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3AK8
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CRYSTAL STRUCTURE OF THE SEP22 DODECAMER, A DPS-LIKE PROTEIN FROM SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR ENTERITIDIS
Descriptor:DNA protection during starvation protein, SULFATE ION, MAGNESIUM ION
Authors:Miyamoto, T., Asahina, Y., Miyazaki, S., Shimizu, H., Ohto, U., Noguchi, S., Satow, Y.
Deposit date:2010-07-08
Release date:2011-01-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Structures of the SEp22 dodecamer, a Dps-like protein from Salmonella enterica subsp. enterica serovar Enteritidis
Acta Crystallogr.,Sect.F, 67, 2011
3AK9
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CRYSTAL STRUCTURE OF THE SEP22 DODECAMER, A DPS-LIKE PROTEIN FROM SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR ENTERITIDIS, FE-SOAKED FORM
Descriptor:DNA protection during starvation protein, FE (II) ION, SULFATE ION, ...
Authors:Miyamoto, T., Asahina, Y., Miyazaki, S., Shimizu, H., Ohto, U., Noguchi, S., Satow, Y.
Deposit date:2010-07-08
Release date:2011-01-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structures of the SEp22 dodecamer, a Dps-like protein from Salmonella enterica subsp. enterica serovar Enteritidis
Acta Crystallogr.,Sect.F, 67, 2011
6AHS
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MOUSE KALLIKREIN 7 IN COMPLEX WITH IMIDAZOLINYLINDOLE DERIVATIVE
Descriptor:Kallikrein-7, 1-[(2-chlorophenyl)sulfonyl]-5-methyl-3-[(4R)-2-methyl-4,5-dihydro-1H-imidazol-4-yl]-1H-indole, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Sugawara, H.
Deposit date:2018-08-20
Release date:2019-01-02
Last modified:2019-01-23
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Discovery and structure-activity relationship of imidazolinylindole derivatives as kallikrein 7 inhibitors.
Bioorg. Med. Chem. Lett., 29, 2019
3VYD
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HUMAN RENIN IN COMPLEX WITH INHIBITOR 6
Descriptor:Renin, N-ACETYL-D-GLUCOSAMINE, (3S,5R)-5-{[4-(2-chlorophenyl)-2,2-dimethyl-5-oxopiperazin-1-yl]methyl}-N-(3-methylbutyl)piperidine-3-carboxamide
Authors:Takahashi, M., Hanzawa, H.
Deposit date:2012-09-24
Release date:2012-12-19
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Design and discovery of new (3S,5R)-5-[4-(2-chlorophenyl)-2,2-dimethyl-5-oxopiperazin-1-yl]piperidine-3-carboxamides as potent renin inhibitors
Bioorg.Med.Chem.Lett., 22, 2012
3VYE
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HUMAN RENIN IN COMPLEX WITH INHIBITOR 7
Descriptor:Renin, N-ACETYL-D-GLUCOSAMINE, (3S,5R)-5-[4-(2-chlorophenyl)-2,2-dimethyl-5-oxopiperazin-1-yl]-N-(3-methylbutyl)piperidine-3-carboxamide
Authors:Takahashi, M., Matsui, Y., Hanzawa, H.
Deposit date:2012-09-24
Release date:2012-12-19
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Design and discovery of new (3S,5R)-5-[4-(2-chlorophenyl)-2,2-dimethyl-5-oxopiperazin-1-yl]piperidine-3-carboxamides as potent renin inhibitors
Bioorg.Med.Chem.Lett., 22, 2012
3VYF
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HUMAN RENIN IN COMPLEX WITH INHIBITOR 9
Descriptor:Renin, N-ACETYL-D-GLUCOSAMINE, (3S,5R)-5-[4-(2-chlorophenyl)-2,2-dimethyl-5-oxopiperazin-1-yl]-N-(2,6-dimethylheptan-4-yl)piperidine-3-carboxamide
Authors:Takahashi, M., Hanzawa, H.
Deposit date:2012-09-24
Release date:2012-12-19
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Design and discovery of new (3S,5R)-5-[4-(2-chlorophenyl)-2,2-dimethyl-5-oxopiperazin-1-yl]piperidine-3-carboxamides as potent renin inhibitors
Bioorg.Med.Chem.Lett., 22, 2012
3GO5
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CRYSTAL STRUCTURE OF A MULTIDOMAIN PROTEIN WITH NUCLEIC ACID BINDING DOMAINS (SP_0946) FROM STREPTOCOCCUS PNEUMONIAE TIGR4 AT 1.40 A RESOLUTION
Descriptor:Multidomain protein with S1 RNA-binding domains, CHLORIDE ION, 1,2-ETHANEDIOL
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2009-03-18
Release date:2009-04-07
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure of a virulence regulatory factor CvfB reveals a novel winged helix RNA binding module.
Structure, 18, 2010
3VSW
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HUMAN RENIN IN COMPLEX WITH COMPOUND 8
Descriptor:Renin, N-ACETYL-D-GLUCOSAMINE, (2S,4S,5S)-5-amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-4-hydroxy-6-{4-[2-(3-methoxypropoxy)phenyl]-3-oxopiperazin-1-yl}-2-(propan-2-yl)hexanamide
Authors:Takahashi, M., Hanzawa, H.
Deposit date:2012-05-11
Release date:2012-07-25
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:Design and optimization of novel (2S,4S,5S)-5-amino-6-(2,2-dimethyl-5-oxo-4-phenylpiperazin-1-yl)-4-hydroxy-2-isopropylhexanamides as renin inhibitors
Bioorg.Med.Chem.Lett., 22, 2012
3VSX
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HUMAN RENIN IN COMPLEX WITH COMPOUND 18
Descriptor:Renin, N-ACETYL-D-GLUCOSAMINE, (2S,4S,5S)-5-amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-6-[4-(2-chlorophenyl)-2,2-dimethyl-5-oxopiperazin-1-yl]-4-hydroxy-2-(propan-2-yl)hexanamide
Authors:Takahashi, M., Hanzawa, H.
Deposit date:2012-05-11
Release date:2012-07-25
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Design and optimization of novel (2S,4S,5S)-5-amino-6-(2,2-dimethyl-5-oxo-4-phenylpiperazin-1-yl)-4-hydroxy-2-isopropylhexanamides as renin inhibitors
Bioorg.Med.Chem.Lett., 22, 2012
3VUC
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HUMAN RENIN IN COMPLEX WITH COMPOUND 5
Descriptor:Renin, N-ACETYL-D-GLUCOSAMINE, (2R,4S,5S)-5-amino-6-[4-(2-chlorophenyl)-2,2-dimethyl-5-oxopiperazin-1-yl]-2-ethyl-4-hydroxy-N-[(1R,2S,3S,5S,7S)-5-hydroxytricyclo[3.3.1.1~3,7~]dec-2-yl]hexanamide
Authors:Takahashi, M., Matsui, Y., Hanzawa, H.
Deposit date:2012-06-26
Release date:2013-05-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Discovery of DS-8108b, a Novel Orally Bioavailable Renin Inhibitor
ACS MED.CHEM.LETT., 3, 2012