3C0W
 
 | | I-SceI in complex with a bottom nicked DNA substrate | | Descriptor: | CALCIUM ION, DNA (5'-D(*DAP*DCP*DGP*DCP*DTP*DAP*DGP*DGP*DGP*DAP*DTP*DAP*DAP*DCP*DAP*DGP*DGP*DGP*DTP*DAP*DAP*DTP*DAP*DC)-3'), DNA (5'-D(*DGP*DTP*DAP*DTP*DTP*DAP*DCP*DCP*DCP*DTP*DGP*DTP*DTP*DAP*DT)-3'), ... | | Authors: | Moure, C.M, Gimble, F.S, Quiocho, F.A. | | Deposit date: | 2008-01-21 | | Release date: | 2008-05-06 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structures of I-SceI complexed to nicked DNA substrates: snapshots of intermediates along the DNA cleavage reaction pathway.
Nucleic Acids Res., 36, 2008
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3C0X
 | | I-SceI in complex with a top nicked DNA substrate | | Descriptor: | CALCIUM ION, DNA (5'-D(*DC*DAP*DCP*DGP*DCP*DTP*DAP*DGP*DGP*DGP*DAP*DTP*DAP*DA)-3'), DNA (5'-D(*DG*DGP*DTP*DAP*DTP*DTP*DAP*DCP*DCP*DCP*DTP*DGP*DTP*DTP*DAP*DTP*DCP*DCP*DCP*DTP*DAP*DGP*DCP*DGP*DT)-3'), ... | | Authors: | Moure, C.M, Gimble, F.S, Quiocho, F.A. | | Deposit date: | 2008-01-21 | | Release date: | 2008-05-06 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structures of I-SceI complexed to nicked DNA substrates: snapshots of intermediates along the DNA cleavage reaction pathway.
Nucleic Acids Res., 36, 2008
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2GA9
 | | Crystal Structure of the Heterodimeric Vaccinia Virus Polyadenylate Polymerase with Bound ATP-gamma-S | | Descriptor: | CALCIUM ION, Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | Authors: | Moure, C.M, Bowman, B.R, Gershon, P.D, Quiocho, F.A. | | Deposit date: | 2006-03-08 | | Release date: | 2006-05-16 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structures of the vaccinia virus polyadenylate polymerase heterodimer: insights into ATP selectivity and processivity.
Mol.Cell, 22, 2006
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2GAF
 | | Crystal Structure of the Vaccinia Polyadenylate Polymerase Heterodimer (apo form) | | Descriptor: | Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase, Poly(A) polymerase catalytic subunit | | Authors: | Moure, C.M, Bowman, B.R, Gershon, P.D, Quiocho, F.A. | | Deposit date: | 2006-03-08 | | Release date: | 2006-05-16 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structures of the vaccinia virus polyadenylate polymerase heterodimer: insights into ATP selectivity and processivity.
Mol.Cell, 22, 2006
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1LWS
 | | Crystal structure of the intein homing endonuclease PI-SceI bound to its recognition sequence | | Descriptor: | CALCIUM ION, ENDONUCLEASE PI-SCEI, PI-SceI DNA recognition region bottom strand, ... | | Authors: | Moure, C.M, Gimble, F.S, Quiocho, F.A. | | Deposit date: | 2002-06-03 | | Release date: | 2002-09-27 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Crystal structure of the intein homing endonuclease PI-SceI bound to its recognition sequence.
Nat.Struct.Biol., 9, 2002
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1LWT
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1R7M
 | | The homing endonuclease I-SceI bound to its DNA recognition region | | Descriptor: | 5'-D(*CP*AP*CP*GP*CP*TP*AP*GP*GP*GP*AP*TP*AP*AP*CP*AP*GP*GP*GP*TP*AP*AP*TP*AP*C)-3', 5'-D(*GP*GP*TP*AP*TP*TP*AP*CP*CP*CP*TP*GP*TP*TP*AP*TP*CP*CP*CP*TP*AP*GP*CP*GP*T)-3', CALCIUM ION, ... | | Authors: | Moure, C.M, Gimble, F.S, Quiocho, F.A. | | Deposit date: | 2003-10-21 | | Release date: | 2004-10-26 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | The crystal structure of the gene targeting homing endonuclease I-SceI reveals the origins of its target site specificity
J.Mol.Biol., 334, 2003
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1G9V
 | | HIGH RESOLUTION CRYSTAL STRUCTURE OF DEOXY HEMOGLOBIN COMPLEXED WITH A POTENT ALLOSTERIC EFFECTOR | | Descriptor: | 2-{4-[(3,5-DIMETHYLANILINO)-CARBONYL-METHYL]-PHENOXY}-2-METHYLPROPIONIC ACID, HEMOGLOBIN ALPHA CHAIN, HEMOGLOBIN BETA CHAIN, ... | | Authors: | Safo, M.K, Moure, C.M, Burnett, J.C, Joshi, G.S, Abraham, D.J. | | Deposit date: | 2000-11-28 | | Release date: | 2000-12-06 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | High-resolution crystal structure of deoxy hemoglobin complexed with a potent allosteric effector.
