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1KIV
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RECOMBINANT KRINGLE IV-10/M66 VARIANT OF HUMAN APOLIPOPROTEIN(A)
Descriptor:APOLIPOPROTEIN A
Authors:Mochalkin, I., Tulinsky, A., Scanu, A.
Deposit date:1998-08-26
Release date:1999-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Recombinant kringle IV-10 modules of human apolipoprotein(a): structure, ligand binding modes, and biological relevance.
Biochemistry, 38, 1999
2C00
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM PSEUDOMONAS AERUGINOSA IN APO FORM
Descriptor:BIOTIN CARBOXYLASE, SULFATE ION
Authors:Mochalkin, I.
Deposit date:2008-03-21
Release date:2008-09-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Evidence for Substrate-Induced Synergism and Half-Sites Reactivity in Biotin Carboxylase.
Protein Sci., 17, 2008
2J9G
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E. COLI IN COMPLEX WITH AMPPNP AND ADP
Descriptor:BIOTIN CARBOXYLASE, MAGNESIUM ION, SULFATE ION, ...
Authors:Mochalkin, I.
Deposit date:2008-03-21
Release date:2008-09-09
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural Evidence for Substrate-Induced Synergism and Half-Sites Reactivity in Biotin Carboxylase.
Protein Sci., 17, 2008
2V0H
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CHARACTERIZATION OF SUBSTRATE BINDING AND CATALYSIS OF THE POTENTIAL ANTIBACTERIAL TARGET N-ACETYLGLUCOSAMINE-1-PHOSPHATE URIDYLTRANSFERASE (GLMU)
Descriptor:BIFUNCTIONAL PROTEIN GLMU, DI(HYDROXYETHYL)ETHER, SULFATE ION, ...
Authors:Mochalkin, I., Lightle, S., Ohren, J.F., Chirgadze, N.Y.
Deposit date:2007-05-14
Release date:2008-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Characterization of Substrate Binding and Catalysis in the Potential Antibacterial Target N-Acetylglucosamine-1-Phosphate Uridyltransferase (Glmu).
Protein Sci., 16, 2007
2V0I
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CHARACTERIZATION OF SUBSTRATE BINDING AND CATALYSIS OF THE POTENTIAL ANTIBACTERIAL TARGET N-ACETYLGLUCOSAMINE-1-PHOSPHATE URIDYLTRANSFERASE (GLMU)
Descriptor:BIFUNCTIONAL PROTEIN GLMU, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE, TETRAETHYLENE GLYCOL, ...
Authors:Mochalkin, I., Lightle, S., Ohren, J.F., Chirgadze, N.Y.
Deposit date:2007-05-14
Release date:2008-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Characterization of Substrate Binding and Catalysis in the Potential Antibacterial Target N-Acetylglucosamine-1-Phosphate Uridyltransferase (Glmu).
Protein Sci., 16, 2007
2V0J
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CHARACTERIZATION OF SUBSTRATE BINDING AND CATALYSIS OF THE POTENTIAL ANTIBACTERIAL TARGET N-ACETYLGLUCOSAMINE-1-PHOSPHATE URIDYLTRANSFERASE (GLMU)
Descriptor:BIFUNCTIONAL PROTEIN GLMU, 5,6-DIHYDROURIDINE-5'-MONOPHOSPHATE, MAGNESIUM ION, ...
Authors:Mochalkin, I., Lightle, S., Ohren, J.F., Chirgadze, N.Y.
Deposit date:2007-05-14
Release date:2008-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Characterization of Substrate Binding and Catalysis in the Potential Antibacterial Target N-Acetylglucosamine-1-Phosphate Uridyltransferase (Glmu).
Protein Sci., 16, 2007
2V0K
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CHARACTERIZATION OF SUBSTRATE BINDING AND CATALYSIS OF THE POTENTIAL ANTIBACTERIAL TARGET N-ACETYLGLUCOSAMINE-1-PHOSPHATE URIDYLTRANSFERASE (GLMU)
Descriptor:BIFUNCTIONAL PROTEIN GLMU, URIDINE-5'-DIPHOSPHATE, TETRAETHYLENE GLYCOL, ...
Authors:Mochalkin, I., Lightle, S., Ohren, J.F., Chirgadze, N.Y.
Deposit date:2007-05-14
Release date:2008-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Characterization of Substrate Binding and Catalysis in the Potential Antibacterial Target N-Acetylglucosamine-1-Phosphate Uridyltransferase (Glmu).
