Author results

1US8
  • Download 1us8
  • View 1us8
Molmil generated image of 1us8
THE RAD50 SIGNATURE MOTIF: ESSENTIAL TO ATP BINDING AND BIOLOGICAL FUNCTION
Descriptor:DNA DOUBLE-STRAND BREAK REPAIR RAD50 ATPASE
Authors:Moncalian, G., Lengsfeld, B., Bhaskara, V., Hopfner, K.P., Karcher, A., Alden, E., Tainer, J.A., Paull, T.T.
Deposit date:2003-11-20
Release date:2003-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Rad50 Signature Motif: Essential to ATP Binding and Biological Function
J.Mol.Biol., 335, 2004
2J6F
  • Download 2j6f
  • View 2j6f
Molmil generated image of 2j6f
N-TERMINAL SH3 DOMAIN OF CMS (CD2AP HUMAN HOMOLOG) BOUND TO CBL-B PEPTIDE
Descriptor:CD2-ASSOCIATED PROTEIN, E3 UBIQUITIN-PROTEIN LIGASE CBL-B
Authors:Moncalian, G., Cardenes, N., Deribe, Y.L., Spinola-Amilibia, M., Dikic, I., Bravo, J.
Deposit date:2006-09-28
Release date:2006-10-11
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Atypical Polyproline Recognition by the Cms N- Terminal SH3 Domain.
J.Biol.Chem., 281, 2006
2J6K
  • Download 2j6k
  • View 2j6k
Molmil generated image of 2j6k
N-TERMINAL SH3 DOMAIN OF CMS (CD2AP HUMAN HOMOLOG)
Descriptor:CD2-ASSOCIATED PROTEIN, SODIUM ION
Authors:Moncalian, G., Cardenes, N., Deribe, Y.L., Spinola-Amilibia, M., Dikic, I., Bravo, J.
Deposit date:2006-09-29
Release date:2006-10-11
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Atypical Polyproline Recognition by the Cms N- Terminal SH3 Domain.
J.Biol.Chem., 281, 2006
2J6O
  • Download 2j6o
  • View 2j6o
Molmil generated image of 2j6o
ATYPICAL POLYPROLINE RECOGNITION BY THE CMS N-TERMINAL SH3 DOMAIN. CMS:CD2 HETEROTRIMER
Descriptor:CD2-ASSOCIATED PROTEIN, T-CELL SURFACE ANTIGEN CD2
Authors:Moncalian, G., Cardenes, N., Deribe, Y.L., Spinola-Amilibia, M., Dikic, I., Bravo, J.
Deposit date:2006-10-02
Release date:2006-10-11
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Atypical Polyproline Recognition by the Cms N-Terminal SH3 Domain.
J.Biol.Chem., 281, 2006
2J7I
  • Download 2j7i
  • View 2j7i
Molmil generated image of 2j7i
ATYPICAL POLYPROLINE RECOGNITION BY THE CMS N-TERMINAL SH3 DOMAIN. CMS:CD2 HETERODIMER
Descriptor:CD2-ASSOCIATED PROTEIN, T-CELL SURFACE ANTIGEN CD2
Authors:Moncalian, G., Cardenes, N., Deribe, Y.L., Spinola-Amilibia, M., Dikic, I., Bravo, J.
Deposit date:2006-10-09
Release date:2006-11-06
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Atypical Polyproline Recognition by the Cms N-Terminal Src Homology 3 Domain.
J.Biol.Chem., 281, 2006
6H8O
  • Download 6h8o
  • View 6h8o
Molmil generated image of 6h8o
CRYSTAL STRUCTURE OF THE MASTER-REP PROTEIN NUCLEASE DOMAIN FROM THE FABA BEAN NECROTIC YELLOWS VIRUS
Descriptor:Replication-associated protein, SULFATE ION
Authors:Moncalian, G., Gonzalez-Montes, L.
