Author results

2TSC
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STRUCTURE, MULTIPLE SITE BINDING, AND SEGMENTAL ACCOMODATION IN THYMIDYLATE SYNTHASE ON BINDING D/UMP AND AN ANTI-FOLATE
Descriptor:THYMIDYLATE SYNTHASE, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID
Authors:Montfort, W.R., Stroud, R.M.
Deposit date:1991-07-03
Release date:1991-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structure, multiple site binding, and segmental accommodation in thymidylate synthase on binding dUMP and an anti-folate.
Biochemistry, 29, 1990
2FTQ
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E. COLI THYMIDYLATE SYNTHASE AT 1.8 A RESOLUTION
Descriptor:Thymidylate synthase, PHOSPHATE ION, SULFATE ION
Authors:Montfort, W.R., Roberts, S.A.
Deposit date:2006-01-24
Release date:2006-05-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Subtle Conformational Differences between Escherichia coli Thymidylate Synthase and Specific Mutants of this Enzyme
To be Published
3PAV
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THE REDUCED FORM OF CUEO
Descriptor:Blue copper oxidase cueO, COPPER (II) ION
Authors:Montfort, W.R., Roberts, S.A., Singh, S.K.
Deposit date:2010-10-19
Release date:2011-10-19
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:The reduced form of CueO
To be Published
3FLL
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CRYSTAL STRUCTURE OF E55Q MUTANT OF NITROPHORIN 4
Descriptor:Nitrophorin-4, PROTOPORPHYRIN IX CONTAINING FE, AMMONIA
Authors:Montfort, W.R., Weichsel, A.
Deposit date:2008-12-18
Release date:2009-02-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Effect of mutation of carboxyl side-chain amino acids near the heme on the midpoint potentials and ligand binding constants of nitrophorin 2 and its NO, histamine, and imidazole complexes.
J.Am.Chem.Soc., 131, 2009
2FTN
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E. COLI THYMIDYLATE SYNTHASE Y94F MUTANT
Descriptor:Thymidylate synthase, SULFATE ION
Authors:Montfort, W.R., Roberts, S.A.
Deposit date:2006-01-24
Release date:2006-05-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of the Y94F mutant of Escherichia coli thymidylate synthase.
ACTA CRYSTALLOGR.,SECT.F, 62, 2006
3NSD
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SILVER BOUND TO THE MULTICOPPER OXIDASE CUEO (UNTAGGED)
Descriptor:Blue copper oxidase cueO, COPPER (II) ION, SILVER ION, ...
Authors:Montfort, W.R., Roberts, S.A., Singh, S.K.
Deposit date:2010-07-01
Release date:2011-08-17
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of multicopper oxidase CueO bound to copper(I) and silver(I): functional role of a methionine-rich sequence.
J. Biol. Chem., 286, 2011
3OD3
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CUEO AT 1.1 A RESOLUTION INCLUDING RESIDUES IN PREVIOUSLY DISORDERED REGION
Descriptor:Blue copper oxidase cueO, COPPER (II) ION, OXYGEN ATOM, ...
Authors:Montfort, W.R., Roberts, S.A., Singh, S.K.
Deposit date:2010-08-10
Release date:2011-09-07
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Crystal structures of multicopper oxidase CueO bound to copper(I) and silver(I): functional role of a methionine-rich sequence.
J. Biol. Chem., 286, 2011
3QQX
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REDUCED NATIVE INTERMEDIATE OF THE MULTICOPPER OXIDASE CUEO
Descriptor:Blue copper oxidase CueO, COPPER (II) ION, COPPER (I) ION, ...
Authors:Montfort, W.R., Roberts, S.A., Singh, S.K.
Deposit date:2011-02-16
Release date:2012-02-29
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:CueO E506D Mutant: Crystal Structure of Reduced Native Intermediate, Kinetics, and Impairment of Product Release
To be Published
1AJM
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CRYSTAL STRUCTURE OF THYMIDYLATE SYNTHASE R126E MUTANT
Descriptor:THYMIDYLATE SYNTHASE
Authors:Strop, P., Montfort, W.R.
Deposit date:1997-05-06
Release date:1997-11-12
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of a marginally active thymidylate synthase mutant, Arg 126-->Glu.
