Author results

1LXL
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NMR STRUCTURE OF BCL-XL, AN INHIBITOR OF PROGRAMMED CELL DEATH, MINIMIZED AVERAGE STRUCTURE
分子名称:BCL-XL
著者Muchmore, S.W., Sattler, M., Liang, H., Meadows, R.P., Harlan, J.E., Yoon, H.S., Nettesheim, D., Chang, B.S., Thompson, C.B., Wong, S.L., Ng, S.C., Fesik, S.W.
登録日1996-04-04
公開日1997-04-21
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death.
Nature, 381, 1996
1MAZ
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X-RAY STRUCTURE OF BCL-XL, AN INHIBITOR OF PROGRAMMED CELL DEATH
分子名称:Bcl-2-like protein 1
著者Muchmore, S.W., Sattler, M., Liang, H., Meadows, R.P., Harlan, J.E., Yoon, H.S., Nettesheim, D., Chang, B.S., Thompson, C.B., Wong, S.L., Ng, S.C., Fesik, S.W.
登録日1996-04-09
公開日1997-04-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death.
Nature, 381, 1996
1M4M
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MOUSE SURVIVIN
分子名称:BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 5, ZINC ION
著者Muchmore, S.W., Chen, J., Jakob, C., Zakula, D., Matayoshi, E.D., Wu, W., Zhang, H., Li, F., Ng, S.C., Altieri, D.C.
登録日2002-07-03
公開日2002-09-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献CRYSTAL STRUCTURE AND MUTAGENIC ANALYSIS OF THE INHIBITOR-OF-APOPTOSIS PROTEIN SURVIVIN
MOL.CELL, 6, 2000
2I6A
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HUMAN ADENOSINE KINASE IN COMPLEX WITH 5'-DEOXY-5-IODOTUBERCIDIN
分子名称:Adenosine kinase, 7-(5-DEOXY-BETA-D-RIBOFURANOSYL)-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE
著者Muchmore, S.W.
登録日2006-08-28
公開日2007-01-02
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of human adenosine kinase inhibitor complexes reveal two distinct binding modes.
J.Med.Chem., 49, 2006
2I6B
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HUMAN ADENOSINE KINASE IN COMPLEX WITH AN ACETYLINIC INHIBITOR
分子名称:Adenosine kinase, 5-[4-(DIMETHYLAMINO)PHENYL]-6-[(6-MORPHOLIN-4-YLPYRIDIN-3-YL)ETHYNYL]PYRIMIDIN-4-AMINE
著者Muchmore, S.W.
登録日2006-08-28
公開日2007-01-02
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of human adenosine kinase inhibitor complexes reveal two distinct binding modes.
J.Med.Chem., 49, 2006
1NL4
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CRYSTAL STRUCTURE OF RAT FARNESYL TRANSFERASE IN COMPLEX WITH A POTENT BIPHENYL INHIBITOR
分子名称:Protein farnesyltransferase alpha subunit, Protein farnesyltransferase beta subunit, ZINC ION, ...
著者Curtin, M.L., Florjancic, A.S., Cohen, J., Gu, W.-J., Frost, D.J., Muchmore, S.W., Sham, H.L.
登録日2003-01-06
公開日2003-02-11
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Novel and Selective Imidazole-containing Biphenyl Inhibitors of Protein Farnesyltransferase
BIOORG.MED.CHEM.LETT., 13, 2003
1PPA
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THE CRYSTAL STRUCTURE OF A LYSINE 49 PHOSPHOLIPASE A2 FROM THE VENOM OF THE COTTONMOUTH SNAKE AT 2.0 ANGSTROMS RESOLUTION
分子名称:PHOSPHOLIPASE A2, ANILINE
著者Holland, D.R., Clancy, L.L., Muchmore, S.W., Rydel, T.J., Einspahr, H.M., Finzel, B.C., Heinrikson, R.L., Watenpaugh, K.D.
