Author results

2HPE
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COMPARISON OF THE STRUCTURES OF HIV-2 PROTEASE COMPLEXES IN THREE CRYSTAL SPACE GROUPS WITH AN HIV-1 PROTEASE COMPLEX STRUCTURE
Descriptor:HIV-2 PROTEASE, UNIDENTIFIED PEPTIDE FRAGMENT
Authors:Mulichak, A.M., Watenpaugh, K.D.
Deposit date:1994-09-21
Release date:1994-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Comparison of the Structures of HIV-2 Protease Complexes in Three Crystal Space Groups with an HIV-1 Protease Complex Structure
To be Published
2HPF
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COMPARISON OF THE STRUCTURES OF HIV-2 PROTEASE COMPLEXES IN THREE CRYSTAL SPACE GROUPS WITH AN HIV-1 PROTEASE COMPLEX STRUCTURE
Descriptor:HIV-2 PROTEASE, UNIDENTIFIED PEPTIDE FRAGMENT
Authors:Mulichak, A.M., Watenpaugh, K.D.
Deposit date:1994-09-21
Release date:1994-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Comparison of the Structures of HIV-2 Protease Complexes in Three Crystal Space Groups with an HIV-1 Protease Complex Structure
To be Published
2Q3F
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X-RAY CRYSTAL STRUCTURE OF PUTATIVE HUMAN RAS-RELATED GTP BINDING D IN COMPLEX WITH GMPPNP
Descriptor:Ras-related GTP-binding protein D, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Mulichak, A.M., Rabeh, W.M., Tempel, W., Nedyalkova, L., Landry, R., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Keefe, L.J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2007-05-30
Release date:2007-06-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of human Ras-related GTP-binding D.
To be published
1BDG
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HEXOKINASE FROM SCHISTOSOMA MANSONI COMPLEXED WITH GLUCOSE
Descriptor:HEXOKINASE, ALPHA-D-GLUCOSE, SULFATE ION
Authors:Mulichak, A.M., Garavito, R.M.
Deposit date:1998-05-08
Release date:1999-05-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The structure of mammalian hexokinase-1.
Nat.Struct.Biol., 5, 1998
1BG3
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RAT BRAIN HEXOKINASE TYPE I COMPLEX WITH GLUCOSE AND INHIBITOR GLUCOSE-6-PHOSPHATE
Descriptor:HEXOKINASE, BETA-D-GLUCOSE, ALPHA-D-GLUCOSE-6-PHOSPHATE, ...
Authors:Mulichak, A.M., Garavito, R.M.
Deposit date:1998-06-04
Release date:1999-06-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The structure of mammalian hexokinase-1.
Nat.Struct.Biol., 5, 1998
1IIR
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CRYSTAL STRUCTURE OF UDP-GLUCOSYLTRANSFERASE GTFB
Descriptor:glycosyltransferase GtfB, SULFATE ION, MAGNESIUM ION
Authors:Mulichak, A.M., Losey, H.C., Walsh, C.T., Garavito, R.M.
Deposit date:2001-04-24
Release date:2001-07-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of the UDP-glucosyltransferase GtfB that modifies the heptapeptide aglycone in the biosynthesis of vancomycin group antibiotics.
Structure, 9, 2001
1IVP
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THE CRYSTALLOGRAPHIC STRUCTURE OF THE PROTEASE FROM HUMAN IMMUNODEFICIENCY VIRUS TYPE 2 WITH TWO SYNTHETIC PEPTIDIC TRANSITION STATE ANALOG INHIBITORS
Descriptor:HIV-2 PROTEASE, 4-[(2R)-3-{[(1S,2S,3R,4S)-1-(cyclohexylmethyl)-2,3-dihydroxy-5-methyl-4-({(1S,2R)-2-methyl-1-[(pyridin-2-ylmethyl)carbamoyl]butyl}carbamoyl)hexyl]amino}-2-{[(naphthalen-1-yloxy)acetyl]amino}-3-oxopropyl]-1H-imidazol-3-ium
Authors:Mulichak, A.M., Watenpaugh, K.D.
