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2MB0
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BU of 2mb0 by Molmil
Solution structure of hnRNP G RRM in complex with the RNA 5'-AUCAAA-3'
Descriptor: RNA-binding motif protein, X chromosome, RNA_(5'-R(*AP*UP*CP*AP*AP*A)-3')
Authors:Moursy, A, Allain, F.H.-T, Clery, A.
Deposit date:2013-07-22
Release date:2014-04-09
Last modified:2014-06-25
Method:SOLUTION NMR
Cite:Characterization of the RNA recognition mode of hnRNP G extends its role in SMN2 splicing regulation.
Nucleic Acids Res., 42, 2014
7QDD
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BU of 7qdd by Molmil
NMR structure of Npl3 RRM1 bound to the AUCCAA RNA
Descriptor: Nucleolar protein 3, RNA (5'-R(*AP*UP*CP*CP*AP*A)-3')
Authors:Clery, A, Allain, F.H.-T, Moursy, A.
Deposit date:2021-11-26
Release date:2022-10-26
Last modified:2024-01-10
Method:SOLUTION NMR
Cite:RNA recognition by Npl3p reveals U2 snRNA-binding compatible with a chaperone role during splicing.
Nat Commun, 14, 2023
7QDE
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BU of 7qde by Molmil
NMR structure of Npl3 RRM12 bound to the AUCCAGUGGAA RNA
Descriptor: Nucleolar protein 3, RNA (5'-R(*AP*UP*CP*CP*AP*GP*UP*GP*GP*AP*A)-3')
Authors:Allain, F.H.-T, Clery, A, Moursy, A.
Deposit date:2021-11-26
Release date:2022-12-21
Last modified:2024-01-10
Method:SOLUTION NMR
Cite:RNA recognition by Npl3p reveals U2 snRNA-binding compatible with a chaperone role during splicing.
Nat Commun, 14, 2023
2M8D
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BU of 2m8d by Molmil
Structure of SRSF1 RRM2 in complex with the RNA 5'-UGAAGGAC-3'
Descriptor: RNA (5'-R(*UP*GP*AP*AP*GP*GP*AP*C)-3'), Serine/arginine-rich splicing factor 1
Authors:Clery, A, Sinha, R, Anczukow, O, Corrionero, A, Moursy, A, Daubner, G, Valcarcel, J, Krainer, A.R, Allain, F.H.T.
Deposit date:2013-05-17
Release date:2013-07-10
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Isolated pseudo-RNA-recognition motifs of SR proteins can regulate splicing using a noncanonical mode of RNA recognition.
Proc.Natl.Acad.Sci.USA, 110, 2013
6HMO
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BU of 6hmo by Molmil
Solution structure of the RNA duplex formed by the 5'-end of U1snRNA and the 5'-splice site of SMN2 exon7 in complex with the SMN-C5 splicing modifier
Descriptor: 2-(8-fluoranyl-2-methyl-imidazo[1,2-a]pyridin-6-yl)-7-(4-methylpiperazin-1-yl)pyrido[1,2-a]pyrimidin-4-one, RNA (5'-R(*AP*UP*AP*CP*(PSU)P*(PSU)P*AP*CP*CP*UP*G)-3'), RNA (5'-R(*GP*GP*AP*GP*UP*AP*AP*GP*UP*CP*U)-3')
Authors:Campagne, S, Allain, F.H.
Deposit date:2018-09-12
Release date:2019-08-14
Last modified:2020-02-26
Method:SOLUTION NMR
Cite:Structural basis of a small molecule targeting RNA for a specific splicing correction.
Nat.Chem.Biol., 15, 2019
6HMI
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BU of 6hmi by Molmil
Solution structure of the RNA duplex formed by the 5'-end of U1snRNA and the 5'-splice site of SMN2 exon7
Descriptor: RNA (5'-R(*AP*UP*AP*CP*(PSU)P*(PSU)P*AP*CP*CP*UP*G)-3'), RNA (5'-R(*GP*GP*AP*GP*UP*AP*AP*GP*UP*CP*U)-3')
Authors:Campagne, S, Allain, F.H.
Deposit date:2018-09-12
Release date:2019-08-14
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural basis of a small molecule targeting RNA for a specific splicing correction.
Nat.Chem.Biol., 15, 2019
6HPJ
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BU of 6hpj by Molmil
Structure of human SRSF1 RRM1 bound to AACAAA RNA
Descriptor: Immunoglobulin G-binding protein G,Serine/arginine-rich splicing factor 1, RNA (5'-R(*AP*AP*CP*AP*AP*A)-3')
Authors:Allain, F.T.H, Clery, A.
Deposit date:2018-09-21
Release date:2020-11-18
Last modified:2021-06-02
Method:SOLUTION NMR
Cite:Structure of SRSF1 RRM1 bound to RNA reveals an unexpected bimodal mode of interaction and explains its involvement in SMN1 exon7 splicing.
Nat Commun, 12, 2021
5OR0
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BU of 5or0 by Molmil
NMR derived model of the 5'-splice site of SMN2 in complex with the 5'-end of U1 snRNA
Descriptor: RNA (5'-R(P*AP*UP*AP*CP*(PSU)P*(PSU)P*AP*CP*CP*UP*G)-3'), RNA (5'-R(P*GP*GP*AP*GP*UP*AP*AP*GP*UP*CP*U)-3')
Authors:Campagne, S, Clery, A, Allain, F.H.
Deposit date:2017-08-14
Release date:2017-08-30
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Binding to SMN2 pre-mRNA-protein complex elicits specificity for small molecule splicing modifiers.
Nat Commun, 8, 2017
5MPG
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BU of 5mpg by Molmil
Solution NMR structure of hnRNP A1 RRM1 in complex with 5'-UUAGGUC-3' RNA
Descriptor: Heterogeneous nuclear ribonucleoprotein A1, RNA UUAGGUC
Authors:Barraud, P, Allain, F.H.-T.
Deposit date:2016-12-16
Release date:2017-07-05
Last modified:2019-05-08
Method:SOLUTION NMR
Cite:Tandem hnRNP A1 RNA recognition motifs act in concert to repress the splicing of survival motor neuron exon 7.
Elife, 6, 2017
5MPL
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BU of 5mpl by Molmil
hnRNP A1 RRM2 in complex with 5'-UCAGUU-3' RNA
Descriptor: Heterogeneous nuclear ribonucleoprotein A1, RNA UCAGUU
Authors:Barraud, P, Allain, F.H.-T.
Deposit date:2016-12-16
Release date:2017-07-05
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Tandem hnRNP A1 RNA recognition motifs act in concert to repress the splicing of survival motor neuron exon 7.
Elife, 6, 2017

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