登録日1991-10-29
公開日1994-01-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The crystal structure of a lysine 49 phospholipase A2 from the venom of the cottonmouth snake at 2.0-A resolution.
J.Biol.Chem., 265, 1990
1ZAP
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SECRETED ASPARTIC PROTEASE FROM C. ALBICANS
分子名称:SECRETED ASPARTIC PROTEINASE, ZINC ION, N-ethyl-N-[(4-methylpiperazin-1-yl)carbonyl]-D-phenylalanyl-N-[(1S,2S,4R)-4-(butylcarbamoyl)-1-(cyclohexylmethyl)-2-hydroxy-5-methylhexyl]-L-norleucinamide
著者Abad-Zapatero, C., Muchmore, S.W.
登録日1996-01-16
公開日1997-04-21
最終更新日2012-01-18
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of a secreted aspartic protease from C. albicans complexed with a potent inhibitor: implications for the design of antifungal agents.
Protein Sci., 5, 1996
2ERC
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CRYSTAL STRUCTURE OF ERMC' A RRNA-METHYL TRANSFERASE
分子名称:RRNA METHYL TRANSFERASE
著者Bussiere, D.E., Muchmore, S.W., Dealwis, C.G., Schluckebier, G., Abad-Zapatero, C.
登録日1998-03-13
公開日1999-03-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.03 Å)
主引用文献Crystal structure of ErmC', an rRNA methyltransferase which mediates antibiotic resistance in bacteria.
Biochemistry, 37, 1998
1I1B
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CRYSTAL STRUCTURE OF RECOMBINANT HUMAN INTERLEUKIN-1BETA AT 2.0 ANGSTROMS RESOLUTION
分子名称:INTERLEUKIN-1 BETA
著者Finzel, B.C., Watenpaugh, K.D., Einspahr, H.M.
登録日1989-12-05
公開日1990-01-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of recombinant human interleukin-1 beta at 2.0 A resolution.
J.Mol.Biol., 209, 1989
1HAN
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CRYSTAL STRUCTURE OF THE BIPHENYL-CLEAVING EXTRADIOL DIOXYGENASE FROM A PCB-DEGRADING PSEUDOMONAD
分子名称:2,3-DIHYDROXYBIPHENYL 1,2-DIOXYGENASE, FE (III) ION, TERTIARY-BUTYL ALCOHOL
著者Han, S., Bolin, J.T.
登録日1995-08-30
公開日1995-11-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the biphenyl-cleaving extradiol dioxygenase from a PCB-degrading pseudomonad.
Science, 270, 1995
2WJO
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HUMAN BACE (BETA SECRETASE) IN COMPLEX WITH CYCLOHEXANECARBOXYLIC ACID (2-(2-AM INO-6-PHENOXY-4H-QUINAZOLIN-3-YL)-2 -CYCLOHEXYL-ETHYL)- AMIDE
分子名称:BETA-SECRETASE 1, 2-AMINO-3-{(1R)-1-CYCLOHEXYL-2-[(CYCLOHEXYLCARBONYL)AMINO]ETHYL}-6-PHENOXYQUINAZOLIN-3-IUM
著者Mathieu, M., Dupuy, A.S.
登録日2009-05-28
公開日2010-03-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular Shape and Medicinal Chemistry: A Perspective.
J.Med.Chem., 53, 2010
1KMY
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CRYSTAL STRUCTURE OF 2,3-DIHYDROXYBIPHENYL 1,2-DIOXYGENASE COMPLEXED WITH 2,3-DIHYDROXYBIPHENYL UNDER ANAEROBIC CONDITION
分子名称:2,3-DIHYDROXYBIPHENYL 1,2-DIOXYGENASE, FE (II) ION, BIPHENYL-2,3-DIOL, ...
著者Han, S., Bolin, J.T.
登録日2001-12-17
公開日2002-02-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular basis for the stabilization and inhibition of 2, 3-dihydroxybiphenyl 1,2-dioxygenase by t-butanol.
