1A21
| TISSUE FACTOR (TF) FROM RABBIT | Descriptor: | TISSUE FACTOR | Authors: | Muller, Y.A, De Vos, A.M. | Deposit date: | 1998-01-14 | Release date: | 1998-05-27 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Hinge bending within the cytokine receptor superfamily revealed by the 2.4 A crystal structure of the extracellular domain of rabbit tissue factor. Protein Sci., 7, 1998
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1BJ1
| VASCULAR ENDOTHELIAL GROWTH FACTOR IN COMPLEX WITH A NEUTRALIZING ANTIBODY | Descriptor: | Fab fragment, heavy chain, light chain, ... | Authors: | Muller, Y.A, Christinger, H.W, De Vos, A.M. | Deposit date: | 1998-06-30 | Release date: | 1999-01-13 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | VEGF and the Fab fragment of a humanized neutralizing antibody: crystal structure of the complex at 2.4 A resolution and mutational analysis of the interface. Structure, 6, 1998
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1POW
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1POX
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2VPF
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2HFT
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1VPF
| STRUCTURE OF HUMAN VASCULAR ENDOTHELIAL GROWTH FACTOR | Descriptor: | VASCULAR ENDOTHELIAL GROWTH FACTOR | Authors: | Muller, Y.A, De Vos, A.M. | Deposit date: | 1997-04-08 | Release date: | 1998-04-08 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Vascular endothelial growth factor: crystal structure and functional mapping of the kinase domain receptor binding site. Proc.Natl.Acad.Sci.USA, 94, 1997
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1MJV
| DISULFIDE DEFICIENT MUTANT OF VASCULAR ENDOTHELIAL GROWTH FACTOR A (C51A and C60A) | Descriptor: | Vascular Endothelial Growth Factor A | Authors: | Muller, Y.A, Heiring, C, Misselwitz, R, Welfle, K, Welfle, H. | Deposit date: | 2002-08-28 | Release date: | 2002-12-11 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The cystine knot promotes folding and not thermodynamic stability in vascular endothelial growth factor J.Biol.Chem., 277, 2002
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1MKK
| Disulfide deficient mutant of vascular endothelial growth factor A (C61A and C104A) | Descriptor: | Vascular Endothelial Growth Factor A | Authors: | Muller, Y.A, Heiring, C, Misselwitz, R, Welfle, K, Welfle, H. | Deposit date: | 2002-08-29 | Release date: | 2002-12-11 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (1.32 Å) | Cite: | The cystine knot promotes folding and not thermodynamic stability in vascular endothelial growth factor J.Biol.Chem., 277, 2002
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1MKG
| DISULFIDE DEFICIENT MUTANT OF VASCULAR ENDOTHELIAL GROWTH FACTOR A (C57A and C102A) | Descriptor: | Vascular Endothelial Growth Factor A | Authors: | Muller, Y.A, Heiring, C, Misselwitz, R, Welfle, K, Welfle, H. | Deposit date: | 2002-08-29 | Release date: | 2002-12-11 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The cystine knot promotes folding and not thermodynamic stability in vascular endothelial growth factor J.Biol.Chem., 277, 2002
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6T3X
| Crystal structure of the truncated human cytomegalovirus pUL50-pUL53 complex | Descriptor: | Nuclear egress protein 2,Nuclear egress protein 1 | Authors: | Muller, Y.A. | Deposit date: | 2019-10-11 | Release date: | 2020-02-12 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | High-resolution crystal structures of two prototypical beta- and gamma-herpesviral nuclear egress complexes unravel the determinants of subfamily specificity. J.Biol.Chem., 295, 2020
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6T3Z
| Crystal structure of the truncated EBV BFRF1-BFLF2 nuclear egress complex | Descriptor: | MALONATE ION, Nuclear egress protein 2,Nuclear egress protein 1 | Authors: | Muller, Y.A. | Deposit date: | 2019-10-11 | Release date: | 2020-02-12 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.55862784 Å) | Cite: | High-resolution crystal structures of two prototypical beta- and gamma-herpesviral nuclear egress complexes unravel the determinants of subfamily specificity. J.Biol.Chem., 295, 2020
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6EL3
| Structure of Progesterone 5beta-Reductase from Arabidopsis thaliana in complex with NADP | Descriptor: | 3-oxo-Delta(4,5)-steroid 5-beta-reductase, CHLORIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Muller, Y.A, Schmidt, K, Egerer-Sieber, C. | Deposit date: | 2017-09-27 | Release date: | 2018-09-05 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.899 Å) | Cite: | PRISEs (progesterone 5 beta-reductase and/or iridoid synthase-like 1,4-enone reductases): Catalytic and substrate promiscuity allows for realization of multiple pathways in plant metabolism. Phytochemistry, 156, 2018
