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1KSO
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BU of 1kso by Molmil
CRYSTAL STRUCTURE OF APO S100A3
Descriptor: S100 CALCIUM-BINDING PROTEIN A3
Authors:Mittl, P.R, Fritz, G, Sargent, D.F, Richmond, T.J, Heizmann, C.W, Grutter, M.G.
Deposit date:2002-01-14
Release date:2002-07-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Metal-free MIRAS phasing: structure of apo-S100A3.
Acta Crystallogr.,Sect.D, 58, 2002
1OUV
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BU of 1ouv by Molmil
Helicobacter cysteine rich protein C (HcpC)
Descriptor: conserved hypothetical secreted protein
Authors:Mittl, P.R, Luethy, L.
Deposit date:2003-03-25
Release date:2004-03-30
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Crystal Structure of Helicobacter Cysteine-rich Protein C at 2.0A Resolution: Similar Peptide-binding Sites in TPR and SEL1-like Repeat Proteins
J.Mol.Biol., 340, 2004
4PLQ
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BU of 4plq by Molmil
Crystal Structures of Designed Armadillo Repeat Proteins: Implications of Construct Design and Crystallization Conditions on Overall Structure.
Descriptor: Arm00011
Authors:Mittl, P.R, Reichen, C, Madhurantakam, C, Pluckthun, A.
Deposit date:2014-05-19
Release date:2014-08-27
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of designed armadillo repeat proteins: Implications of construct design and crystallization conditions on overall structure.
Protein Sci., 23, 2014
6F5E
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BU of 6f5e by Molmil
Crystal structure of DARPin-DARPin rigid fusion, variant DD_D12_10_47 in complex JNK1a1 and JIP1 peptide
Descriptor: C-Jun-amino-terminal kinase-interacting protein 1, DD_D12_10_47, Mitogen-activated protein kinase 8
Authors:Wu, Y, Mittl, P.R, Honegger, A, Batyuk, A, Plueckthun, A.
Deposit date:2017-12-01
Release date:2017-12-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of DARPin-DARPin rigid fusion, variant DD_D12_10_47 in complex JNK1a1 and JIP1 peptide
To be published
2FBE
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BU of 2fbe by Molmil
Crystal Structure of the PRYSPRY-domain
Descriptor: PREDICTED: similar to ret finger protein-like 1
Authors:Gruetter, C, Briand, C, Capitani, G, Mittl, P.R, Gruetter, M.G.
Deposit date:2005-12-09
Release date:2006-01-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Structure of the PRYSPRY-domain: Implications for autoinflammatory diseases
Febs Lett., 580, 2006
4PLS
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BU of 4pls by Molmil
Crystal Structures of Designed Armadillo Repeat Proteins: Implications of Construct Design and Crystallization Conditions on Overall Structure.
Descriptor: ACETATE ION, Arm00010, CALCIUM ION
Authors:Reichen, C, Madhurantakam, C, Plueckthun, A, Mittl, P.R.
Deposit date:2014-05-19
Release date:2014-12-10
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal Structures of Designed Armadillo Repeat Proteins: Implications of Construct Design and Crystallization Conditions on Overall Structure.
Protein Sci., 23, 2014
2WL1
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BU of 2wl1 by Molmil
Pyrin PrySpry domain
Descriptor: 1,2-ETHANEDIOL, PYRIN, THIOCYANATE ION
Authors:Weinert, C, Mittl, P.R, Gruetter, M.G.
Deposit date:2009-06-19
Release date:2009-10-20
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:The Crystal Structure of Human Pyrin B30.2 Domain: Implications for Mutations Associated with Familial Mediterranean Fever.
J.Mol.Biol., 394, 2009
2XYH
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BU of 2xyh by Molmil
Caspase-3:CAS60254719
Descriptor: 5-CHLORO-4-OXOPENTANOIC ACID, CASPASE-3 SUBUNIT P12, CASPASE-3 SUBUNIT P17
Authors:Ganesan, R, Jelakovic, S, Grutter, M.G, Mittl, P.R.
Deposit date:2010-11-17
Release date:2011-08-17
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:In Silico Identification and Crystal Structure Validation of Caspase-3 Inhibitors without a P1 Aspartic Acid Moiety.