Deposit date:2018-08-02
Release date:2018-08-22
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Crystal structure of the Master-Rep protein nuclease domain from the Faba Bean Necrotic Yellows Virus
To Be Published
4PCB
  • Download 4pcb
  • View 4pcb
Molmil generated image of 4pcb
CONJUGATIVE RELAXASE TRWC IN COMPLEX WITH MUTANT ORIT DNA
Descriptor:TrwC, DNA 5'-D(P*GP*CP*AP*CP*CP*GP*AP*AP*GP*GP*TP*GP*CP*GP*TP*AP*TP*TP*CP*TP*TP*GP - 3'), PHOSPHATE ION
Authors:Moncalian, G., Carballeira, J.D., de la Cruz, F., Gonzalez-Perez, B.
Deposit date:2014-04-14
Release date:2014-09-17
Last modified:2014-12-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A high security double lock and key mechanism in HUH relaxases controls oriT-processing for plasmid conjugation.
Nucleic Acids Res., 42, 2014
1GKI
  • Download 1gki
  • View 1gki
Molmil generated image of 1gki
PLASMID COUPLING PROTEIN TRWB IN COMPLEX WITH ADP AND MG2+.
Descriptor:CONJUGAL TRANSFER PROTEIN TRWB, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Gomis-Ruth, F.X., Moncalian, G., De La cruz, F., Coll, M.
Deposit date:2001-08-14
Release date:2002-05-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Bacterial Conjugation Protein Trwb Resembles Ring Helicases and F1-ATPase
Nature, 409, 2001
1GL6
  • Download 1gl6
  • View 1gl6
Molmil generated image of 1gl6
PLASMID COUPLING PROTEIN TRWB IN COMPLEX WITH THE NON-HYDROLYSABLE GTP ANALOGUE GDPNP
Descriptor:ATPASE, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, CHLORIDE ION, ...
Authors:Gomis-Ruth, F.X., Moncalian, G., De La cruz, F., Coll, M.
Deposit date:2001-08-28
Release date:2002-05-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Bacterial Conjugation Protein Trwb Resembles Ring Helicases and F1-ATPase
Nature, 409, 2001
1GL7
  • Download 1gl7
  • View 1gl7
Molmil generated image of 1gl7
PLASMID COUPLING PROTEIN TRWB IN COMPLEX WITH THE NON-HYDROLISABLE ATP-ANALOGUE ADPNP.
Descriptor:CONJUGAL TRANSFER PROTEIN TRWB, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, CHLORIDE ION
Authors:Gomis-Ruth, F.X., Moncalian, G., De La cruz, F., Coll, M.
Deposit date:2001-08-28
Release date:2002-05-16
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Bacterial Conjugation Protein Trwb Resembles Ring Helicases and F1-ATPase
Nature, 409, 2001
3DSC
  • Download 3dsc
  • View 3dsc
Molmil generated image of 3dsc
CRYSTAL STRUCTURE OF P. FURIOSUS MRE11 DNA SYNAPTIC COMPLEX
Descriptor:DNA double-strand break repair protein mre11, DNA (5'-D(P*DCP*DAP*DCP*DAP*DAP*DGP*DCP*DTP*DTP*DTP*DTP*DGP*DCP*DTP*DTP*DGP*DTP*DGP*DAP*DC)-3')
Authors:Williams, R.S., Moncalian, G., Shin, D.S., Tainer, J.A.
Deposit date:2008-07-11
Release date:2008-10-14
Last modified:2017-01-11
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Mre11 dimers coordinate DNA end bridging and nuclease processing in double-strand-break repair.
Cell(Cambridge,Mass.), 135, 2008
3QKR
  • Download 3qkr
  • View 3qkr
Molmil generated image of 3qkr
MRE11 RAD50 BINDING DOMAIN BOUND TO RAD50
Descriptor:DNA double-strand break repair rad50 ATPase, DNA double-strand break repair protein mre11, PHOSPHATE ION
Authors:Williams, G.J., Williams, R.S., Arvai, A., Moncalian, G., Tainer, J.A.
Deposit date:2011-02-01
Release date:2011-03-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:ABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair.
Nat.Struct.Mol.Biol., 18, 2011
3QKS
  • Download 3qks
  • View 3qks
Molmil generated image of 3qks
MRE11 RAD50 BINDING DOMAIN BOUND TO RAD50
Descriptor:DNA double-strand break repair rad50 ATPase, DNA double-strand break repair protein mre11
Authors:Williams, G.J., Williams, R.S., Arvai, A., Moncalian, G., Tainer, J.A.