Deposit date:1993-03-18
Release date:1993-07-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystallographic structure of the protease from human immunodeficiency virus type 2 with two synthetic peptidic transition state analog inhibitors.
J.Biol.Chem., 268, 1993
1IVQ
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THE CRYSTALLOGRAPHIC STRUCTURE OF THE PROTEASE FROM HUMAN IMMUNODEFICIENCY VIRUS TYPE 2 WITH TWO SYNTHETIC PEPTIDIC TRANSITION STATE ANALOG INHIBITORS
Descriptor:HIV-2 PROTEASE, N~1~-{(1S,2S,4S)-1-(cyclohexylmethyl)-4-[(2,2-dimethylpropyl)carbamoyl]-2-hydroxy-5-methylhexyl}-N~2~-(quinolin-2-ylcarbonyl)-L-aspartamide
Authors:Mulichak, A.M., Watenpaugh, K.D.
Deposit date:1993-03-18
Release date:1993-07-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The crystallographic structure of the protease from human immunodeficiency virus type 2 with two synthetic peptidic transition state analog inhibitors.
J.Biol.Chem., 268, 1993
1N7G
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CRYSTAL STRUCTURE OF THE GDP-MANNOSE 4,6-DEHYDRATASE TERNARY COMPLEX WITH NADPH AND GDP-RHAMNOSE.
Descriptor:GDP-D-mannose-4,6-dehydratase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, GUANOSINE-5'-DIPHOSPHATE-RHAMNOSE
Authors:Mulichak, A.M., Bonin, C.P., Reiter, W.-D., Garavito, R.M.
Deposit date:2002-11-14
Release date:2003-01-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structure of the MUR1 GDP-mannose 4,6-dehydratase from A. thaliana: Implications for ligand binding and specificity.
Biochemistry, 41, 2002
1N7H
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CRYSTAL STRUCTURE OF GDP-MANNOSE 4,6-DEHYDRATASE TERNARY COMPLEX WITH NADPH AND GDP
Descriptor:GDP-D-mannose-4,6-dehydratase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, GUANOSINE-5'-DIPHOSPHATE
Authors:Mulichak, A.M., Bonin, C.P., Reiter, W.-D., Garavito, R.M.
Deposit date:2002-11-14
Release date:2003-01-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structure of the MUR1 GDP-mannose 4,6-dehydratase from A. thaliana: Implications for ligand binding and specificity.
Biochemistry, 41, 2002
1PN3
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CRYSTAL STRUCTURE OF TDP-EPI-VANCOSAMINYLTRANSFERASE GTFA IN COMPLEXES WITH TDP AND THE ACCEPTOR SUBSTRATE DVV.
Descriptor:GLYCOSYLTRANSFERASE GTFA, DESVANCOSAMINYL VANCOMYCIN, THYMIDINE-5'-DIPHOSPHATE, ...
Authors:Mulichak, A.M., Losey, H.C., Lu, W., Wawrzak, Z., Walsh, C.T., Garavito, R.M.
Deposit date:2003-06-12
Release date:2003-08-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the Tdp-Epi-Vancosaminyltransferase Gtfa from the Chloroeremomycin Biosynthetic Pathway.
Proc.Natl.Acad.Sci.USA, 100, 2003
1PNV
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CRYSTAL STRUCTURE OF TDP-EPI-VANCOSAMINYLTRANSFERASE GTFA IN COMPLEXES WITH TDP AND VANCOMYCIN
Descriptor:GLYCOSYLTRANSFERASE GTFA, VANCOMYCIN, THYMIDINE-5'-DIPHOSPHATE, ...
Authors:Mulichak, A.M., Losey, H.C., Lu, W., Wawrzak, Z., Walsh, C.T., Garavito, R.M.
Deposit date:2003-06-13
Release date:2003-08-12
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the Tdp-Epi-Vancosaminyltransferase Gtfa from the Chloroeremomycin Biosynthetic Pathway.
Proc.Natl.Acad.Sci.USA, 100, 2003
1QRR
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CRYSTAL STRUCTURE OF SQD1 PROTEIN COMPLEX WITH NAD AND UDP-GLUCOSE
Descriptor:sulfolipid biosynthesis (SQD1) PROTEIN, SULFATE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Mulichak, A.M., Theisen, M.J., Essigmann, B., Benning, C., Garavito, R.M.
