Author results

6APJ
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CRYSTAL STRUCTURE OF HUMAN ST6GALNAC2
分子名称:Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2, N-ACETYL-D-GLUCOSAMINE
著者Forouhar, F., Moremen, K.W., Northeast Structural Genomics Consortium (NESG), Tong, L.
登録日2017-08-17
公開日2017-12-20
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Expression system for structural and functional studies of human glycosylation enzymes.
Nat. Chem. Biol., 14, 2018
6APL
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CRYSTAL STRUCTURE OF HUMAN ST6GALNAC2 IN COMPLEX WITH CMP
分子名称:Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2, CYTIDINE-5'-MONOPHOSPHATE, N-ACETYL-D-GLUCOSAMINE
著者Forouhar, F., Moremen, K.W., Northeast Structural Genomics Consortium (NESG), Tong, L.
登録日2017-08-17
公開日2017-12-20
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Expression system for structural and functional studies of human glycosylation enzymes.
Nat. Chem. Biol., 14, 2018
1FMI
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CRYSTAL STRUCTURE OF HUMAN CLASS I ALPHA1,2-MANNOSIDASE
分子名称:ENDOPLASMIC RETICULUM ALPHA-MANNOSIDASE I, CALCIUM ION, SULFATE ION
著者Vallee, F., Karaveg, K., Herscovics, A., Moremen, K.W., Howell, P.L.
登録日2000-08-17
公開日2001-01-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for catalysis and inhibition of N-glycan processing class I alpha 1,2-mannosidases.
J.Biol.Chem., 275, 2000
1FO2
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CRYSTAL STRUCTURE OF HUMAN CLASS I ALPHA1,2-MANNOSIDASE IN COMPLEX WITH 1-DEOXYMANNOJIRIMYCIN
分子名称:ALPHA1,2-MANNOSIDASE, CALCIUM ION, SULFATE ION, ...
著者Vallee, F., Karaveg, K., Moremen, K.W., Herscovics, A., Howell, P.L.
登録日2000-08-24
公開日2001-01-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Structural basis for catalysis and inhibition of N-glycan processing class I alpha 1,2-mannosidases.
J.Biol.Chem., 275, 2000
1FO3
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CRYSTAL STRUCTURE OF HUMAN CLASS I ALPHA1,2-MANNOSIDASE IN COMPLEX WITH KIFUNENSINE
分子名称:ALPHA1,2-MANNOSIDASE, CALCIUM ION, SULFATE ION, ...
著者Vallee, F., Karaveg, K., Moremen, K.W., Herscovics, A., Howell, P.L.
登録日2000-08-24
公開日2001-01-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural basis for catalysis and inhibition of N-glycan processing class I alpha 1,2-mannosidases.
J.Biol.Chem., 275, 2000
1NXC
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STRUCTURE OF MOUSE GOLGI ALPHA-1,2-MANNOSIDASE IA REVEALS THE MOLECULAR BASIS FOR SUBSTRATE SPECIFICITY AMONG CLASS I ENZYMES (FAMILY 47 GLYCOSIDASES)
分子名称:Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
著者Tempel, W., Liu, Z.-J., Karaveg, K., Rose, J., Moremen, K.W., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
登録日2003-02-10
公開日2004-05-04
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Structure of mouse Golgi alpha-mannosidase IA reveals the molecular basis for substrate specificity among class 1 (family 47 glycosylhydrolase) alpha1,2-mannosidases
J.Biol.Chem., 279, 2004
1X9D
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CRYSTAL STRUCTURE OF HUMAN CLASS I ALPHA-1,2-MANNOSIDASE IN COMPLEX WITH THIO-DISACCHARIDE SUBSTRATE ANALOGUE
分子名称:Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, CALCIUM ION, SULFATE ION, ...
著者Karaveg, K., Tempel, W., Liu, Z.J., Siriwardena, A., Moremen, K.W., Wang, B.C.
登録日2004-08-20
公開日2005-02-22
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献Mechanism of class 1 (glycosylhydrolase family 47) {alpha}-mannosidases involved in N-glycan processing and endoplasmic reticulum quality control.
