Author results

4JAM
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CRYSTAL STRUCTURE OF BROADLY NEUTRALIZING ANTI-HIV-1 ANTIBODY CH103
Descriptor:ANTIGEN BINDING FRAGMENT OF HEAVY CHAIN of CH103, ANTIGEN BINDING FRAGMENT OF LIGHT CHAIN of CH103, SULFATE ION, ...
Authors:Zhou, T., Moquin, S., Zheng, A., Srivatsan, S., Kwong, P.D.
Deposit date:2013-02-18
Release date:2013-04-03
Last modified:2013-05-29
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus.
Nature, 496, 2013
4JAN
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CRYSTAL STRUCTURE OF BROADLY NEUTRALIZING ANTIBODY CH103 IN COMPLEX WITH HIV-1 GP120
Descriptor:ENVELOPE GLYCOPROTEIN GP120 of HIV-1 clade C, ANTIGEN BINDING FRAGMENT OF HEAVY CHAIN of CH103, ANTIGEN BINDING FRAGMENT OF LIGHT CHAIN of CH103, ...
Authors:Zhou, T., Moquin, S., Zheng, A., Srivatsan, S., Kwong, P.D.
Deposit date:2013-02-18
Release date:2013-04-03
Last modified:2019-01-09
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus.
Nature, 496, 2013
4J6R
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CRYSTAL STRUCTURE OF BROADLY AND POTENTLY NEUTRALIZING ANTIBODY VRC23 IN COMPLEX WITH HIV-1 GP120
Descriptor:Envelope glycoprotein gp160, HEAVY CHAIN OF ANTIBODY VRC23, LIGHT CHAIN OF ANTIBODY VRC23, ...
Authors:Zhou, T., Moquin, S., Kwong, P.D.
Deposit date:2013-02-11
Release date:2013-05-08
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization.
Science, 340, 2013
4RX4
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CRYSTAL STRUCTURE OF VH1-46 GERMLINE-DERIVED CD4-BINDING SITE-DIRECTED ANTIBODY 8ANC134 IN COMPLEX WITH HIV-1 CLADE A Q842.D12 GP120
Descriptor:HIV-1 Clade A Q842.d12 gp120, 8ANC134 Heavy chain, 8ANC134 Light Chain, ...
Authors:Zhou, T., Acharya, P., Moquin, S., Kwong, P.D.
Deposit date:2014-12-08
Release date:2015-07-01
Last modified:2015-07-08
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell(Cambridge,Mass.), 161, 2015
4YDJ
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CRYSTAL STRUCTURE OF BROADLY AND POTENTLY NEUTRALIZING ANTIBODY 44-VRC13.01 IN COMPLEX WITH HIV-1 CLADE AE STRAIN 93TH057 GP120
Descriptor:Envelope glycoprotein gp160,Envelope glycoprotein gp160, HEAVY CHAIN OF ANTIBODY 44-VRC13.01, LIGHT CHAIN OF ANTIBODY 44-VRC13.01, ...
Authors:Zhou, T., Moquin, S., Kwong, P.D.
Deposit date:2015-02-22
Release date:2015-06-03
Last modified:2015-06-17
Method:X-RAY DIFFRACTION (2.308 Å)
Cite:Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell, 161, 2015
4YDK
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CRYSTAL STRUCTURE OF BROADLY AND POTENTLY NEUTRALIZING ANTIBODY C38-VRC16.01 IN COMPLEX WITH HIV-1 CLADE AE STRAIN 93TH057 GP120
Descriptor:Envelope glycoprotein gp160,Envelope glycoprotein gp160, HEAVY CHAIN OF ANTIBODY C38-VRC16.01, LIGHT CHAIN OF ANTIBODY C38-VRC16.01, ...
Authors:Zhou, T., Moquin, S., Zheng, A., Kwong, P.D.
