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3O4L
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BU of 3o4l by Molmil
Genetic and structural basis for selection of a ubiquitous T cell receptor deployed in Epstein-Barr virus
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BSLF2/BMLF1 protein, Beta-2-microglobulin, ...
Authors:Miles, J.J, Bulek, A.M, Cole, D.K, Gostick, E, Schauenburg, J.A, Dolton, G, Venturi, V, Davenport, M.P, Tan, M.P, Burrows, S.R, Wooldridge, L, Price, D.A, Rizkallah, P.J, Sewell, A.K.
Deposit date:2010-07-27
Release date:2011-01-12
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Genetic and structural basis for selection of a ubiquitous T cell receptor deployed in Epstein-Barr virus infection.
Plos Pathog., 6, 2010
2FYY
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BU of 2fyy by Molmil
The role of T cell receptor alpha genes in directing human MHC restriction
Descriptor: 11-mer peptide from Epstein-Barr nuclear antigen 1, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Miles, J.J, Borg, N.A.
Deposit date:2006-02-08
Release date:2006-12-26
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:TCR alpha genes direct MHC restriction in the potent human T cell response to a class I-bound viral epitope.
J Immunol., 177, 2006
1ZSD
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BU of 1zsd by Molmil
Crystal Structure Of HLA-B*3501 Presenting an 11-Mer EBV Antigen EPLPQGQLTAY
Descriptor: BZLF1 trans-activator protein, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Miles, J.J, Elhassen, D, Borg, N.A, Silins, S.L, Tynan, F.E, Burrows, J.M, Purcell, A.W, Kjer-Nielsen, L, Rossjohn, J, Burrows, S.R, McCluskey, J.
Deposit date:2005-05-24
Release date:2005-06-07
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:CTL Recognition of a Bulged Viral Peptide Involves Biased TCR Selection.
J.Immunol., 175, 2005
2FZ3
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BU of 2fz3 by Molmil
The role of T cell receptor alpha genes in directing human MHC restriction
Descriptor: 11-mer peptide from Epstein-Barr nuclear antigen 1, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Miles, J.J, Borg, N.A.
Deposit date:2006-02-09
Release date:2006-12-26
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:TCR alpha genes direct MHC restriction in the potent human T cell response to a class I-bound viral epitope.
J Immunol., 177, 2006
3MV8
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Crystal Structure of the TK3-Gln55His TCR in complex with HLA-B*3501/HPVG
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ...
Authors:Gras, S, Chen, Z, Miles, J.J, Liu, Y.C, Bell, M.J, Sullivan, L.C, Kjer-Nielsen, L, Brennan, R.M, Burrows, J.M, Neller, M.A, Khanna, R, Purcell, A.W, Brooks, A.G, McCluskey, J, Rossjohn, J, Burrows, S.R.
Deposit date:2010-05-03
Release date:2010-06-09
Last modified:2011-07-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Allelic polymorphism in the T cell receptor and its impact on immune responses
J.Exp.Med., 207, 2010
3MV9
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Crystal Structure of the TK3-Gln55Ala TCR in complex with HLA-B*3501/HPVG
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ...
Authors:Gras, S, Chen, Z, Miles, J.J, Liu, Y.C, Bell, M.J, Sullivan, L.C, Kjer-Nielsen, L, Brennan, R.M, Burrows, J.M, Neller, M.A, Khanna, R, Purcell, A.W, Brooks, A.G, McCluskey, J, Rossjohn, J, Burrows, S.R.
Deposit date:2010-05-03
Release date:2010-06-09
Last modified:2011-07-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Allelic polymorphism in the T cell receptor and its impact on immune responses
J.Exp.Med., 207, 2010
3MV7
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Crystal Structure of the TK3 TCR in complex with HLA-B*3501/HPVG
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ...
Authors:Gras, S, Chen, Z, Miles, J.J, Liu, Y.C, Bell, M.J, Sullivan, L.C, Kjer-Nielsen, L, Brennan, R.M, Burrows, J.M, Neller, M.A, Khanna, R, Purcell, A.W, Brooks, A.G, McCluskey, J, Rossjohn, J, Burrows, S.R.
Deposit date:2010-05-03
Release date:2010-06-09
Last modified:2011-07-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Allelic polymorphism in the T cell receptor and its impact on immune responses
J.Exp.Med., 207, 2010
3HG1
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BU of 3hg1 by Molmil
Germline-governed recognition of a cancer epitope by an immunodominant human T cell receptor
Descriptor: Beta-2-microglobulin, CANCER/MART-1, GLYCEROL, ...
Authors:Cole, D.K, Yuan, F, Rizkallah, P.J, Miles, J.J, Gostick, E, Price, D.A, Gao, G.F, Jakobsen, B.K, Sewell, A.K.
Deposit date:2009-05-13
Release date:2009-07-28
Last modified:2014-04-09
Method:X-RAY DIFFRACTION (3 Å)
Cite:Germ line-governed recognition of a cancer epitope by an immunodominant human T-cell receptor.
