Author results

1GPD
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STUDIES OF ASYMMETRY IN THE THREE-DIMENSIONAL STRUCTURE OF LOBSTER D-GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE
Descriptor:D-GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHATE ION
Authors:Moras, D., Olsen, K.W., Sabesan, M.N., Buehner, M., Ford, G.C., Rossmann, M.G.
Deposit date:1975-07-01
Release date:1977-02-17
Last modified:2014-10-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Studies of asymmetry in the three-dimensional structure of lobster D-glyceraldehyde-3-phosphate dehydrogenase.
J.Biol.Chem., 250, 1975
3IXP
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CRYSTAL STRUCTURE OF THE ECDYSONE RECEPTOR BOUND TO BYI08346
Descriptor:Gene regulation protein, Ecdysone receptor, L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINE, ...
Authors:Moras, D., Billas, I.M.L., Browning, C.
Deposit date:2009-09-04
Release date:2010-12-15
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Adaptability of the ecdysone receptor bound to synthetic ligands
To be Published
1AH4
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PIG ALDOSE REDUCTASE, HOLO FORM
Descriptor:ALDOSE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Moras, D., Podjarny, A.
Deposit date:1997-04-12
Release date:1998-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:A 'specificity' pocket inferred from the crystal structures of the complexes of aldose reductase with the pharmaceutically important inhibitors tolrestat and sorbinil.
Structure, 5, 1997
1AH0
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PIG ALDOSE REDUCTASE COMPLEXED WITH SORBINIL
Descriptor:ALDOSE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SORBINIL
Authors:Moras, D., Podjarny, A.D.
Deposit date:1997-04-11
Release date:1998-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A 'specificity' pocket inferred from the crystal structures of the complexes of aldose reductase with the pharmaceutically important inhibitors tolrestat and sorbinil.
Structure, 5, 1997
1AH3
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ALDOSE REDUCTASE COMPLEXED WITH TOLRESTAT INHIBITOR
Descriptor:ALDOSE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TOLRESTAT
Authors:Moras, D., Podjarny, A.
Deposit date:1997-04-12
Release date:1998-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A 'specificity' pocket inferred from the crystal structures of the complexes of aldose reductase with the pharmaceutically important inhibitors tolrestat and sorbinil.
Structure, 5, 1997
1TXI
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CRYSTAL STRUCTURE OF THE VDR LIGAND BINDING DOMAIN COMPLEXED TO TX522
Descriptor:Vitamin D receptor, (1R,3R)-5-((Z)-2-((1R,7AS)-HEXAHYDRO-1-((S)-6-HYDROXY-6-METHYLHEPT-4-YN-2-YL)-7A-METHYL-1H-INDEN-4(7AH)-YLIDENE)ETHYLIDENE)CYCLOHEXANE-1,3-DIOL
Authors:Moras, D., Rochel, N.
Deposit date:2004-07-05
Release date:2005-05-10
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Superagonistic Action of 14-epi-Analogs of 1,25-Dihydroxyvitamin D Explained by Vitamin D Receptor-Coactivator Interaction
Mol.Pharmacol., 67, 2005
2R40
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CRYSTAL STRUCTURE OF 20E BOUND ECR/USP
Descriptor:Ecdysone Receptor, Ultraspiracle, CITRATE ANION, ...
Authors:Moras, D., Billas, I.M.L., Browning, C.
Deposit date:2007-08-30
Release date:2007-10-02
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.402 Å)
Cite:Critical Role of Desolvation in the Binding of 20-Hydroxyecdysone to the Ecdysone Receptor
J.Biol.Chem., 282, 2007
3D24
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CRYSTAL STRUCTURE OF LIGAND-BINDING DOMAIN OF ESTROGEN-RELATED RECEPTOR ALPHA (ERRALPHA) IN COMPLEX WITH THE PEROXISOME PROLIFERATORS-ACTIVATED RECEPTOR COACTIVATOR-1ALPHA BOX3 PEPTIDE (PGC-1ALPHA)
Descriptor:Steroid hormone receptor ERR1, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha
Authors:Moras, D., Greschik, H., Flaig, R., Sato, Y., Rochel, N., Structural Proteomics in Europe (SPINE)
Deposit date:2008-05-07
Release date:2008-06-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Communication between the ERR{alpha} Homodimer Interface and the PGC-1{alpha} Binding Surface via the Helix 8-9 Loop.
J.Biol.Chem., 283, 2008
2TRA
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RESTRAINED REFINEMENT OF TWO CRYSTALLINE FORMS OF YEAST ASPARTIC ACID AND PHENYLALANINE TRANSFER RNA CRYSTALS
Descriptor:TRNAASP, SPERMINE, MAGNESIUM ION
Authors:Westhof, E., Dumas, P., Moras, D.
Deposit date:1987-11-06
Release date:1987-11-06
Last modified:2016-06-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:Restrained refinement of two crystalline forms of yeast aspartic acid and phenylalanine transfer RNA crystals.
