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1HQM
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CRYSTAL STRUCTURE OF THERMUS AQUATICUS CORE RNA POLYMERASE-INCLUDES COMPLETE STRUCTURE WITH SIDE-CHAINS (EXCEPT FOR DISORDERED REGIONS)-FURTHER REFINED FROM ORIGINAL DEPOSITION-CONTAINS ADDITIONAL SEQUENCE INFORMATION
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Minakhin, L., Bhagat, S., Brunning, A., Campbell, E.A., Darst, S.A., Ebright, R.H., Severinov, K.
Deposit date:2000-12-18
Release date:2001-02-07
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Bacterial RNA polymerase subunit omega and eukaryotic RNA polymerase subunit RPB6 are sequence, structural, and functional homologs and promote RNA polymerase assembly.
Proc.Natl.Acad.Sci.USA, 98, 2001
3WOD
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RNA POLYMERASE-GP39 COMPLEX
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Tagami, S., Sekine, S., Minakhin, L., Esyunina, D., Akasaka, R., Shirouzu, M., Kulbachinskiy, A., Severinov, K., Yokoyama, S.
Deposit date:2013-12-26
Release date:2014-03-12
Last modified:2015-03-25
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural basis for promoter specificity switching of RNA polymerase by a phage factor.
Genes Dev., 28, 2014
3WOE
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CRYSTAL STRUCTURE OF P23-45 GP39 (6-109) BOUND TO THERMUS THERMOPHILUS RNA POLYMERASE BETA-FLAP DOMAIN
Descriptor:DNA-directed RNA polymerase subunit beta, Putative uncharacterized protein
Authors:Tagami, S., Sekine, S., Minakhin, L., Esyunina, D., Akasaka, R., Shirouzu, M., Kulbachinskiy, A., Severinov, K., Yokoyama, S.
Deposit date:2013-12-26
Release date:2014-03-12
Last modified:2015-03-25
Method:X-RAY DIFFRACTION (2.351 Å)
Cite:Structural basis for promoter specificity switching of RNA polymerase by a phage factor.
Genes Dev., 28, 2014
3WOF
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CRYSTAL STRUCTURE OF P23-45 GP39 (6-132) BOUND TO THERMUS THERMOPHILUS RNA POLYMERASE BETA-FLAP DOMAIN
Descriptor:DNA-directed RNA polymerase subunit beta, Putative uncharacterized protein
Authors:Tagami, S., Sekine, S., Minakhin, L., Esyunina, D., Akasaka, R., Shirouzu, M., Kulbachinskiy, A., Severinov, K., Yokoyama, S.
Deposit date:2013-12-26
Release date:2014-03-12
Last modified:2015-03-25
Method:X-RAY DIFFRACTION (3.298 Å)
Cite:Structural basis for promoter specificity switching of RNA polymerase by a phage factor.
Genes Dev., 28, 2014
4ZJN
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CRYSTAL STRUCTURE OF THE BACTERIOPHAGE G20C PORTAL PROTEIN
Descriptor:Portal protein, (4S)-2-METHYL-2,4-PENTANEDIOL
Authors:Williams, L.S., Turkenburg, J.P., Levdikov, V.M., Minakhin, L., Severinov, K., Antson, A.A.
Deposit date:2015-04-29
Release date:2015-05-27
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Crystal structure of the bacteriophage G20C portal protein
To be published
5XJ0
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T. THERMOPHILUS RNA POLYMERASE HOLOENZYME BOUND WITH GP39 AND GP76
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Ooi, W.Y., Murayama, Y., Mekler, V., Minakhin, L., Severinov, K., Yokoyama, S., Sekine, S.
Deposit date:2017-04-28
Release date:2017-12-20
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (4.004 Å)
Cite:A Thermus phage protein inhibits host RNA polymerase by preventing template DNA strand loading during open promoter complex formation
Nucleic Acids Res., 46, 2018
6I9E
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THERMOPHAGE P23-45 EMPTY EXPANDED CAPSID
Descriptor:Major head protein, Auxiliary protein
Authors:Bayfield, O.W., Klimuk, E., Winkler, D.C., Hesketh, E.L., Chechik, M., Cheng, N., Dykeman, E.C., Minakhin, L., Ranson, N.A., Severinov, K., Steven, A.C., Antson, A.A.
Deposit date:2018-11-23
Release date:2019-02-06
Last modified:2019-03-06
Method:ELECTRON MICROSCOPY (3.74 Å)
Cite:Cryo-EM structure and in vitro DNA packaging of a thermophilic virus with supersized T=7 capsids.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6IBC
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THERMOPHAGE P23-45 PROCAPSID
Descriptor:Major head protein
Authors:Bayfield, O.W., Klimuk, E., Winkler, D.C., Hesketh, E.L., Chechik, M., Cheng, N., Dykeman, E.C., Minakhin, L., Ranson, N.A., Severinov, K., Steven, A.C., Antson, A.A.
