Author results

2X5J
  • Download 2x5j
  • View 2x5j
Molmil generated image of 2x5j
CRYSTAL STRUCTURE OF THE APOFORM OF THE D-ERYTHROSE-4-PHOSPHATE DEHYDROGENASE FROM E. COLI
分子名称:D-ERYTHROSE-4-PHOSPHATE DEHYDROGENASE, PHOSPHATE ION
著者Moniot, S., Didierjean, C., Boschi-Muller, S., Branlant, G., Corbier, C.
登録日2010-02-09
公開日2011-02-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Characterization of Erythrose-4- Phosphate Dehydrogenase from Escherichia Coli: Peculiar Features When Compared to Phosphorylating Gapdhs
To be Published
2X5K
  • Download 2x5k
  • View 2x5k
Molmil generated image of 2x5k
STRUCTURE OF AN ACTIVE SITE MUTANT OF THE D-ERYTHROSE-4-PHOSPHATE DEHYDROGENASE FROM E. COLI
分子名称:D-ERYTHROSE-4-PHOSPHATE DEHYDROGENASE, GLYCEROL, 1,2-ETHANEDIOL, ...
著者Moniot, S., Didierjean, C., Boschi-Muller, S., Branlant, G., Corbier, C.
登録日2010-02-10
公開日2011-02-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Structural Characterization of Erythrose-4- Phosphate Dehydrogenase from Escherichia Coli: Peculiar Features When Compared to Phosphorylating Gapdhs
To be Published
2XF8
  • Download 2xf8
  • View 2xf8
Molmil generated image of 2xf8
STRUCTURE OF THE D-ERYTHROSE-4-PHOSPHATE DEHYDROGENASE FROM E. COLI IN COMPLEX WITH A NAD COFACTOR ANALOG (3-CHLOROACETYL ADENINE PYRIDINE DINUCLEOTIDE) AND SULFATE ANION
分子名称:D-ERYTHROSE-4-PHOSPHATE DEHYDROGENASE, SULFATE ION, 3-(CHLOROACETYL) PYRIDINE ADENINE DINUCLEOTIDE
著者Moniot, S., Didierjean, C., Boschi-Muller, S., Branlant, G., Corbier, C.
登録日2010-05-20
公開日2011-06-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structural Characterization of Erythrose-4- Phosphate Dehydrogenase from Escherichia Coli: Peculiar Features When Compared to Phosphorylating Gapdhs
To be Published
3CMC
  • Download 3cmc
  • View 3cmc
Molmil generated image of 3cmc
THIOACYLENZYME INTERMEDIATE OF BACILLUS STEAROTHERMOPHILUS PHOSPHORYLATING GAPDH
分子名称:Glyceraldehyde-3-phosphate dehydrogenase, SULFATE ION, GLYCERALDEHYDE-3-PHOSPHATE, ...
著者Moniot, S., Vonrhein, C., Bricogne, G., Didierjean, C., Corbier, C.
登録日2008-03-21
公開日2008-06-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Trapping of the Thioacylglyceraldehyde-3-phosphate Dehydrogenase Intermediate from Bacillus stearothermophilus: DIRECT EVIDENCE FOR A FLIP-FLOP MECHANISM
J.Biol.Chem., 283, 2008
3ZGO
  • Download 3zgo
  • View 3zgo
Molmil generated image of 3zgo
RE-REFINED STRUCTURE OF THE HUMAN SIRT2 APOFORM
分子名称:NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-2, ZINC ION, HEXAETHYLENE GLYCOL, ...
著者Moniot, S., Steegborn, C.
登録日2012-12-18
公開日2013-03-20
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Crystal Structure Analysis of Human Sirt2 and its Adp-Ribose Complex
J.Struct.Biol., 182, 2013
3ZGV
  • Download 3zgv
  • View 3zgv
Molmil generated image of 3zgv
STRUCTURE OF HUMAN SIRT2 IN COMPLEX WITH ADP-RIBOSE
分子名称:NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-2, ZINC ION, ACETATE ION, ...