J.Biol.Chem., 284, 2009
1ZHL
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BU of 1zhl by Molmil
Crystal structure of HLA-B*3508 presenting 13-mer EBV antigen LPEPLPQGQLTAY
Descriptor: Beta-2-microglobulin, EBV-peptide LPEPLPQGQLTAY, HLA class I histocompatibility antigen, ...
Authors:Tynan, F.E, Borg, N.A, Miles, J.J, Beddoe, T, El-Hassen, D, Silins, S.L, van Zuylen, W.J, Purcell, A.W, Kjer-Nielsen, L, McCluskey, J, Burrows, S.R, Rossjohn, J.
Deposit date:2005-04-26
Release date:2005-05-17
Last modified:2014-04-16
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The high resolution structures of highly bulged viral epitopes bound to the major histocompatability class I: Implications for T-cell receptor engagement and T-cell immunodominance
J.Biol.Chem., 280, 2005
1ZHK
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BU of 1zhk by Molmil
Crystal structure of HLA-B*3501 presenting 13-mer EBV antigen LPEPLPQGQLTAY
Descriptor: Beta-2-microglobulin, EBV-peptide LPEPLPQGQLTAY, HLA class I histocompatibility antigen, ...
Authors:Tynan, F.E, Borg, N.A, Miles, J.J, Beddoe, T, El-Hassen, D, Silins, S.L, van Zuylen, W.J, Purcell, A.W, Kjer-Nielsen, L, McCluskey, J, Burrows, S.R, Rossjohn, J.
Deposit date:2005-04-26
Release date:2005-05-17
Last modified:2014-04-16
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The high resolution structures of highly bulged viral epitopes bound to the major histocompatability class I: Implications for T-cell receptor engagement and T-cell immunodominance
J.Biol.Chem., 280, 2005
2AXG
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BU of 2axg by Molmil
The Immunogenicity of a Viral Cytotoxic T Cell Epitope is controlled by its MHC-bound Conformation
Descriptor: 10-mer peptide from BZLF1 trans-activator protein, ACETIC ACID, Beta-2-microglobulin, ...
Authors:Tynan, F.E, Elhassen, D, Purcell, A.W, Burrows, J.M, Borg, N.A, Miles, J.J, Williamson, N.A, Green, K.J, Tellam, J, Kjer-Nielsen, L, McCluskey, J, Rossjohn, J, Burrows, S.R.
Deposit date:2005-09-05
Release date:2005-11-29
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:The immunogenicity of a viral cytotoxic T cell epitope is controlled by its MHC-bound conformation
J.Exp.Med., 202, 2005
2AK4
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BU of 2ak4 by Molmil
Crystal Structure of SB27 TCR in complex with HLA-B*3508-13mer peptide
Descriptor: Beta-2-microglobulin, EBV peptide LPEPLPQGQLTAY, HLA-B35 variant, ...
Authors:Tynan, F.E, Burrows, S.R, Buckle, A.M, Clements, C.S, Borg, N.A, Miles, J.J, Beddoe, T, Whisstock, J.C, Wilce, M.C, Silins, S.L, Burrows, J.M, Kjer-Nielsen, L, Konstenko, L, Purcell, A.W, McCluskey, J, Rossjohn, J.
Deposit date:2005-08-03
Release date:2005-10-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide
Nat.Immunol., 6, 2005
2AXF
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BU of 2axf by Molmil
The Immunogenicity of a Viral Cytotoxic T Cell Epitope is controlled by its MHC-bound Conformation
Descriptor: 10-mer peptide from BZLF1 trans-activator protein, ACETIC ACID, Beta-2-microglobulin, ...
Authors:Tynan, F.E, Elhassen, D, Purcell, A.W, Burrows, J.M, Borg, N.A, Miles, J.J, Williamson, N.A, Green, K.J, Tellam, J, Kjer-Nielsen, L, McCluskey, J, Rossjohn, J, Burrows, S.R.
Deposit date:2005-09-05
Release date:2005-11-29
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The immunogenicity of a viral cytotoxic T cell epitope is controlled by its MHC-bound conformation
J.Exp.Med., 202, 2005
3BW9
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BU of 3bw9 by Molmil
Crystal Structure of HLA B*3508 in complex with a HCMV 12-mer peptide from the pp65 protein
Descriptor: Beta-2-microglobulin, CPS peptide from 65 kDa lower matrix phosphoprotein, HLA class I histocompatibility antigen, ...
Authors:Wynn, K.K, Marland, Z, Cooper, L, Silins, S.L, Gras, S, Archbold, J.K, Tynan, F.E, Miles, J.J, McCluskey, J, Burrows, S.R, Rossjohn, J, Khanna, R.
Deposit date:2008-01-08
Release date:2008-04-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Impact of clonal competition for peptide-MHC complexes on the CD8+ T-cell repertoire selection in a persistent viral infection
Blood, 111, 2008
3BWA
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BU of 3bwa by Molmil
Crystal Structure of HLA B*3508 in complex with a HCMV 8-mer peptide from the pp65 protein
Descriptor: Beta-2-microglobulin, FPT peptide from 65 kDa lower matrix phosphoprotein, HLA class I histocompatibility antigen, ...
