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2QDJ
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CRYSTAL STRUCTURE OF THE RETINOBLASTOMA PROTEIN N-DOMAIN PROVIDES INSIGHT INTO TUMOR SUPPRESSION, LIGAND INTERACTION AND HOLOPROTEIN ARCHITECTURE
Descriptor:Retinoblastoma-associated protein
Authors:Hassler, M., Mittnacht, S., Pearl, L.H.
Deposit date:2007-06-21
Release date:2008-01-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the retinoblastoma protein N domain provides insight into tumor suppression, ligand interaction, and holoprotein architecture.
Mol.Cell, 28, 2007
1O9K
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CRYSTAL STRUCTURE OF THE RETINOBLASTOMA TUMOUR SUPPRESSOR PROTEIN BOUND TO E2F PEPTIDE
Descriptor:RETINOBLASTOMA-ASSOCIATED PROTEIN, TRANSCRIPTION FACTOR E2F1
Authors:Xiao, B., Spencer, J., Clements, A., Ali-Khan, N., Mittnacht, S., Broceno, C., Burghammer, M., Perrakis, A., Marmorstein, R., Gamblin, S.J.
Deposit date:2002-12-16
Release date:2003-03-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of the Retinoblastoma Tumor Suppressor Protein Bound to E2F and the Molecular Basis of its Regulation
Proc.Natl.Acad.Sci.USA, 100, 2003
2CN5
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CRYSTAL STRUCTURE OF HUMAN CHK2 IN COMPLEX WITH ADP
Descriptor:SERINE/THREONINE-PROTEIN KINASE CHK2, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Oliver, A.W., Pearl, L.H.
Deposit date:2006-05-18
Release date:2006-06-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Trans-Activation of the DNA-Damage Signalling Protein Kinase Chk2 by T-Loop Exchange
Embo J., 25, 2006
2CN8
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CRYSTAL STRUCTURE OF HUMAN CHK2 IN COMPLEX WITH DEBROMOHYMENIALDISINE
Descriptor:SERINE/THREONINE-PROTEIN KINASE CHK2, MAGNESIUM ION, NITRATE ION, ...
Authors:Oliver, A.W., Pearl, L.H.
Deposit date:2006-05-18
Release date:2006-06-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Trans-Activation of the DNA-Damage Signalling Protein Kinase Chk2 by T-Loop Exchange
Embo J., 25, 2006