Protein Sci., 10, 2001
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1K0Y
 | | X-ray Crystallographic Analyses of Symmetrical Allosteric Effectors of Hemoglobin. Compounds Designed to Link Primary and Secondary Binding Sites | | Descriptor: | 2-{4-[(3{2-[4-(1-CARBOXY-1-METHYL-ETHOXY)-PHENYL]-ACETYLAMINO}-PHENYLCARBAMOYL)-METHYL]-PHENOXY}-2-METHYL-PROPIONIC ACID, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ... | | Authors: | Safo, M.K, Boyiri, T, Burnett, J.C, Danso-Danquah, R, Moure, C.M, Joshi, G.S, Abraham, D.J. | | Deposit date: | 2001-09-21 | | Release date: | 2001-10-03 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.87 Å) | | Cite: | X-ray crystallographic analyses of symmetrical allosteric effectors of hemoglobin: compounds designed to link primary and secondary binding sites.
Acta Crystallogr.,Sect.D, 58, 2002
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2AQL
 | | Crystal Structure of the MRG15 MRG domain | | Descriptor: | Mortality factor 4-like protein 1 | | Authors: | Quiocho, F.A, Bowman, B.R. | | Deposit date: | 2005-08-18 | | Release date: | 2006-02-28 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Multipurpose MRG domain involved in cell senescence and proliferation exhibits structural homology to a DNA-interacting domain.
Structure, 14, 2006
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3OWG
 | | Crystal structure of vaccinia virus Polyadenylate polymerase(vp55) | | Descriptor: | Poly(A) polymerase catalytic subunit | | Authors: | Li, C, Li, H, Zhou, S, Gershon, P.D, Poulos, T.L. | | Deposit date: | 2010-09-17 | | Release date: | 2011-09-21 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.86 Å) | | Cite: | Domain-level rocking motion within a polymerase that translocates on single-stranded nucleic acid.
Acta Crystallogr.,Sect.D, 69, 2013
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3ERC
 | | Crystal structure of the heterodimeric vaccinia virus mRNA polyadenylate polymerase with three fragments of RNA and 3'-deoxy ATP | | Descriptor: | 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase, ... | | Authors: | Li, C, Li, H, Zhou, S, Poulos, T.L, Gershon, P.D. | | Deposit date: | 2008-10-01 | | Release date: | 2009-06-16 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (3.21 Å) | | Cite: | Polymerase Translocation with Respect to Single-Stranded Nucleic Acid: Looping or Wrapping of Primer around a Poly(A) Polymerase
Structure, 17, 2009
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3ER8
 | | Crystal structure of the heterodimeric vaccinia virus mRNA polyadenylate polymerase complex with two fragments of RNA | | Descriptor: | Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase, Poly(A) polymerase catalytic subunit, RNA/DNA chimera 5'-D(CP*CP*)R(UP*UP*)D(C)-3', ... | | Authors: | Li, C, Li, H, Zhou, S, Poulos, T.L, Gershon, P.D. | | Deposit date: | 2008-10-01 | | Release date: | 2009-06-16 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (3.18 Å) | | Cite: | Polymerase Translocation with Respect to Single-Stranded Nucleic Acid: Looping or Wrapping of Primer around a Poly(A) Polymerase
Structure, 17, 2009
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3ER9
 | | Crystal structure of the heterodimeric vaccinia virus mRNA polyadenylate polymerase complex with UU and 3'-deoxy ATP | | Descriptor: | 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, 5'-R(UP*U)-3', CALCIUM ION, ... | | Authors: | Li, C, Li, H, Zhou, S, Poulos, T.L, Gershon, P.D. | | Deposit date: | 2008-10-01 | | Release date: | 2009-06-16 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.06 Å) | | Cite: | Polymerase Translocation with Respect to Single-Stranded Nucleic Acid: Looping or Wrapping of Primer around a Poly(A) Polymerase
Structure, 17, 2009
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