Author results

2K8P
  • Download 2k8p
  • View 2k8p
Molmil generated image of 2k8p
CHARACTERISATION OF THE STRUCTURAL FEATURES AND INTERACTIONS OF SCLEROSTIN: MOLECULAR INSIGHT INTO A KEY REGULATOR OF WNT-MEDIATED BONE FORMATION
Descriptor:Sclerostin
Authors:Veverka, V., Henry, A.J., Slocombe, P.M., Ventom, A., Mulloy, B., Muskett, F.W., Muzylak, M., Greenslade, K., Moore, A., Zhang, L., Gong, J., Qian, X., Paszty, C., Taylor, R.J., Robinson, M.K., Carr, M.D.
Deposit date:2008-09-18
Release date:2009-02-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Characterization of the Structural Features and Interactions of Sclerostin: Molecular insight into a key regulator of Wnt-mediated bone formation
J.Biol.Chem., 284, 2009
4CNI
  • Download 4cni
  • View 4cni
Molmil generated image of 4cni
CRYSTAL STRUCTURE OF THE FAB PORTION OF OLOKIZUMAB IN COMPLEX WITH IL- 6
Descriptor:OLOKIZUMAB HEAVY CHAIN, FAB PORTION, OLOKIZUMAB LIGHT CHAIN, ...
Authors:Shaw, S., Bourne, T., Meier, C., Carrington, B., Gelinas, R., Henry, A., Popplewell, A., Adams, R., Baker, T., Rapecki, S., Marshall, D., Neale, H., Lawson, A.
Deposit date:2014-01-22
Release date:2014-04-30
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Discovery and Characterization of Olokizumab: A Humanized Antibody Targeting Interleukin-6 and Neutralizing Gp130-Signaling.
Mabs, 6, 2014
5C0N
  • Download 5c0n
  • View 5c0n
Molmil generated image of 5c0n
DEVELOPMENT OF A MONOCLONAL ANTIBODY TARGETING SECRETED AP2 TO TREAT DIABETES AND FATTY LIVER DISEASE
Descriptor:Fatty acid-binding protein, adipocyte, Fab CA33 Heavy chain, ...
Authors:Doyle, C.
Deposit date:2015-06-12
Release date:2015-06-24
Last modified:2016-01-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Development of a therapeutic monoclonal antibody that targets secreted fatty acid-binding protein aP2 to treat type 2 diabetes.
Sci Transl Med, 7, 2015
5D8J
  • Download 5d8j
  • View 5d8j
Molmil generated image of 5d8j
DEVELOPMENT OF A THERAPEUTIC MONOCLONAL ANTIBODY TARGETING SECRETED AP2 TO TREAT TYPE 2 DIABETES.
Descriptor:Fatty acid-binding protein, adipocyte, HA3 Fab Heavy Chain, ...
Authors:Doyle, C., Birrane, G.
Deposit date:2015-08-17
Release date:2016-01-13
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (3 Å)
Cite:Development of a therapeutic monoclonal antibody that targets secreted fatty acid-binding protein aP2 to treat type 2 diabetes.
Sci Transl Med, 7, 2015