著者Moniot, S., Steegborn, C.
登録日2012-12-19
公開日2013-03-13
最終更新日2013-05-08
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Crystal Structure Analysis of Human Sirt2 and its Adp-Ribose Complex
J.Struct.Biol., 182, 2013
5MAR
  • Download 5mar
  • View 5mar
Molmil generated image of 5mar
STRUCTURE OF HUMAN SIRT2 IN COMPLEX WITH 1,2,4-OXADIAZOLE INHIBITOR AND ADP RIBOSE.
分子名称:NAD-dependent protein deacetylase sirtuin-2, ZINC ION, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE, ...
著者Moniot, S., Steegborn, C.
登録日2016-11-04
公開日2017-03-15
最終更新日2017-04-05
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Development of 1,2,4-Oxadiazoles as Potent and Selective Inhibitors of the Human Deacetylase Sirtuin 2: Structure-Activity Relationship, X-ray Crystal Structure, and Anticancer Activity.
J. Med. Chem., 60, 2017
2Q9T
  • Download 2q9t
  • View 2q9t
Molmil generated image of 2q9t
HIGH-RESOLUTION STRUCTURE OF THE DING PROTEIN FROM PSEUDOMONAS FLUORESCENS
分子名称:DING, PHOSPHATE ION, ACETATE ION, ...
著者Moniot, S., Ahn, S., Elias, M., Kim, D., Scott, K., Chabriere, E.
登録日2007-06-14
公開日2008-06-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Structure-function relationships in a bacterial DING protein.
Febs Lett., 581, 2007
5MAT
  • Download 5mat
  • View 5mat
Molmil generated image of 5mat
STRUCTURE OF HUMAN SIRTUIN 2 IN COMPLEX WITH A SELECTIVE THIENOPYRIMIDINONE BASED INHIBITOR
分子名称:NAD-dependent protein deacetylase sirtuin-2, ZINC ION, (7~{R})-7-[(3,5-dimethyl-1,2-oxazol-4-yl)methylamino]-3-[(4-methoxynaphthalen-1-yl)methyl]-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-one, ...
著者Moniot, S., Steegborn, C.
登録日2016-11-04
公開日2017-02-08
最終更新日2017-03-22
実験手法X-RAY DIFFRACTION (2.069 Å)
主引用文献Thienopyrimidinone Based Sirtuin-2 (SIRT2)-Selective Inhibitors Bind in the Ligand Induced Selectivity Pocket.
J. Med. Chem., 60, 2017
6FFM
  • Download 6ffm
  • View 6ffm
Molmil generated image of 6ffm
CRYSTAL STRUCTURE OF HUMAN KEAP1 BTB DOMAIN IN COMPLEX WITH ISOXAZOLINE-BASED INHIBITOR
分子名称:Kelch-like ECH-associated protein 1, ~{N}-[4-[(5~{R})-4,5-dihydro-1,2-oxazol-5-yl]phenyl]ethanamide
著者Moniot, S., Steegborn, C.
登録日2018-01-08
公開日2018-11-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Effects of 3-Bromo-4,5-dihydroisoxazole Derivatives on Nrf2 Activation and Heme Oxygenase-1 Expression.
ChemistryOpen, 7, 2018
2YHW
  • Download 2yhw
  • View 2yhw
Molmil generated image of 2yhw
HIGH-RESOLUTION CRYSTAL STRUCTURES OF N-ACETYLMANNOSAMINE KINASE: INSIGHTS ABOUT SUBSTRATE SPECIFICITY, ACTIVITY AND INHIBITOR MODELLING.
分子名称:BIFUNCTIONAL UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE/N-ACETYLMANNOSAMINE KINASE, 2-(ACETYLAMINO)-2-DEOXY-ALPHA-D-MANNOPYRANOSE, ZINC ION, ...