Acta Crystallogr.,Sect.A, 44, 1988
3TRA
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RESTRAINED REFINEMENT OF TWO CRYSTALLINE FORMS OF YEAST ASPARTIC ACID AND PHENYLALANINE TRANSFER RNA CRYSTALS
Descriptor:TRNAASP, MAGNESIUM ION
Authors:Westhof, E., Dumas, P., Moras, D.
Deposit date:1987-11-06
Release date:1987-11-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Restrained refinement of two crystalline forms of yeast aspartic acid and phenylalanine transfer RNA crystals.
Acta Crystallogr.,Sect.A, 44, 1988
1VTQ
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THREE-DIMENSIONAL STRUCTURE OF YEAST T-RNA-ASP. I. STRUCTURE DETERMINATION
Descriptor:T-RNA-ASP
Authors:Comarmond, M.B., Giege, R., Thierry, J.C., Moras, D., Fischer, J.
Deposit date:1985-06-11
Release date:2011-07-13
Last modified:2018-05-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:Three-Dimensional Structure of Yeast T-RNA-ASP. I. Structure Determination
Acta Crystallogr.,Sect.B, 42, 1986
1EOV
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FREE ASPARTYL-TRNA SYNTHETASE (ASPRS) (E.C. 6.1.1.12) FROM YEAST
Descriptor:ASPARTYL-TRNA SYNTHETASE
Authors:Sauter, C., Lorber, B., Cavarelli, J., Moras, D., Giege, R.
Deposit date:2000-03-24
Release date:2000-09-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The free yeast aspartyl-tRNA synthetase differs from the tRNA(Asp)-complexed enzyme by structural changes in the catalytic site, hinge region, and anticodon-binding domain.
J.Mol.Biol., 299, 2000
1ASY
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CLASS II AMINOACYL TRANSFER RNA SYNTHETASES: CRYSTAL STRUCTURE OF YEAST ASPARTYL-TRNA SYNTHETASE COMPLEXED WITH TRNA ASP
Descriptor:T-RNA (75-MER), ASPARTYL-tRNA SYNTHETASE
Authors:Ruff, M., Cavarelli, J., Rees, B., Krishnaswamy, S., Thierry, J.C., Moras, D.
Deposit date:1995-01-19
Release date:1995-05-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Class II aminoacyl transfer RNA synthetases: crystal structure of yeast aspartyl-tRNA synthetase complexed with tRNA(Asp).
Science, 252, 1991
1ASZ
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THE ACTIVE SITE OF YEAST ASPARTYL-TRNA SYNTHETASE: STRUCTURAL AND FUNCTIONAL ASPECTS OF THE AMINOACYLATION REACTION
Descriptor:T-RNA (75-MER), ASPARTYL-tRNA SYNTHETASE, ADENOSINE-5'-TRIPHOSPHATE
Authors:Cavarelli, J., Rees, B., Thierry, J.C., Moras, D.
Deposit date:1995-01-19
Release date:1995-05-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The active site of yeast aspartyl-tRNA synthetase: structural and functional aspects of the aminoacylation reaction.
EMBO J., 13, 1994
1ATT
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CRYSTAL STRUCTURE OF CLEAVED BOVINE ANTITHROMBIN III AT 3.2 ANGSTROMS RESOLUTION
Descriptor:ANTITHROMBIN III
Authors:Mourey, L., Samama, J.P., Delarue, M., Moras, D.
Deposit date:1993-03-29
Release date:1994-07-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of cleaved bovine antithrombin III at 3.2 A resolution.
J.Mol.Biol., 232, 1993
1FCX
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ISOTYPE SELECTIVITY OF THE HUMAN RETINOIC ACID NUCLEAR RECEPTOR HRAR: THE COMPLEX WITH THE RARGAMMA-SELECTIVE RETINOID BMS184394
Descriptor:RETINOIC ACID RECEPTOR GAMMA-1, 6-[HYDROXY-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTALEN-2-YL)-METHYL]-NAPHTALENE-2-CARBOXYLIC ACID, DODECYL-ALPHA-D-MALTOSIDE
Authors:Klaholz, B.P., Mitschler, A., Moras, D., Structural Proteomics in Europe (SPINE)
Deposit date:2000-07-19
Release date:2000-09-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Structural basis for isotype selectivity of the human retinoic acid nuclear receptor.
J.Mol.Biol., 302, 2000
1FCY
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ISOTYPE SELECTIVITY OF THE HUMAN RETINOIC ACID NUCLEAR RECEPTOR HRAR: THE COMPLEX WITH THE RARBETA/GAMMA-SELECTIVE RETINOID CD564
Descriptor:RETINOIC ACID RECEPTOR GAMMA-1, 6-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTALENE-2-CARBONYL)-NAPHTALENE-2-CARBOXYLIC ACID, DODECYL-ALPHA-D-MALTOSIDE
Authors:Klaholz, B.P., Mitschler, A., Moras, D., Structural Proteomics in Europe (SPINE)
Deposit date:2000-07-19
Release date:2000-09-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural basis for isotype selectivity of the human retinoic acid nuclear receptor.
