-08-16
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:HIV Envelope Glycoform Heterogeneity and Localized Diversity Govern the Initiation and Maturation of a V2 Apex Broadly Neutralizing Antibody Lineage.
Immunity, 47, 2017
4YAQ
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CRYSTAL STRUCTURE OF A COMPUTATIONALLY OPTIMIZED PG9 MUTANT
Descriptor:PG9_N100FY Fab heavy chain, PG9_N100FY Light Chain, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
Authors:Murrell, S., Julien, J.P., Wilson, I.A.
Deposit date:2015-02-17
Release date:2015-06-03
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Redesigned HIV antibodies exhibit enhanced neutralizing potency and breadth.
J.Clin.Invest., 125, 2015
6B3D
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CRYSTAL STRUCTURE OF ANTI-HIV ANTIBODY PGT128 IN COMPLEX WITH A BACTERIALLY DERIVED SYNTHETIC MIMETIC OF MAN9.
Descriptor:PGT128 Fab light chain, PGT128 Fab heavy chain, GLYCEROL, ...
Authors:Murrell, S., Wilson, I.A.
Deposit date:2017-09-21
Release date:2017-12-06
Method:X-RAY DIFFRACTION (2.271 Å)
Cite:Bacterially derived synthetic mimetics of mammalian oligomannose prime antibody responses that neutralize HIV infectivity.
Nat Commun, 8, 2017
6CA6
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CRYSTAL STRUCTURE OF PCT64_35S, A BROADLY NEUTRALIZING ANTI-HIV ANTIBODY.
Descriptor:PCT64_35S light chain, PCT64_35S heavy chain, DI(HYDROXYETHYL)ETHER, ...
Authors:Murrell, S., Wilson, I.A.
Deposit date:2018-01-29
Release date:2018-06-27
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design.
Cell Rep, 23, 2018
6CA7
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CRYSTAL STRUCTURE OF PCT64_13C, A STRAIN SPECIFIC ANTI-HIV ANTIBODY
Descriptor:PCT64_13C light chain, PCT64_13C heavy chain
Authors:Murrell, S., Wilson, I.A.
Deposit date:2018-01-29
Release date:2018-06-27
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (1.643 Å)
Cite:Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design.
Cell Rep, 23, 2018
6CA9
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CRYSTAL STRUCTURE OF FAB PCT64_LMCA (SAR), THE LEAST MUTATED COMMON ANCESTOR OF THE HIV-1 BROADLY NEUTRALIZING ANTIBODY LINEAGE PCT64
Descriptor:PCT64_LMCA Fab light chain, PCT64_LMCA Fab heavy chain, GLYCEROL, ...
Authors:Omorodion, O., Wilson, I.A.
Deposit date:2018-01-29
Release date:2018-06-27
Method:X-RAY DIFFRACTION (2.702 Å)
Cite:Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design.
Cell Rep, 23, 2018
6DCQ
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ECTODOMAIN OF FULL LENGTH, WILD TYPE HIV-1 GLYCOPROTEIN CLONE PC64M18C043 IN COMPLEX WITH PGT151 FAB
Descriptor:Envelope glycoprotein gp160, Immunoglobulin G PGT151 Fab, Heavy chain, ...
Authors:Rantalainen, K.
Deposit date:2018-05-08
Release date:2018-06-27
Last modified:2018-07-04
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design.
Cell Rep, 23, 2018