Protein Sci., 6, 1997
1EQD
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CRYSTAL STRUCTURE OF NITROPHORIN 4 COMPLEXED WITH CN
Descriptor:NITROPHORIN 4, CYANIDE ION, 5,8-DIMETHYL-1,2,3,4-TETRAVINYLPORPHINE-6,7-DIPROPIONIC ACID FERROUS COMPLEX, ...
Authors:Weichsel, A., Andersen, J.F., Roberts, S.A., Montfort, W.R.
Deposit date:2000-04-03
Release date:2000-05-03
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Nitric oxide binding to nitrophorin 4 induces complete distal pocket burial.
Nat.Struct.Biol., 7, 2000
1ERX
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CRYSTAL STRUCTURE OF NITROPHORIN 4 COMPLEXED WITH NO
Descriptor:NITROPHORIN 4, 5,8-DIMETHYL-1,2,3,4-TETRAVINYLPORPHINE-6,7-DIPROPIONIC ACID FERROUS COMPLEX, NITRIC OXIDE, ...
Authors:Weichsel, A., Andersen, J.F., Roberts, S.A., Montfort, W.R.
Deposit date:2000-04-06
Release date:2000-05-03
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Nitric oxide binding to nitrophorin 4 induces complete distal pocket burial.
Nat.Struct.Biol., 7, 2000
1PEE
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CRYSTAL STRUCTURE OF NITROPHORIN 2 COMPLEX WITH IMIDAZOLE
Descriptor:Nitrophorin 2, PROTOPORPHYRIN IX CONTAINING FE, IMIDAZOLE
Authors:Weihsel, A., Montfort, W.R.
Deposit date:2003-05-21
Release date:2004-06-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Conformational change and heme ruffling in nitrophorin 2, a nitric oxide carrier from kissing bug.
To be Published
1PM1
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CRYSTAL STRUCTURE OF NITROPHORIN 2 L122V/L132V MUTANT COMPLEX WITH IMIDAZOLE
Descriptor:Nitrophorin 2, PROTOPORPHYRIN IX CONTAINING FE, IMIDAZOLE
Authors:Weichsel, A., Montfort, W.R.
Deposit date:2003-06-09
Release date:2004-06-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Conformational change and heme ruffling in nitrophorin 2, a nitric oxide carrier from kissing bug
To be Published
1T68
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CRYSTAL STRUCTURE OF NITROPHORIN 2 COMPLEX WITH NO
Descriptor:Nitrophorin 2, PROTOPORPHYRIN IX CONTAINING FE, NITRIC OXIDE
Authors:Weichsel, A., Montfort, W.R.
Deposit date:2004-05-05
Release date:2005-05-17
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Conformational change and heme ruffling in nitrophorin 2, a nitric oxide carrier from kissing bug
To be Published
1TSD
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THYMIDYLATE SYNTHASE COMPLEX WITH 2'-DEOXYURIDINE 5'-MONOPHOSPHATE (DUMP) AND FOLATE ANALOG 1843U89
Descriptor:THYMIDYLATE SYNTHASE, BETA-MERCAPTOETHANOL, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, ...
Authors:Weichsel, A., Montfort, W.R.
Deposit date:1995-08-15
Release date:1996-01-29
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Ligand-induced distortion of an active site in thymidylate synthase upon binding anticancer drug 1843U89.
Nat.Struct.Biol., 2, 1995
1U0X
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CRYSTAL STRUCTURE OF NITROPHORIN 4 UNDER PRESSURE OF XENON (200 PSI)
Descriptor:Nitrophorin 4, PROTOPORPHYRIN IX CONTAINING FE, AMMONIA, ...
Authors:Nienhaus, K., Maes, E.M., Weichsel, A., Montfort, W.R., Nienhaus, G.U.
Deposit date:2004-07-14
Release date:2004-07-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structural dynamics controls nitric oxide affinity in nitrophorin 4
J.Biol.Chem., 279, 2004
3M9J
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CRYSTAL STRUCTURE OF HUMAN THIOREDOXIN C69/73S DOUBLE MUTANT, REDUCED FORM
Descriptor:Thioredoxin
Authors:Weichsel, A., Montfort, W.R.
Deposit date:2010-03-22
Release date:2010-08-11
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Crystal structure of human thioredoxin revealing an unraveled helix and exposed S-nitrosation site.