Acta Crystallogr.,Sect.F, 67, 2011
2XYP
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BU of 2xyp by Molmil
Caspase-3:CAS26049945
Descriptor: CASPASE-3 SUBUNIT P12, CASPASE-3 SUBUNIT P17, PHENYLMETHYL N-[(2S)-4-CHLORO-3-OXO-1-PHENYL-BUTAN-2-YL]CARBAMATE
Authors:Ganesan, R, Jelakovic, S, Grutter, M.G, Mittl, P.R.
Deposit date:2010-11-18
Release date:2011-08-17
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:In Silico Identification and Crystal Structure Validation of Caspase-3 Inhibitors without a P1 Aspartic Acid Moiety.
Acta Crystallogr.,Sect.F, 67, 2011
2XYG
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BU of 2xyg by Molmil
Caspase-3:CAS329306
Descriptor: CASPASE-3 SUBUNIT P12, CASPASE-3 SUBUNIT P17, N-[(2S)-4-chloro-3-oxo-1-phenyl-butan-2-yl]-4-methyl-benzenesulfonamide
Authors:Ganesan, R, Jelakovic, S, Grutter, M.G, Mittl, P.R.
Deposit date:2010-11-17
Release date:2011-08-17
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:In Silico Identification and Crystal Structure Validation of Caspase-3 Inhibitors without a P1 Aspartic Acid Moiety.
Acta Crystallogr.,Sect.F, 67, 2011
3ZUV
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BU of 3zuv by Molmil
Crystal structure of a designed selected Ankyrin Repeat protein in complex with the phosphorylated MAP kinase ERK2
Descriptor: DESIGNED ANKYRIN REPEAT PROTEIN, MITOGEN-ACTIVATED PROTEIN KINASE 1, SULFATE ION
Authors:Kummer, L, Mittl, P.R, Pluckthun, A.
Deposit date:2011-07-20
Release date:2012-06-27
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Structural and Functional Analysis of Phosphorylation-Specific Binders of the Kinase Erk from Designed Ankyrin Repeat Protein Libraries.
Proc.Natl.Acad.Sci.USA, 109, 2012
3ZU7
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BU of 3zu7 by Molmil
Crystal structure of a designed selected Ankyrin Repeat protein in complex with the MAP kinase ERK2
Descriptor: DESIGNED ANKYRIN REPEAT PROTEIN, MITOGEN-ACTIVATED PROTEIN KINASE 1
Authors:Kummer, L, Mittl, P.R, Pluckthun, A.
Deposit date:2011-07-16
Release date:2012-06-27
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structural and Functional Analysis of Phosphorylation-Specific Binders of the Kinase Erk from Designed Ankyrin Repeat Protein Libraries.
Proc.Natl.Acad.Sci.USA, 109, 2012
1AIE
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BU of 1aie by Molmil
P53 TETRAMERIZATION DOMAIN CRYSTAL STRUCTURE
Descriptor: P53
Authors:Mittl, P.R.E, Chene, P, Gruetter, M.G.
Deposit date:1997-04-17
Release date:1997-06-16
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystallization and structure solution of p53 (residues 326-356) by molecular replacement using an NMR model as template.
Acta Crystallogr.,Sect.D, 54, 1998
1C94
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BU of 1c94 by Molmil
REVERSING THE SEQUENCE OF THE GCN4 LEUCINE ZIPPER DOES NOT AFFECT ITS FOLD.
Descriptor: RETRO-GCN4 LEUCINE ZIPPER
Authors:Mittl, P.R.E, Deillon, C.A, Sargent, D, Liu, N, Klauser, S, Thomas, R.M, Gutte, B, Gruetter, M.G.
Deposit date:1999-07-30
Release date:2000-03-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:The retro-GCN4 leucine zipper sequence forms a stable three-dimensional structure.
Proc.Natl.Acad.Sci.USA, 97, 2000
1TGK
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BU of 1tgk by Molmil
HUMAN TRANSFORMING GROWTH FACTOR BETA 3, CRYSTALLIZED FROM PEG 4000
Descriptor: TRANSFORMING GROWTH FACTOR BETA 3
Authors:Mittl, P.R.E, Priestle, J.P, Gruetter, M.G.
Deposit date:1996-07-10
Release date:1997-03-12
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The crystal structure of TGF-beta 3 and comparison to TGF-beta 2: implications for receptor binding.
