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The crystal structures at 2.2 angstroms resolution of hydroxyethylene-based inhibitors bound to human immunodeficiency virus type 1 protease show that the inhibitors are present in two distinct orientations
Descriptor:	HIV-1 PROTEASE, methyl N-{(4S,5S)-5-[(L-alanyl-L-alanyl)amino]-4-hydroxy-6-phenylhexanoyl}-L-valyl-L-valinate
Authors:	Murthy, K, Winborne, E.L, Minnich, M.D, Culp, J.S, Debouck, C.
Deposit date:	1992-09-21
Release date:	1994-05-31
Last modified:	2024-03-13
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	The crystal structures at 2.2-A resolution of hydroxyethylene-based inhibitors bound to human immunodeficiency virus type 1 protease show that the inhibitors are present in two distinct orientations. J.Biol.Chem., 267, 1992

The crystal structures at 2.2 angstroms resolution of hydroxyethylene-based inhibitors bound to human immunodeficiency virus type 1 protease show that the inhibitors are present in two distinct orientations
Descriptor:	HIV-1 PROTEASE, SKF 108738 PEPTIDE INHIBITOR
Authors:	Murthy, K, Winborne, E.L, Minnich, M.D, Culp, J.S, Debouck, C.
Deposit date:	1992-09-21
Release date:	1994-05-31
Last modified:	2023-11-15
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	The crystal structures at 2.2-A resolution of hydroxyethylene-based inhibitors bound to human immunodeficiency virus type 1 protease show that the inhibitors are present in two distinct orientations. J.Biol.Chem., 267, 1992

THREE-DIMENSIONAL STRUCTURE OF A SIV PROTEASE(SLASH)INHIBITOR COMPLEX. IMPLICATIONS FOR THE DESIGN OF HIV-1 AND HIV-2 PROTEASE INHIBITORS
Descriptor:	SIV PROTEASE, methyl N-{(4S,5S)-5-[(L-alanyl-L-alanyl)amino]-4-hydroxy-6-phenylhexanoyl}-L-valyl-L-valinate
Authors:	Zhao, B, Abdel-Meguid, S.
Deposit date:	1993-08-24
Release date:	1994-01-31
Last modified:	2024-02-14
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	Three-dimensional structure of a simian immunodeficiency virus protease/inhibitor complex. Implications for the design of human immunodeficiency virus type 1 and 2 protease inhibitors. Biochemistry, 32, 1993

INHIBITION OF HUMAN IMMUNODEFICIENCY VIRUS-1 PROTEASE BY A C2-SYMMETRIC PHOSPHINATE SYNTHESIS AND CRYSTALLOGRAPHIC ANALYSIS
Descriptor:	(2-PHENYL-1-CARBOBENZYL-OXYVALYL-AMINO)-ETHYL-PHOSPHINIC ACID, HIV-1 PROTEASE
Authors:	Abdel-Meguid, S, Zhao, B.
Deposit date:	1993-04-06
Release date:	1993-10-31
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Inhibition of human immunodeficiency virus-1 protease by a C2-symmetric phosphinate. Synthesis and crystallographic analysis. Biochemistry, 32, 1993