Author results

1DPL
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A-DNA DECAMER GCGTA(T23)TACGC WITH INCORPORATED 2'-METHOXY-3'-METHYLENEPHOSPHATE-THYMIDINE
Descriptor:5'-D(*GP*CP*GP*TP*AP*(T23)P*AP*CP*GP*C)-3', MAGNESIUM ION, SPERMINE
Authors:Egli, M., Tereshko, V., Teplova, M., Minasov, G., Joachimiak, A., Sanishvili, R., Weeks, C.M., Miller, R., Maier, M.A., An, H., Dan Cook, P., Manoharan, M.
Deposit date:1999-12-27
Release date:2000-04-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (0.83 Å)
Cite:X-ray crystallographic analysis of the hydration of A- and B-form DNA at atomic resolution.
Biopolymers, 48, 1998
1DPN
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B-DODECAMER CGCGAA(TAF)TCGCG WITH INCORPORATED 2'-DEOXY-2'-FLUORO-ARABINO-FURANOSYL THYMINE
Descriptor:DNA (5'-D(*CP*GP*CP*GP*AP*AP*(TAF)P*TP*CP*GP*CP*G)-3'), MAGNESIUM ION
Authors:Egli, M., Tereshko, V., Teplova, M., Minasov, G., Joachimiak, A., Sanishvili, R., Weeks, C.M., Miller, R., Maier, M.A., An, H., Dan Cook, P., Manoharan, M.
Deposit date:1999-12-27
Release date:2000-04-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:X-ray crystallographic analysis of the hydration of A- and B-form DNA at atomic resolution.
Biopolymers, 48, 1998
1A0M
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1.1 ANGSTROM CRYSTAL STRUCTURE OF A-CONOTOXIN [TYR15]-EPI
Descriptor:ALPHA-CONOTOXIN [TYR15]-EPI
Authors:Hu, S.-H., Loughnan, M., Miller, R., Weeks, C.M., Blessing, R.H., Alewood, P.F., Lewis, R.J., Martin, J.L.
Deposit date:1997-12-03
Release date:1999-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:The 1.1 A resolution crystal structure of [Tyr15]EpI, a novel alpha-conotoxin from Conus episcopatus, solved by direct methods.
Biochemistry, 37, 1998
1AHO
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THE AB INITIO STRUCTURE DETERMINATION AND REFINEMENT OF A SCORPION PROTEIN TOXIN
Descriptor:TOXIN II
Authors:Smith, G.D., Blessing, R.H., Ealick, S.E., Fontecilla-Camps, J.C., Hauptman, H.A., Housset, D., Langs, D.A., Miller, R.
Deposit date:1997-04-08
Release date:1997-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (0.96 Å)
Cite:Ab initio structure determination and refinement of a scorpion protein toxin.
Acta Crystallogr.,Sect.D, 53, 1997
3PE6
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CRYSTAL STRUCTURE OF A SOLUBLE FORM OF HUMAN MGLL IN COMPLEX WITH AN INHIBITOR
Descriptor:Monoglyceride lipase, (2-cyclohexyl-1,3-benzoxazol-6-yl){3-[4-(pyrimidin-2-yl)piperazin-1-yl]azetidin-1-yl}methanone
Authors:Schubert, C., Schalk-Hih, C.
Deposit date:2010-10-25
Release date:2011-03-02
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Crystal structure of a soluble form of human monoglyceride lipase in complex with an inhibitor at 1.35 A resolution.
Protein Sci., 20, 2011
5KQ5
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AMPK BOUND TO ALLOSTERIC ACTIVATOR
Descriptor:5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit gamma-1, ...
Authors:Calabrese, M.F., Kurumbail, R.G.
Deposit date:2016-07-05
Release date:2016-08-17
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.41 Å)
Cite:Discovery and Preclinical Characterization of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic Acid (PF-06409577), a Direct Activator of Adenosine Monophosphate-activated Protein Kinase (AMPK), for the Potential Treatment of Diabetic Nephropathy.
J.Med.Chem., 59, 2016
6E4T
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STRUCTURE OF AMPK BOUND TO ACTIVATOR
Descriptor:5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit gamma-1, ...
Authors:Calabrese, M.F., Kurumbail, R.G.
Deposit date:2018-07-18
Release date:2018-08-08
Last modified:2018-09-05
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Acyl Glucuronide Metabolites of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1 H-indole-3-carboxylic Acid (PF-06409577) and Related Indole-3-carboxylic Acid Derivatives are Direct Activators of Adenosine Monophosphate-Activated Protein Kinase (AMPK).
J. Med. Chem., 61, 2018
6E4U
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STRUCTURE OF AMPK BOUND TO ACTIVATOR
Descriptor:5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit gamma-1, ...
Authors:Calabrese, M.F., Kurumbail, R.G.
Deposit date:2018-07-18
Release date:2018-08-08
Last modified:2018-09-05
Method:X-RAY DIFFRACTION (3.27 Å)
Cite:Acyl Glucuronide Metabolites of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1 H-indole-3-carboxylic Acid (PF-06409577) and Related Indole-3-carboxylic Acid Derivatives are Direct Activators of Adenosine Monophosphate-Activated Protein Kinase (AMPK).
J. Med. Chem., 61, 2018
6E4W
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STRUCTURE OF AMPK BOUND TO ACTIVATOR
Descriptor:5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit gamma-1, ...
Authors:Calabrese, M.F., Kurumbail, R.G.
Deposit date:2018-07-18
Release date:2018-08-08
Last modified:2018-09-05
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Acyl Glucuronide Metabolites of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1 H-indole-3-carboxylic Acid (PF-06409577) and Related Indole-3-carboxylic Acid Derivatives are Direct Activators of Adenosine Monophosphate-Activated Protein Kinase (AMPK).
J. Med. Chem., 61, 2018
1PEN
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ALPHA-CONOTOXIN PNI1
Descriptor:ALPHA-CONOTOXIN PNIA
Authors:Hu, S.-H., Gehrmann, J., Guddat, L.W., Alewood, P.F., Craik, D.J., Martin, J.L.
Deposit date:1996-01-29
Release date:1997-04-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:The 1.1 A crystal structure of the neuronal acetylcholine receptor antagonist, alpha-conotoxin PnIA from Conus pennaceus.
Structure, 4, 1996
1AKG
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ALPHA-CONOTOXIN PNIB FROM CONUS PENNACEUS
Descriptor:ALPHA-CONOTOXIN PNIB
Authors:Hu, S.-H., Martin, J.L.
Deposit date:1997-05-18
Release date:1998-05-20
Last modified:2015-06-10
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Crystal structure at 1.1 A resolution of alpha-conotoxin PnIB: comparison with alpha-conotoxins PnIA and GI.
Biochemistry, 36, 1997