Deposit date:2011-02-01
Release date:2011-03-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:ABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair.
Nat.Struct.Mol.Biol., 18, 2011
3QKT
  • Download 3qkt
  • View 3qkt
Molmil generated image of 3qkt
RAD50 ABC-ATPASE WITH ADJACENT COILED-COIL REGION IN COMPLEX WITH AMP-PNP
Descriptor:DNA double-strand break repair rad50 ATPase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION
Authors:Williams, G.J., Williams, R.S., Arvai, A., Moncalian, G., Tainer, J.A.
Deposit date:2011-02-01
Release date:2011-03-30
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:ABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair.
Nat.Struct.Mol.Biol., 18, 2011
3QKU
  • Download 3qku
  • View 3qku
Molmil generated image of 3qku
MRE11 RAD50 BINDING DOMAIN IN COMPLEX WITH RAD50 AND AMP-PNP
Descriptor:DNA double-strand break repair rad50 ATPase, DNA double-strand break repair protein mre11, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Williams, G.J., Williams, R.S., Arvai, A., Moncalian, G., Tainer, J.A.
Deposit date:2011-02-01
Release date:2011-03-30
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:ABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair.
Nat.Struct.Mol.Biol., 18, 2011
1OMH
  • Download 1omh
  • View 1omh
Molmil generated image of 1omh
CONJUGATIVE RELAXASE TRWC IN COMPLEX WITH ORIT DNA. METAL-FREE STRUCTURE.
Descriptor:DNA OLIGONUCLEOTIDE, trwC protein, SULFATE ION
Authors:Guasch, A., Lucas, M., Moncalian, G., Cabezas, M., Perez-Luque, R., Gomis-Ruth, F.X., de la Cruz, F., Coll, M.
Deposit date:2003-02-25
Release date:2003-11-25
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Recognition and processing of the origin of transfer DNA by conjugative relaxase TrwC.
Nat.Struct.Biol., 10, 2003
1OSB
  • Download 1osb
  • View 1osb
Molmil generated image of 1osb
CONJUGATIVE RELAXASE TRWC IN COMPLEX WITH ORIT DNA. METAL-FREE STRUCTURE.
Descriptor:Dna oligonucleotide, TrwC protein, SULFATE ION
Authors:Guasch, A., Lucas, M., Moncalian, G., Cabezas, M., Perez-Luque, R., Gomis-Ruth, F.X., de la Cruz, F., Coll, M.
Deposit date:2003-03-19
Release date:2003-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Recognition and processing of the origin of transfer DNA by conjugative relaxase TrwC.
Nat.Struct.Biol., 10, 2003
1E9R
  • Download 1e9r
  • View 1e9r
Molmil generated image of 1e9r
BACTERIAL CONJUGATIVE COUPLING PROTEIN TRWBDELTAN70. TRIGONAL FORM IN COMPLEX WITH SULPHATE.
Descriptor:CONJUGAL TRANSFER PROTEIN TRWB, SULFATE ION
Authors:Gomis-Rueth, F.X., Moncalian, G., Cabezon, E., de la Cruz, F., Coll, M.
Deposit date:2000-10-26
Release date:2001-02-06
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Bacterial Conjugation Protein Trwb Resembles Ring Helicases and F1-ATPase
Nature, 409, 2001
1E9S
  • Download 1e9s
  • View 1e9s
Molmil generated image of 1e9s
BACTERIAL CONJUGATIVE COUPLING PROTEIN TRWBDELTAN70. UNBOUND MONOCLINIC FORM.
Descriptor:CONJUGAL TRANSFER PROTEIN TRWB
Authors:Gomis-Rueth, F.X., Moncalian, G., Cabezon, E., de la Cruz, F., Coll, M.
Deposit date:2000-10-26
Release date:2001-02-06
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The Bacterial Conjugation Protein Trwb Resembles Ring Helicases and F1-ATPase
Nature, 409, 2001
1QX0
  • Download 1qx0
  • View 1qx0
Molmil generated image of 1qx0
CONJUGATIVE RELAXASE TRWC IN COMPLEX WITH ORIT DNA. METAL-BOUND STRUCTURE
Descriptor:DNA OLIGONUCLEOTIDE, trwC protein, SULFATE ION, ...