J.Biol.Chem., 280, 2005
2WZS
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STRUCTURE OF THE FAMILY GH92 INVERTING MANNOSIDASE BT3990 FROM BACTEROIDES THETAIOTAOMICRON VPI-5482 IN COMPLEX WITH MANNOIMIDAZOLE
分子名称:PUTATIVE ALPHA-1,2-MANNOSIDASE, CALCIUM ION, (5R,6R,7S,8R)-5-(HYDROXYMETHYL)-5,6,7,8-TETRAHYDROIMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL, ...
著者Zhu, Y., Suits, M.D.L., Thompson, A., Chavan, S., Dinev, Z., Dumon, C., Smith, N., Moremen, K.W., Xiang, Y., Siriwardena, A., Williams, S.J., Gilbert, H.J., Davies, G.J.
登録日2009-12-02
公開日2009-12-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Mechanistic Insights Into a Ca2+-Dependent Family of A-Mannosidases in a Human Gut Symbiont.
Nat.Chem.Biol., 6, 2010
4MPS
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CRYSTAL STRUCTURE OF RAT BETA-GALACTOSIDE ALPHA-2,6-SIALYLTRANSFERASE 1 (ST6GAL1), NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET RNR367A
分子名称:Beta-galactoside alpha-2,6-sialyltransferase 1, N-ACETYL-D-GLUCOSAMINE
著者Forouhar, F., Meng, L., Milaninia, S., Seetharaman, J., Su, M., Kornhaber, G., Montelione, G.T., Hunt, J.F., Moremen, K.W., Tong, L., Northeast Structural Genomics Consortium (NESG)
登録日2013-09-13
公開日2013-09-25
最終更新日2013-12-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Enzymatic Basis for N-Glycan Sialylation: STRUCTURE OF RAT alpha 2,6-SIALYLTRANSFERASE (ST6GAL1) REVEALS CONSERVED AND UNIQUE FEATURES FOR GLYCAN SIALYLATION.
J.Biol.Chem., 288, 2013
5FBH
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CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF HUMAN CALCIUM SENSING RECEPTOR WITH BOUND GD3+
分子名称:Extracellular calcium-sensing receptor, GADOLINIUM ION, MAGNESIUM ION, ...
著者Zhang, T., Zhang, C., Miller, C.L., Zou, J., Moremen, K.W., Brown, E.M., Yang, J.J., Hu, J.
登録日2015-12-14
公開日2016-06-22
最終更新日2016-07-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for regulation of human calcium-sensing receptor by magnesium ions and an unexpected tryptophan derivative co-agonist.
Sci Adv, 2, 2016
5FBK
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CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF HUMAN CALCIUM SENSING RECEPTOR
分子名称:Extracellular calcium-sensing receptor, CYCLOMETHYLTRYPTOPHAN, N-ACETYL-D-GLUCOSAMINE, ...
著者Zhang, T., Zhang, C., Miller, C.L., Zou, J., Moremen, K.W., Brown, E.M., Yang, J.J., Hu, J.
登録日2015-12-14
公開日2016-06-22
最終更新日2016-07-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for regulation of human calcium-sensing receptor by magnesium ions and an unexpected tryptophan derivative co-agonist.
Sci Adv, 2, 2016
5KIJ
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CRYSTAL STRUCTURE OF THE CLASS I HUMAN ENDOPLASMIC RETICULUM 1,2-ALPHA-MANNOSIDASE AND MAN9GLCNAC2-PA COMPLEX
分子名称:Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, LANTHANUM (III) ION, SULFATE ION, ...
著者Karaveg, K., Xiang, Y., Moremen, K.W.
登録日2016-06-16
公開日2017-05-10
最終更新日2017-09-06
実験手法X-RAY DIFFRACTION (1.649 Å)
主引用文献Substrate recognition and catalysis by GH47 alpha-mannosidases involved in Asn-linked glycan maturation in the mammalian secretory pathway.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
5KK7
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CRYSTAL STRUCTURE OF THE CLASS I HUMAN ENDOPLASMIC RETICULUM 1,2-ALPHA-MANNOSIDASE T688A MUTANT AND THIO-DISACCHARIDE SUBSTRATE ANALOG COMPLEX
分子名称:Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, METHYL-2-S-(ALPHA-D-MANNOPYRANOSYL)-2-THIO-ALPHA-D-MANNOPYRANOSIDE, CALCIUM ION, ...