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1F5F
| CRYSTAL STRUCTURE OF THE N-TERMINAL G-DOMAIN OF SHBG IN COMPLEX WITH ZINC | Descriptor: | 5-ALPHA-DIHYDROTESTOSTERONE, CALCIUM ION, ISOPROPYL ALCOHOL, ... | Authors: | Avvakumov, V.A, Muller, Y.A, Hammond, G.L. | Deposit date: | 2000-06-14 | Release date: | 2000-09-06 | Last modified: | 2018-04-04 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Steroid-binding specificity of human sex hormone-binding globulin is influenced by occupancy of a zinc-binding site. J.Biol.Chem., 275, 2000
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4WID
| Crystal structure of the immediate-early 1 protein (IE1) at 2.31 angstrom (tetragonal form after crystal dehydration) | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, RhUL123 | Authors: | Klingl, S, Scherer, M, Sevvana, M, Muller, Y.A, Stamminger, T. | Deposit date: | 2014-09-25 | Release date: | 2014-10-29 | Last modified: | 2017-09-06 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Crystal Structure of Cytomegalovirus IE1 Protein Reveals Targeting of TRIM Family Member PML via Coiled-Coil Interactions. Plos Pathog., 10, 2014
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1D2S
| CRYSTAL STRUCTURE OF THE N-TERMINAL LAMININ G-LIKE DOMAIN OF SHBG IN COMPLEX WITH DIHYDROTESTOSTERONE | Descriptor: | 5-ALPHA-DIHYDROTESTOSTERONE, CALCIUM ION, SEX HORMONE-BINDING GLOBULIN | Authors: | Grishkovskaya, I, Avvakumov, G.V, Sklenar, G, Dales, D, Hammond, G.L, Muller, Y.A. | Deposit date: | 1999-09-28 | Release date: | 2000-06-28 | Last modified: | 2018-01-31 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Crystal structure of human sex hormone-binding globulin: steroid transport by a laminin G-like domain. EMBO J., 19, 2000
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5OM5
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5OM2
| Crystal structure of Alpha1-antichymotrypsin variant DBS-I1: a drug-binding serpin for doxycycline | Descriptor: | (4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE, 1,2-ETHANEDIOL, Alpha-1-antichymotrypsin | Authors: | Schmidt, K, Muller, Y.A. | Deposit date: | 2017-07-28 | Release date: | 2018-05-23 | Last modified: | 2018-06-06 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Design of an allosterically modulated doxycycline and doxorubicin drug-binding protein. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5OM7
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5OM3
| Crystal structure of Alpha1-antichymotrypsin variant DBS-I5: a MMP14-cleavable drug-binding serpin for doxycycline | Descriptor: | (4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE, Alpha-1-antichymotrypsin, DI(HYDROXYETHYL)ETHER | Authors: | Schmidt, K, Muller, Y.A. | Deposit date: | 2017-07-28 | Release date: | 2018-05-23 | Last modified: | 2018-06-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Design of an allosterically modulated doxycycline and doxorubicin drug-binding protein. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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4WWC
| Crystal structure of full length YvoA in complex with palindromic operator DNA | Descriptor: | 1,2-ETHANEDIOL, DNA (5'-D(P*CP*AP*GP*TP*GP*GP*TP*CP*TP*AP*GP*AP*CP*CP*AP*CP*TP*GP*G)-3'), HTH-type transcriptional repressor YvoA | Authors: | Grau, F.C, Fillenberg, S.B, Muller, Y.A. | Deposit date: | 2014-11-10 | Release date: | 2015-01-14 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.903 Å) | Cite: | Structural insight into operator dre-sites recognition and effector binding in the GntR/HutC transcription regulator NagR. Nucleic Acids Res., 43, 2015
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4WIC
| Immediate-early 1 protein (IE1) of rhesus macaque cytomegalovirus | Descriptor: | RhUL123 | Authors: | Klingl, S, Scherer, M, Sevvana, M, Muller, Y.A, Stamminger, T. | Deposit date: | 2014-09-25 | Release date: | 2015-07-15 | Last modified: | 2017-09-06 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Controlled crystal dehydration triggers a space-group switch and shapes the tertiary structure of cytomegalovirus immediate-early 1 (IE1) protein. Acta Crystallogr.,Sect.D, 71, 2015
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4U0V
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4U0W
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4U0Y
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