Protein Sci., 5, 1996
1TGJ
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BU of 1tgj by Molmil
HUMAN TRANSFORMING GROWTH FACTOR-BETA 3, CRYSTALLIZED FROM DIOXANE
Descriptor: 1,4-DIETHYLENE DIOXIDE, TRANSFORMING GROWTH FACTOR-BETA 3
Authors:Mittl, P.R.E, Priestle, J.P, Gruetter, M.G.
Deposit date:1996-07-09
Release date:1997-01-11
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of TGF-beta 3 and comparison to TGF-beta 2: implications for receptor binding.
Protein Sci., 5, 1996
1HIA
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BU of 1hia by Molmil
KALLIKREIN COMPLEXED WITH HIRUSTASIN
Descriptor: HIRUSTASIN, KALLIKREIN
Authors:Mittl, P, Di Marco, S, Gruetter, M.
Deposit date:1996-12-12
Release date:1997-12-24
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A new structural class of serine protease inhibitors revealed by the structure of the hirustasin-kallikrein complex.
Structure, 5, 1997
7Z7C
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BU of 7z7c by Molmil
Broadly neutralizing DARPin bnD.8 in complex with the HIV-1 envelope variable loop 3 peptide V3 (BF520)
Descriptor: 1,2-ETHANEDIOL, Broadly neutralizing DARPin bnD.8, Envelope glycoprotein gp160, ...
Authors:Mittl, P.R, Gloegl, M.
Deposit date:2022-03-15
Release date:2023-03-29
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.22 Å)
Cite:Trapping the HIV-1 V3 loop in a helical conformation enables broad neutralization.
Nat.Struct.Mol.Biol., 30, 2023
1GES
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BU of 1ges by Molmil
ANATOMY OF AN ENGINEERED NAD-BINDING SITE
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLUTATHIONE REDUCTASE
Authors:Mittl, P.R.E, Schulz, G.E.
Deposit date:1994-01-18
Release date:1994-11-01
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Anatomy of an engineered NAD-binding site.
Protein Sci., 3, 1994
1GEU
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BU of 1geu by Molmil
ANATOMY OF AN ENGINEERED NAD-BINDING SITE
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLUTATHIONE REDUCTASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Mittl, P.R.E, Schulz, G.E.
Deposit date:1994-01-18
Release date:1994-11-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Anatomy of an engineered NAD-binding site.
Protein Sci., 3, 1994
1GET
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BU of 1get by Molmil
ANATOMY OF AN ENGINEERED NAD-BINDING SITE
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLUTATHIONE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Mittl, P.R.E, Schulz, G.E.
Deposit date:1994-01-18
Release date:1994-11-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Anatomy of an engineered NAD-binding site.
Protein Sci., 3, 1994
7TAL
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BU of 7tal by Molmil
LOV2-DARPIN fusion : D4_deltaDARP
Descriptor: D4_deltaDARP LOV2-DARPin fusion, FLAVIN MONONUCLEOTIDE, MAGNESIUM ION
Authors:Mittl, P.
Deposit date:2021-12-21
Release date:2023-07-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:LOV2-DARPIN fusion : D4_deltaDARP
To Be Published
7TBN
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BU of 7tbn by Molmil
LOV2-DARPIN fusion : D11
Descriptor: CARBONATE ION, D11 LOV2-DARPin fusion, GLYCEROL
Authors:Mittl, P.
Deposit date:2021-12-22
Release date:2023-07-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:LOV2-DARPIN fusion : D11
To Be Published
7TBO
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BU of 7tbo by Molmil
LOV2-DARPIN fusion : D12
Descriptor: D12 LOV2-DARPin fusion, GLYCEROL
Authors:Mittl, P.
Deposit date:2021-12-22
Release date:2023-07-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:LOV2-DARPIN fusion : D12
To Be Published
7TBQ
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BU of 7tbq by Molmil
LOV2-DARPIN fusion : D7
Descriptor: CHLORIDE ION, D7 LOV2-DARPin fusion, FLAVIN MONONUCLEOTIDE, ...
Authors:Mittl, P.
Deposit date:2021-12-22
Release date:2023-07-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.678 Å)
Cite:LOV2-DARPIN fusion : D7
To Be Published

 

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