著者Martinez, J., Nguyen, L.D., Tauberger, E., Hinderlich, S., Zimmer, R., Tauberger, E., Reutter, W., Saenger, W., Fan, H., Moniot, S.
登録日2011-05-08
公開日2012-02-29
最終更新日2012-05-02
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Crystal Structures of N-Acetylmannosamine Kinase Provide Insights Into Enzyme Specificity and Inhibition
J.Biol.Chem., 287, 2012
2YHY
  • Download 2yhy
  • View 2yhy
Molmil generated image of 2yhy
STRUCTURE OF N-ACETYLMANNOSAMINE KINASE IN COMPLEX WITH N- ACETYLMANNOSAMINE AND ADP
分子名称:BIFUNCTIONAL UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE/N-ACETYLMANNOSAMINE KINASE, 2-(ACETYLAMINO)-2-DEOXY-ALPHA-D-MANNOPYRANOSE, CALCIUM ION, ...
著者Martinez, J., Nguyen, L.D., Tauberger, E., Hinderlich, S., Reutter, W., Fan, H., Saenger, W., Moniot, S.
登録日2011-05-10
公開日2012-02-29
最終更新日2012-05-02
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Crystal Structures of N-Acetylmannosamine Kinase Provide Insights Into Enzyme Specificity and Inhibition
J.Biol.Chem., 287, 2012
2YI1
  • Download 2yi1
  • View 2yi1
Molmil generated image of 2yi1
CRYSTAL STRUCTURE OF N-ACETYLMANNOSAMINE KINASE IN COMPLEX WITH N- ACETYL MANNOSAMINE 6-PHOSPHATE AND ADP.
分子名称:BIFUNCTIONAL UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE/N-ACETYLMANNOSAMINE KINASE, 2-(ACETYLAMINO)-2-DEOXY-6-O-PHOSPHONO-ALPHA-D-MANNOPYRANOSE, 2-(ACETYLAMINO)-2-DEOXY-ALPHA-D-MANNOPYRANOSE, ...
著者Martinez, J., Nguyen, L.D., Tauberger, E., Hinderlich, S., Reutter, W., Fan, H., Saenger, W., Moniot, S.
登録日2011-05-10
公開日2012-02-29
最終更新日2012-05-02
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal Structures of N-Acetylmannosamine Kinase Provide Insights Into Enzyme Specificity and Inhibition
J.Biol.Chem., 287, 2012
2YJP
  • Download 2yjp
  • View 2yjp
Molmil generated image of 2yjp
CRYSTAL STRUCTURE OF THE SOLUTE RECEPTORS FOR L-CYSTEINE OF NEISSERIA GONORRHOEAE
分子名称:PUTATIVE ABC TRANSPORTER, PERIPLASMIC BINDING PROTEIN, AMINO ACID, ...
著者Bulut, H., Moniot, S., Scheffel, F., Gathmann, S., Licht, A., Saenger, W., Schneider, E.
登録日2011-05-23
公開日2011-12-14
最終更新日2012-01-25
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Crystal Structures of Two Solute Receptors for L-Cystine and L-Cysteine, Respectively, of the Human Pathogen Neisseria Gonorrhoeae.
J.Mol.Biol., 415, 2012
2YLN
  • Download 2yln
  • View 2yln
Molmil generated image of 2yln
CRYSTAL STRUCTURE OF THE L-CYSTINE SOLUTE RECEPTOR OF NEISSERIA GONORRHOEAE IN THE CLOSED CONFORMATION
分子名称:PUTATIVE ABC TRANSPORTER, PERIPLASMIC BINDING PROTEIN, AMINO ACID, ...
著者Bulut, H., Moniot, S., Scheffel, F., Gathmann, S., Licht, A., Saenger, W., Schneider, E.
