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5MU8
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BU of 5mu8 by Molmil
HUMAN TNF-ALPHA IN COMPLEX WITH JNJ525
Descriptor: Tumor necrosis factor, ~{N}4-(phenylmethyl)-~{N}4-[2-[3-(2-piperazin-1-ylpyrimidin-5-yl)phenyl]phenyl]pyrimidine-2,4-diamine
Authors:Blevitt, J.M, Hack, M.D, Herman, K.L, Jackson, P.F, Krawczuk, P.J, Lebsack, A.D, Liu, A.X, Mirzadegan, T, Nelen, M.I, Patrick, A.P, Steinbacher, S, Milla, M.E, Lumb, K.J.
Deposit date:2017-01-12
Release date:2017-03-29
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Basis of Small-Molecule Aggregate Induced Inhibition of a Protein-Protein Interaction.
J. Med. Chem., 60, 2017
7M2G
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BU of 7m2g by Molmil
INTERLEUKIN-2 (human) mutant P65K, C125S
Descriptor: GLYCEROL, Interleukin-2, SULFATE ION
Authors:Ptacin, J.L, Milla, M.E, Steinbacher, S, Maskos, K, Thomsen, M.
Deposit date:2021-03-16
Release date:2021-08-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:An engineered IL-2 reprogrammed for anti-tumor therapy using a semi-synthetic organism.
Nat Commun, 12, 2021
1MYK
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BU of 1myk by Molmil
CRYSTAL STRUCTURE, FOLDING, AND OPERATOR BINDING OF THE HYPERSTABLE ARC REPRESSOR MUTANT PL8
Descriptor: ARC REPRESSOR
Authors:Schildbach, J.F, Milla, M.E, Jeffrey, P.D, Raumann, B.E, Sauer, R.T.
Deposit date:1994-10-12
Release date:1995-01-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure, folding, and operator binding of the hyperstable Arc repressor mutant PL8.
Biochemistry, 34, 1995

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