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8ORD
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BU of 8ord by Molmil
Cryo-EM map of zebrafish cardiac F-actin
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha 1b, ...
Authors:Bradshaw, M, Squire, J.M, Morris, E, Atkinson, G, Richardson, B, Lees, J, Paul, D.M.
Deposit date:2023-04-13
Release date:2023-08-02
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Zebrafish as a model for cardiac disease; Cryo-EM structure of native cardiac thin filaments from Danio Rerio.
J.Muscle Res.Cell.Motil., 44, 2023
6GL8
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BU of 6gl8 by Molmil
Crystal structure of Bcl-2 in complex with the novel orally active inhibitor S55746
Descriptor: Apoptosis regulator Bcl-2,Apoptosis regulator Bcl-2,Apoptosis regulator Bcl-2,Bcl-2-like protein 1,Apoptosis regulator Bcl-2,Apoptosis regulator Bcl-2,Apoptosis regulator Bcl-2, ~{N}-(4-hydroxyphenyl)-3-[6-[[(3~{S})-3-(morpholin-4-ylmethyl)-3,4-dihydro-1~{H}-isoquinolin-2-yl]carbonyl]-1,3-benzodioxol-5-yl]-~{N}-phenyl-5,6,7,8-tetrahydroindolizine-1-carboxamide
Authors:Casara, P, Davidson, J, Claperon, A, Le Toumelin-Braizat, G, Vogler, M, Bruno, A, Chanrion, M, Lysiak-Auvity, G, Le Diguarher, T, Starck, J.B, Chen, I, Whitehead, N, Graham, C, Matassova, N, Dokurno, P, Pedder, C, Wang, Y, Qiu, S, Girard, A.M, Schneider, E, Grave, F, Studeny, A, Guasconi, G, Rocchetti, F, Maiga, S, Henlin, J.M, Colland, F, Kraus-Berthier, L, Le Gouill, S, Dyer, M.J.S, Hubbard, R, Wood, M, Amiot, M, Cohen, G.M, Hickman, J.A, Morris, E, Murray, J, Geneste, O.
Deposit date:2018-05-23
Release date:2018-11-07
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:S55746 is a novel orally active BCL-2 selective and potent inhibitor that impairs hematological tumor growth.
Oncotarget, 9, 2018
7AST
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BU of 7ast by Molmil
Apo Human RNA Polymerase III
Descriptor: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ...
Authors:Ramsay, E.P, Abascal-Palacios, G, Daiss, J.L, King, H, Gouge, J, Pilsl, M, Beuron, F, Morris, E, Gunkel, P, Engel, C, Vannini, A.
Deposit date:2020-10-28
Release date:2020-12-23
Last modified:2020-12-30
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structure of human RNA polymerase III.
Nat Commun, 11, 2020
6EU3
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BU of 6eu3 by Molmil
Apo RNA Polymerase III - closed conformation (cPOL3)
Descriptor: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ...
Authors:Abascal-Palacios, G, Ramsay, E.P, Beuron, F, Morris, E, Vannini, A.
Deposit date:2017-10-27
Release date:2018-01-17
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis of RNA polymerase III transcription initiation.
Nature, 553, 2018
6EU1
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BU of 6eu1 by Molmil
RNA Polymerase III - open DNA complex (OC-POL3).
Descriptor: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ...
Authors:Abascal-Palacios, G, Ramsay, E.P, Beuron, F, Morris, E, Vannini, A.
Deposit date:2017-10-27
Release date:2018-01-17
Last modified:2020-11-18
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis of RNA polymerase III transcription initiation.
Nature, 553, 2018
6EU2
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BU of 6eu2 by Molmil
Apo RNA Polymerase III - open conformation (oPOL3)
Descriptor: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ...
Authors:Abascal-Palacios, G, Ramsay, E.P, Beuron, F, Morris, E, Vannini, A.
Deposit date:2017-10-27
Release date:2018-01-17
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis of RNA polymerase III transcription initiation.
Nature, 553, 2018
6EU0
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BU of 6eu0 by Molmil
RNA Polymerase III open pre-initiation complex (OC-PIC)
Descriptor: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ...
Authors:Abascal-Palacios, G, Ramsay, E.P, Beuron, F, Morris, E, Vannini, A.
Deposit date:2017-10-27
Release date:2018-01-17
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural basis of RNA polymerase III transcription initiation.