登録日2011-06-03
公開日2011-12-14
最終更新日2012-01-25
実験手法X-RAY DIFFRACTION (1.12 Å)
主引用文献Crystal Structures of Two Solute Receptors for L-Cystine and L-Cysteine, Respectively, of the Human Pathogen Neisseria Gonorrhoeae.
J.Mol.Biol., 415, 2012
3ZSF
  • Download 3zsf
  • View 3zsf
Molmil generated image of 3zsf
CRYSTAL STRUCTURE OF THE L-CYSTINE SOLUTE RECEPTOR OF NEISSERIA GONORRHOEAE IN THE UNLIGANDED OPEN CONFORMATION
分子名称:ABC TRANSPORTER, PERIPLASMIC BINDING PROTEIN, AMINO ACID
著者Bulut, H., Moniot, S., Scheffel, F., Gathmann, S., Licht, A., Saenger, W., Schneider, E.
登録日2011-06-27
公開日2011-12-14
最終更新日2012-01-25
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Crystal Structures of Two Solute Receptors for L-Cystine and L-Cysteine, Respectively, of the Human Pathogen Neisseria Gonorrhoeae.
J.Mol.Biol., 415, 2012
4CLF
  • Download 4clf
  • View 4clf
Molmil generated image of 4clf
CRYSTAL STRUCTURE OF HUMAN SOLUBLE ADENYLYL CYCLASE (APO FORM)
分子名称:ADENYLATE CYCLASE TYPE 10, ACETATE ION, GLYCEROL
著者Kleinboelting, S., Moniot, S., Weyand, M., Steegborn, C.
登録日2014-01-14
公開日2014-03-05
最終更新日2019-04-03
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structures of Human Soluble Adenylyl Cyclase Reveal Mechanisms of Catalysis and of its Activation Through Bicarbonate.
Proc.Natl.Acad.Sci.USA, 111, 2014
2VC5
  • Download 2vc5
  • View 2vc5
Molmil generated image of 2vc5
STRUCTURAL BASIS FOR NATURAL LACTONASE AND PROMISCUOUS PHOSPHOTRIESTERASE ACTIVITIES
分子名称:ARYLDIALKYLPHOSPHATASE, FE (III) ION, COBALT (II) ION, ...
著者Elias, M., Dupuy, J., Merone, L., Mandrich, L., Moniot, S., Lecomte, C., Rossi, M., Masson, P., Manco, G., Chabriere, E.
登録日2007-09-18
公開日2008-04-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Basis for Natural Lactonase and Promiscuous Phosphotriesterase Activities.
J.Mol.Biol., 379, 2008
2VC7
  • Download 2vc7
  • View 2vc7
Molmil generated image of 2vc7
STRUCTURAL BASIS FOR NATURAL LACTONASE AND PROMISCUOUS PHOSPHOTRIESTERASE ACTIVITIES
分子名称:ARYLDIALKYLPHOSPHATASE, FE (III) ION, COBALT (II) ION, ...
著者Elias, M., Dupuy, J., Merone, L., Mandrich, L., Moniot, S., Rochu, D., Lecomte, C., Rossi, M., Masson, P., Manco, G., Chabriere, E.
登録日2007-09-19
公開日2008-04-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural Basis for Natural Lactonase and Promiscuous Phosphotriesterase Activities.
J.Mol.Biol., 379, 2008
4F1U
  • Download 4f1u
  • View 4f1u
Molmil generated image of 4f1u
SUBATOMIC RESOLUTION STRUCTURE OF A HIGH AFFINITY PERIPLASMIC PHOSPHATE-BINDING PROTEIN (PFLUDING) BOUND WITH PHOSPHATE AT PH 4.5
分子名称:Putative alkaline phosphatase, HYDROGENPHOSPHATE ION, 1,2-ETHANEDIOL, ...
著者Liebschner, D., Elias, M., Tawfik, D.S., Moniot, S., Fournier, B., Scott, K., Jelsch, C., Guillot, B., Lecomte, C., Chabriere, E.