著者Karaveg, K., Xiang, Y., Moremen, K.W.
登録日2016-06-21
公開日2017-05-10
実験手法X-RAY DIFFRACTION (1.7324 Å)
主引用文献Substrate recognition and catalysis by GH47 alpha-mannosidases involved in Asn-linked glycan maturation in the mammalian secretory pathway.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
5KKB
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STRUCTURE OF MOUSE GOLGI ALPHA-1,2-MANNOSIDASE IA AND MAN9GLCNAC2-PA COMPLEX
分子名称:Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA, BETA-D-MANNOSE, ALPHA-D-MANNOSE, ...
著者Xiang, Y., Moremen, K.W.
登録日2016-06-21
公開日2016-12-07
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (1.774 Å)
主引用文献Substrate recognition and catalysis by GH47 alpha-mannosidases involved in Asn-linked glycan maturation in the mammalian secretory pathway.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
2WVX
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STRUCTURE OF THE FAMILY GH92 INVERTING MANNOSIDASE BT3990 FROM BACTEROIDES THETAIOTAOMICRON VPI-5482
分子名称:PUTATIVE ALPHA-1,2-MANNOSIDASE, CALCIUM ION, GLYCEROL
著者Suits, M.D.L., Zhu, Y., Thompson, A., Gilbert, H.J., Davies, G.J.
登録日2009-10-21
公開日2009-11-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mechanistic Insights Into a Ca2+-Dependent Family of A-Mannosidases in a Human Gut Symbiont.
Nat.Chem.Biol., 6, 2010
2WVY
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STRUCTURE OF THE FAMILY GH92 INVERTING MANNOSIDASE BT2199 FROM BACTEROIDES THETAIOTAOMICRON VPI-5482
分子名称:ALPHA-1,2-MANNOSIDASE
著者Suits, M.D.L., Zhu, Y., Thompson, A., Gilbert, H.J., Davies, G.J.
登録日2009-10-21
公開日2009-11-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Mechanistic Insights Into a Ca2+-Dependent Family of A-Mannosidases in a Human Gut Symbiont.
Nat.Chem.Biol., 6, 2010
2WVZ
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STRUCTURE OF THE FAMILY GH92 INVERTING MANNOSIDASE BT3990 FROM BACTEROIDES THETAIOTAOMICRON VPI-5482
分子名称:PUTATIVE ALPHA-1,2-MANNOSIDASE, CALCIUM ION, KIFUNENSINE, ...
著者Suits, M.D.L., Zhu, Y., Thompson, A., Gilbert, H.J., Davies, G.J.
登録日2009-10-21
公開日2009-12-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Mechanistic Insights Into a Ca2+-Dependent Family of A-Mannosidases in a Human Gut Symbiont.
Nat.Chem.Biol., 6, 2010
2WW0
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STRUCTURE OF THE FAMILY GH92 INVERTING MANNOSIDASE BT3990 FROM BACTEROIDES THETAIOTAOMICRON VPI-5482
分子名称:PUTATIVE ALPHA-1,2-MANNOSIDASE, CALCIUM ION, 1S-8AB-OCTAHYDRO-INDOLIZIDINE-1A,2A,8B-TRIOL, ...
著者Suits, M.D.L., Thompson, A., Zhu, Y., Gilbert, H.J., Davies, G.J.
登録日2009-10-21
公開日2009-12-29
最終更新日2013-05-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Mechanistic Insights Into a Ca2+-Dependent Family of A-Mannosidases in a Human Gut Symbiont.
Nat.Chem.Biol., 6, 2010
2WW1
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STRUCTURE OF THE FAMILY GH92 INVERTING MANNOSIDASE BT3990 FROM BACTEROIDES THETAIOTAOMICRON VPI-5482 IN COMPLEX WITH THIOMANNOBIOSIDE
分子名称:PUTATIVE ALPHA-1,2-MANNOSIDASE, METHYL-2-S-(ALPHA-D-MANNOPYRANOSYL)-2-THIO-ALPHA-D-MANNOPYRANOSIDE
著者Suits, M.D.L., Zhu, Y., Thompson, A., Gilbert, H.J., Davies, G.J.