Authors:Wynn, K.K, Marland, Z, Cooper, L, Silins, S.L, Gras, S, Archbold, J.K, Tynan, F.E, Miles, J.J, McCluskey, J, Burrows, S.R, Rossjohn, J, Khanna, R.
Deposit date:2008-01-08
Release date:2008-04-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Impact of clonal competition for peptide-MHC complexes on the CD8+ T-cell repertoire selection in a persistent viral infection
Blood, 111, 2008
4L4T
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BU of 4l4t by Molmil
Structure of human MAIT TCR in complex with human MR1-6-FP
Descriptor: 2-amino-4-oxo-3,4-dihydropteridine-6-carbaldehyde, Beta-2-microglobulin, MAIT T-cell receptor alpha chain, ...
Authors:Patel, O, Kjer-Nielsen, L, Le Nours, J, Eckle, S.B.G, Birkinshaw, R.W, Beddoe, T, Corbett, A.J, Liu, L, Miles, J.J, Meehan, B, Reantragoon, R, Sandoval-Romero, M.L, Sullivan, L.C, Brooks, A.G, Chen, Z, Fairlie, D.P, McCluskey, J, Rossjohn, J.
Deposit date:2013-06-09
Release date:2013-07-17
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Recognition of vitamin B metabolites by mucosal-associated invariant T cells.
Nat Commun, 4, 2013
4L4V
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BU of 4l4v by Molmil
Structure of human MAIT TCR in complex with human MR1-RL-6-Me-7-OH
Descriptor: 1-deoxy-1-(7-hydroxy-6-methyl-2,4-dioxo-3,4-dihydropteridin-8(2H)-yl)-D-ribitol, Beta-2-microglobulin, GLYCEROL, ...
Authors:Patel, O, Kjer-Nielsen, L, Le Nours, J, Eckle, S.B.G, Birkinshaw, R.W, Beddoe, T, Corbett, A.J, Liu, L, Miles, J.J, Meehan, B, Reantragoon, R, Sandoval-Romero, M.L, Sullivan, L.C, Brooks, A.G, Chen, Z, Fairlie, D.P, McCluskey, J, Rossjohn, J.
Deposit date:2013-06-09
Release date:2013-07-17
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Recognition of vitamin B metabolites by mucosal-associated invariant T cells.
Nat Commun, 4, 2013
7K1M
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BU of 7k1m by Molmil
Peptide from stony coral Heliofungia actiniformis: Hact-1
Descriptor: GLY-CYS-HIS-TYR-THR-PRO-PHE-GLY-LEU-ILE-CYS-PHE peptide
Authors:Daly, N.L, Schmidt, C.A.
Deposit date:2020-09-08
Release date:2020-11-25
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Identification and Characterization of a Peptide from the Stony Coral Heliofungia actiniformis .
J.Nat.Prod., 83, 2020
7L2G
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BU of 7l2g by Molmil
NMR solution structure of Nak1 from the Necator americanus hookworm
Descriptor: ShTK domain protein
Authors:Smallwood, T.B, Rosengren, K.J, Clark, R.J.
Deposit date:2020-12-17
Release date:2021-10-27
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Synthetic hookworm-derived peptides are potent modulators of primary human immune cell function that protect against experimental colitis in vivo.
J.Biol.Chem., 297, 2021
5NMK
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BU of 5nmk by Molmil
HLA A02 presenting SLFNTIAVL
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
Authors:Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
Deposit date:2017-04-06
Release date:2017-11-15
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope.
Front Immunol, 8, 2017
5NME
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BU of 5nme by Molmil
868 TCR in complex with HLA A02 presenting SLYNTVATL
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
Authors:Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
Deposit date:2017-04-05
Release date:2017-11-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.94 Å)
Cite:Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope.
Front Immunol, 8, 2017
5NMH
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BU of 5nmh by Molmil
HLA A02 presenting SLYNTIATL
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
Authors:Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
Deposit date:2017-04-05
Release date:2017-11-15
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope.
Front Immunol, 8, 2017
5NMF
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BU of 5nmf by Molmil
868 TCR in complex with HLA A02 presenting SLYNTIATL
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
Authors:Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
Deposit date:2017-04-05
Release date:2017-11-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope.
Front Immunol, 8, 2017
5NMG
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BU of 5nmg by Molmil
868 TCR in complex with HLA A02 presenting SLYFNTIAVL
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
Authors:Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
Deposit date:2017-04-05
Release date:2017-11-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope.
Front Immunol, 8, 2017
5NMD
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BU of 5nmd by Molmil
868 TCR Specific for HLA A02 presenting HIV Epitope SLYNTVATL
Descriptor: 1,2-ETHANEDIOL, Human T-cell Receptor, beta chain, ...
Authors:Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
Deposit date:2017-04-05
Release date:2017-11-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope.
Front Immunol, 8, 2017

 

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