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1BJ1
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BU of 1bj1 by Molmil
VASCULAR ENDOTHELIAL GROWTH FACTOR IN COMPLEX WITH A NEUTRALIZING ANTIBODY
Descriptor: Fab fragment, heavy chain, light chain, ...
Authors:Muller, Y.A, Christinger, H.W, De Vos, A.M.
Deposit date:1998-06-30
Release date:1999-01-13
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:VEGF and the Fab fragment of a humanized neutralizing antibody: crystal structure of the complex at 2.4 A resolution and mutational analysis of the interface.
Structure, 6, 1998
1A21
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BU of 1a21 by Molmil
TISSUE FACTOR (TF) FROM RABBIT
Descriptor: TISSUE FACTOR
Authors:Muller, Y.A, De Vos, A.M.
Deposit date:1998-01-14
Release date:1998-05-27
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Hinge bending within the cytokine receptor superfamily revealed by the 2.4 A crystal structure of the extracellular domain of rabbit tissue factor.
Protein Sci., 7, 1998
1POW
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BU of 1pow by Molmil
THE REFINED STRUCTURES OF A STABILIZED MUTANT AND OF WILD-TYPE PYRUVATE OXIDASE FROM LACTOBACILLUS PLANTARUM
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, PYRUVATE OXIDASE, ...
Authors:Muller, Y.A, Schulz, G.E.
Deposit date:1993-11-09
Release date:1994-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The refined structures of a stabilized mutant and of wild-type pyruvate oxidase from Lactobacillus plantarum.
J.Mol.Biol., 237, 1994
1POX
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BU of 1pox by Molmil
THE REFINED STRUCTURES OF A STABILIZED MUTANT AND OF WILD-TYPE PYRUVATE OXIDASE FROM LACTOBACILLUS PLANTARUM
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, MAGNESIUM ION, ...
Authors:Muller, Y.A, Schulz, G.E.
Deposit date:1993-11-09
Release date:1994-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The refined structures of a stabilized mutant and of wild-type pyruvate oxidase from Lactobacillus plantarum.
J.Mol.Biol., 237, 1994
2HFT
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BU of 2hft by Molmil
THE CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF HUMAN TISSUE FACTOR AT 1.7 ANGSTROMS RESOLUTION
Descriptor: HUMAN TISSUE FACTOR, SULFATE ION
Authors:Muller, Y.A, De Vos, A.M.
Deposit date:1995-09-08
Release date:1996-01-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:The crystal structure of the extracellular domain of human tissue factor refined to 1.7 A resolution.
J.Mol.Biol., 256, 1996
2VPF
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BU of 2vpf by Molmil
VASCULAR ENDOTHELIAL GROWTH FACTOR REFINED TO 1.93 ANGSTROMS RESOLUTION
Descriptor: VASCULAR ENDOTHELIAL GROWTH FACTOR
Authors:Muller, Y.A, De Vos, A.M.
Deposit date:1997-07-29
Release date:1998-07-29
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:The crystal structure of vascular endothelial growth factor (VEGF) refined to 1.93 A resolution: multiple copy flexibility and receptor binding.
Structure, 5, 1997
1VPF
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BU of 1vpf by Molmil
STRUCTURE OF HUMAN VASCULAR ENDOTHELIAL GROWTH FACTOR
Descriptor: VASCULAR ENDOTHELIAL GROWTH FACTOR
Authors:Muller, Y.A, De Vos, A.M.
Deposit date:1997-04-08
Release date:1998-04-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Vascular endothelial growth factor: crystal structure and functional mapping of the kinase domain receptor binding site.
Proc.Natl.Acad.Sci.USA, 94, 1997
1MJV
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BU of 1mjv by Molmil
DISULFIDE DEFICIENT MUTANT OF VASCULAR ENDOTHELIAL GROWTH FACTOR A (C51A and C60A)
Descriptor: Vascular Endothelial Growth Factor A
Authors:Muller, Y.A, Heiring, C, Misselwitz, R, Welfle, K, Welfle, H.
Deposit date:2002-08-28
Release date:2002-12-11
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The cystine knot promotes folding and not thermodynamic stability in vascular endothelial growth factor
J.Biol.Chem., 277, 2002
1MKK
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BU of 1mkk by Molmil
Disulfide deficient mutant of vascular endothelial growth factor A (C61A and C104A)
Descriptor: Vascular Endothelial Growth Factor A
Authors:Muller, Y.A, Heiring, C, Misselwitz, R, Welfle, K, Welfle, H.
