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4AVR
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CRYSTAL STRUCTURE OF THE HYPOTHETICAL PROTEIN PA4485 FROM PSEUDOMONAS AERUGINOSA
Descriptor:PA4485
Authors:McMahon, S.A., Moynie, L., Liu, H., Duthie, F., Alphey, M.S., Naismith, J.H.
Deposit date:2012-05-29
Release date:2013-01-09
Last modified:2013-01-23
Method:X-RAY DIFFRACTION (1.08 Å)
Cite:The Aeropath Project Targeting Pseudomonas Aeruginosa: Crystallographic Studies for Assessment of Potential Targets in Early-Stage Drug Discovery.
Acta Crystallogr.,Sect.F, 69, 2013
3ZTP
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ORTHORHOMBIC CRYSTAL FORM P21212 OF THE AQUIFEX AEOLICUS NUCLEOSIDE DIPHOSPHATE KINASE
Descriptor:NUCLEOSIDE DIPHOSPHATE KINASE, GLYCEROL, SULFATE ION
Authors:Boissier, F., Georgescauld, F., Moynie, L., Dupuy, J.-W., Sarger, C., Podar, M., Lascu, I., Giraud, M.-F., Dautant, A.
Deposit date:2011-07-12
Release date:2012-03-14
Last modified:2012-05-23
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:An Intersubunit Disulfide Bridge Stabilizes the Tetrameric Nucleoside Diphosphate Kinase of Aquifex Aeolicus.
Proteins, 80, 2012
4B9E
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STRUCTURE OF A PUTATIVE EPOXIDE HYDROLASE FROM PSEUDOMONAS AERUGINOSA, WITH BOUND MFA.
Descriptor:PROBABLE EPOXIDE HYDROLASE, fluoroacetic acid, SULFATE ION, ...
Authors:Schmidberger, J.W., Schnell, R., Schneider, G.
Deposit date:2012-09-04
Release date:2013-02-06
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The Aeropath Project Targeting Pseudomonas Aeruginosa: Crystallographic Studies for Assessment of Potential Targets in Early-Stage Drug Discovery.
Acta Crystallogr.,Sect.F, 69, 2013
4B9A
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STRUCTURE OF A PUTATIVE EPOXIDE HYDROLASE FROM PSEUDOMONAS AERUGINOSA.
Descriptor:PROBABLE EPOXIDE HYDROLASE, SULFATE ION, GLYCEROL
Authors:Schmidberger, J.W., Schnell, R., Schneider, G.
Deposit date:2012-09-03
Release date:2013-02-06
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:The Aeropath Project Targeting Pseudomonas Aeruginosa: Crystallographic Studies for Assessment of Potential Targets in Early-Stage Drug Discovery.
Acta Crystallogr.,Sect.F, 69, 2013
3ZTO
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ORTHORHOMBIC CRYSTAL FORM C222 OF THE AQUIFEX AEOLICUS NUCLEOSIDE DIPHOSPHATE KINASE
Descriptor:NUCLEOSIDE DIPHOSPHATE KINASE, SULFATE ION
Authors:Boissier, F., Georgescauld, F., Moynie, L., Dupuy, J.-W., Sarger, C., Podar, M., Lascu, I., Giraud, M.-F., Dautant, A.
Deposit date:2011-07-12
Release date:2012-03-14
Last modified:2012-05-23
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:An Intersubunit Disulfide Bridge Stabilizes the Tetrameric Nucleoside Diphosphate Kinase of Aquifex Aeolicus.
Proteins, 80, 2012
6GI2
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CRYSTAL STRUCTURE OF THE FERRIC ENTEROBACTIN ESTERASE (PFEE) MUTANT(S157A) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH TRIS-CATECHOL VECTOR
Descriptor:Ferric enterobactin esterase, FE (III) ION, ~{N}-[2-[[(2~{S})-2-[[2,3-bis(oxidanyl)phenyl]carbonylamino]-3-[[(2~{S})-2-[[2,3-bis(oxidanyl)phenyl]carbonylamino]-3-oxidanylidene-3-(prop-2-ynylamino)propyl]amino]-3-oxidanylidene-propyl]amino]-2-oxidanylidene-ethyl]-2,3-bis(oxidanyl)benzamide, ...
Authors:Moynie, L., Naismith, J.H.
