1IFY
 
 | |
1P98
 | |
1P9D
 | |
1P9C
 | |
1RAX
 | |
1WAQ
 | |
3BK3
 | |
5DR5
 | | Crystal structure of the sclerostin-neutralizing Fab AbD09097 | | Descriptor: | AbD09097 Fab heavy chain, AbD09097 Fab light chain | | Authors: | Mueller, T.D, Boschert, V, Weidauer, S.E, Muth, E.M, Knappik, A, Frisch, C. | | Deposit date: | 2015-09-15 | | Release date: | 2016-08-31 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Generation and Affinity Maturation of Neutralizing Anti-Sclerostin Antibodies
to be published
|
|
6H41
 | |
3B5K
 | |
2H62
 | | Crystal structure of a ternary ligand-receptor complex of BMP-2 | | Descriptor: | Acvr2b protein, Bone morphogenetic protein 2, Bone morphogenetic protein receptor type IA | | Authors: | Mueller, T.D. | | Deposit date: | 2006-05-30 | | Release date: | 2007-04-10 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | A silent H-bond can be mutationally activated for high-affinity interaction of BMP-2 and activin type IIB receptor.
Bmc Struct.Biol., 7, 2007
|
|
2H64
 | |
3NH7
 | | Crystal structure of the neutralizing Fab fragment AbD1556 bound to the BMP type I receptor IA | | Descriptor: | Antibody fragment Fab AbD1556, heavy chain, light chain, ... | | Authors: | Mueller, T.D, Harth, S, Sebald, W. | | Deposit date: | 2010-06-14 | | Release date: | 2010-10-27 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | A selection fit mechanism in BMP receptor IA as a possible source for BMP ligand-receptor promiscuity
Plos One, 5, 2010
|
|
3QB4
 | |
3QT2
 | | Structure of a cytokine ligand-receptor complex | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Interleukin-5, Interleukin-5 receptor subunit alpha, ... | | Authors: | Mueller, T.D, Patino, E, Kotzsch, A, Saremba, S, Nickel, J, Schmitz, W, Sebald, W. | | Deposit date: | 2011-02-22 | | Release date: | 2012-02-01 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Structure Analysis of the IL-5 Ligand-Receptor Complex Reveals a Wrench-like Architecture for IL-5Ralpha.
Structure, 19, 2011
|
|
2MBK
 | | The Clip-segment of the von Willebrand domain 1 of the BMP modulator protein Crossveinless 2 is preformed | | Descriptor: | Crossveinless 2 | | Authors: | Mueller, T.D, Fiebig, J.E, Weidauer, S.E, Qiu, L, Bauer, M, Schmieder, P, Beerbaum, M, Zhang, J, Oschkinat, H, Sebald, W. | | Deposit date: | 2013-08-02 | | Release date: | 2013-10-16 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | The Clip-Segment of the von Willebrand Domain 1 of the BMP Modulator Protein Crossveinless 2 Is Preformed.
Molecules, 18, 2013
|
|
2R53
 | |
2R52
 | |
3SS9
 | | Crystal structure of holo D-serine dehydratase from Escherichia coli at 1.97 A resolution | | Descriptor: | D-serine dehydratase, POTASSIUM ION, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Urusova, D.V, Isupov, M.N, Antonyuk, S.V, Kachalova, G.S, Vagin, A.A, Lebedev, A.A, Bourenkov, G.P, Dauter, Z, Bartunik, H.D, Melik-Adamyan, W.R, Mueller, T.D, Schnackerz, K.D. | | Deposit date: | 2011-07-08 | | Release date: | 2012-01-18 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | Crystal structure of D-serine dehydratase from Escherichia coli.
Biochim.Biophys.Acta, 1824, 2011
|
|
3SS7
 | | Crystal structure of holo D-serine dehydratase from Escherichia coli at 1.55 A resolution | | Descriptor: | D-serine dehydratase, GLYCEROL, POTASSIUM ION, ... | | Authors: | Urusova, D.V, Isupov, M.N, Antonyuk, S.V, Kachalova, G.S, Vagin, A.A, Lebedev, A.A, Bourenkov, G.P, Dauter, Z, Bartunik, H.D, Melik-Adamyan, W.R, Mueller, T.D, Schnackerz, K.D. | | Deposit date: | 2011-07-07 | | Release date: | 2012-01-18 | | Last modified: | 2012-02-08 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Crystal structure of D-serine dehydratase from Escherichia coli.
Biochim.Biophys.Acta, 1824, 2011
|
|
1DV0
 | |
1F4I
 | | SOLUTION STRUCTURE OF THE HHR23A UBA(2) MUTANT P333E, DEFICIENT IN BINDING THE HIV-1 ACCESSORY PROTEIN VPR | | Descriptor: | UV EXCISION REPAIR PROTEIN PROTEIN RAD23 HOMOLOG A | | Authors: | Withers-Ward, E.S, Mueller, T.D, Chen, I.S, Feigon, J. | | Deposit date: | 2000-06-07 | | Release date: | 2000-12-20 | | Last modified: | 2021-11-03 | | Method: | SOLUTION NMR | | Cite: | Biochemical and structural analysis of the interaction between the UBA(2) domain of the DNA repair protein HHR23A and HIV-1 Vpr.
Biochemistry, 39, 2000
|
|
2B90
 | | Crystal structure of the interleukin-4 variant T13DR85A | | Descriptor: | Interleukin-4, SULFATE ION | | Authors: | Kraich, M, Klein, M, Patino, E, Harrer, H, Sebald, W, Mueller, T.D. | | Deposit date: | 2005-10-10 | | Release date: | 2006-05-30 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | A modular interface of IL-4 allows for scalable affinity without affecting specificity for the IL-4 receptor
Bmc Biol., 4, 2006
|
|
2B8U
 | | Crystal structure of wildtype human Interleukin-4 | | Descriptor: | Interleukin-4, SULFATE ION | | Authors: | Kraich, M, Klein, M, Patino, E, Harrer, H, Sebald, W, Mueller, T.D. | | Deposit date: | 2005-10-10 | | Release date: | 2006-05-30 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | A modular interface of IL-4 allows for scalable affinity without affecting specificity for the IL-4 receptor
Bmc Biol., 4, 2006
|
|
2B8Y
 | | Crystal structure of the interleukin-4 variant T13DF82D | | Descriptor: | Interleukin-4, SULFATE ION | | Authors: | Kraich, M, Klein, M, Patino, E, Harrer, H, Sebald, W, Mueller, T.D. | | Deposit date: | 2005-10-10 | | Release date: | 2006-05-30 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | A modular interface of IL-4 allows for scalable affinity without affecting specificity for the IL-4 receptor
Bmc Biol., 4, 2006
|
|