Deposit date:2015-02-22
Release date:2015-06-03
Last modified:2015-06-17
Method:X-RAY DIFFRACTION (2.051 Å)
Cite:Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell, 161, 2015
4YFL
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CRYSTAL STRUCTURE OF VH1-46 GERMLINE-DERIVED CD4-BINDING SITE-DIRECTED ANTIBODY 1B2530 IN COMPLEX WITH HIV-1 CLADE A/E 93TH057 GP120
Descriptor:Envelope glycoprotein gp160,Envelope glycoprotein gp160,Envelope glycoprotein gp160, 1B2530 heavy chain, 1B2530 Light chain, ...
Authors:Acharya, P., Zhou, T., Moquin, S., Kwong, P.D.
Deposit date:2015-02-25
Release date:2015-06-03
Last modified:2015-06-17
Method:X-RAY DIFFRACTION (3.387 Å)
Cite:Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell, 161, 2015
4LSP
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CRYSTAL STRUCTURE OF BROADLY AND POTENTLY NEUTRALIZING ANTIBODY VRC-CH31 IN COMPLEX WITH HIV-1 CLADE A/E GP120 93TH057
Descriptor:HIV-1 CLADE A/E STRAIN 93TH057 GP120, HEAVY CHAIN OF ANTIBODY VRC-CH31, LIGHT CHAIN OF ANTIBODY VRC-CH31, ...
Authors:Zhou, T., Moquin, S., Kwong, P.D.
Deposit date:2013-07-23
Release date:2013-09-04
Last modified:2014-05-07
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies.
Immunity, 39, 2013
4LSQ
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CRYSTAL STRUCTURE OF BROADLY AND POTENTLY NEUTRALIZING ANTIBODY VRC-CH31 IN COMPLEX WITH HIV-1 CLADE A/E GP120 93TH057 WITH LOOP D AND LOOP V5 FROM CLADE A STRAIN 3415_V1_C1
Descriptor:ENVELOPE GLYCOPROTEIN GP120 WITH LOOP D AND V5 FROM STRAIN 3415_V1_C1, HEAVY CHAIN OF ANTIBODY VRC-CH31, LIGHT CHAIN OF ANTIBODY VRC-CH31 WITH N70D MUTATION, ...
Authors:Zhou, T., Moquin, S., Kwong, P.D.
Deposit date:2013-07-23
Release date:2013-08-21
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies.
Immunity, 39, 2013
4LSR
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CRYSTAL STRUCTURE OF BROADLY AND POTENTLY NEUTRALIZING ANTIBODY VRC-CH31 IN COMPLEX WITH HIV-1 CLADE A/E STRAN 93TH057 GP120 WITH LOOP D AND LOOP V5 FROM CLADE A STRAIN KER_2018_11
Descriptor:ENVELOPE GLYCOPROTEIN GP120 WITH LOOP D AND V5 FROM STRAIN ker_2018_11, HEAVY CHAIN OF ANTIBODY VRC-CH31, LIGHT CHAIN OF ANTIBODY VRC-CH31 (N70D MUTATION), ...
Authors:Zhou, T., Moquin, S., Kwong, P.D.
Deposit date:2013-07-23
Release date:2013-08-21
Last modified:2014-05-07
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies.
Immunity, 39, 2013
4LSS
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CRYSTAL STRUCTURE OF BROADLY AND POTENTLY NEUTRALIZING ANTIBODY VRC01 IN COMPLEX WITH HIV-1 CLADE A STRAIN KER_2018_11 GP120
Descriptor:envelope glycoprotein GP120, HEAVY CHAIN OF ANTIBODY VRC01, LIGHT CHAIN OF ANTIBODY VRC01 with N72T mutation, ...
Authors:Zhou, T., Moquin, S., Kwong, P.D.
Deposit date:2013-07-23
Release date:2013-08-21
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies.