Deposit date:1999-06-15
Release date:1999-11-10
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of SQD1, an enzyme involved in the biosynthesis of the plant sulfolipid headgroup donor UDP-sulfoquinovose.
Proc.Natl.Acad.Sci.USA, 96, 1999
1RRV
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X-RAY CRYSTAL STRUCTURE OF TDP-VANCOSAMINYLTRANSFERASE GTFD AS A COMPLEX WITH TDP AND THE NATURAL SUBSTRATE, DESVANCOSAMINYL VANCOMYCIN.
Descriptor:GLYCOSYLTRANSFERASE GTFD, DESVANCOSAMINYL VANCOMYCIN, POTASSIUM ION, ...
Authors:Mulichak, A.M., Lu, W., Losey, H.C., Walsh, C.T., Garavito, R.M.
Deposit date:2003-12-09
Release date:2004-05-18
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Vancosaminyltransferase Gtfd from the Vancomycin Biosynthetic Pathway: Interactions with Acceptor and Nucleotide Ligands
Biochemistry, 43, 2004
1TA9
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CRYSTAL STRUCTURE OF GLYCEROL DEHYDROGENASE FROM SCHIZOSACCHAROMYCES POMBE
Descriptor:glycerol dehydrogenase, ZINC ION, POTASSIUM ION, ...
Authors:Mulichak, A.M.
Deposit date:2004-05-19
Release date:2005-08-16
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of glycerol dehydrogenase from Schyzosaccharomyces pombe
To be Published
2GQF
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CRYSTAL STRUCTURE OF FLAVOPROTEIN HI0933 FROM HAEMOPHILUS INFLUENZAE RD
Descriptor:Hypothetical protein HI0933, SULFATE ION, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Mulichak, A.M., Patskovsky, Y., Keefe, L.J., Almo, S.C., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2006-04-20
Release date:2006-05-30
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of hypothetical flavoprotein HI0933 from Haemophilus influenzae Rd.
To be Published
4HL7
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CRYSTAL STRUCTURE OF NICOTINATE PHOSPHORIBOSYLTRANSFERASE (TARGET NYSGR-026035) FROM VIBRIO CHOLERAE
Descriptor:Nicotinate phosphoribosyltransferase, SULFATE ION
Authors:Mulichak, A.M., Sauder, J.M., Keefe, L.J., Burley, S.K., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2012-10-16
Release date:2012-11-14
Last modified:2018-11-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of nicotinate phosphoribosyltransferase (target NYSGR-026035) from Vibrio cholerae
To be Published
1PK4
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CRYSTAL AND MOLECULAR STRUCTURE OF HUMAN PLASMINOGEN KRINGLE 4 REFINED AT 1.9-ANGSTROMS RESOLUTION
Descriptor:PLASMINOGEN KRINGLE 4, SULFATE ION
Authors:Tulinsky, A., Mulichak, A.M.
Deposit date:1991-07-18
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal and molecular structure of human plasminogen kringle 4 refined at 1.9-A resolution.
Biochemistry, 30, 1991
4DC5
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CRYSTAL STRUCTURE OF THAUMATIN UNEXPOSED TO EXCESSIVE SONICC IMAGING LASER DOSE.
Descriptor:Thaumatin I, L(+)-TARTARIC ACID, GLYCEROL
Authors:Mulichak, A.M., Becker, M., Kissick, D.J., Keefe, L.J., Fischetti, R.F., Simpson, G.J.
Deposit date:2012-01-17
Release date:2013-01-23
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Towards protein-crystal centering using second-harmonic generation (SHG) microscopy.
Acta Crystallogr.,Sect.D, 69, 2013
4DC6
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CRYSTAL STRUCTURE OF THAUMATIN EXPOSED TO EXCESSIVE SONICC IMAGING LASER DOSE.
Descriptor:Thaumatin I, L(+)-TARTARIC ACID, GLYCEROL
Authors:Mulichak, A.M., Becker, M., Kissick, D.J., Keefe, L.J., Fischetti, R.F., Simpson, G.J.