Protein Sci., 19, 2010
3M9K
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CRYSTAL STRUCTURE OF HUMAN THIOREDOXIN C69/73S DOUBLE-MUTANT, OXIDIZED FORM
Descriptor:Thioredoxin, SULFATE ION, (4S,5S)-1,2-DITHIANE-4,5-DIOL
Authors:Weichsel, A., Montfort, W.R.
Deposit date:2010-03-22
Release date:2010-08-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of human thioredoxin revealing an unraveled helix and exposed S-nitrosation site.
Protein Sci., 19, 2010
4GRJ
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CRYSTAL STRUCTURE OF NITROPHORIN 4 TRIPLE MUTANT COMPLEX WITH NO
Descriptor:Nitrophorin-4, PROTOPORPHYRIN IX CONTAINING FE, NITRIC OXIDE, ...
Authors:Weichsel, A., Issaian, A.V., Montfort, W.R.
Deposit date:2012-08-24
Release date:2013-08-07
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Crystal structures of nitrophorin 4 triple mutant
To be Published
4NP1
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NITROPHORIN 1 COMPLEX WITH NITRIC OXIDE
Descriptor:NITROPHORIN 1, PROTOPORPHYRIN IX CONTAINING FE, NITRIC OXIDE, ...
Authors:Weichsel, A., Andersen, J.F., Walker, F.A., Montfort, W.R.
Deposit date:1998-06-26
Release date:1998-11-11
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Nitric Oxide Binding to the Ferri-and Ferroheme States of Nitrophorin 1, a Reversible No-Binding Heme Protein from the Saliva of the Blood-Sucking Insect, Rhodnius Prolixus
To be Published
1AUC
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HUMAN THIOREDOXIN (OXIDIZED WITH DIAMIDE)
Descriptor:THIOREDOXIN
Authors:Anderson, J.F., Sanders, D.A.R., Gasdaska, J., Weichsel, A., Powis, G., Montfort, W.R.
Deposit date:1997-08-22
Release date:1998-02-25
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Human thioredoxin homodimers: regulation by pH, role of aspartate 60, and crystal structure of the aspartate 60 --> asparagine mutant.
Biochemistry, 36, 1997
1ML7
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CRYSTAL STRUCTURE OF NITROPHORIN 4 COMPLEXED WITH 4-IODOPYRAZOLE
Descriptor:nitrophorin 4, 5,8-DIMETHYL-1,2,3,4-TETRAVINYLPORPHINE-6,7-DIPROPIONIC ACID FERROUS COMPLEX, 4-IODOPYRAZOLE
Authors:Berry, R.E., Ding, X.D., Weichsel, A., Montfort, W.R., Walker, F.A.
Deposit date:2002-08-30
Release date:2002-09-20
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Axial ligand complexes of the Rhodnius nitrophorins: reduction potentials, binding constants, EPR spectra, and structures of the 4-iodopyrazole and imidazole complexes of NP4
J.Biol.Inorg.Chem., 9, 2004
1NP1
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CRYSTAL STRUCTURE OF THE COMPLEX OF NITROPHORIN 1 FROM RHODNIUS PROLIXUS WITH HISTAMINE
Descriptor:NITROPHORIN 1, PHOSPHATE ION, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Weichsel, A., Montfort, W.R.
Deposit date:1998-01-19
Release date:1998-05-27
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of a nitric oxide transport protein from a blood-sucking insect.
Nat.Struct.Biol., 5, 1998
1NTF
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CRYSTAL STRUCTURE OF CIMEX NITROPHORIN
Descriptor:salivary nitrophorin, PROTOPORPHYRIN IX CONTAINING FE
Authors:Weichsel, A., Maes, E.M., Andersen, J.F., Valenzuela, J.G., Walker, F.A., Montfort, W.R.
Deposit date:2003-01-29
Release date:2004-03-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Heme-assisted S-nitrosation of a proximal thiolate in a nitric oxide transport protein.
Proc.Natl.Acad.Sci.USA, 102, 2005
1SI6
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CRYSTAL STRUCTURE OF CIMEX NITROPHORIN COMPLEX WITH CO
Descriptor:salivary nitrophorin, CARBON MONOXIDE, PROTOPORPHYRIN IX CONTAINING FE
Authors:Weichsel, A., Montfort, W.R.
Deposit date:2004-02-27
Release date:2005-03-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure of cimex nitrophorin complex with carbon monoxide
To be Published