Immunity, 39, 2013
4LST
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CRYSTAL STRUCTURE OF BROADLY AND POTENTLY NEUTRALIZING ANTIBODY VRC01 IN COMPLEX WITH HIV-1 CLADE C STRAIN ZM176.66 GP120
Descriptor:ENVELOPE GLYCOPROTEIN GP120 of HIV-1 clade C, HEAVY CHAIN OF ANTIBODY VRC01, LIGHT CHAIN OF ANTIBODY VRC01, ...
Authors:Zhou, T., Moquin, S., Kwong, P.D.
Deposit date:2013-07-23
Release date:2013-08-21
Last modified:2014-05-07
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies.
Immunity, 39, 2013
4LSU
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CRYSTAL STRUCTURE OF BROADLY AND POTENTLY NEUTRALIZING ANTIBODY VRC-PG20 IN COMPLEX WITH HIV-1 CLADE A/E 93TH057 GP120
Descriptor:HIV-1 CLADE A/E STRAIN 93TH057 GP120, HEAVY CHAIN OF ANTIBODY VRC-PG20, LIGHT CHAIN OF ANTIBODY VRC-PG20, ...
Authors:Zhou, T., Moquin, S., Kwong, P.D.
Deposit date:2013-07-23
Release date:2013-08-21
Last modified:2014-05-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies.
Immunity, 39, 2013
4LSV
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CRYSTAL STRUCTURE OF BROADLY AND POTENTLY NEUTRALIZING ANTIBODY 3BNC117 IN COMPLEX WITH HIV-1 CLADE C C1086 GP120
Descriptor:envelope glycoprotein GP120, HEAVY CHAIN OF ANTIBODY 3BNC117, LIGHT CHAIN OF ANTIBODY 3BNC117, ...
Authors:Zhou, T., Moquin, S., Kwong, P.D.
Deposit date:2013-07-23
Release date:2013-08-21
Last modified:2014-05-07
Method:X-RAY DIFFRACTION (3 Å)
Cite:Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies.
Immunity, 39, 2013
5JXA
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CRYSTAL STRUCTURE OF LIGAND-FREE VRC03 ANTIGEN-BINDING FRAGMENT.
Descriptor:VRC03 Heavy chain, VRC03 Light chain, 1,2-ETHANEDIOL, ...
Authors:Zhou, T., Moquin, S., Joyce, M.G., Mascola, J.R., Kwong, P.D.
Deposit date:2016-05-12
Release date:2016-07-27
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Somatic Hypermutation-Induced Changes in the Structure and Dynamics of HIV-1 Broadly Neutralizing Antibodies.
Structure, 24, 2016
3TCL
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CRYSTAL STRUCTURE OF HIV-1 NEUTRALIZING ANTIBODY CH04
Descriptor:CH04 Heavy Chain Fab, CH04 Light Chain Fab, IMIDAZOLE
Authors:Louder, R.K., McLellan, J.S., Pancera, M., Yang, Y., Zhang, B., Bonsignori, M., Kwong, P.D.
Deposit date:2011-08-09
Release date:2011-11-30
Last modified:2011-12-21
Method:X-RAY DIFFRACTION (1.906 Å)
Cite:Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
3U1S
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CRYSTAL STRUCTURE OF HUMAN FAB PGT145, A BROADLY REACTIVE AND POTENT HIV-1 NEUTRALIZING ANTIBODY
Descriptor:Fab PGT145 Light chain, Fab PGT145 Heavy chain, SULFATE ION, ...
Authors:Julien, J.-P., Diwanji, D., Burton, D.R., Wilson, I.A.
Deposit date:2011-09-30
Release date:2011-12-07
Last modified:2011-12-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
3U2S
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CRYSTAL STRUCTURE OF PG9 FAB IN COMPLEX WITH V1V2 REGION FROM HIV-1 STRAIN ZM109
Descriptor:PG9 heavy chain, PG9 light chain, Envelope glycoprotein gp120, ...
Authors:McLellan, J.S., Pancera, M., Kwong, P.D.