登録日2012-05-07
公開日2012-05-23
最終更新日2012-11-21
実験手法X-RAY DIFFRACTION (0.98 Å)
主引用文献The molecular basis of phosphate discrimination in arsenate-rich environments.
Nature, 491, 2012
4F1V
  • Download 4f1v
  • View 4f1v
Molmil generated image of 4f1v
SUBATOMIC RESOLUTION STRUCTURE OF A HIGH AFFINITY PERIPLASMIC PHOSPHATE-BINDING PROTEIN (PFLUDING) BOUND WITH PHOSPHATE AT PH 8.5
分子名称:Putative alkaline phosphatase, HYDROGENPHOSPHATE ION, SULFATE ION
著者Liebschner, D., Elias, M., Tawfik, D.S., Moniot, S., Fournier, B., Scott, K., Jelsch, C., Guillot, B., Lecomte, C., Chabriere, E.
登録日2012-05-07
公開日2012-05-23
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (0.88 Å)
主引用文献The molecular basis of phosphate discrimination in arsenate-rich environments.
Nature, 491, 2012
3OG9
  • Download 3og9
  • View 3og9
Molmil generated image of 3og9
STRUCTURE OF YAHD WITH MALIC ACID
分子名称:protein yahD a copper inducible hydrolase, D-MALATE
著者Martinez Font, J., Mancini, S., Tauberger, E., Moniot, S.
登録日2010-08-16
公開日2010-12-15
最終更新日2013-06-19
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Regulation and structure of YahD, a copper inducible alpha/beta hydrolase of Lactococcus lactis IL1403
Fems Microbiol.Lett., 314, 2011
4CLK
  • Download 4clk
  • View 4clk
Molmil generated image of 4clk
CRYSTAL STRUCTURE OF HUMAN SOLUBLE ADENYLYL CYCLASE IN COMPLEX WITH ALPHA,BETA-METHYLENEADENOSINE-5'-TRIPHOSPHATE
分子名称:ADENYLATE CYCLASE TYPE 10, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, CHLORIDE ION, ...
著者Kleinboelting, S., Weyand, M., Steegborn, C.
登録日2014-01-15
公開日2014-03-05
最終更新日2019-04-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structures of Human Soluble Adenylyl Cyclase Reveal Mechanisms of Catalysis and of its Activation Through Bicarbonate.
Proc.Natl.Acad.Sci.USA, 111, 2014
4CLL
  • Download 4cll
  • View 4cll
Molmil generated image of 4cll
CRYSTAL STRUCTURE OF HUMAN SOLUBLE ADENYLYL CYCLASE IN COMPLEX WITH BICARBONATE
分子名称:ADENYLATE CYCLASE TYPE 10, BICARBONATE ION, 1,2-ETHANEDIOL, ...
著者Kleinboelting, S., Weyand, M., Steegborn, C.
登録日2014-01-15
公開日2014-03-05
最終更新日2019-04-03
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structures of Human Soluble Adenylyl Cyclase Reveal Mechanisms of Catalysis and of its Activation Through Bicarbonate.
Proc.Natl.Acad.Sci.USA, 111, 2014
4CLP
  • Download 4clp
  • View 4clp
Molmil generated image of 4clp
CRYSTAL STRUCTURE OF HUMAN SOLUBLE ADENYLYL CYCLASE COMPLEX WITH ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE
分子名称:ADENYLATE CYCLASE TYPE 10, ACETATE ION, GLYCEROL, ...
著者Kleinboelting, S., Weyand, M., Steegborn, C.
登録日2014-01-15
公開日2014-03-05
最終更新日2019-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structures of Human Soluble Adenylyl Cyclase Reveal Mechanisms of Catalysis and of its Activation Through Bicarbonate.
Proc.Natl.Acad.Sci.USA, 111, 2014
<12>