登録日2009-10-21
公開日2009-12-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Mechanistic Insights Into a Ca2+-Dependent Family of A-Mannosidases in a Human Gut Symbiont.
Nat.Chem.Biol., 6, 2010
2WW2
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STRUCTURE OF THE FAMILY GH92 INVERTING MANNOSIDASE BT2199 FROM BACTEROIDES THETAIOTAOMICRON VPI-5482
分子名称:ALPHA-1,2-MANNOSIDASE, (4S)-2-METHYL-2,4-PENTANEDIOL, SODIUM ION, ...
著者Suits, M.D.L., Zhu, Y., Thompson, A., Gilbert, H.J., Davies, G.J.
登録日2009-10-21
公開日2009-12-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mechanistic Insights Into a Ca2+-Dependent Family of A-Mannosidases in a Human Gut Symbiont.
Nat.Chem.Biol., 6, 2010
2WW3
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STRUCTURE OF THE FAMILY GH92 INVERTING MANNOSIDASE BT3990 FROM BACTEROIDES THETAIOTAOMICRON VPI-5482 IN COMPLEX WITH THIOMANNOBIOSIDE
分子名称:PUTATIVE ALPHA-1,2-MANNOSIDASE, CALCIUM ION, METHYL-2-S-(ALPHA-D-MANNOPYRANOSYL)-2-THIO-ALPHA-D-MANNOPYRANOSIDE, ...
著者Suits, M.D.L., Zhu, Y., Thompson, A.J., Gilbert, H.J., Davies, G.J.
登録日2009-10-21
公開日2010-01-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Mechanistic Insights Into a Ca(2+)-Dependent Family of Alpha-Mannosidases in a Human Gut Symbiont.
Nat.Chem.Biol., 6, 2010
3BUB
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GOLGI ALPHA-MANNOSIDASE II WITH AN EMPTY ACTIVE SITE
分子名称:Alpha-mannosidase 2, N-ACETYL-D-GLUCOSAMINE, ZINC ION, ...
著者Kuntz, D.A., Rose, D.R.
登録日2008-01-02
公開日2008-07-01
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献Probing the substrate specificity of Golgi alpha-mannosidase II by use of synthetic oligosaccharides and a catalytic nucleophile mutant.
J.Am.Chem.Soc., 130, 2008
3BUD
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GOLGI MANNOSIDASE II D204A CATALYTIC NUCLEOPHILE MUTANT WITH AN EMPTY ACTIVE SITE
分子名称:Alpha-mannosidase 2, N-ACETYL-D-GLUCOSAMINE, PHOSPHATE ION, ...
著者Kuntz, D.A., Rose, D.R.
登録日2008-01-02
公開日2008-07-01
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Probing the substrate specificity of Golgi alpha-mannosidase II by use of synthetic oligosaccharides and a catalytic nucleophile mutant.
J.Am.Chem.Soc., 130, 2008
3BUI
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GOLGI MANNOSIDASE II D204A CATALYTIC NUCLEOPHILE MUTANT COMPLEX WITH TRIS
分子名称:Alpha-mannosidase 2, ZINC ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
著者Kuntz, D.A., Rose, D.R.
登録日2008-01-02
公開日2008-07-01
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Probing the substrate specificity of Golgi alpha-mannosidase II by use of synthetic oligosaccharides and a catalytic nucleophile mutant.
J.Am.Chem.Soc., 130, 2008
3BUP
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GOLGI ALPHA-MANNOSIDASE II D341N ACID-BASE CATALYST MUTANT WITH BOUND MANNOSE
分子名称:Alpha-mannosidase 2, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
著者Kuntz, D.A., Rose, D.R.
登録日2008-01-03
公開日2008-07-01
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Probing the substrate specificity of Golgi alpha-mannosidase II by use of synthetic oligosaccharides and a catalytic nucleophile mutant.
J.Am.Chem.Soc., 130, 2008
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