Deposit date:2018-05-09
Release date:2018-06-20
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:A Key Role for the Periplasmic PfeE Esterase in Iron Acquisition via the Siderophore Enterobactin in Pseudomonas aeruginosa.
ACS Chem. Biol., 13, 2018
4BNW
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CRYSTAL STRUCTURE OF 3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (FABG) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH AN UNKNOWN LIGAND AT 1. 6A RESOLUTION
Descriptor:3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG, DI(HYDROXYETHYL)ETHER, TETRAETHYLENE GLYCOL, ...
Authors:Cukier, C.D., Schnell, R., Lindqvist, Y., Schneider, G.
Deposit date:2013-05-17
Release date:2013-09-18
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Discovery of an Allosteric Inhibitor Binding Site in 3-Oxo-Acyl-Acp Reductase from Pseudomonas Aeruginosa
Acs Chem.Biol., 8, 2013
2HUR
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ESCHERICHIA COLI NUCLEOSIDE DIPHOSPHATE KINASE
Descriptor:NUCLEOSIDE DIPHOSPHATE KINASE, SULFATE ION
Authors:Moynie, L., Giraud, M.-F., Georgescauld, F., Lascu, I., Dautant, A.
Deposit date:2006-07-27
Release date:2007-04-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:The structure of the Escherichia coli nucleoside diphosphate kinase reveals a new quaternary architecture for this enzyme family
Proteins, 67, 2007
6GI1
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CRYSTAL STRUCTURE OF THE FERRIC ENTEROBACTIN ESTERASE (PFEE) MUTANT(S157A) FROM PSEUDOMONAS AERUGINOSA IN PRESENCE OF ENTEROBACTIN
Descriptor:Ferric enterobactin esterase, FE (III) ION, 2-(2,3-DIHYDROXY-BENZOYLAMINO)-3-HYDROXY-PROPIONIC ACID, ...
Authors:Moynie, L., Naismith, J.H.
Deposit date:2018-05-09
Release date:2018-06-20
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:A Key Role for the Periplasmic PfeE Esterase in Iron Acquisition via the Siderophore Enterobactin in Pseudomonas aeruginosa.
ACS Chem. Biol., 13, 2018
2XBU
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SACCHAROMYCES CEREVISIAE HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH GMP (MONOCLINIC CRYSTAL FORM)
Descriptor:HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE, ACETATE ION, GUANOSINE-5'-MONOPHOSPHATE, ...
Authors:Moynie, L., Giraud, M.F., Breton, A., Boissier, F., Daignan-Fornier, B., Dautant, A.
Deposit date:2010-04-15
Release date:2011-05-04
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Functional Significance of Four Successive Glycine Residues in the Pyrophosphate Binding Loop of Fungal 6-Oxopurine Phosphoribosyltransferases.
Protein Sci., 21, 2012
4AG3
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CRYSTAL STRUCTURE OF 3-KETOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (FABG) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH NADPH AT 1.8A RESOLUTION
Descriptor:3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PENTAETHYLENE GLYCOL
Authors:Cukier, C.D., Schnell, R., Schneider, G., Lindqvist, Y.
Deposit date:2012-01-24
Release date:2013-02-06
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Discovery of an Allosteric Inhibitor Binding Site in 3-Oxo-Acyl-Acp Reductase from Pseudomonas Aeruginosa
Acs Chem.Biol., 8, 2013
4BNY
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CRYSTAL STRUCTURE OF 3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (FABG) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH 4-(2-PHENYLTHIENO(3,2-D) PYRIMIDIN-4-YL)MORPHOLINE AT 1.8A RESOLUTION
Descriptor:3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG, 4-(2-phenylthieno[3,2-d]pyrimidin-4-yl)morpholine
Authors:Cukier, C.D., Schnell, R., Lindqvist, Y., Schneider, G.
Deposit date:2013-05-17
Release date:2013-09-18
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Discovery of an Allosteric Inhibitor Binding Site in 3-Oxo-Acyl-Acp Reductase from Pseudomonas Aeruginosa
Acs Chem.Biol., 8, 2013
6HCP
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CRYSTAL STRUCTURE OF BAUA, THE FERRIC PREACINETOBACTIN RECEPTOR FROM ACINETOBACTER BAUMANNII
Descriptor:BauA, 1,2-ETHANEDIOL, (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, ...