Deposit date:2002-08-29
Release date:2002-12-11
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:The cystine knot promotes folding and not thermodynamic stability in vascular endothelial growth factor
J.Biol.Chem., 277, 2002
1MKG
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BU of 1mkg by Molmil
DISULFIDE DEFICIENT MUTANT OF VASCULAR ENDOTHELIAL GROWTH FACTOR A (C57A and C102A)
Descriptor: Vascular Endothelial Growth Factor A
Authors:Muller, Y.A, Heiring, C, Misselwitz, R, Welfle, K, Welfle, H.
Deposit date:2002-08-29
Release date:2002-12-11
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The cystine knot promotes folding and not thermodynamic stability in vascular endothelial growth factor
J.Biol.Chem., 277, 2002
6T3X
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BU of 6t3x by Molmil
Crystal structure of the truncated human cytomegalovirus pUL50-pUL53 complex
Descriptor: Nuclear egress protein 2,Nuclear egress protein 1
Authors:Muller, Y.A.
Deposit date:2019-10-11
Release date:2020-02-12
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:High-resolution crystal structures of two prototypical beta- and gamma-herpesviral nuclear egress complexes unravel the determinants of subfamily specificity.
J.Biol.Chem., 295, 2020
6T3Z
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BU of 6t3z by Molmil
Crystal structure of the truncated EBV BFRF1-BFLF2 nuclear egress complex
Descriptor: MALONATE ION, Nuclear egress protein 2,Nuclear egress protein 1
Authors:Muller, Y.A.
Deposit date:2019-10-11
Release date:2020-02-12
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.55862784 Å)
Cite:High-resolution crystal structures of two prototypical beta- and gamma-herpesviral nuclear egress complexes unravel the determinants of subfamily specificity.
J.Biol.Chem., 295, 2020
6EL3
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BU of 6el3 by Molmil
Structure of Progesterone 5beta-Reductase from Arabidopsis thaliana in complex with NADP
Descriptor: 3-oxo-Delta(4,5)-steroid 5-beta-reductase, CHLORIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Muller, Y.A, Schmidt, K, Egerer-Sieber, C.
Deposit date:2017-09-27
Release date:2018-09-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.899 Å)
Cite:PRISEs (progesterone 5 beta-reductase and/or iridoid synthase-like 1,4-enone reductases): Catalytic and substrate promiscuity allows for realization of multiple pathways in plant metabolism.
Phytochemistry, 156, 2018
4WID
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BU of 4wid by Molmil
Crystal structure of the immediate-early 1 protein (IE1) at 2.31 angstrom (tetragonal form after crystal dehydration)
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, RhUL123
Authors:Klingl, S, Scherer, M, Sevvana, M, Muller, Y.A, Stamminger, T.
Deposit date:2014-09-25
Release date:2014-10-29
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Crystal Structure of Cytomegalovirus IE1 Protein Reveals Targeting of TRIM Family Member PML via Coiled-Coil Interactions.
Plos Pathog., 10, 2014
4WWC
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BU of 4wwc by Molmil
Crystal structure of full length YvoA in complex with palindromic operator DNA
Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(P*CP*AP*GP*TP*GP*GP*TP*CP*TP*AP*GP*AP*CP*CP*AP*CP*TP*GP*G)-3'), HTH-type transcriptional repressor YvoA
Authors:Grau, F.C, Fillenberg, S.B, Muller, Y.A.
Deposit date:2014-11-10
Release date:2015-01-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.903 Å)
Cite:Structural insight into operator dre-sites recognition and effector binding in the GntR/HutC transcription regulator NagR.
Nucleic Acids Res., 43, 2015
4WIC
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BU of 4wic by Molmil
Immediate-early 1 protein (IE1) of rhesus macaque cytomegalovirus
Descriptor: RhUL123
Authors:Klingl, S, Scherer, M, Sevvana, M, Muller, Y.A, Stamminger, T.
Deposit date:2014-09-25
Release date:2015-07-15
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Controlled crystal dehydration triggers a space-group switch and shapes the tertiary structure of cytomegalovirus immediate-early 1 (IE1) protein.
Acta Crystallogr.,Sect.D, 71, 2015
1F5F
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BU of 1f5f by Molmil
CRYSTAL STRUCTURE OF THE N-TERMINAL G-DOMAIN OF SHBG IN COMPLEX WITH ZINC
Descriptor: 5-ALPHA-DIHYDROTESTOSTERONE, CALCIUM ION, ISOPROPYL ALCOHOL, ...
Authors:Avvakumov, V.A, Muller, Y.A, Hammond, G.L.
Deposit date:2000-06-14
Release date:2000-09-06
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Steroid-binding specificity of human sex hormone-binding globulin is influenced by occupancy of a zinc-binding site.