Deposit date:2012-01-17
Release date:2013-01-23
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Towards protein-crystal centering using second-harmonic generation (SHG) microscopy.
Acta Crystallogr.,Sect.D, 69, 2013
1RPN
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CRYSTAL STRUCTURE OF GDP-D-MANNOSE 4,6-DEHYDRATASE IN COMPLEXES WITH GDP AND NADPH
Descriptor:GDP-mannose 4,6-dehydratase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, GUANOSINE-5'-DIPHOSPHATE
Authors:Webb, N.A., Mulichak, A.M., Lam, J.S., Rocchetta, H.L., Garavito, R.M.
Deposit date:2003-12-03
Release date:2004-02-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structure of a tetrameric GDP-D-mannose 4,6-dehydratase from a bacterial GDP-D-rhamnose biosynthetic pathway.
Protein Sci., 13, 2004
1UPJ
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HIV-1 PROTEASE COMPLEX WITH U095438 [3-[1-(4-BROMOPHENYL) ISOBUTYL]-4-HYDROXYCOUMARIN
Descriptor:HIV-1 PROTEASE, 3-[1-(4-BROMO-PHENYL)-2-METHYL-PROPYL]-4-HYDROXY-CHROMEN-2-ONE
Authors:Watenpaugh, K.D., Mulichak, A.M., Janakiraman, M.N.
Deposit date:1996-03-04
Release date:1996-10-14
Last modified:2012-02-22
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Structure-based design of novel HIV protease inhibitors: carboxamide-containing 4-hydroxycoumarins and 4-hydroxy-2-pyrones as potent nonpeptidic inhibitors.
J.Med.Chem., 38, 1995
2UPJ
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HIV-1 PROTEASE COMPLEX WITH U100313 ([3-[[3-[CYCLOPROPYL [4-HYDROXY-2OXO-6-[1-(PHENYLMETHYL)PROPYL]-2H-PYRAN-3-YL] METHYL]PHENYL]AMINO]-3-OXO-PROPYL]CARBAMIC ACID TERT-BUTYL ESTER)
Descriptor:HIV-1 PROTEASE, [2-(3-{[6-(1-BENZYL-PROPYL)-4-HYDROXY-2-OXO-2H-PYRAN-3-YL]-CYCLOPROPYL-METHYL}-PHENYLCARBAMOYL)-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER
Authors:Watenpaugh, K.D., Mulichak, A.M., Janakiraman, M.N.
Deposit date:1996-03-04
Release date:1996-10-14
Last modified:2012-02-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure-based design of novel HIV protease inhibitors: carboxamide-containing 4-hydroxycoumarins and 4-hydroxy-2-pyrones as potent nonpeptidic inhibitors.
J.Med.Chem., 38, 1995
3UPJ
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HUMAN IMMUNODEFICIENCY VIRUS TYPE 2 PROTEASE MUTANT WITH LYS 57 REPLACED BY LEU (K57L) COMPLEX WITH U096333 [4-HYDROXY-3-[1-(PHENYL)PROPYL]-7-METHOXYCOUMARIN]
Descriptor:HIV-2 PROTEASE, 4-HYDROXY-7-METHOXY-3-(1-PHENYL-PROPYL)-CHROMEN-2-ONE
Authors:Watenpaugh, K.D., Mulichak, A.M., Janakiraman, M.N.
Deposit date:1996-03-04
Release date:1996-10-14
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure-based design of novel HIV protease inhibitors: carboxamide-containing 4-hydroxycoumarins and 4-hydroxy-2-pyrones as potent nonpeptidic inhibitors.
J.Med.Chem., 38, 1995
4DC7
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CRYSTAL STRUCTURE OF MYOGLOBIN EXPOSED TO EXCESSIVE SONICC IMAGING LASER DOSE.
Descriptor:Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
Authors:Becker, M., Mulichak, A.M., Kissick, D.J., Fischetti, R.F., Keefe, L.J., Simpson, G.J.
Deposit date:2012-01-17
Release date:2013-01-23
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Towards protein-crystal centering using second-harmonic generation (SHG) microscopy.
Acta Crystallogr.,Sect.D, 69, 2013
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