Deposit date:2011-10-04
Release date:2011-11-30
Last modified:2011-12-21
Method:X-RAY DIFFRACTION (1.797 Å)
Cite:Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
3U36
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CRYSTAL STRUCTURE OF PG9 FAB
Descriptor:PG9 Fab heavy chain, PG9 Fab light chain, SULFATE ION
Authors:McLellan, J.S., Kwong, P.D.
Deposit date:2011-10-04
Release date:2011-11-30
Last modified:2011-12-21
Method:X-RAY DIFFRACTION (3.281 Å)
Cite:Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
3U46
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CH04H/CH02L P212121
Descriptor:CH04 Heavy chain Fab, CH02 Light chain Fab
Authors:Louder, R., Pancera, M., McLellan, J.S., Kwong, P.D.
Deposit date:2011-10-07
Release date:2011-11-30
Last modified:2011-12-21
Method:X-RAY DIFFRACTION (2.906 Å)
Cite:Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
3U4B
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CH04H/CH02L FAB P4
Descriptor:CH04 Heavy chain, CH02 Light chain
Authors:Pancera, M., Louder, R., Mclellan, J.S., KWong, P.D.
Deposit date:2011-10-07
Release date:2011-11-30
Last modified:2011-12-21
Method:X-RAY DIFFRACTION (2.893 Å)
Cite:Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
3U4E
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CRYSTAL STRUCTURE OF PG9 FAB IN COMPLEX WITH V1V2 REGION FROM HIV-1 STRAIN CAP45
Descriptor:V1V2 region of HIV-1 on 1FD6 scaffold, PG9 Heavy Chain, PG9 Light Chain, ...
Authors:Gorman, J., McLellan, J., Pancera, M., Kwong, P.D.
Deposit date:2011-10-07
Release date:2011-11-30
Last modified:2011-12-21
Method:X-RAY DIFFRACTION (2.185 Å)
Cite:Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
4JB9
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CRYSTAL STRUCTURE OF ANTIBODY VRC06 IN COMPLEX WITH HIV-1 GP120 CORE
Descriptor:clade A/E 93TH057 HIV-1 gp120 core, antibody VRC06 heavy chain, antibody VRC06 light chain, ...
Authors:Kwon, Y.D., Zhou, T., Srivatsan, S., Kwong, P.D.
Deposit date:2013-02-19
Release date:2013-05-08
Last modified:2016-10-19
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization.
Science, 340, 2013
4RWY
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CRYSTAL STRUCTURE OF VH1-46 GERMLINE-DERIVED CD4-BINDING SITE-DIRECTED ANTIBODY 8ANC131 IN COMPLEX WITH HIV-1 CLADE B YU2 GP120
Descriptor:HIV-1 YU2 gp120, Antibody 8ANC131 Heavy chain, Antibody 8ANC131 Light chain, ...
Authors:Acharya, P., Luongo, T.S., Kwong, P.D.
Deposit date:2014-12-08
Release date:2015-07-01
Method:X-RAY DIFFRACTION (2.128 Å)
Cite:Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell(Cambridge,Mass.), 161, 2015
4YDI
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CRYSTAL STRUCTURE OF BROAD AND POTENTLY NEUTRALIZING VRC01-CLASS ANTIBODY Z258-VRC27.01, ISOLATED FROM HUMAN DONOR Z258, IN COMPLEX WITH HIV-1 GP120 FROM CLADE A STRAIN Q23.17
Descriptor:Envelope glycoprotein gp160, HEAVY CHAIN OF ANTIBODY Z258-VRC27.01, LIGHT CHAIN OF ANTIBODY Z258-VRC27.01, ...
Authors:Zhou, T., Srivatsan, S., Kwong, P.D.
Deposit date:2015-02-22
Release date:2015-06-03
Last modified:2015-06-17
Method:X-RAY DIFFRACTION (3.452 Å)
Cite:Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell, 161, 2015
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