Authors:Guasch, A., Lucas, M., Moncalian, G., Cabezas, M., Prez-Luque, R., Gomis-Rth, F.X., de la Cruz, F., Coll, M.
Deposit date:2003-09-04
Release date:2003-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:RECOGNITION AND PROCESSING OF THE ORIGIN OF TRANSFER DNA BY CONJUGATIVE RELAXASE TRWC
Nat.Struct.Biol., 10, 2003
2AK5
  • Download 2ak5
  • View 2ak5
Molmil generated image of 2ak5
BETA PIX-SH3 COMPLEXED WITH A CBL-B PEPTIDE
Descriptor:Rho guanine nucleotide exchange factor 7, 8-residue peptide from a signal transduction protein CBL-B
Authors:Jozic, D., Cardenes, N., Deribe, Y.L., Moncalian, G., Hoeller, D., Groemping, Y., Dikic, I., Rittinger, K., Bravo, J.
Deposit date:2005-08-03
Release date:2005-10-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Cbl promotes clustering of endocytic adaptor proteins.
Nat.Struct.Mol.Biol., 12, 2005
2BZ8
  • Download 2bz8
  • View 2bz8
Molmil generated image of 2bz8
N-TERMINAL SH3 DOMAIN OF CIN85 BOUND TO CBL-B PEPTIDE
Descriptor:SH3-DOMAIN KINASE BINDING PROTEIN 1, SIGNAL TRANSDUCTION PROTEIN CBL-B SH3-BINDING PROTEIN CBL-B, RING FINGER PROTEIN 56, ...
Authors:Cardenes, N., Moncalian, G., Bravo, J.
Deposit date:2005-08-12
Release date:2005-10-05
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Cbl Promotes Clustering of Endocytic Adaptor Proteins
Nat.Struct.Mol.Biol., 12, 2005
3DSD
  • Download 3dsd
  • View 3dsd
Molmil generated image of 3dsd
CRYSTAL STRUCTURE OF P. FURIOSUS MRE11-H85S BOUND TO A BRANCHED DNA AND MANGANESE
Descriptor:DNA double-strand break repair protein mre11, DNA (5'-D(*DCP*DGP*DCP*DGP*DCP*DAP*DCP*DAP*DAP*DGP*DCP*DTP*DTP*DTP*DTP*DGP*DCP*DTP*DTP*DGP*DTP*DGP*DGP*DAP*DTP*DA)-3'), MANGANESE (II) ION
Authors:Williams, R.S., Moiani, D., Tainer, J.A.
Deposit date:2008-07-11
Release date:2008-10-14
Last modified:2017-01-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Mre11 dimers coordinate DNA end bridging and nuclease processing in double-strand-break repair.
Cell(Cambridge,Mass.), 135, 2008
1L8D
  • Download 1l8d
  • View 1l8d
Molmil generated image of 1l8d
RAD50 COILED-COIL ZN HOOK
Descriptor:DNA double-strand break repair rad50 ATPase, MERCURY (II) ION, PHOSPHATE ION, ...
Authors:Hopfner, K.P., Tainer, J.A.
Deposit date:2002-03-20
Release date:2002-08-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair.
Nature, 418, 2002
1S6M
  • Download 1s6m
  • View 1s6m
Molmil generated image of 1s6m
CONJUGATIVE RELAXASE TRWC IN COMPLEX WITH ORIT DNA. METAL-BOUND STRUCTURE
Descriptor:DNA (25-MER), TrwC, NICKEL (II) ION
Authors:Guasch, A., Lucas, M., Moncalian, G., Cabezas, M., Perez-Luque, R., Gomis-Ruth, F.X., de la Cruz, F., Coll, M.
Deposit date:2004-01-26
Release date:2005-06-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Unveiling the molecular mechanism of a conjugative relaxase: The structure of TrwC complexed with a 27-mer DNA comprising the recognition hairpin and the cleavage site.
J.Mol.Biol., 358, 2006
<12>