Authors:Moynie, L., Naismith, J.H.
Deposit date:2018-08-16
Release date:2018-10-10
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Preacinetobactin not acinetobactin is essential for iron uptake by the BauA transporter of the pathogenAcinetobacter baumannii.
Elife, 7, 2018
4ANE
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R80N MUTANT OF NUCLEOSIDE DIPHOSPHATE KINASE FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:NUCLEOSIDE DIPHOSPHATE KINASE, CITRIC ACID
Authors:Georgescauld, F., Moynie, L., Habersetzer, J., Lascu, I., Dautant, A.
Deposit date:2012-03-16
Release date:2013-03-13
Last modified:2014-01-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of Mycobacterium Tuberculosis Nucleoside Diphosphate Kinase R80N Mutant in Complex with Citrate
Acta Crystallogr.,Sect.D, 70, 2014
4B0B
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CRYSTAL STRUCTURE OF 3-HYDROXYDECANOYL-ACYL CARRIER PROTEIN DEHYDRATASE (FABA) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH 3-(PYRIDIN-2-YLOXY)ANILINE
Descriptor:3-HYDROXYDECANOYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE, 3-(pyridin-2-yloxy)aniline
Authors:Moynie, L., McMahon, S.A., Duthie, F.G., Taylor, J.W., Naismith, J.H.
Deposit date:2012-07-01
Release date:2012-11-28
Last modified:2013-01-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Insights Into the Mechanism and Inhibition of the Beta-Hydroxydecanoyl-Acyl Carrier Protein Dehydratase from Pseudomonasaeruginosa.
J.Mol.Biol., 425, 2013
4BO2
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CRYSTAL STRUCTURE OF 3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (FABG) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH 1-(1-ETHYLBENZIMIDAZOL-2- YL)-3-(2-METHOXYPHENYL)UREA AT 1.9A RESOLUTION
Descriptor:3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG, 1-(1-ethylbenzimidazol-2-yl)-3-(2-methoxyphenyl)urea
Authors:Cukier, C.D., Schnell, R., Lindqvist, Y., Schneider, G.
Deposit date:2013-05-18
Release date:2013-09-18
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discovery of an Allosteric Inhibitor Binding Site in 3-Oxo-Acyl-Acp Reductase from Pseudomonas Aeruginosa
Acs Chem.Biol., 8, 2013
5FOK
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CRYSTAL STRUCTURE OF THE SIDEROPHORE RECEPTOR PIUA FROM PSEUDOMONAS AERUGINOSA
Descriptor:IRON TRANSPORT OUTER MEMBRANE RECEPTOR, (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, SODIUM ION, ...
Authors:Moynie, L., Naismith, J.H.
Deposit date:2015-11-23
Release date:2016-05-11
Last modified:2017-05-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure and Function of the PiuA and PirA Siderophore-Drug Receptors from Pseudomonas aeruginosa and Acinetobacter baumannii.
Antimicrob. Agents Chemother., 61, 2017
5FP1
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CRYSTAL STRUCTURE OF THE SIDEROPHORE RECEPTOR PIUA FROM ACINETOBACTER BAUMANNII
Descriptor:TONB-DEPENDENT SIDEROPHORE RECEPTOR, PHOSPHATE ION, (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE
Authors:Moynie, L., Tortajada, A., Naismith, J.H.
Deposit date:2015-11-26
Release date:2016-05-11
Last modified:2017-05-03
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Structure and Function of the PiuA and PirA Siderophore-Drug Receptors from Pseudomonas aeruginosa and Acinetobacter baumannii.
Antimicrob. Agents Chemother., 61, 2017
2XU8
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STRUCTURE OF PA1645
Descriptor:PA1645, SULFATE ION
Authors:Abdelli, W.B., Moynie, L., McMahon, S.A., Liu, H., Alphey, M.S., Naismith, J.H.
Deposit date:2010-10-15
Release date:2010-12-29
Last modified:2015-08-19
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:The Aeropath Project Targeting Pseudomonas Aeruginosa: Crystallographic Studies for Assessment of Potential Targets in Early-Stage Drug Discovery
Acta Crystallogr.,Sect.F, 69, 2013
4B79
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THE AEROPATH PROJECT AND PSEUDOMONAS AERUGINOSA HIGH-THROUGHPUT CRYSTALLOGRAPHIC STUDIES FOR ASSESSMENT OF POTENTIAL TARGETS IN EARLY STAGE DRUG DISCOVERY.