J.Biol.Chem., 275, 2000
5OM6
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BU of 5om6 by Molmil
Crystal structure of Alpha1-antichymotrypsin variant DBS-I-allo2: a MMP9-cleavable drug-binding serpin for doxycycline
Descriptor: 1,2-ETHANEDIOL, Alpha-1-antichymotrypsin, CHLORIDE ION, ...
Authors:Schmidt, K, Muller, Y.A.
Deposit date:2017-07-28
Release date:2018-05-23
Last modified:2018-06-06
Method:X-RAY DIFFRACTION (1.849 Å)
Cite:Design of an allosterically modulated doxycycline and doxorubicin drug-binding protein.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5OM8
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BU of 5om8 by Molmil
Crystal form 2 of Alpha1-antichymotrypsin variant DBS-II-allo: an allosterically modulated drug-binding serpin for doxorubicin
Descriptor: 1,2-ETHANEDIOL, Alpha-1-antichymotrypsin, CHLORIDE ION, ...
Authors:Schmidt, K, Muller, Y.A.
Deposit date:2017-07-28
Release date:2018-05-23
Last modified:2018-06-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Design of an allosterically modulated doxycycline and doxorubicin drug-binding protein.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5C05
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BU of 5c05 by Molmil
Crystal Structure of Gamma-terpinene Synthase from Thymus vulgaris
Descriptor: 1,2-ETHANEDIOL, Putative gamma-terpinene synthase
Authors:Parthier, C.P, Rudolph, K, Muller, Y.A, Mueller-Uri, F.
Deposit date:2015-06-12
Release date:2016-01-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Expression, crystallization and structure elucidation of gamma-terpinene synthase from Thymus vulgaris.
Acta Crystallogr.,Sect.F, 72, 2016
5OM5
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BU of 5om5 by Molmil
Crystal structure of Alpha1-antichymotrypsin variant DBS-I-allo1: an allosterically triggered drug-binding serpin for doxycycline
Descriptor: 1,2-ETHANEDIOL, Alpha-1-antichymotrypsin, CHLORIDE ION
Authors:Schmidt, K, Muller, Y.A.
Deposit date:2017-07-28
Release date:2018-05-23
Last modified:2018-06-06
Method:X-RAY DIFFRACTION (1.595 Å)
Cite:Design of an allosterically modulated doxycycline and doxorubicin drug-binding protein.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5OM2
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BU of 5om2 by Molmil
Crystal structure of Alpha1-antichymotrypsin variant DBS-I1: a drug-binding serpin for doxycycline
Descriptor: (4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE, 1,2-ETHANEDIOL, Alpha-1-antichymotrypsin
Authors:Schmidt, K, Muller, Y.A.
Deposit date:2017-07-28
Release date:2018-05-23
Last modified:2018-06-06
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Design of an allosterically modulated doxycycline and doxorubicin drug-binding protein.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5OM7
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BU of 5om7 by Molmil
Crystal structure of Alpha1-antichymotrypsin variant DBS-II: a drug-binding serpin for doxorubicin
Descriptor: Alpha-1-antichymotrypsin, DOXORUBICIN
Authors:Schmidt, K, Kern, A, Muller, Y.A.
Deposit date:2017-07-28
Release date:2018-05-23
Last modified:2018-06-06
Method:X-RAY DIFFRACTION (1.727 Å)
Cite:Design of an allosterically modulated doxycycline and doxorubicin drug-binding protein.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5OM3
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BU of 5om3 by Molmil
Crystal structure of Alpha1-antichymotrypsin variant DBS-I5: a MMP14-cleavable drug-binding serpin for doxycycline
Descriptor: (4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE, Alpha-1-antichymotrypsin, DI(HYDROXYETHYL)ETHER
Authors:Schmidt, K, Muller, Y.A.
Deposit date:2017-07-28
Release date:2018-05-23
Last modified:2018-06-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Design of an allosterically modulated doxycycline and doxorubicin drug-binding protein.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
1D2S
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BU of 1d2s by Molmil
CRYSTAL STRUCTURE OF THE N-TERMINAL LAMININ G-LIKE DOMAIN OF SHBG IN COMPLEX WITH DIHYDROTESTOSTERONE
Descriptor: 5-ALPHA-DIHYDROTESTOSTERONE, CALCIUM ION, SEX HORMONE-BINDING GLOBULIN
Authors:Grishkovskaya, I, Avvakumov, G.V, Sklenar, G, Dales, D, Hammond, G.L, Muller, Y.A.
Deposit date:1999-09-28
Release date:2000-06-28
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structure of human sex hormone-binding globulin: steroid transport by a laminin G-like domain.
EMBO J., 19, 2000

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