Protein Sci., 16, 2007
2V0L
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CHARACTERIZATION OF SUBSTRATE BINDING AND CATALYSIS OF THE POTENTIAL ANTIBACTERIAL TARGET N-ACETYLGLUCOSAMINE-1-PHOSPHATE URIDYLTRANSFERASE (GLMU)
Descriptor:BIFUNCTIONAL PROTEIN GLMU, URIDINE, TETRAETHYLENE GLYCOL, ...
Authors:Mochalkin, I., Lightle, S., Ohren, J.F., Chirgadze, N.Y.
Deposit date:2007-05-14
Release date:2008-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Characterization of Substrate Binding and Catalysis in the Potential Antibacterial Target N-Acetylglucosamine-1-Phosphate Uridyltransferase (Glmu).
Protein Sci., 16, 2007
2VD4
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STRUCTURE OF SMALL-MOLECULE INHIBITOR OF GLMU FROM HAEMOPHILUS INFLUENZAE REVEALS AN ALLOSTERIC BINDING SITE
Descriptor:BIFUNCTIONAL PROTEIN GLMU, 4-chloro-N-(3-methoxypropyl)-N-[(3S)-1-(2-phenylethyl)piperidin-3-yl]benzamide, SULFATE ION, ...
Authors:Mochalkin, I., Lightle, S., McDowell, L.
Deposit date:2007-09-28
Release date:2008-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of a Small-Molecule Inhibitor Complexed with Glmu from Haemophilus Influenzae Reveals an Allosteric Binding Site.
Protein Sci., 17, 2008
2VES
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CRYSTAL STRUCTURE OF LPXC FROM PSEUDOMONAS AERUGINOSA COMPLEXED WITH THE POTENT BB-78485 INHIBITOR
Descriptor:UDP-3-O-acyl-N-acetylglucosamine deacetylase, ZINC ION, (2R)-N-hydroxy-3-naphthalen-2-yl-2-[(naphthalen-2-ylsulfonyl)amino]propanamide, ...
Authors:Mochalkin, I., Knafels, J.D.
Deposit date:2007-10-26
Release date:2008-01-15
Last modified:2018-09-19
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of LpxC from Pseudomonas aeruginosa complexed with the potent BB-78485 inhibitor.
Protein Sci., 17, 2008
2VPQ
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM S. AUREUS COMPLEXED WITH AMPPNP
Descriptor:ACETYL-COA CARBOXYLASE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ...
Authors:Mochalkin, I.
Deposit date:2008-03-03
Release date:2008-09-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Evidence for Substrate-Induced Synergism and Half-Sites Reactivity in Biotin Carboxylase.
Protein Sci., 17, 2008
2VQD
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM PSEUDOMONAS AERUGINOSA COMPLEXED WITH AMPCP
Descriptor:BIOTIN CARBOXYLASE, PHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, MAGNESIUM ION, ...
Authors:Mochalkin, I.
Deposit date:2008-03-13
Release date:2008-09-09
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Structural Evidence for Substrate-Induced Synergism and Half-Sites Reactivity in Biotin Carboxylase.
Protein Sci., 17, 2008
2VR1
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E. COLI IN COMPLEX WITH ATP ANALOG, ADPCF2P.
Descriptor:BIOTIN CARBOXYLASE, CHLORIDE ION, PHOSPHODIFLUOROMETHYLPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Mochalkin, I., Waldrop, G.L.
Deposit date:2008-03-24
Release date:2008-09-09
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Evidence for Substrate-Induced Synergism and Half-Sites Reactivity in Biotin Carboxylase.
Protein Sci., 17, 2008
2W6M
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E. COLI IN COMPLEX WITH AMINO-OXAZOLE FRAGMENT SERIES
Descriptor:BIOTIN CARBOXYLASE, (2-AMINO-1,3-OXAZOL-5-YL)-(3-BROMOPHENYL)METHANONE, CHLORIDE ION
Authors:Mochalkin, I., Miller, J.R.
Deposit date:2008-12-18
Release date:2009-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches.
Acs Chem.Biol., 4, 2009
2W6N
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E. COLI IN COMPLEX WITH AMINO-OXAZOLE FRAGMENT SERIES
Descriptor:BIOTIN CARBOXYLASE, 2-AMINO-N,N-BIS(PHENYLMETHYL)-1,3-OXAZOLE-5-CARBOXAMIDE, CHLORIDE ION
Authors:Mochalkin, I., Miller, J.R.
Deposit date:2008-12-18
Release date:2009-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches.
Acs Chem.Biol., 4, 2009
2W6O
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E. COLI IN COMPLEX WITH 4-AMINO-7,7-DIMETHYL-7,8-DIHYDRO-QUINAZOLINONE FRAGMENT
Descriptor:BIOTIN CARBOXYLASE, 4-amino-7,7-dimethyl-7,8-dihydroquinazolin-5(6H)-one, CHLORIDE ION
Authors:Mochalkin, I., Miller, J.R.