Deposit date:2018-11-29
Release date:2019-02-13
Last modified:2019-03-06
Method:ELECTRON MICROSCOPY (4.39 Å)
Cite:Cryo-EM structure and in vitro DNA packaging of a thermophilic virus with supersized T=7 capsids.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6IBG
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BACTERIOPHAGE G20C PORTAL PROTEIN CRYSTAL STRUCTURE FOR CONSTRUCT WITH INTACT N-TERMINUS
Descriptor:Portal protein, (4S)-2-METHYL-2,4-PENTANEDIOL
Authors:Bayfield, O.W., Klimuk, E., Winkler, D.C., Hesketh, E.L., Chechik, M., Cheng, N., Dykeman, E.C., Minakhin, L., Ranson, N.A., Severinov, K., Steven, A.C., Antson, A.A.
Deposit date:2018-11-30
Release date:2019-01-23
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Cryo-EM structure and in vitro DNA packaging of a thermophilic virus with supersized T=7 capsids.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
5M1F
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CRYSTAL STRUCTURE OF THE LARGE TERMINASE NUCLEASE FROM THERMOPHILIC PHAGE G20C
Descriptor:Phage terminase large subunit
Authors:Xu, R.G., Jenkins, H.T., Chechik, M., Blagova, E.V., Greive, S.J., Antson, A.A.
Deposit date:2016-10-07
Release date:2016-10-26
Last modified:2017-05-03
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Viral genome packaging terminase cleaves DNA using the canonical RuvC-like two-metal catalysis mechanism.
Nucleic Acids Res., 45, 2017
5M1K
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CRYSTAL STRUCTURE OF THE LARGE TERMINASE NUCLEASE FROM THERMOPHILIC PHAGE G20C WITH BOUND MAGNESIUM
Descriptor:Phage terminase large subunit, SULFATE ION, MAGNESIUM ION, ...
Authors:Xu, R.G., Jenkins, H.T., Chechik, M., Blagova, E.V., Greive, S.J., Antson, A.A.
Deposit date:2016-10-09
Release date:2016-10-26
Last modified:2017-05-03
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Viral genome packaging terminase cleaves DNA using the canonical RuvC-like two-metal catalysis mechanism.
Nucleic Acids Res., 45, 2017
5M1N
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CRYSTAL STRUCTURE OF THE LARGE TERMINASE NUCLEASE FROM THERMOPHILIC PHAGE G20C WITH BOUND MANGANESE
Descriptor:Phage terminase large subunit, SULFATE ION, MANGANESE (II) ION, ...
Authors:Xu, R.G., Jenkins, H.T., Chechik, M., Blagova, E.V., Greive, S.J., Antson, A.A.
Deposit date:2016-10-09
Release date:2016-10-26
Last modified:2017-05-03
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Viral genome packaging terminase cleaves DNA using the canonical RuvC-like two-metal catalysis mechanism.
Nucleic Acids Res., 45, 2017
5M1O
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CRYSTAL STRUCTURE OF THE LARGE TERMINASE NUCLEASE FROM THERMOPHILIC PHAGE G20C WITH BOUND COBALT
Descriptor:Phage terminase large subunit, COBALT (II) ION
Authors:Xu, R.G., Jenkins, H.T., Chechik, M., Blagova, E.V., Greive, S.J., Antson, A.A.
Deposit date:2016-10-09
Release date:2016-10-26
Last modified:2017-05-03
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Viral genome packaging terminase cleaves DNA using the canonical RuvC-like two-metal catalysis mechanism.
Nucleic Acids Res., 45, 2017
5M1P
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CRYSTAL STRUCTURE OF THE LARGE TERMINASE NUCLEASE FROM THERMOPHILIC PHAGE G20C WITH BOUND CALCIUM
Descriptor:Terminase large subunit, CALCIUM ION
Authors:Xu, R.G., Jenkins, H.T., Chechik, M., Blagova, E.V., Greive, S.J., Antson, A.A.
Deposit date:2016-10-09
Release date:2016-10-26
Last modified:2017-05-03
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Viral genome packaging terminase cleaves DNA using the canonical RuvC-like two-metal catalysis mechanism.
Nucleic Acids Res., 45, 2017
5M1Q
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CRYSTAL STRUCTURE OF THE LARGE TERMINASE NUCLEASE FROM THERMOPHILIC PHAGE G20C WITH BOUND ZINC
Descriptor:Phage terminase large subunit, ZINC ION
Authors:Xu, R.G., Jenkins, H.T., Chechik, M., Blagova, E.V., Greive, S.J., Antson, A.A.
Deposit date:2016-10-09
Release date:2016-10-26
Last modified:2017-05-03
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Viral genome packaging terminase cleaves DNA using the canonical RuvC-like two-metal catalysis mechanism.
Nucleic Acids Res., 45, 2017