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3FN1
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BU of 3fn1 by Molmil
E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification.
Descriptor: NEDD8-activating enzyme E1 catalytic subunit, NEDD8-conjugating enzyme UBE2F
Authors:Huang, D.T, Ayrault, O, Hunt, H.W, Taherbhoy, A.M, Duda, D.M, Scott, D.C, Borg, L.A, Neale, G, Murray, P.J, Roussel, M.F, Schulman, B.A.
Deposit date:2008-12-22
Release date:2009-03-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification
Mol.Cell, 33, 2009
8PDA
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BU of 8pda by Molmil
cryo-EM structure of Doa10 with RING domain in MSP1E3D1
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATE, ERAD-associated E3 ubiquitin-protein ligase DOA10
Authors:Botsch, J.J, Braeuning, B, Schulman, B.A.
Deposit date:2023-06-12
Release date:2024-01-17
Method:ELECTRON MICROSCOPY (3.58 Å)
Cite:Doa10/MARCH6 architecture interconnects E3 ligase activity with lipid-binding transmembrane channel to regulate SQLE.
Nat Commun, 15, 2024
8PD0
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BU of 8pd0 by Molmil
cryo-EM structure of Doa10 in MSP1E3D1
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATE, ERAD-associated E3 ubiquitin-protein ligase DOA10
Authors:Botsch, J.J, Braeuning, B, Schulman, B.A.
Deposit date:2023-06-11
Release date:2024-01-17
Method:ELECTRON MICROSCOPY (3.58 Å)
Cite:Doa10/MARCH6 architecture interconnects E3 ligase activity with lipid-binding transmembrane channel to regulate SQLE.
Nat Commun, 15, 2024
8CAF
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BU of 8caf by Molmil
N8C_Fab3b in complex with NEDD8-CUL1(WHB)
Descriptor: Cullin-1, Fab Heavy Chain, Fab Light Chain, ...
Authors:Duda, D.M, Yanishevski, D, Henneberg, L.T, Schulman, B.A.
Deposit date:2023-01-24
Release date:2023-09-13
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Activity-based profiling of cullin-RING E3 networks by conformation-specific probes.
Nat.Chem.Biol., 19, 2023
6SYT
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BU of 6syt by Molmil
Structure of the SMG1-SMG8-SMG9 complex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ...
Authors:Gat, Y, Schuller, J.M, Conti, E.
Deposit date:2019-10-01
Release date:2019-12-11
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (3.45 Å)
Cite:InsP6binding to PIKK kinases revealed by the cryo-EM structure of an SMG1-SMG8-SMG9 complex.
Nat.Struct.Mol.Biol., 26, 2019

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