5TO3
 
 | | Crystal structure of thrombin mutant W215A/E217A fused to EGF456 of thrombomodulin via a 31-residue linker and bound to PPACK | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-4)-alpha-D-mannopyranose-(1-4)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, ... | | Authors: | Barranco-Medina, S, Murphy, M, Pelc, L, Chen, Z, Di Cera, E, Pozzi, N. | | Deposit date: | 2016-10-16 | | Release date: | 2017-03-29 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.34 Å) | | Cite: | Rational Design of Protein C Activators.
Sci Rep, 7, 2017
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2X55
 | | Yersinia Pestis Plasminogen Activator Pla (Native) | | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, COAGULASE/FIBRINOLYSIN, SULFATE ION | | Authors: | Eren, E, Murphy, M, Goguen, J, van den Berg, B. | | Deposit date: | 2010-02-05 | | Release date: | 2010-07-28 | | Last modified: | 2018-01-24 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | An Active Site Water Network in the Plasminogen Activator Pla from Yersinia Pestis
Structure, 18, 2010
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2X56
 | | Yersinia Pestis Plasminogen Activator Pla (Native) | | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, COAGULASE/FIBRINOLYSIN | | Authors: | Eren, E, Murphy, M, Goguen, J, van den Berg, B. | | Deposit date: | 2010-02-05 | | Release date: | 2010-07-28 | | Last modified: | 2018-01-24 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | An Active Site Water Network in the Plasminogen Activator Pla from Yersinia Pestis
Structure, 18, 2010
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2X4M
 | | Yersinia Pestis Plasminogen Activator Pla | | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, COAGULASE/FIBRINOLYSIN, SULFATE ION | | Authors: | Eren, E, Murphy, M, Goguen, J, van den Berg, B. | | Deposit date: | 2010-02-05 | | Release date: | 2010-07-28 | | Last modified: | 2018-01-24 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | An Active Site Water Network in the Plasminogen Activator Pla from Yersinia Pestis
Structure, 18, 2010
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3HJH
 | | A rigid N-terminal clamp restrains the motor domains of the bacterial transcription-repair coupling factor | | Descriptor: | COBALT (II) ION, Transcription-repair-coupling factor | | Authors: | Murphy, M, Gong, P, Ralto, K, Manelyte, L, Savery, N, Theis, K. | | Deposit date: | 2009-05-21 | | Release date: | 2009-10-20 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | An N-terminal clamp restrains the motor domains of the bacterial transcription-repair coupling factor Mfd.
Nucleic Acids Res., 37, 2009
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7U2T
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7U2Q
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7UNB
 | | Crystal structure of malaria transmission-blocking antigen Pfs48/45-6C variant in complex with human antibodies RUPA-117 and RUPA-47 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Gametocyte surface protein P45/48, RUPA-117 Fab heavy chain, ... | | Authors: | Hailemariam, S, McLeod, B, Julien, J.-P. | | Deposit date: | 2022-04-10 | | Release date: | 2022-08-10 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.18 Å) | | Cite: | Vaccination with a structure-based stabilized version of malarial antigen Pfs48/45 elicits ultra-potent transmission-blocking antibody responses.
Immunity, 55, 2022
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8UR7
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8UR5
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8DTT
 | | Crystal structure of SARS-CoV-2 spike stem helix peptide in complex with neutralizing antibody COV93-03 | | Descriptor: | COV93-03 heavy chain, COV93-03 light chain, Spike protein S2' stem helix peptide | | Authors: | Lee, C.C.D, Lin, T.H, Wilson, I.A. | | Deposit date: | 2022-07-26 | | Release date: | 2022-11-23 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Rare, convergent antibodies targeting the stem helix broadly neutralize diverse betacoronaviruses.
Cell Host Microbe, 31, 2023
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8DTR
 | | Crystal structure of SARS-CoV-2 spike stem helix peptide in complex with neutralizing antibody COV30-14 | | Descriptor: | COV30-14 heavy chain, COV30-14 light chain, Spike protein S2' stem helix peptide | | Authors: | Lee, C.C.D, Lin, T.H, Wilson, I.A. | | Deposit date: | 2022-07-26 | | Release date: | 2022-11-23 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Rare, convergent antibodies targeting the stem helix broadly neutralize diverse betacoronaviruses.
Cell Host Microbe, 31, 2023
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8DTX
 | | Crystal structure of SARS-CoV-2 spike stem helix peptide in complex with neutralizing antibody COV89-22 | | Descriptor: | COV89-22 heavy chain, COV89-22 light chain, Spike protein S2' stem helix peptide | | Authors: | Lin, T.H, Lee, C.C.D, Wilson, I.A. | | Deposit date: | 2022-07-26 | | Release date: | 2022-11-23 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Rare, convergent antibodies targeting the stem helix broadly neutralize diverse betacoronaviruses.
Cell Host Microbe, 31, 2023
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8FBI
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8FBJ
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8FBN
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8FBO
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8FBK
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7Y3I
 | | Structure of DNA bound SALL4 | | Descriptor: | DNA (12-mer), Sal-like protein 4, ZINC ION | | Authors: | Ru, W, Xu, C. | | Deposit date: | 2022-06-10 | | Release date: | 2022-10-26 | | Last modified: | 2022-11-30 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Structural studies of SALL family protein zinc finger cluster domains in complex with DNA reveal preferential binding to an AATA tetranucleotide motif.
J.Biol.Chem., 298, 2022
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7Y3L
 | | Structure of SALL3 ZFC4 bound with 12 bp AT-rich dsDNA | | Descriptor: | DNA (12-mer), Sal-like protein 3, ZINC ION | | Authors: | Ru, W, Xu, C. | | Deposit date: | 2022-06-11 | | Release date: | 2022-10-26 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural studies of SALL family protein zinc finger cluster domains in complex with DNA reveal preferential binding to an AATA tetranucleotide motif.
J.Biol.Chem., 298, 2022
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7Y3K
 | | Structure of SALL4 ZFC4 bound with 16 bp AT-rich dsDNA | | Descriptor: | DNA (16-mer), Sal-like protein 4, ZINC ION | | Authors: | Ru, W, Xu, C. | | Deposit date: | 2022-06-11 | | Release date: | 2022-10-26 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.501 Å) | | Cite: | Structural studies of SALL family protein zinc finger cluster domains in complex with DNA reveal preferential binding to an AATA tetranucleotide motif.
J.Biol.Chem., 298, 2022
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7Y3M
 | | Structure of SALL4 ZFC1 bound with 16 bp AT-rich dsDNA | | Descriptor: | DNA (16-mer), Sal-like protein 4, ZINC ION | | Authors: | Ru, W, Xu, C. | | Deposit date: | 2022-06-11 | | Release date: | 2022-10-26 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.723 Å) | | Cite: | Structural studies of SALL family protein zinc finger cluster domains in complex with DNA reveal preferential binding to an AATA tetranucleotide motif.
J.Biol.Chem., 298, 2022
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7KNA
 | | Localized reconstruction of the H1 A/Michigan/45/2015 ectodomain displayed at the surface of I53_dn5 nanoparticle | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin,I53_dn5 | | Authors: | Acton, O.J, Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | | Deposit date: | 2020-11-04 | | Release date: | 2021-03-31 | | Last modified: | 2021-05-05 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Quadrivalent influenza nanoparticle vaccines induce broad protection.
Nature, 592, 2021
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6O9B
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6O9C
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