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7SQ1
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BU of 7sq1 by Molmil
BG505.MD39TS Env trimer in complex with Fab from antibody C05
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C05 Fab Light chain, ...
Authors:Moore, A, Du, J, Xu, Z, Walker, S, Kulp, D.W, Pallesen, J.
Deposit date:2021-11-04
Release date:2022-06-22
Last modified:2022-12-07
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Induction of tier-2 neutralizing antibodies in mice with a DNA-encoded HIV envelope native like trimer.
Nat Commun, 13, 2022
2K8P
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BU of 2k8p by Molmil
Characterisation of the structural features and interactions of sclerostin: molecular insight into a key regulator of Wnt-mediated bone formation
Descriptor: Sclerostin
Authors:Veverka, V, Henry, A.J, Slocombe, P.M, Ventom, A, Mulloy, B, Muskett, F.W, Muzylak, M, Greenslade, K, Moore, A, Zhang, L, Gong, J, Qian, X, Paszty, C, Taylor, R.J, Robinson, M.K, Carr, M.D.
Deposit date:2008-09-18
Release date:2009-02-17
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Characterization of the Structural Features and Interactions of Sclerostin: Molecular insight into a key regulator of Wnt-mediated bone formation
J.Biol.Chem., 284, 2009
4CNI
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BU of 4cni by Molmil
Crystal structure of the Fab portion of Olokizumab in complex with IL- 6
Descriptor: INTERLEUKIN-6, OLOKIZUMAB HEAVY CHAIN, FAB PORTION, ...
Authors:Shaw, S, Bourne, T, Meier, C, Carrington, B, Gelinas, R, Henry, A, Popplewell, A, Adams, R, Baker, T, Rapecki, S, Marshall, D, Neale, H, Lawson, A.
Deposit date:2014-01-22
Release date:2014-04-30
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Discovery and Characterization of Olokizumab: A Humanized Antibody Targeting Interleukin-6 and Neutralizing Gp130-Signaling.
Mabs, 6, 2014
5C0N
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BU of 5c0n by Molmil
Development of a monoclonal antibody targeting secreted aP2 to treat diabetes and fatty liver disease
Descriptor: Fab CA33 Heavy chain, Fab CA33 light chain, Fatty acid-binding protein, ...
Authors:Doyle, C.
Deposit date:2015-06-12
Release date:2015-06-24
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:Development of a therapeutic monoclonal antibody that targets secreted fatty acid-binding protein aP2 to treat type 2 diabetes.
Sci Transl Med, 7, 2015
5D8J
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BU of 5d8j by Molmil
Development of a therapeutic monoclonal antibody targeting secreted aP2 to treat type 2 diabetes.
Descriptor: Fatty acid-binding protein, adipocyte, HA3 Fab Heavy Chain, ...
Authors:Doyle, C, Birrane, G.
Deposit date:2015-08-17
Release date:2016-01-13
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (3 Å)
Cite:Development of a therapeutic monoclonal antibody that targets secreted fatty acid-binding protein aP2 to treat type 2 diabetes.
Sci Transl Med, 7, 2015
4MMO
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BU of 4mmo by Molmil
The crystal structure of a M20 family metallo-carboxypeptidase Sso-CP2 from Sulfolobus solfataricus
Descriptor: GLYCEROL, SULFATE ION, Sso-CP2 metallo-carboxypetidase, ...
Authors:Dupuy, J, Dutoit, R, Durisotti, V, Demarez, M, Borel, F, Van Elder, D, Legrain, C, Bauvois, C.
Deposit date:2013-09-09
Release date:2014-10-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3363 Å)
Cite:Biochemical characterization of a novel thermostable dinuclear carboxypeptidase from the thermoacidophilic archaeum Sulfolobus solfataricus.
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