Author results

1K9I
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COMPLEX OF DC-SIGN AND GLCNAC2MAN3
Descriptor:mDC-SIGN1B type I isoform, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
Authors:Feinberg, H., Mitchell, D.A., Drickamer, K., Weis, W.I.
Deposit date:2001-10-29
Release date:2001-12-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for selective recognition of oligosaccharides by DC-SIGN and DC-SIGNR.
Science, 294, 2001
1K9J
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COMPLEX OF DC-SIGNR AND GLCNAC2MAN3
Descriptor:mDC-SIGN2 TYPE I ISOFORM, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
Authors:Feinberg, H., Mitchell, D.A., Drickamer, K., Weis, W.I.
Deposit date:2001-10-29
Release date:2001-12-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for selective recognition of oligosaccharides by DC-SIGN and DC-SIGNR.
Science, 294, 2001
1SL4
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CRYSTAL STRUCTURE OF DC-SIGN CARBOHYDRATE RECOGNITION DOMAIN COMPLEXED WITH MAN4
Descriptor:mDC-SIGN1B type I isoform, ALPHA-D-MANNOSE, CALCIUM ION
Authors:Guo, Y., Feinberg, H., Conroy, E., Mitchell, D.A., Alvarez, R., Blixt, O., Taylor, M.E., Weis, W.I., Drickamer, K.
Deposit date:2004-03-05
Release date:2004-06-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural basis for distinct ligand-binding and targeting properties of the receptors DC-SIGN and DC-SIGNR
Nat.Struct.Mol.Biol., 11, 2004
1SL5
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CRYSTAL STRUCTURE OF DC-SIGN CARBOHYDRATE RECOGNITION DOMAIN COMPLEXED WITH LNFP III (DEXTRA L504).
Descriptor:mDC-SIGN1B type I isoform, BETA-D-GALACTOSE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Guo, Y., Feinberg, H., Conroy, E., Mitchell, D.A., Alvarez, R., Blixt, O., Taylor, M.E., Weis, W.I., Drickamer, K.
Deposit date:2004-03-05
Release date:2004-06-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for distinct ligand-binding and targeting properties of the receptors DC-SIGN and DC-SIGNR
Nat.Struct.Mol.Biol., 11, 2004
1SL6
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CRYSTAL STRUCTURE OF A FRAGMENT OF DC-SIGNR (CONTAING THE CARBOHYDRATE RECOGNITION DOMAIN AND TWO REPEATS OF THE NECK) COMPLEXED WITH LEWIS-X.
Descriptor:C-type lectin DC-SIGNR, BETA-D-GALACTOSE, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ...
Authors:Guo, Y., Feinberg, H., Conroy, E., Mitchell, D.A., Alvarez, R., Blixt, O., Taylor, M.E., Weis, W.I., Drickamer, K.
Deposit date:2004-03-05
Release date:2004-06-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis for distinct ligand-binding and targeting properties of the receptors DC-SIGN and DC-SIGNR
Nat.Struct.Mol.Biol., 11, 2004
1XAR
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CRYSTAL STRUCTURE OF A FRAGMENT OF DC-SIGNR (CONTAINING THE CARBOHYDRATE RECOGNITION DOMAIN AND TWO REPEATS OF THE NECK).
Descriptor:CD209 antigen-like protein 1, SODIUM ION
Authors:Feinberg, H., Guo, Y., Mitchell, D.A., Drickamer, K., Weis, W.I.
Deposit date:2004-08-26
Release date:2004-11-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Extended Neck Regions Stabilize Tetramers of the Receptors DC-SIGN and DC-SIGNR
J.Biol.Chem., 280, 2005
2MW3
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SOLUTION NMR STRUCTURE OF THE LASSO PEPTIDE STREPTOMONOMICIN
Descriptor:Lasso peptide
Authors:Tietz, J.I., Zhu, L., Mitchell, D.A., Metelev, M., Melby, J.O., Blair, P.M., Livnat, I., Severinov, K.
Deposit date:2014-10-24
Release date:2015-01-28
Last modified:2015-03-04
Method:SOLUTION NMR
Cite:Structure, bioactivity, and resistance mechanism of streptomonomicin, an unusual lasso Peptide from an understudied halophilic actinomycete.
Chem.Biol., 22, 2015
5JPL
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LP2006, A HANDCUFF-TOPOLOGY LASSO PEPTIDE ANTIBIOTIC
Descriptor:Uncharacterized protein
Authors:Tietz, J.I., Schwalen, C.J., Blair, P.M., Zakai, U.I., Mitchell, D.A.
Deposit date:2016-05-03
Release date:2017-03-01
Last modified:2017-04-26
Method:SOLUTION NMR
Cite:A new genome-mining tool redefines the lasso peptide biosynthetic landscape.
Nat. Chem. Biol., 13, 2017
6F1C
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C1RC1S COMPLEX
Descriptor:Complement C1r subcomponent, Complement C1s subcomponent, CALCIUM ION, ...