J.Mol.Biol., 302, 2000
1FCZ
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ISOTYPE SELECTIVITY OF THE HUMAN RETINOIC ACID NUCLEAR RECEPTOR HRAR: THE COMPLEX WITH THE PANAGONIST RETINOID BMS181156
Descriptor:RETINOIC ACID RECEPTOR GAMMA-1, 4-[3-OXO-3-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-PROPENYL]-BENZOIC ACID, DODECYL-ALPHA-D-MALTOSIDE
Authors:Klaholz, B.P., Mitschler, A., Moras, D., Structural Proteomics in Europe (SPINE)
Deposit date:2000-07-19
Release date:2000-09-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Structural basis for isotype selectivity of the human retinoic acid nuclear receptor.
J.Mol.Biol., 302, 2000
1FD0
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ISOTYPE SELECTIVITY OF THE HUMAN RETINOIC ACID NUCLEAR RECEPTOR HRAR: THE COMPLEX WITH THE RARGAMMA-SELECTIVE RETINOID SR11254
Descriptor:RETINOIC ACID RECEPTOR GAMMA-1, 6-[HYDROXYIMINO-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTALEN-2-YL)-METHYL]-NAPHTALENE-2-CARBOXYLIC ACID, DODECYL-ALPHA-D-MALTOSIDE
Authors:Klaholz, B.P., Moras, D., Structural Proteomics in Europe (SPINE)
Deposit date:2000-07-19
Release date:2002-09-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:C-H...O hydrogen bonds in the nuclear receptor RARgamma--a potential tool for drug selectivity.
Structure, 10, 2002
1N4H
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CHARACTERIZATION OF LIGANDS FOR THE ORPHAN NUCLEAR RECEPTOR RORBETA
Descriptor:Nuclear Receptor ROR-beta, Steroid Receptor Coactivator-1, RETINOIC ACID
Authors:Stehlin-Gaon, C., Willmann, D., Sanglier, S., Van Dorsselaer, A., Renaud, J.-P., Moras, D., Schuele, R.
Deposit date:2002-10-31
Release date:2003-09-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:All-trans retinoic acid is a ligand for the orphan nuclear receptor RORbeta
Nat.Struct.Biol., 10, 2003
1B76
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GLYCYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH ATP
Descriptor:Glycine--tRNA ligase, ADENOSINE-5'-TRIPHOSPHATE
Authors:Arnez, J.G., Moras, D.
Deposit date:1999-01-27
Release date:1999-01-28
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Glycyl-tRNA synthetase uses a negatively charged pit for specific recognition and activation of glycine.
J.Mol.Biol., 286, 1999
1GGM
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GLYCYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH GLYCYL-ADENYLATE
Descriptor:Glycine--tRNA ligase, GLYCYL-ADENOSINE-5'-PHOSPHATE
Authors:Arnez, J.G., Moras, D.
Deposit date:1999-01-27
Release date:1999-01-28
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Glycyl-tRNA synthetase uses a negatively charged pit for specific recognition and activation of glycine.
J.Mol.Biol., 286, 1999
1KMM
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HISTIDYL-TRNA SYNTHETASE COMPLEXED WITH HISTIDYL-ADENYLATE
Descriptor:HISTIDYL-TRNA SYNTHETASE, HISTIDYL-ADENOSINE MONOPHOSPHATE
Authors:Arnez, J.G., Francklyn, C.S., Moras, D.
Deposit date:1997-05-09
Release date:1997-12-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The first step of aminoacylation at the atomic level in histidyl-tRNA synthetase.
Proc.Natl.Acad.Sci.USA, 94, 1997
1KMN
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HISTIDYL-TRNA SYNTHETASE COMPLEXED WITH HISTIDINOL AND ATP
Descriptor:HISTIDYL-TRNA SYNTHETASE, L-histidinol, ADENOSINE-5'-TRIPHOSPHATE
Authors:Arnez, J.G., Francklyn, C.S., Moras, D.
Deposit date:1997-05-09
Release date:1997-12-17
Last modified:2015-06-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The first step of aminoacylation at the atomic level in histidyl-tRNA synthetase.
Proc.Natl.Acad.Sci.USA, 94, 1997
1KV6
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X-RAY STRUCTURE OF THE ORPHAN NUCLEAR RECEPTOR ERR3 LIGAND-BINDING DOMAIN IN THE CONSTITUTIVELY ACTIVE CONFORMATION
Descriptor:ESTROGEN-RELATED RECEPTOR GAMMA, steroid receptor coactivator 1
Authors:Greschik, H., Wurtz, J.-M., Sanglier, S., Bourguet, W., van Dorsselaer, A., Moras, D., Renaud, J.-P., Structural Proteomics in Europe (SPINE)
Deposit date:2002-01-25
Release date:2003-01-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural and Functional Evidence for Ligand-Independent Transcriptional Activation by the Estrogen-Related Receptor 3
Mol.Cell, 9, 2002