Nature, 553, 2018
6SO3
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BU of 6so3 by Molmil
The interacting head motif in insect flight muscle myosin thick filaments
Descriptor: Myosin 2 essential light chain striated muscle, Myosin 2 heavy chain striated muscle, Myosin 2 regulatory light chain striated muscle
Authors:Morris, E.P, Knupp, C, Squire, J.M.
Deposit date:2019-08-28
Release date:2020-07-08
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:The Interacting Head Motif Structure Does Not Explain the X-Ray Diffraction Patterns in Relaxed Vertebrate (Bony Fish) Skeletal Muscle and Insect (Lethocerus) Flight Muscle.
Biology (Basel), 8, 2019
3RBS
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BU of 3rbs by Molmil
Crystal structure of the myomesin domains 10 and 11
Descriptor: BETA-MERCAPTOETHANOL, Myomesin-1, NITRATE ION
Authors:Chatziefthimiou, S.D, Pinotsis, N, Wilmanns, M.
Deposit date:2011-03-29
Release date:2012-03-07
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Superhelical architecture of the Myosin filament-linking protein myomesin with unusual elastic properties.
Plos Biol., 10, 2012
2Y23
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BU of 2y23 by Molmil
CRYSTAL STRUCTURE OF THE MYOMESIN DOMAINS MY9-MY11
Descriptor: 2-(2-METHOXYETHOXY)ETHANOL, BETA-MERCAPTOETHANOL, MYOMESIN
Authors:Pinotsis, N, Chatziefthimiou, S.D, Wilmanns, M.
Deposit date:2010-12-13
Release date:2011-12-21
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Superhelical Architecture of the Myosin Filament-Linking Protein Myomesin with Unusual Elastic Properties.
Plos Biol., 10, 2012
2Y25
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BU of 2y25 by Molmil
Crystal structure of the myomesin domains My11-My13
Descriptor: MYOMESIN
Authors:Pinotsis, N, Chatziefthimiou, S.D, Wilmanns, M.
Deposit date:2010-12-13
Release date:2011-12-21
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Superhelical Architecture of the Myosin Filament-Linking Protein Myomesin with Unusual Elastic Properties.
Plos Biol., 10, 2012
5JU5
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BU of 5ju5 by Molmil
Crystal structure of the human Tankyrase 1 (TNKS) SAM domain (D1055R), crystal form 1
Descriptor: Tankyrase-1
Authors:Guetter, S, Mariotti, L, Cronin, N.
Deposit date:2016-05-10
Release date:2016-08-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Tankyrase Requires SAM Domain-Dependent Polymerization to Support Wnt-beta-Catenin Signaling.
Mol.Cell, 63, 2016
5JTI
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BU of 5jti by Molmil
Crystal structure of the human Tankyrase 1 (TNKS) SAM domain (D1055R), crystal form 2
Descriptor: Tankyrase-1
Authors:Guetter, S, Mariotti, L, Cronin, N.
Deposit date:2016-05-09
Release date:2016-08-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Tankyrase Requires SAM Domain-Dependent Polymerization to Support Wnt-beta-Catenin Signaling.
Mol.Cell, 63, 2016
7ASV
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BU of 7asv by Molmil
Crystal structure of tWHD2 of Rpc5 subunit of human RNA Polymerase III
Descriptor: ACETATE ION, DNA-directed RNA polymerase III subunit RPC5
Authors:Vannini, A, Abascal-Palacios, G, Ramsay, E.P.
Deposit date:2020-10-28
Release date:2020-12-30
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structure of human RNA polymerase III.
Nat Commun, 11, 2020
7ASU
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BU of 7asu by Molmil
Crystal structure of tWHD1 of Rpc5 subunit of human RNA Polymerase III
Descriptor: DNA-directed RNA polymerase III subunit RPC5, ZINC ION
Authors:Vannini, A, Abascal-Palacios, G, Ramsay, E.P.
Deposit date:2020-10-28
Release date:2020-12-30
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Structure of human RNA polymerase III.
Nat Commun, 11, 2020
5JRT
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BU of 5jrt by Molmil
Crystal structure of the human Tankyrase 2 (TNKS2) SAM domain (DH902/924RE)
Descriptor: Tankyrase-2
Authors:Guettler, S, Mariotti, L, Cronin, N.
Deposit date:2016-05-06
Release date:2016-08-03
Last modified:2016-08-17
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Tankyrase Requires SAM Domain-Dependent Polymerization to Support Wnt-beta-Catenin Signaling.
Mol.Cell, 63, 2016

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