Authors:Almitairi, J.O.M., Venkatraman Girija, U., Furze, C.M., Simpson-Gray, X., Badakshi, F., Marshall, J.E., Mitchell, D.A., Moody, P.C.E., Wallis, R.
Deposit date:2017-11-21
Release date:2018-01-17
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Structure of the C1r-C1s interaction of the C1 complex of complement activation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6F1D
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CUB2 DOMAIN OF C1R
Descriptor:Complement C1r subcomponent, CALCIUM ION, SODIUM ION
Authors:Almitairi, J.O.M., Venkatraman Girija, U., Furze, C.M., Simpson-Gray, X., Badakshi, F., Marshall, J.E., Mitchell, D.A., Moody, P.C.E., Wallis, R.
Deposit date:2017-11-21
Release date:2018-01-17
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure of the C1r-C1s interaction of the C1 complex of complement activation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6F1H
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C1RC1S COMPLEX
Descriptor:Complement C1r subcomponent, Complement C1s subcomponent, CALCIUM ION, ...
Authors:Almitairi, J.O.M., Venkatraman Girija, U., Furze, C.M., Simpson-Gray, X., Badakshi, F., Marshall, J.E., Mitchell, D.A., Moody, P.C.E., Wallis, R.
Deposit date:2017-11-22
Release date:2018-01-17
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Structure of the C1r-C1s interaction of the C1 complex of complement activation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6F39
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C1R HOMODIMER CUB1-EGF-CUB2
Descriptor:Complement C1r subcomponent, CALCIUM ION, SODIUM ION, ...
Authors:Almitairi, J.O.M., Venkatraman Girija, U., Furze, C.M., Simpson-Gray, X., Badakshi, F., Marshall, J.E., Mitchell, D.A., Moody, P.C.E., Wallis, R.
Deposit date:2017-11-28
Release date:2018-01-24
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (5.801 Å)
Cite:Structure of the C1r-C1s interaction of the C1 complex of complement activation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
3POB
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CRYSTAL STRUCTURE OF MASP-1 CUB2 DOMAIN IN COMPLEX WITH THE COLLAGEN-LIKE DOMAIN OF MBL
Descriptor:Mannan-binding lectin serine protease 1, MBL collagen-like peptide, CALCIUM ION
Authors:Gingras, A.R., Moody, P.C.E., Wallis, R.
Deposit date:2010-11-22
Release date:2011-08-24
Last modified:2011-11-30
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Structural Basis of Mannan-Binding Lectin Recognition by Its Associated Serine Protease MASP-1: Implications for Complement Activation.
Structure, 19, 2011
3POD
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CRYSTAL STRUCTURE OF MBL COLLAGEN-LIKE PEPTIDE
Descriptor:MBL collagen-like peptide
Authors:Gingras, A.R., Moody, P.C.E., Wallis, R.
Deposit date:2010-11-22
Release date:2011-08-24
Last modified:2011-11-30
Method:X-RAY DIFFRACTION (1.497 Å)
Cite:Structural Basis of Mannan-Binding Lectin Recognition by Its Associated Serine Protease MASP-1: Implications for Complement Activation.
Structure, 19, 2011
3POE
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CRYSTAL STRUCTURE OF THE MASP-1 CUB2 DOMAIN BOUND TO CA2+
Descriptor:Mannan-binding lectin serine protease 1, CALCIUM ION
Authors:Gingras, A.R., Moody, P.C.E., Wallis, R.
Deposit date:2010-11-22
Release date:2011-08-24
Last modified:2011-11-30
Method:X-RAY DIFFRACTION (1.501 Å)
Cite:Structural Basis of Mannan-Binding Lectin Recognition by Its Associated Serine Protease MASP-1: Implications for Complement Activation.
Structure, 19, 2011
3POF
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CRYSTAL STRUCTURE OF MASP-1 CUB2 DOMAIN BOUND TO CA2+
Descriptor:Mannan-binding lectin serine protease 1, CALCIUM ION, SULFATE ION, ...
Authors:Gingras, A.R., Moody, P.C.E., Wallis, R.
Deposit date:2010-11-22
Release date:2011-08-24
Last modified:2011-11-30
Method:X-RAY DIFFRACTION (1.501 Å)
Cite:Structural Basis of Mannan-Binding Lectin Recognition by Its Associated Serine Protease MASP-1: Implications for Complement Activation.
Structure, 19, 2011
3POG
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CRYSTAL STRUCTURE OF THE MASP-1 CUB2 DOMAIN BOUND TO CA2+
Descriptor:Mannan-binding lectin serine protease 1, CALCIUM ION
Authors:Gingras, A.R., Moody, P.C.E., Wallis, R.
Deposit date:2010-11-22
Release date:2011-08-24
Last modified:2011-11-30
Method:X-RAY DIFFRACTION (2.749 Å)
Cite:Structural Basis of Mannan-Binding Lectin Recognition by Its Associated Serine Protease MASP-1: Implications for Complement Activation.