Descriptor:PROBABLE SHORT-CHAIN DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Moynie, L., McMahon, S.A., Alphey, M.S., Liu, H., Duthie, F., Naismith, J.H.
Deposit date:2012-08-16
Release date:2012-08-29
Last modified:2013-01-23
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:The Aeropath Project Targeting Pseudomonas Aeruginosa: Crystallographic Studies for Assessment of Potential Targets in Early-Stage Drug Discovery
Acta Crystallogr.,Sect.F, 69, 2013
4AVY
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THE AEROPATH PROJECT AND PSEUDOMONAS AERUGINOSA HIGH-THROUGHPUT CRYSTALLOGRAPHIC STUDIES FOR ASSESSMENT OF POTENTIAL TARGETS IN EARLY STAGE DRUG DISCOVERY.
Descriptor:PROBABLE SHORT-CHAIN DEHYDROGENASE
Authors:Moynie, L., McMahon, S.A., Alphey, M.S., Liu, H., Duthie, F., Naismith, J.H.
Deposit date:2012-05-30
Release date:2012-12-12
Last modified:2013-01-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Aeropath Project Targeting Pseudomonas Aeruginosa: Crystallographic Studies for Assessment of Potential Targets in Early-Stage Drug Discovery
Acta Crystallogr.,Sect.F, 69, 2013
4BNU
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CRYSTAL STRUCTURE OF 3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (FABG) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH 2-PHENYL-4-(1,2,4- TRIAZOL-4-YL)QUINAZOLINE AT 2.0A RESOLUTION
Descriptor:3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG, 2-phenyl-4-(1,2,4-triazol-4-yl)quinazoline
Authors:Cukier, C.D., Schnell, R., Lindqvist, Y., Schneider, G.
Deposit date:2013-05-17
Release date:2013-09-18
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Discovery of an Allosteric Inhibitor Binding Site in 3-Oxo-Acyl-Acp Reductase from Pseudomonas Aeruginosa
Acs Chem.Biol., 8, 2013
6GI0
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CRYSTAL STRUCTURE OF THE FERRIC ENTEROBACTIN ESTERASE (PFEE) FROM PSEUDOMONAS AERUGINOSA
Descriptor:Ferric enterobactin esterase, NITRATE ION
Authors:Moynie, L., Naismith, J.H.
Deposit date:2018-05-09
Release date:2018-06-20
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:A Key Role for the Periplasmic PfeE Esterase in Iron Acquisition via the Siderophore Enterobactin in Pseudomonas aeruginosa.
ACS Chem. Biol., 13, 2018
4FQ9
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CRYSTAL STRUCTURE OF 3-HYDROXYDECANOYL-ACYL CARRIER PROTEIN DEHYDRATASE (FABA) FROM PSEUDOMONAS AERUGINOSA
Descriptor:3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, PHOSPHATE ION, GLYCEROL
Authors:Moynie, L., Mcmahon, S.A., Duthie, F.G., Naismith, J.H.
Deposit date:2012-06-25
Release date:2013-03-27
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Structural insights into the mechanism and inhibition of the beta-hydroxydecanoyl-acyl carrier protein dehydratase from Pseudomonas aeruginosa
J.Mol.Biol., 425, 2013
4B0I
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CRYSTAL STRUCTURE OF 3-HYDROXYDECANOYL-ACYL CARRIER PROTEIN DEHYDRATASE (FABA) MUTANT (H70N) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH 3-HYDROXYDECANOYL-N-ACETYL CYSTEAMINE
Descriptor:3-HYDROXYDECANOYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE, S-[2-(acetylamino)ethyl] (3R)-3-hydroxydecanethioate
Authors:Moynie, L., McMahon, S.A., Leckie, S.M., Duthie, F.G., Koehnke, A., Naismith, J.H.
Deposit date:2012-07-02
Release date:2012-11-28
Last modified:2013-01-16
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structural Insights Into the Mechanism and Inhibition of the Beta-Hydroxydecanoyl-Acyl Carrier Protein Dehydratase from Pseudomonas Aeruginosa
J.Mol.Biol., 425, 2013