Deposit date:2008-12-18
Release date:2009-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches.
Acs Chem.Biol., 4, 2009
2W6P
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E. COLI IN COMPLEX WITH 5-METHYL-6-PHENYL-QUINAZOLINE-2,4-DIAMINE
Descriptor:ACETYL-COA CARBOXYLASE, 5-methyl-6-phenylquinazoline-2,4-diamine
Authors:Mochalkin, I., Miller, J.R.
Deposit date:2008-12-18
Release date:2009-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches.
Acs Chem.Biol., 4, 2009
2W6Q
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E. COLI IN COMPLEX WITH THE TRIAZINE-2,4-DIAMINE FRAGMENT
Descriptor:BIOTIN CARBOXYLASE, 6-(2-phenoxyethoxy)-1,3,5-triazine-2,4-diamine, CHLORIDE ION
Authors:Mochalkin, I., Miller, J.R.
Deposit date:2008-12-18
Release date:2009-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches.
Acs Chem.Biol., 4, 2009
2W6Z
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E. COLI IN COMPLEX WITH THE 3-(3-METHYL-BUT-2-ENYL)-3H-PURIN-6-YLAMINE FRAGMENT
Descriptor:BIOTIN CARBOXYLASE, 3-(3-methylbut-2-en-1-yl)-3H-purin-6-amine, CHLORIDE ION
Authors:Mochalkin, I., Miller, J.R.
Deposit date:2008-12-19
Release date:2009-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches.
Acs Chem.Biol., 4, 2009
2W70
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E. COLI IN COMPLEX WITH THE AMINO-THIAZOLE-PYRIMIDINE FRAGMENT
Descriptor:BIOTIN CARBOXYLASE, 4-(2-amino-1,3-thiazol-4-yl)pyrimidin-2-amine, CHLORIDE ION
Authors:Mochalkin, I., Miller, J.R.
Deposit date:2008-12-19
Release date:2009-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches.
Acs Chem.Biol., 4, 2009
2W71
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E. COLI IN COMPLEX WITH THE IMIDAZOLE-PYRIMIDINE INHIBITOR
Descriptor:BIOTIN CARBOXYLASE, CHLORIDE ION, 4-[1-(2,6-dichlorobenzyl)-2-methyl-1H-imidazol-4-yl]pyrimidin-2-amine
Authors:Mochalkin, I., Miller, J.R.
Deposit date:2008-12-19
Release date:2009-05-19
Last modified:2014-11-19
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches.
Acs Chem.Biol., 4, 2009
3KIV
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RECOMBINANT KRINGLE IV-10/M66 VARIANT OF HUMAN APOLIPOPROTEIN(A)
Descriptor:APOLIPOPROTEIN, 6-AMINOHEXANOIC ACID
Authors:Mochalkin, I., Tulinsky, A., Scanu, A.
Deposit date:1998-09-08
Release date:1999-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Recombinant kringle IV-10 modules of human apolipoprotein(a): structure, ligand binding modes, and biological relevance.
Biochemistry, 38, 1999
4KIV
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RECOMBINANT KRINGLE IV-10/W72R MUTANT OF HUMAN APOLIPOPROTEIN(A)
Descriptor:APOLIPOPROTEIN
Authors:Mochalkin, I., Tulinsky, A., Scanu, A.
Deposit date:1998-08-26
Release date:1999-05-18
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Recombinant kringle IV-10 modules of human apolipoprotein(a): structure, ligand binding modes, and biological relevance.
Biochemistry, 38, 1999
7KME
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CRYSTAL STRUCTURE OF HUMAN ALPHA-THROMBIN INHIBITED WITH SEL2711.
Descriptor:THROMBIN L-CHAIN, THROMBIN H-CHAIN, HIRUGEN, ...
Authors:Mochalkin, I., Tulinsky, A.
Deposit date:1999-02-26
Release date:1999-03-09
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of thrombin retro-inhibited with SEL2711 and SEL2770 as they relate to factor Xa binding.
Acta Crystallogr.,Sect.D, 55, 1999
8KME
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CRYSTAL STRUCTURE OF HUMAN ALPHA-THROMBIN INHIBITED WITH SEL2770.
Descriptor:THROMBIN, N-ACETYLHIRUDIN, SEL2770, ...
Authors:Mochalkin, I., Tulinsky, A.
Deposit date:1999-03-21
Release date:1999-03-24
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of thrombin retro-inhibited with SEL2711 and SEL2770 as they relate to factor Xa binding.
Acta Crystallogr.,Sect.D, 55, 1999
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