Structure, 19, 2011
3POI
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CRYSTAL STRUCTURE OF MASP-1 CUB2 DOMAIN BOUND TO METHYLAMINE
Descriptor:Mannan-binding lectin serine protease 1, CALCIUM ION, METHYLAMINE, ...
Authors:Gingras, A.R., Moody, P.C.E., Wallis, R.
Deposit date:2010-11-22
Release date:2011-08-24
Last modified:2011-11-30
Method:X-RAY DIFFRACTION (1.701 Å)
Cite:Structural Basis of Mannan-Binding Lectin Recognition by Its Associated Serine Protease MASP-1: Implications for Complement Activation.
Structure, 19, 2011
3POJ
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CRYSTAL STRUCTURE OF MASP-1 CUB2 DOMAIN BOUND TO ETHYLAMINE
Descriptor:Mannan-binding lectin serine protease 1, CALCIUM ION, ETHANAMINE, ...
Authors:Gingras, A.R., Moody, P.C.E., Wallis, R.
Deposit date:2010-11-22
Release date:2011-08-24
Last modified:2011-11-30
Method:X-RAY DIFFRACTION (1.451 Å)
Cite:Structural Basis of Mannan-Binding Lectin Recognition by Its Associated Serine Protease MASP-1: Implications for Complement Activation.
Structure, 19, 2011
3PON
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CRYSTAL STRUCTURE OF MBL COLLAGEN-LIKE PEPTIDE
Descriptor:MBL collagen-like peptide
Authors:Gingras, A.R., Moody, P.C.E., Wallis, R.
Deposit date:2010-11-23
Release date:2011-08-24
Last modified:2011-11-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Basis of Mannan-Binding Lectin Recognition by Its Associated Serine Protease MASP-1: Implications for Complement Activation.
Structure, 19, 2011
3SGT
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CRYSTAL STRUCTURE OF E. COLI UNDECAPRENYL PYROPHOSPHATE SYNTHASE IN COMPLEX WITH BPH-1299
Descriptor:Undecaprenyl pyrophosphate synthase, 2-{[4-(3,4-dimethylphenoxy)phenyl]carbamoyl}benzoic acid
Authors:Cao, R., Liu, Y.-L., Oldfield, E.
Deposit date:2011-06-15
Release date:2012-12-19
Last modified:2013-01-16
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Antibacterial drug leads targeting isoprenoid biosynthesis.
Proc.Natl.Acad.Sci.USA, 110, 2013
3SGV
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CRYSTAL STRUCTURE OF E. COLI UNDECAPRENYL PYROPHOSPHATE SYNTHASE IN COMPLEX WITH BPH-1290
Descriptor:Undecaprenyl pyrophosphate synthase, 2-{[3-(3,4-dimethylphenoxy)phenyl]carbamoyl}-4-nitrobenzoic acid
Authors:Cao, R., Liu, Y.-L., Oldfield, E.
Deposit date:2011-06-15
Release date:2012-12-19
Last modified:2013-01-16
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Antibacterial drug leads targeting isoprenoid biosynthesis.
Proc.Natl.Acad.Sci.USA, 110, 2013
3SGX
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CRYSTAL STRUCTURE OF E. COLI UNDECAPRENYL PYROPHOSPHATE SYNTHASE IN COMPLEX WITH BPH-1100
Descriptor:Undecaprenyl pyrophosphate synthase, 4-{3-[(biphenyl-4-ylcarbonyl)amino]phenoxy}benzene-1,2-dicarboxylic acid
Authors:Cao, R., Liu, Y.-L., Oldfield, E.
Deposit date:2011-06-15
Release date:2012-12-19
Last modified:2013-01-16
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Antibacterial drug leads targeting isoprenoid biosynthesis.
Proc.Natl.Acad.Sci.USA, 110, 2013
3SH0
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CRYSTAL STRUCTURE OF E. COLI UNDECAPRENYL PYROPHOSPHATE SYNTHASE IN COMPLEX WITH BPH-1065
Descriptor:Undecaprenyl pyrophosphate synthase, 2-(dodecyloxy)-6-hydroxybenzoic acid
Authors:Cao, R., Liu, Y.-L., Oldfield, E.
Deposit date:2011-06-15
Release date:2012-12-19
Last modified:2013-01-16
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Antibacterial drug leads targeting isoprenoid biosynthesis.
Proc.Natl.Acad.Sci.USA, 110, 2013
3TH8
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STRUCTURE OF E. COLI UNDECAPRENYL DIPHOSPHATE SYNTHASE COMPLEXED WITH BPH-1063
Descriptor:Undecaprenyl pyrophosphate synthase, (2Z)-4-({3-[3-(hexyloxy)phenyl]propyl}amino)-2-hydroxy-4-oxobut-2-enoic acid
Authors:Cao, R., Zhu, W., Zhang, Y., Oldfield, E.
Deposit date:2011-08-18
Release date:2012-07-04
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.114 Å)
Cite:HIV-1 Integrase Inhibitor-Inspired Antibacterials Targeting Isoprenoid Biosynthesis.
ACS Med Chem Lett, 3, 2012
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