J.Biol.Chem., 273, 1998
1KND
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CRYSTAL STRUCTURE OF 2,3-DIHYDROXYBIPHENYL 1,2-DIOXYGENASE COMPLEXED WITH CATECHOL UNDER ANAEROBIC CONDITION
分子名称:2,3-DIHYDROXYBIPHENYL 1,2-DIOXYGENASE, FE (II) ION, CATECHOL, ...
著者Han, S., Bolin, J.T.
登録日2001-12-18
公開日2002-03-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Molecular basis for the stabilization and inhibition of 2, 3-dihydroxybiphenyl 1,2-dioxygenase by t-butanol.
J.Biol.Chem., 273, 1998
1KNF
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CRYSTAL STRUCTURE OF 2,3-DIHYDROXYBIPHENYL 1,2-DIOXYGENASE COMPLEXED WITH 3-METHYL CATECHOL UNDER ANAEROBIC CONDITION
分子名称:2,3-DIHYDROXYBIPHENYL 1,2-DIOXYGENASE, FE (II) ION, 3-METHYLCATECHOL, ...
著者Han, S., Bolin, J.T.
登録日2001-12-18
公開日2002-03-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Molecular basis for the stabilization and inhibition of 2, 3-dihydroxybiphenyl 1,2-dioxygenase by t-butanol.
J.Biol.Chem., 273, 1998
1QAM
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THE STRUCTURE OF THE RRNA METHYLTRANSFERASE ERMC': IMPLICATIONS FOR THE REACTION MECHANISM
分子名称:ERMC' METHYLTRANSFERASE, ACETATE ION
著者Schluckebier, G., Zhong, P., Stewart, K.D., Kavanaugh, T.J., Abad-Zapatero, C.
登録日1999-03-25
公開日2000-03-29
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The 2.2 A structure of the rRNA methyltransferase ErmC' and its complexes with cofactor and cofactor analogs: implications for the reaction mechanism.
J.Mol.Biol., 289, 1999
1QAN
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THE STRUCTURE OF THE RRNA METHYLTRANSFERASE ERMC': IMPLICATIONS FOR THE REACTION MECHANISM
分子名称:ERMC' METHYLTRANSFERASE, ACETATE ION, S-ADENOSYL-L-HOMOCYSTEINE
著者Schluckebier, G., Zhong, P., Stewart, K.D., Kavanaugh, T.J., Abad-Zapatero, C.
登録日1999-03-26
公開日2000-03-29
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The 2.2 A structure of the rRNA methyltransferase ErmC' and its complexes with cofactor and cofactor analogs: implications for the reaction mechanism.
J.Mol.Biol., 289, 1999
1QAO
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THE STRUCTURE OF THE RRNA METHYLTRANSFERASE ERMC': IMPLICATIONS FOR THE REACTION MECHANISM
分子名称:ERMC' METHYLTRANSFERASE, S-ADENOSYLMETHIONINE
著者Schluckebier, G., Zhong, P., Stewart, K.D., Kavanaugh, T.J., Abad-Zapatero, C.
登録日1999-03-26
公開日2000-03-29
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The 2.2 A structure of the rRNA methyltransferase ErmC' and its complexes with cofactor and cofactor analogs: implications for the reaction mechanism.
J.Mol.Biol., 289, 1999
1QAQ
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THE STRUCTURE OF THE RRNA METHYLTRANSFERASE ERMC': IMPLICATIONS FOR THE REACTION MECHANISM
分子名称:ERMC' RRNA METHYLTRANSFERASE, SINEFUNGIN
著者Schluckebier, G., Zhong, P., Stewart, K.D., Kavanaugh, T.J., Abad-Zapatero, C.
登録日1999-03-28
公開日2000-03-29
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The 2.2 A structure of the rRNA methyltransferase ErmC' and its complexes with cofactor and cofactor analogs: implications for the reaction mechanism.
J.Mol.Biol., 289, 1999